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Comparison of the reverse bevel versus Franseen type endoscopic ultrasound needle

World Journal of Gastrointestinal Endoscopy 2020年第9期12卷 266-275页

作者： Chi Wing Chow Syeda Asma Haider Krish Ragunath Guruprasad P Aithal Martin W James Jacobo Ortiz-Fernandez-Sordo aloysious dominic aravinthan Suresh Vasan Venkatachalapathy National Institute for Health Research Nottingham Biomedical Research Centre Nottingham University Hospitals National Health Service Trust and University of NottinghamNottingham NG72UHUnited Kingdom Department of Pathology Nottingham University Hospitals National Health Service TrustNottingham NG72UHUnited Kingdom Nottingham Digestive Diseases Centre School of MedicineUniversity of NottinghamNottingham NG72RDUnited Kingdom National Institute for Health Research Nottingham Biomedical Research Centre Nottingham University Hospitals National Health Service Trust and University of NottinghamNottingham NG27UHUnited Kingdom

BACKGROUND Reverse bevel(RB)needle is widely used for endoscopic ultrasound fine needle biopsy(EUS-FNB).A 3-plane symmetrical needle with Franseen geometry(FG)has recently become *** To compare the clinical efficacy of FG to that of RB *** A retrospective cohort study of all adult patients who underwent EUS-FNB for solid and mixed lesions either with 22G RB needle or 22G FG needle between January 2016 and February 2019 was *** cytology slides were reviewed by an independent gastrointestinal cytopathologist blinded to the needle used and the initial cytology *** primary and secondary outcomes were to assess the sample adequacy using Euro-cytology criteria and the number of cell clusters,*** Two hundred and twenty six procedures were included in the *** needle was used in 128 procedures and FG needle in 98 *** baseline characteristics of both groups were *** multivariable analysis,FG needle(P=0.02)and location of the lesion(P<0.01)were independently associated with adequate ***,the use of FG needle(P=0.04)and the size of the lesion(P=0.02)were independently associated with acquisition of increased number of cell *** FG needle is superior to RB needle in acquiring adequate tissue and attaining higher number of cell clusters for solid and mixed lesions.

关键词： Endoscopic ultrasound Fine needle aspiration Fine needle biopsy Reverse bevel Franseen geometry Tissue acquisition

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Hepatic sarcoidosis complicating treatment-naive viral hepatitis

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World Journal of Hepatology 2012年第12期4卷 402-405页

作者： aloysious aravinthan William Gelso Anita Limbu Rebecca Brais Paul Richardson Department of Hepatology Cambridge University Hospitals NHS TrustCambridge CB2 0QQUnited Kingdom Department of Hepatology Cambridge University Hospitals NHS TrustCambridge CB2 0QQUnited Kingdom n Department of Histopathology Cambridge University Hospitals NHS TrustCambridge CB2 0QQUnited Kingdom Department of Hepatology The Royal Liverpool and Broadgreen University Hospitals NHS TrustLiverpool L7 8XPUnited Kingdom

Hepatic sarcoidosis is usually asymptomatic but rarely leads to adverse liver-related ***-existence of viral hepatitis and hepatic sarcoidosis is a rare,but recognised *** a balance between immune suppression and anti-viral therapy may be *** in the presence of viral hepatitis can lead to rapid deterioration of liver ***,anti-viral therapy may exacerbate granulomatous *** we present two cases of viral hepatitis co-existing with sarcoidosis that illustrate successful management *** one,hepatitis B replication was suppressed with oral antiviral therapy before commencing *** the second,remission of hepatic sarcoidosis was achieved with prednisolone,before treating hepatitis C and obtaining a sustained virological response with pegylated interferon and ribavirin therapy.

关键词： Hepatic sarcoidosis Chronic hepatitis C infection Chronic hepatitis B infection Immune suppression Anti-viral therapy

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