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Machine Learning Models for Heterogenous Network Security Anomaly Detection

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Journal of Computer and Communications 2024年第6期12卷 38-58页

作者： Mercy Diligence Ogah Joe Essien martin Ogharandukun Monday Abdullahi Department of Computer Science Veritas University Abuja Nigeria Department of Pure and Applied Physics Veritas University Abuja Nigeria Department of Computer Science Air Force Institute of Technology Kaduna Nigeria

The increasing amount and intricacy of network traffic in the modern digital era have worsened the difficulty of identifying abnormal behaviours that may indicate potential security breaches or operational interruptions. Conventional detection approaches face challenges in keeping up with the ever-changing strategies of cyber-attacks, resulting in heightened susceptibility and significant harm to network infrastructures. In order to tackle this urgent issue, this project focused on developing an effective anomaly detection system that utilizes Machine Learning technology. The suggested model utilizes contemporary machine learning algorithms and frameworks to autonomously detect deviations from typical network behaviour. It promptly identifies anomalous activities that may indicate security breaches or performance difficulties. The solution entails a multi-faceted approach encompassing data collection, preprocessing, feature engineering, model training, and evaluation. By utilizing machine learning methods, the model is trained on a wide range of datasets that include both regular and abnormal network traffic patterns. This training ensures that the model can adapt to numerous scenarios. The main priority is to ensure that the system is functional and efficient, with a particular emphasis on reducing false positives to avoid unwanted alerts. Additionally, efforts are directed on improving anomaly detection accuracy so that the model can consistently distinguish between potentially harmful and benign activity. This project aims to greatly strengthen network security by addressing emerging cyber threats and improving their resilience and reliability.

关键词： Cyber-Security Network Anomaly Detection Machine Learning Random Forest Decision Tree Gaussian Naive Bayes

Optical magnetic field enhancement using ultrafast azimuthally polarized laser beams and tailored metallic nanoantennas

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Photonics Research 2024年第5期12卷 1078-1092页

作者： RODRIGO martin-HERNANDEZ LORENZ GRUNEWALD LUIS SANCHEZ-TEJERINA LUIS PLAJA ENRIQUECONEJERO JARQUE CARLOS HERNANDEZ-GARCIA SEBASTIAN MAI Grupo de Investigacion en Aplicaciones del Laser y Fotonica Departamento de Fisica AplicadaUniversidad de SalamancaE-37008 SalamancaSpain Unidad de Excelencia en Luz y Materia Estructuradas(LUMES) Universidad de SalamancaE-37008 SalamancaSpain Institute of Theoretical Chemistry Faculty of ChemistryUniversity of Vienna1090 ViennaAustria Vienna Doctoral School in Chemistry(DoSChem) Faculty of ChemistryUniversity of Vienna1090 ViennaAustria Departamento de Electricidad y Electrónica Universidad de Valladolid47011 ValladolidSpain

*** *** thank Valentina Shumakova,Elizaveta Gangrskaia,Alessandra Bellissimo,Audrius Pugzlys,and Andrius Baltu?ka for fruitful discussions and computational support by the Vienna Scientific Cluster(VSC 4).The authors thankfully acknowledge the computer resources at MareNostrum and SCAYLE,and the technical support provided by Barcelona Supercomputing Center(RES-FI-2022-3-0041).R.M.-H.,L.S.-T.,L.P.,E.C.J.,and C.H.-*** funding from the European Research Council(ERC)under the European Union’s Horizon 2020 research and innovation program(Grant Agreement No.851201)and support from Ministerio de Ciencia e Innovación(PID2022-142340NB-I00,PID2019-106910GB-I00).This research was funded in whole or in part by the Austrian Science Fund(FWF)(10.55776/ZK91).For open access purposes,the author has applied a CC BY public copyright license to any author accepted manuscript version arising from this submission.

关键词： metallic polarized discussions

Integration of traditional,complementary,and alternative medicine with modern biomedicine:the scientization,evidence,and challenges for integration of traditional Chinese medicine

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Acupuncture and Herbal Medicine 2024年第1期4卷 68-78页

作者： Zihao Zhang Raorao Li Yu Chen Hui Yang martin Fitzgerald Qiaochu Wang Ziwen Xu Nanxi Huang Dajun Lu Lu Luo Georgetown University Medical Center Washington DCUSA Institute of Chinese Materia Medica China Academy of Chinese Medical SciencesBeijingChina Institute of Acupuncture and Moxibustion China Academy of Chinese Medical SciencesBeijingChina The First Clinical Medical College Guizhou University of Traditional Chinese MedicineGuiyangChina Ashdale Clinic Half Moon LaneSouth Douglas RoadCorkIreland

Traditional medicine has garnered significant global recognition,with an estimated 80%of the global population using ***,it is essential to fully understand the integration of traditional medicines into current healthcare *** review aims to provide a comprehensive overview of the standard process to modernize traditional medicine scientifically in the context of modern biomedicine,further termed here as“scientization”.Specifically,we aim to summarize the advancements made in understanding the efficacy,effectiveness,and underlying mechanisms of herbal *** also examined the transition from experience-to evidence-based medicine during ***,we explore the development of universal safety and quality control ***,we discuss international trade and export markets for Chinese medical *** development and integration of traditional medicine have allowed it to further improve human health,resulting in a more comprehensive health solution for the global population.

