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Safety of endoscopic retrograde cholangiopancreatography in pregnancy: Fluoroscopy time and fetal exposure, does it matter?

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World Journal of Gastrointestinal Endoscopy 2013年第4期5卷 148-153页

作者： Ioana Smith Monica Gaidhane allen goode Michel Kahaleh Department of Medicine University of Alabama Division of Gastroenterology and Hepatology Weill Cornell Medical College Radiology and Medical Imaging University of Virginia

AIM: To estimate the fetal radiation exposure using thermoluminescent dosimeters (TLD's) in pregnant patients undergoing endoscopic retrograde cholangiopancreatography (ERCP) and assess its relevance. METHODS: Data on thirty-five therapeutic ERCPs conducted in pregnant patients from 2001 to 2009 were retrieved from a prospective database. Techniques to minimize fluoroscopy time were implemented and the fluoroscopy times captured. TLD's were placed on the mother to estimate the fetal radiation exposure and the results were compared to the maximum allowed dose of radiation to the fetus [0.005 gray (Gy)]. Obstetrics consultations were obtained and the fetus was monitored before and after the ERCP. Fluoroscopy wasperformed at 75 kVp. ERCP was performed with the patients supine by dedicated biliary endoscopists performing more than 500 cases a year. RESULTS: A total of 35 pregnant patients underwent ERCP and biliary sphincterotomy (14 in first trimester, 11 in second trimester, and 10 in third trimester). Mean maternal age was 25 years (range 16-37 years) and mean gestational age was 18.9 wk (range 4-35 wk). Mean fluoroscopy time was 0.15 min (range 0-1 min). For 23 women, the estimated fetal radiation exposure was almost negligible (< 0.0001 Gy) while for 8 women, it was within the 0.0001-0.0002 Gy range. Three women had an estimated fetal radiation exposure between 0.0002 and 0.0005 Gy and 1 woman had an estimated fetal radiation exposure greater than 0.0005 Gy. Complications included 2 post-sphincterotomy bleeds, 2 post-ERCP pancreatitis, and 1 fatal acute respiratory distress syndrome. One patient developed cholecystitis 2 d after ERCP. CONCLUSION: ERCP with modified techniques is safe during pregnancy, and estimating the fetal radiation exposure from the fluoroscopy time or measuring it via TLD's is unnecessary.

关键词： Endoscopic retrograde cholangiopancreatography Pregnancy Fluoroscopy Fetal exposure Pancreaticobiliary disease

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Endoscopic Imaging of Gonads,Sex Ratio and Temperature Dependent Sex Determination in Captive Bred Juvenile Burmese Star Tortoises Geochelone platynota

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Asian Herpetological Research 2011年第4期2卷 240-244页

作者： Gerald KUCHLING Eric goode Peter PRASCHAG Chelonia Enterprises 154 Bagot RoadSubiacoWA 6008Australia School of Animal Biology the University of Western Australia35 Stirling HighwayCrawleyWA 6008Australia Turtle Conservancy 49 Bleecker StreetSuite 601New YorkNY 10012USA Behler Chelonian Center OjaiCaliforniaCA 93024USA Behler Chelonian Center

The possibility of temperature dependent sex determination makes it important to evaluate sex ratios in captive breeding programs of threatened tortoises. We assessed the sex ratio of juvenile Burmese Star Tortoises Geochelone platynota by direct observation of their gonads through an endoscope in the captive breeding program of the Behler Chelonian Center （BCC） in California. The gonads of small juvenile G. platynota are thin and elongate, and fixed to the dorsal part of body cavity, with ovaries appearing as transparent sheaths with some oocytes visible and testes appearing as small, transparent, thin, sausage-like structures with a net of fine blood vessels on the surface. With growth, ovaries expand and masses of pre-vitellogenic follicles appear on the surface. Testes are transparent in small juveniles and, with growth, turn pinkish-white and then yellowish, with tubuli structures visible through a thin, transparent theca containing a network of fine blood vessels. Egg incubation temperatures were not rigorously monitored, but a temperature of 28.9 ℃ produced a heavily male biased sex ratio whereas a temperature of 30 ℃ produced a balanced sex ratio. This suggests that G. platynota has temperature dependent sex determination.

