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Fate and Behavior of Tetracycline Resistance Genes in Activated Carbon Adsorption

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Journal of Water Resource and Protection 2024年第1期16卷 1-16页

作者： Sri Anggreini alma Rizky Aurellya Wenqing Li Fusheng Li Graduate School of Engineering Gifu University Gifu Japan Graduate School of Natural Science and Technology Gifu University Gifu Japan River Basin Research Center Gifu University Gifu Japan

The accessibility of tetracycline resistance gene (tetG) into the pores of activated carbon (AC), as well as the impact of the pore size distribution (PSD) of AC on the uptake capacity of tetG, were investigated using eight types of AC (four coal-based and four wood-based). AC showed the capability to admit tetG and the average reduction of tetG for coal-based and wood-based ACs at the AC dose of 1 g·L-1 was 3.12 log and 3.65 log, respectively. The uptake kinetic analysis showed that the uptake of the gene followed the pseudo-second-order kinetics reaction, and the uptake rate constant for the coal-based and wood-based ACs was in the range of 5.97 × 10-12 - 4.64 × 10-9 and 7.02 × 10-11 - 1.59 × 10-8 copies·mg-1·min-1, respectively. The uptake capacity analysis by fitting the obtained experiment data with the Freundlich isotherm model indicated that the uptake constant (KF) values were 1.71 × 103 - 8.00 × 109 (copies·g-1)1-1/n for coal-based ACs and 7.00 × 108 - 3.00 × 1010 (copies·g-1)1-1/n for wood-based ones. In addition, the correlation analysis between KF values and pore volume as well as pore surface at different pore size regions of ACs showed that relatively higher positive correlation was found for pores of 50 - 100 Å, suggesting ACs with more pores in this size region can uptake more tetG. The findings of this study are valuable as reference for optimizing the adsorption process regarding antibiotic resistance-related concerns in drinking water treatment.

关键词： Antibiotic Resistance Genes Adsorption Activated Carbon Drinking Water Treatment

Childhood Papillary Thyroid Carcinoma: A Case Report

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Case Reports in Clinical Medicine 2024年第4期13卷 108-114页

作者： alma Al Mansour Hayder Makki Hamadi Mahmoud Elshafey Mohamed Maryam Alkhatry Alqassemi Hospital Emirates Health Services Sharjah UAE Ibrahim Bin Hamad Obaidulla Hospital Ras Al Khaimah UAE

Background: Thyroid cancer is a rare disease yet the most common endocrine malignancy in pediatrics. Unlike adult patients, children with thyroid nodules typically don’t complain of pain, soreness, or difficulty swallowing. Additionally, using the recommended therapy for adults to treat paediatrics is not appropriate. There is an unmet need for updated unique guidelines for the management of papillary thyroid carcinoma (PTC) in paediatrics and adolescents. Case Report: A 12-year-old girl had an atypical presentation of metastatic PTC in lymph nodes. She was treated initially with hemi-thyroidectomy, followed by total thyroidectomy. A multidisciplinary team followed her up till successful results were found. Conclusion: Due to the difference in pathophysiology between thyroid tumors in children and adults, a unique approach to PTC management is to be implemented. Further trials are required for a better understanding of risk factors, the likelihood of recurrence, and the long-term side effects of the chosen management plan.

关键词： Papillary Thyroid Carcinoma Childhood Thyroidectomy Case Report

Addition of phenolic compounds to bread: antioxidant benefits and impact on food structure and sensory characteristics

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Food Production, Processing and Nutrition 2021年第1期3卷 314-325页

作者： Yesica A.Czajkowska–González Emilio Alvarez–Parrilla Nina del Rocío mart.nez–Ruiz alma A.Vázquez–Flores Marcela Gaytán–mart.nez Laura Ade la Rosa Departament of Chemical Biological Sciences Institute of Biomedical SciencesUniversidad Autónoma de Ciudad JuárezAnillo Envolvente del PRONAF y Estocolmos/nC.P.32310 Cd.JuárezMéxico Programa de Posgrado en Alimentos del Centro de la República(PROPAC) Research and Graduate Studies in Food ScienceSchool of ChemistryUniversidad Autónoma de QuerétaroCentro UniversitarioCerro de las Campanas S/NC.P.76010 Santiago de QuerétaroMexico

The use of flours or phenolic extracts obtained from non-traditional sources or agri-food industry by-products has been a strategy used to formulate new bakery products with characteristics of a functional ***,phenolic compounds present great structural diversity,as well as the ability to interact in a complex way with the macromolecules that constitute the bread ***,the addition of these flours,extracts or pure compounds produces various effects on the microstructure of bread,and several of its sensory *** is mainly due to interactions between phenolic compounds and gluten *** objective of this review is to analyze some of the most recent published works on the addition of phenolic compounds in wheat bread to identify the type of positive and negative effects that have been observed and how they can be related to the physicochemical interactions between phenolic compounds and the macromolecules that constitute the food matrix,mainly *** effect of monomeric and polymeric phenolic compounds on the strength of these interactions and on the properties of dough and bread are discussed.