关键词： Acupuncture Conventional medicine Herbal medicine Modernization Scientization Traditional Chinese medicine

Cold-Induced Reprogramming of Subcutaneous White Adipose Tissue Assessed by Single-Cell and Single-Nucleus RNA Sequencing

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Research 2024年第1期2023卷 763-778页

作者： Qing Liu Qiaoyun Long Jiayu Zhao Wenjie Wu Zexin Lin Wei Sun Ping Gu Tuo Deng Kerry martin Loomes Donghai Wu Alice P.S.Kong Jingying Zhou Alfred S.Cheng Hannah Xiaoyan Hui School of Biomedical Sciences The Chinese University of Hong KongHong KongChina Department of Pharmacology and Pharmacy The University of Hong KongHong KongChina Guangzhou Institute of Biomedicine and Health Chinese Academy of SciencesGuangzhouChina China-New Zealand Joint Laboratory on Biomedicine and Health Chinese Academy of SciencesGuangzhouChina Department of Endocrinology Jinling HospitalNanjing UniversitySchool of MedicineNanjingChina National Clinical Research Center for Metabolic Diseases and Department of Metabolism and EndocrinologyThe Second Xiangya Hospital of Central South UniversityChangshaChina Key Laboratory of Diabetes Immunology Ministry of Educationand Metabolic Syndrome Research CenterThe Second Xiangya Hospital of Central South UniversityChangshaChina Clinical Immunology Center The Second Xiangya Hospital of Central South UniversityChangshaChina School of Biological Sciences and Maurice Wilkins Centre University of AucklandAucklandNew Zealand Department of Medicine and Therapeutics The Chinese University of Hong KongHong KongChina Hong Kong Institute of Diabetes and Obesity The Chinese University of Hong KongPrince of Wales HospitalShatinHong KongChina Li Ka Shing Institute of Health Sciences The Chinese University of Hong KongPrince of Wales HospitalShatinHong KongChina

Adipose browning has demonstrated therapeutic potentials in several ***,by conducting transcriptomic profiling at the single-cell and single-nucleus resolution,we reconstituted the cellular atlas in mouse inguinal subcutaneous white adipose tissue(iWAT)at thermoneutrality or chronic cold *** major nonimmune cells within the iWAT,including adipose stem and progenitor cells(ASPCs),mature adipocytes,endothelial cells,Schwann cells,and smooth muscle cells,were recovered,allowing us to uncover an overall and detailed blueprint for transcriptomes and intercellular cross-talks and the dynamics during white adipose tissue brown *** findings also unravel the existence of subpopulations in mature adipocytes,ASPCs,and endothelial cells,as well as new insights on their interconversion and reprogramming in response to *** adipocyte subpopulation competent of major histocompatibility complex class Ⅱ(MHCⅡ)antigen presentation is ***,a subcluster of ASPC with CD74 expression was identified as the precursor of this MHCⅡ^(+)*** adipocytes are transdifferented from preexisting lipid generating adipocytes,which exhibit developmental trajectory from de novo differentiation of amphiregulin cells(Aregs).Two distinct immune-like endothelial subpopulations are present in iWAT and are responsive to *** data reveal fundamental changes during cold-evoked adipose browning.

关键词： evoked programming generating

Message from the Best Paper Award Committee

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Computational Visual Media 2024年第3期10卷 397-397页

作者： Ming C.Lin Baoquan Chen Ying He Wenping Wang Kun Zhou Ralph martin Associate Editor-in-Chief University of Maryland at College Park USA 不详

Following the success of the past eight years,Tsinghua University Press has continued to sponsor an annual award for the best papers published in Computational Visual *** papers in 2023 from Computational Visual Media were recommended by Associate Editors as candidate papers for the Best Paper *** Editors-in-Chief Ming *** and Ralph martin led the Best Paper Award Committee to select the Best *** careful deliberation,the following paper was chosen with the unanimous consensus as the winner.