关键词： Geocheloneplatynota Testudinidae incubation temperature testis ovary

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Disturbance history,species diversity,and structural complexity of a temperate deciduous forest

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Journal of Forestry Research 2020年第2期31卷 397-414页

作者： Jonathan D.goode Carson R.Barefoot Justin L.Hart Daniel C.Dey Department of Geography University of AlabamaTuscaloosaAL 35487USA Northern Research Station USDA Forest ServiceColumbiaMO 65211USA

Stand structural complexity enhancement is an increasingly popular management objective,especially on public *** stand structures are hypothesized to support a relatively high degree of native forest diversity and be more resistant and resilient to *** structures are characterized by the presence of deadwood and heterogeneity of tree-size classes and tree *** little is known about how discrete disturbance events affect structural complexity and compositional diversity in Quercus-dominated stands at fine spatial scales(***).We established 200.05 ha fixed-radius plots on the Sipsey Wilderness of William *** National Forest in northern Alabama to quantify woody plant species composition and *** were mapped on each plot to quantify overstory structural complexity and compositional *** extracted two cores from all canopy Quercus spp.C 5 cm diameter at breast height to quantify age,recruitment pulses,and reconstruct canopy disturbance *** species diversity in the sampled area was 1.75 for trees,2.08 for saplings,and 1.69 for *** alba had the greatest basal area,and Ostrya virginiana had the highest *** stand exhibited a reverse J-shaped distribution with a q-factor of *** oldest Quercus dated to 1795,and the largest recruitment pulse occurred in the *** mean return interval for intermediateseverity disturbance was 38 *** we documented no relationships between disturbance frequency and compositional diversity at the neighborhood scale(0.05 ha),less frequent disturbance was associated with higher structural complexity(r^2=0.258,p=0.026)at the neighborhood *** suggest that localized disturbance increases species diversity and structural complexity,but these processes are manifest at the stand level and not at the neighborhood *** conclude that the spatial variability(***,shape,orientation,microsite conditions)is likel

关键词： Canopy gap Quercus(oak) Stand development Succession

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Mortality of a Wild King Cobra, Ophiophagus hannah Cantor, 1836(Serpentes: Elapidae) from Northeast Thailand after Ingesting a Plastic Bag

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Asian Herpetological Research 2014年第4期5卷 284-286页

作者： Colin Thomas STRINE Inês SILVA Matthew CRANE Bartosz NADOLSKI Taksin ARTCHAWAKOM Matt goode Pongthep SUWANWAREE Suranaree University of Technology Sakaerat Environmental Research Station School of Natural Resources and Environment University of Arizona

Wild King Cobras, Ophiophagus hannah, are known to prey almost exclusively on snakes. We observed opportunistic ingestion of a plastic bag by a radio-tracked adult male O. hannah, which was detrimental to the health of the individual and likely lead to its death. Our observation demonstrates that improper disposal of food and plastic waste can be a threat to snakes, highlighting the need to maintain a waste-free environment, especially in areas inhabited by vulnerable species.

关键词： Garbage Sakaerat Snake Waste King Cobra Ophiophagus hannah

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英国城市自然保护

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生态学报 1990年第1期10卷 96-108页

作者： D.A.goode 路力伦敦生态学联合会

1.该文依据城市生态系统的最新研究成果以及规划、景观设计和自然保护社会学研究方面的新进展,评述了英国城市自然保护方面的发展。 2.从1980年以来,由于生态学家的参与,这门学科发展得非常迅速。在规划和土地管理方面,很多地方政府执... 详细信息