关键词： condensed tannins hydrolysable tannins phenolic acids gluten food rheology food texture protein-phenolic interactions disulfide bonds non-covalent interactions

Maize seed coatings and seedling sprayings with chitosan and hydrogen peroxide:their influence on some phenological and biochemical behaviors

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2013年第2期14卷 87-96页

作者： Eva-Guadalupe LIZRRAGA-PAULíN Susana-Patricia MIRANDA-CASTRO Ernesto MORENO-mart.nez alma-Virginia LARA-SAGAHóN Irineo TORRES-PACHECO Laboratorio de Biotecnología Facultad de Estudios Superiores CuautitlánCampo 1Universidad Nacional Autónoma de MéxicoEstado de México 54740México Unidad de Investigación en Granos y Semillas Facultad de Estudios Superiores CuautitlánCentro de Asimilación TecnológicaUniversidad Nacional Autónoma de MéxicoEstado de México 54740México CA Ingeniería de Biosistemas División de Investigación y PosgradoFacultad de IngenieríaUniversidad Autónoma de QuerétaroQuerétaro 76010México

Objective： To evaluate the effect of chitosan （CH） and hydrogen peroxide （H2O） seed coatings and seedling sprinklings on two different maize varieties by measuring their phenology, the H202 presence, the catalase （CAT） activity, and the protein quantity. Methods： Seven groups of ten seeds for each maize variety were treated with CH （2% （20 g/L） and 0.2% （2 g/L）） or H2O2 （8 mmol/L） by coating, sprinkling, or both. Germination and seedling growth were measured. One month after germination, the presence of H202 in seedlings in the coated seed treatments was evaluated. Protein content and CAT activity were determined under all treatments. Results： H2O2 seed coating en- hanced the germination rate and increased seedling and stem length in the quality protein maize （QPM） variety. Seedlings had a higher emergence velocity under this treatment in both varieties. CH and H2O2 sprinklings did not have an effect on seedling phenology. Exogenous application of H2O2 promoted an increase of endogenousH2O2. OH and H2O2seedling sprinkling increased the protein content in both maize varieties, while there was no significant effect on the CAT activity of treated seeds and seedlings. Conclusions： CH and H2O2 enhance some phenological and biochemical features of maize depending on their method of application.

关键词： Zea mays Chitosan Hydrogen peroxide Phenology Catalase Protein

Lima Bean(Phaseolus lunatus)Protein Hydrolysates with ACE-I Inhibitory Activity

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Food and Nutrition Sciences 2012年第4期3卷 511-521页

作者： Luis Chel-Guerrero Mario Domínguez-Magana alma mart.nez-ayala Gloria Dávila-Ortiz David Betancur-Ancona Facultad de Ingeniería Química Universidad Autónoma de YucatánMéridaMéxico Escuela Nacional de Ciencias Biológicas Instituto Politécnico NacionalMiguel HidalgoMéxico Centro de Investigación en Biotecnología Aplicada Instituto Politécnico NacionalTlaxcalaMéxico

Several protein sources can be used to produce bioactive peptides with angiotensin I-converting enzyme (ACE) inhibittory activity. Protein concentrates from ungerminated and germinated lima bean Phaseolus lunatus seed flours were hydrolyzed with Alcalase 2.4 L or pepsin-pancreatin sequential hydrolysis, and ACE inhibitory activity measured in the different hydrolysis treatments. Protein hydrolysate production was analyzed with a 23 factorial design with four replicates of the central treatment. Evaluated factors were protein concentrate source (ungerminated seeds, PC1;germinated seeds, PC2), enzyme/substrate ratio E/S (1/50 or 1/10) and hydrolysis time (0.5 or 2.0 h for Alcalase;1 or 3 h for pepsin-pancreatin). Degree of hydrolysis (DH) was high for the Alcalase hydrolysates (24.12% 58.94%), but the pepsin-pancreatin hydrolysates exhibited the highest ACE inhibitory activity (IC50 = 0.250 0.692 mg/mL). Under the tested conditions, the hydrolysates with the highest ACE inhibitory activity were produced with sequential pepsin-pancreatin using either PC1 at 1 h hydrolysis time and a 1/10 E/S ratio or PC2 at 1 h hydrolysis time and a 1/50 E/S ratio. Lima bean protein hydrolysates prepared with Alcalase or pepsin-pancreatin are a potential ingredient in the production of physiologically functional foods with antihypertensive activity.