关键词： Visual Award Message

Evaluation of Four Anthropogenic Activity Impacts on Heavy Metal Quality of the Kumba River in the South West Region of Cameroon

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Journal of Water Resource and Protection 2024年第5期16卷 361-380页

作者： martin Keghe Nkobe Barthelemy Ndongo Kanouo Boris Merlain Djousse Salomon Nyasse Institute of Agricultural Research for Development (IRAD) Yaound&#233 Cameroon Faculty of Agronomy and Agricultural Sciences (FASA) University of Dschang Dschang Cameroon

Anthropogenic activities have contributed to pollution of water bodies through deposition of diverse pollutants amongst which are heavy metals. These pollutants, which at times are above the maximum concentration levels recommended, are detrimental to the quality of the water, soil and crops (plant) with subsequent human health risks. The objective of the work was to evaluate the impacts of human-based activities on the heavy metal properties of surface water with focus on the Kumba River basin. Field observations, interviews, field measurements and laboratory analyses of different water samples enabled us to collect the different data. The results show four main human-based activities within the river basin (agriculture, livestock production, domestic waste disposal and carwash activities) that pollute surface water. Approximately 20.61 tons of nitrogen and phosphorus from agricultural activities, 156.48 tons of animal wastes, 2517.5 tons of domestic wastes and 1.52 tons of detergent from carwash activities were deposited into the river each year. A highly significant difference at 1% was observed between the upstream and downstream heavy metal loads in four of the five heavy metals tested except for copper that was not significant. Lead concentrations were highest in all the activities with an average of 2.4 mg∙L−1 representing 57.81%, followed by zinc with 1.596 mg∙L−1 (38.45%) and manganese with 0.155 mg∙L−1 (3.74%) for the different anthropogenic activities thus indicating that these activities highly lead to pollution of the Kumba River water. The level of zinc and manganese was significantly influenced at ρ 005 by anthropogenic activities though generally the variations were in the order: carwash (3.196 mg∙L−1) −1) −1) −1) r

关键词： Metal Properties Human-Based Activities Kumba River Basin Surface Water

Fe_(3)O_(4)对黄铜矿在酸性硫酸铁溶液中铜溶解氧化还原反应的影响

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Transactions of Nonferrous Metals Society of China 2024年第6期34卷 1965-1975页

作者： Kolela J NYEMBWE Elvis FOSSO-KANKEU Frans WAANDERS martin MKANDAWIRE Didier K NYEMBWE Bhekie B MAMBA Water Pollution Monitoring and Remediation Initiatives Research Group School of Chemical and Minerals EngineeringFaculty of EngineeringNorth-West UniversityPotchefstroomSouth Africa Department of Mining Engineering College of Science Engineering and TechnologyUniversity of South AfricaFlorida Science CampusJohannesburgSouth Africa Department of Metallurgy Faculty of Engineering and Built EnvironmentUniversity of JohannesburgDoornfonteinJohannesburgSouth Africa Department of Chemistry School of Science and TechnologyCape Breton UniversityCanada School of Mining Metallurgy and Chemical EngineeringFaculty of Engineering and the Built EnvironmentUniversity of JohannesburgJohannesburgSouth Africa Institute for Nanotechnology and Water Sustainability College of Science Engineering and TechnologyUniversity of South AfricaFlorida Science CampusJohannesburgSouth Africa

由于钝化层的形成,黄铜矿(CuFeS_(2))在氧化条件下浸出通常具有溶解速率缓慢的特点。为了将黄铜矿浸出过程中的钝化效应降至最低并提高铜的回收率,研究了CuFeS_(2)在不同pH值(1.0、1.5和1.8)和温度(25和50℃)条件下浸出时,向Fe_(2)(SO_(... 详细信息

由于钝化层的形成,黄铜矿(CuFeS_(2))在氧化条件下浸出通常具有溶解速率缓慢的特点。为了将黄铜矿浸出过程中的钝化效应降至最低并提高铜的回收率,研究了CuFeS_(2)在不同pH值(1.0、1.5和1.8)和温度(25和50℃)条件下浸出时,向Fe_(2)(SO_(4))_(3)−H_(2)SO_(4)浸出剂中添加磁铁矿(Fe_(3)O_(4))对铜溶解速率的影响。结果表明,溶液pH值、电位和温度在溶解过程中起着关键作用。在pH 1.8、50℃和400 mV的条件下,Fe_(3)O_(4)−CuFeS_(2)混合体系中铜的回收率达到最大值(70%),而未添加Fe_(3)O_(4)时,CuFeS_(2)中铜的回收率较低(48%)。添加Fe_(3)O_(4)有助于维持较高的氧化还原值。添加Fe_(3)O_(4)还使活化能从79.04 kJ/mol降低到53.69 kJ/mol。这表明,当Fe_(3)O_(4)存在时,由于形成了更易溶解的中间体斑铜矿(Cu_(5)FeS_(4))和辉铜矿(Cu_(2)S),CuFeS_(2)更易被氧化。两种溶解过程都受到矿物表面的化学控制。此外,对浸出残渣的矿物学分析表明,当无Fe_(3)O_(4)存在时,作为表面钝化物的黄钾铁矾浓度较高。因此,添加Fe_(3)O_(4)减少了钝化层的形成,提升了铜的回收率。