1.该文依据城市生态系统的最新研究成果以及规划、景观设计和自然保护社会学研究方面的新进展,评述了英国城市自然保护方面的发展。 2.从1980年以来,由于生态学家的参与,这门学科发展得非常迅速。在规划和土地管理方面,很多地方政府执行了城市自然保护计划,以伦敦为例,笔者描述了这种新的的发展趋势。 3.城市区域的自然保护与传统的自然保护方法在一些方面有所不同。前者侧重于研究城市野生生物对当地居民的价值和益处,而不强调稀有种和濒危物种及它们的生境。因此,评价标准既包括生物学方面的因素,也包括社会学指标。 4.有价值的生境既包括早已存在的半自然状态的生境,也可以包括那些近期在废弃土地人工基层上发展起来的生境,退化土地的改良以及新生境的产生是至关重要的。 5.近年来,在城市景观设计中生态学的方法被越来越广泛地利用。目前,已建立了一些建造生境的技术,但是由于习惯势力的原因,这些技术得不到大规模的应用。 6.讨论了地方居民在城市野生生物计划中的作用。研究成果显示了这些计划的社会效益,地方居民的参与对于计划成功有决定性意义。 7.城市自然保护需要得到各方面专家的参与,包括生态学家、规划人员,景观设计人员、社会学家以及志愿者组织和城镇居民等。 8.

关键词：英国城市自然保护城市生态学

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Development of a Rapid Risk and Impact Assessment Tool to Enhance Response to Environmental Emergencies in the Early Stages of a Disaster: A Tool Developed by the European Multiple Environmental Threats Emergency NETwork (EMETNET) Project

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International Journal of Disaster Risk Science 2021年第4期12卷 528-539页

作者： Emma-Jane goode Eirian Thomas Owen Landeg Raquel Duarte-Davidson Lisbeth Hall Jolanda Roelofs Sjors Schulpen Arnout De Bruin Elisabeth Wigenstam Birgitta Liljedahl Annica Waleij Louise Simonsson Ann Göransson Nyberg Centre for Radiation Chemicals and EnvironmentPublic Health England(PHE)Harwell CampusDidcotOX11 ORQUK Centre for Environmental Safety and Security National Institute for Public Health and the Environment(RIVM)Bilthoven3721 MAThe Netherlands Division of CBRN Defence and Security Swedish Defense Research Agency(FOI)90182UmeåSweden

Every year,numerous environmental disasters and emergencies occur across the globe with far-reaching impacts on human health and the *** ability to rapidly assess an environmental emergency to mitigate potential risks and impacts is ***,collating the necessary evidence in the early stages of an emergency to conduct a robust risk assessment is a major *** article presents a methodology developed to help assess the risks and impacts during the early stages of such incidents,primarily to support the European Union Civil Protection Mechanism but also the wider global community in the response to environmental *** online rapid risk and impact assessment tool has also been developed to promote enhanced collaboration between experts who are working remotely,considering the impact of a disaster on the environment and public health in the short,medium,and long *** methodology developed can support the appropriate selection of experts and assets to be deployed to affected regions to ensure that potential public health and environmental risks and impacts are mitigated whenever *** methodology will aid defensible decision making,communication,planning,and risk management,and presents a harmonized understanding of the associated impacts of an environmental emergency.

关键词： Civil protection Environmental emergencies Impact assessment Risk assessment Systematic expert judgment

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无人机将改变勘探填图方式

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矿产勘查 2018年第1期9卷 173-175页

作者： Keith goode Eagle Research Advisory Pty Ltd Cremorne NSWAustralia 2090

最近两年间,澳大利亚从事矿产勘查的很多人都在一些会展上观看过譬如Carbine（CRB）公司播放的无人机拍摄的矿山和勘探区视频。但在2017年6月中旬,笔者见到了无人机工作的进阶版,也即Alto Metals公司利用无人机在西澳洲Sandstone金矿田... 详细信息

最近两年间,澳大利亚从事矿产勘查的很多人都在一些会展上观看过譬如Carbine（CRB）公司播放的无人机拍摄的矿山和勘探区视频。但在2017年6月中旬,笔者见到了无人机工作的进阶版,也即Alto Metals公司利用无人机在西澳洲Sandstone金矿田（几乎全部归Alto Metals公司所有）的航拍成果。

关键词：无人机远景区

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The Aryl Hydrocarbon Receptor: A Target for Breast Cancer Therapy