关键词： Lima Bean Degree of Hydrolysis ACE Inhibition Protein Hydrolysates IC50

Authors and Open Access:Effective Ways to Achieve OA in China

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图书情报工作 2005年第12期49卷 17-25页

作者： alma Swan Key Perspectives Ltd. 48 Old Coach Road Playing PlaceTruroTR3 6ETUnited Kingdom

Although there are effective methods available to authors for providing open access to their work, more than half are still not doing so and provision in China is poorer than in many other countries. There are a number of issues and concerns that dissuade authors from making their work open access: some are still unaware of the concept and of the increased visibility and impact that open access brings; many are unfamiliar with open access journals and how they work; many are uninformed about self-archiving and for some of those who are aware of the possibility of providing open access by this means, concerns about copyright and technical issues *** all these worries can be addressed with simple facts that reassure and encourage authors to adopt open access to benefit themselves,their research and their teaching. There is also a wealth of resources now available to authors that provide information and advice on open access and its effects. As institutions and research funders, both with a strong interest in maximising the visibility and impact of research they support, begin to develop formal policies on open access, models for its provision are emerging. The optimal model is a frills' variant) or by service providers who add functionality or selectivity to provide users with value-enhanced products.

关键词：中国 OA 信息资源网格技术学术材料资源共享

Constant-gain nonlinear adaptive observers revisited: an application to chemostat systems

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Frontiers of Information Technology & Electronic Engineering 2021年第1期22卷 68-78页

作者： Jorge A.TORRES Arno SONCK Sergej CELIKOVSKY alma R.DOMINGUEZ Automatic Control Department CINVESTAVMexico City 07360Mexico The Czech Academy of Sciences Institute of Information Theory and AutomationPrague 18200Czech Republic Biotechnology and Bioengineering Department CINVESTAVMexico City 07360Mexico

This study deals with constant-gain adaptive observers for nonlinear systems,for which relatively few solutions are available for some particular *** introduce an asymptotic observer of constant gain for nonlinear systems that have linear *** allows the observer design to be formulated within the linear matrix inequality paradigm provided that a strictly positive real condition bet ween the inpu t disturbance and the output is *** proposed observer is t hen applied to a large class of nonlinear chemos tat dynamical systems that are widely used in the fermentation process,cell cultures,medicine,*** fact,under standard practical assumptions,the necessary change of the chemos tat state coordinates exis ts,allowing use of the const ant-gain ***,the developed theory is illustrated by estimating pollutant concentration in a Spirulina maxima wastewater treatment facility.

关键词： Nonlinear observers Adaptive observers Coordinate change Chemos tat Pollu taut observation

The effect of fasting and body reserves on cola tolerance in 2 pit-building insect predators

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Current Zoology 2017年第3期63卷 287-294页

作者： Inon SCHARF alma DANIEL Heath Andrew MACMILLAN Noa KATZ Department of Zoology Faculty of Life Sciences Tel Aviv University POB 39040 69978 Tel Aviv Israel Department of Biology York University 4700 Keele St. Toronto Ontario Canada

Pit-building antlions and wormlions are 2 distantly-related insect species, whose larvae construct pits in loose soil to trap small arthropod prey. This convergent evolution of natural histories has led to additional similarities in their natural history and ecology, and thus, these 2 species encounter similar abiotic stress （such as periodic starvation） in their natural habitat. Here, we measured the cold tolerance of the 2 species and examined whether recent feeding or food deprivation, as well as body composition （body mass and lipid content） and condition （quantified as mass-to-size residuals） affect their cold tolerance. In contrast to other insects, in which food deprivation either enhanced or impaired cold tolerance, prolonged fasting had no effect on the cold tolerance of either species, which had similar cold tolerance. The 2 species differed, however, in how cold tolerance related to body mass and lipid content： although body mass was positively correlated with the wormlion cold tolerance, lipid content was a more reliable predictor of cold tolerance in the antlions. Cold tolerance also underwent greater change with ontogeny in wormlions than in antlions. We discuss possible reasons for this lack of effect of food deprivation on both species＇ cold tolerance, such as their high starvation tolerance （being sit-and-wait predators）.

关键词： chill coma deprivation ecophysiology fat content food hunger morphometrics Myrmeleontidae Vermileonidae.

Marine Metagenome as A Resource for Novel Enzymes

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Genomics, Proteomics & Bioinformatics 2015年第5期13卷 290-295页

作者： Amani D.alma'abadi Takashi Gojobori Katsuhiko Mineta Computational Bioscience Research Center (CBRC) King Abdullah University of Science and Technology (KAUST)

More than 99% of identified prokaryotes, including many from the marine environment, cannot be cultured in the laboratory. This lack of capability restricts our knowledge of microbial genetics and community ecology. Metagenomics, the culture-independent cloning of environmental DNAs that are isolated directly from an environmental sample, has already provided a wealth of information about the uncultured microbial world. It has also facilitated the discovery of novel bio- catalysts by allowing researchers to probe directly into a huge diversity of enzymes within natural microbial communities. Recent advances in these studies have led to a great interest in recruiting microbial enzymes for the development of environmentally-friendly industry. Although the metage- nomics approach has many limitations, it is expected to provide not only scientific insights but also economic benefits, especially in industry. This review highlights the importance of metagenomics in mining microbial lipases, as an example, by using high-throughput techniques. In addition, we dis- cuss challenges in the metagenomics as an important part of bioinformatics analysis in big data.

关键词： Microbial diversity Culture-independent studies Catalysis Lipase Biotechnology