关键词：黄铜矿溶解磁铁矿电偶钝化

Embracing different languages and local differences:Coconstructive patient simulation strengthens host countries’clinical training in psychiatry

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World Journal of Psychiatry 2024年第1期14卷 111-118页

作者： Şafak ErayÇamlı Büşra Ece Yavuz Meliha Feyza Gök Idil Yazgan Yanki Yazgan Ayelet Brand-Gothelf Doron Gothelf Doron Amsalem Andrés martin Department of Child and Adolescent Psychiatry Bursa UludağUniversity Faculty of MedicineBursa 16059 Turkey Yale University School of Medicine New HavenCT 06510United States Güzel Günler Clinic Beşiktaş/İstanbul 34335 Turkey Child Study Center Yale School of MedicineNew HavenCT 06520United States The Feinberg Child Study Center Schneider Children's Medical Center of IsraelTel Aviv UniversityPetach Tikvah 4920235Israel The Child Psychiatry Division Edmond and Lily Safra Children’s HospitalSheba Medical CenterTel HashomerRamat Gan 52561Israel Faculty of Medicine and Sagol School of Neuroscience Tel Aviv UniversityTel Aviv 6997801Israel Department of Psychiatry Columbia University Vagelos College of Physicians and SurgeonsNew YorkNY 10032United States

BACKGROUND Global education in psychiatry is heavily influenced by knowledge from Western,high-income countries,which obscures local voices and *** To adapt a human simulation model to psychiatric education in a context that is specific to local languages and *** We conducted an observational study consisting of six human simulation sessions with standardized patients from two host countries,speaking their native languages,and following an adaptation of the co-constructive patient simulation(CCPS)*** local faculty became increasingly familiar with the CCPS approach,they took on the role of facilitators—in their country’s native *** Fifty-three learners participated:19 child and adolescent psychiatry trainees and 3 faculty members in Türkiye(as a group that met online during 3 consecutive months);and 24 trainees and 7 faculty in Israel(divided into 3 groups,in parallel in-person sessions during a single training day).Each of the six cases reflected local realities and clinical challenges,and was associated with specific learning goals identified by each case-writing *** Human simulation has not been fully incorporated into psychiatric education:The creation of immersive clinical experiences and the strengthening of reflective practice are two areas ripe for *** adaptations of CCPS can also strengthen local and regional networks and psychiatric communities of ***,the model can help question and press against hegemonies in psychiatric training that overshadow local expertise.

关键词： Human simulation Standardized patients Medical education Psychiatric education Capacity building Local languages

Movement analysis in the diagnosis and management of Parkinson’s disease

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Neural Regeneration Research 2025年第2期20卷 485-486页

作者： Johannes Burtscher Nicolas Bourdillon Jules MJanssen Daalen Aurélien Patoz Julien FBally martin Kopp Davide Malatesta Bastiaan RBloem Institute of Sport Sciences University of LausanneLausanneSwitzerland Radboud University Medical Center Department of NeurologyDonders Institute for BrainCognition and BehaviorCenter of Expertise for Parkinson and Movement DisordersNijmegenThe Netherlands Radboud University Medical Center Department of Medical BioSciencesNijmegenThe Netherlands Research and Development Department Volodalen Swiss Sport LabAigleSwitzerland Service of Neurology Department of Clinical NeurosciencesLausanne University Hospital(CHUV)and University of Lausanne(UNIL)LausanneSwitzerland Department of Sport Science University of InnsbruckInnsbruckAustria

Challenges in the diagnosis and treatment of Parkinson’s disease:Parkinson’s disease(PD)is an increasingly prevalent neurodegenerative disease,at first sight primarily characterized by motor symptoms,although non-motor symptoms also constitute a major part of the overall ***,this disease cannot be diagnosed reliably until a large part of the vulnerable dopaminergic neurons has been irretrievably lost,and the disease progresses *** biological criteria for PD have been proposed recently and might eventually improve early diagnosis,but they require further validation,and their use will initially be restricted to a research environment(Darweesh et al.,2024).

关键词： diagnosis Clinical eventually