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Journal of Cancer Therapy 2013年第7期4卷 1177-1186页

作者： Joann B. Powell Gennifer D. goode Sakina E. Eltom Department of Biochemistry & Cancer Biology Meharry Medical College Nashville USA. Department of Biological Sciences & Center for Cancer Research and Therapeutic Development Clark Atlanta University Atlanta USA

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that regulates a battery of genes in response to exposure to a broad class of environmental poly aromatic hydrocarbons (PAH). AhR is historically characterized for its role in mediating the toxicity and adaptive responses to these chemicals, however mounting evidence has established a role for it in ligand-independent physiological processes and pathological conditions, including cancer. The AhR is overexpressed and constitutively activated in advanced breast cancer cases and was shown to drive the progression of breast cancer. In this article we will review the current state of knowledge on the possible role of AhR in breast cancer and how it will be exploited in targeting AhR for breast cancer therapy.

关键词： Aryl Hydrocarbon Receptor Therapeutic Targeting Breast Cancer Progression Chemosensitization

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Magnet rare earth production must double in 10 years——Where will production come from?

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China Rare Earth Information 2022年第4期28卷 12-24页

作者： John R.goode ARSM FCIMMFAUsIMMPEng

Author:When I first heard that statement about future production,I asked myself"Where will production come from?".Additionally,the western world seeks to establish supply chains which are less reliant on China.I have worked in the rare earth field for much of my life and understand the difficulty of developing rare earth extraction and separation *** news that rare earth production must double in the next 10 years seemed incredible and promoted the investigation that led to this article.

关键词：稀土产品 statement rare

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可调节式人工砧骨的颞骨实验研究

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耳鼻咽喉（头颈外科） 2002年第3期9卷 164-166页

作者：赵守琴 goode RL 首都医科大学附属北京同仁医院耳鼻咽喉-头颈外科 100730 美国斯坦福大学医学中心

目的 :对中耳听力重建手术来说 ,合适的人工听骨张力是至关重要的 ,而刚性人工听骨的张力与其长度直接相关。本文目的为探讨人工听骨的长度发生细微变化 (即听骨链的张力发生微小变化 )时 ,中耳的声音传输特点。方法 :7个成人颞骨冰冻... 详细信息

目的 :对中耳听力重建手术来说 ,合适的人工听骨张力是至关重要的 ,而刚性人工听骨的张力与其长度直接相关。本文目的为探讨人工听骨的长度发生细微变化 (即听骨链的张力发生微小变化 )时 ,中耳的声音传输特点。方法 :7个成人颞骨冰冻标本被采用 ,将一可调节长度钛质人工砧骨植入到颞骨标本中 ,用多普勒激光测振系统 (HL V- 10 0 0型 ,Polytec,PI,Costa Mesa,CA)测量镫骨底板的位移 ,声刺激为 0 .1～ 10 k Hz间的 4 0 6个纯音 ,鼓膜表面的声刺激强度为80 d B SPL。首先测量听骨链完整时镫骨底板的位移 (即基线 ) ,然后摘除砧骨 ,将人工砧骨植入到镫骨头与槌骨柄尖端之间。调节砧骨的长度 ,使其处于最佳长度状态 (即最合适张力 )以及在此基础上分别增加 0 .2 mm和 0 .4 mm,再分别测量这三种状态时镫骨底板的位移。结果 :当人工砧骨处于最佳长度时 ,与听骨链完整时的基线相比 ,在 1.0 k Hz以下声音传输相差 0 .2 d B;1.0～ 3.0 k Hz之间 ,平均听力降低 1.7d B;3.0 k Hz以上 ,声音传输比基线好。当人工砧骨的长度增加0 .2 mm(一个刻度 )时 ,与基线相比 ,1.0 k Hz以下 ,平均降低 6 .0 d B,1.0 k Hz以上 ,平均降低 3.0 d B。当人工砧骨的长度再增加 0 .2 mm(共增加 2个刻度 ) ,与基线相比 ,1.0 k

关键词：可调节式人工砧骨假体颞骨多普勒效应

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