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初中生 2021年第33期 51-53页

作者： Scott paterson 朱迪(编译) 不详

家境贫寒的西蒙和佩德罗兄弟俩都梦想着有一天能成为工程师。他们商定,一个人留在当地的矿井工作,为自己的兄弟支付上大学的费用;之后,完成学业的孩子再来资助在矿井工作的兄弟上大学。但,一场事故改变了他们的计划。他们的梦想还能实现吗?

关键词：兄弟俩佩德罗工程师美好未来梦想资助完成学业

RFLP mapping and race specificity of bacterial blight resistance genes (QTLs) in rice

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Science China(Life Sciences) 1998年第5期41卷 542-547页

作者：罗利军梅捍卫赵新华钟代彬王一平余新桥应存山 Z.K.Li A.H.paterson D.L.Wang R.E.Tabien L.Zhu J.W.Stansel China National Rice Research Institute Hangzhou China Texas A & M University College Station USA

By using a set of 315 recombinant inbred lines (RILs) from the cross Lemont (japonica)×Teqing (indica) and a complete linkage map with 186 well distributed RFLP markers and 3 morphological markers, a major gene (Xa4) and 10 QTLs and 9 pairs of epistasis loci conferring horizontal resistance to three strains of \%Xanthomonas oryza\% pv \%oryza (Xoo)\% were mapped. The Teqing allele at Xa4 on chromosome 11 acts as a dominant resistant gene against pathogen race CR4 and CX08, but as an additive QTL with a significantly (47%) reduced effect \{against the\} virulent strain, CR6. The major gene Xa4 exhibited stronger degree of race specificity. Most QTLs showed consistent levels of resistance against all three \%Xoo\% strains. The results suggest that a high level durable resistance to \%Xoo\% may be achieved by cumulative effects of multiple QTL.

关键词： bacterial blight RFLP QTL race specificity.

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勇敢的跳跃

初中生 2021年第27期 96-99页

作者： Scott paterson Reya(编译) 不详

原本站在"跳台"上因为恐高而犹豫迟疑的主人公,在看到小伙伴遇险后,放下恐惧,果敢地跳入水中救起同伴。起跳的那一刻,他战胜了恐惧,也战胜了自我。我有些恐高。虽然我可以登上一座高楼或一架飞机,但如果从悬崖边或树上往下看,我就会觉... 详细信息

原本站在"跳台"上因为恐高而犹豫迟疑的主人公,在看到小伙伴遇险后,放下恐惧,果敢地跳入水中救起同伴。起跳的那一刻,他战胜了恐惧,也战胜了自我。我有些恐高。虽然我可以登上一座高楼或一架飞机,但如果从悬崖边或树上往下看,我就会觉得头晕。之所以提到这一点,是因为它与我要讲述的这个发生在几年前的故事有很大关系。那时,我和朋友们常常在湖边玩耍。

关键词：悬崖边小伙伴恐惧

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缺血时三维心室外膜Map多重分形的变化

科学通报 2005年第22期50卷 2479-2483页

作者：陈颖 Martyn P.Nash 宁新宝王业琳 David J.paterson 王俊南京大学电子科学与工程系近代声学国家重点实验室生物医学电子工程研究所 Engineering Scienceand Bioengineering Institute University of AucklandPrivate Bag 92019NZ Laboratory of Physiology University of OxfordParks RoadOxford OX13PTUK

对三维心室外膜Map的电压信号时间序列进行了研究,分析了一个短时的缺血-再灌注动物模型,研究心肌缺血与心室外膜电位多重分形特性变化的关系.提出了一个新的多重分形奇异谱的分析参数SARD,来着重刻画系统的多重分形随时间的变化.通过... 详细信息

对三维心室外膜Map的电压信号时间序列进行了研究,分析了一个短时的缺血-再灌注动物模型,研究心肌缺血与心室外膜电位多重分形特性变化的关系.提出了一个新的多重分形奇异谱的分析参数SARD,来着重刻画系统的多重分形随时间的变化.通过对比心外膜心肌激活序列等时图与心外膜的三维SARD图,发现心肌缺血对于心外膜电位的多重分形特性的变化有显著的影响,SARD值在心室外膜上的分布与缺血部位有密切的联系.

关键词：非线性动力学多重分形心脏心室外膜Map 心肌缺血

Thellier-type paleointensity data from multidomain specimens

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Thellier-type paleointensity data from multidomain specimens

中国科学院地质与地球物理研究所2015年度（第15届）学术年会

作者： Greig A.paterson Andrew J.Biggin Emma Hodgson Mimi J.Hill Key Laboratory of Earth and Planetary Physics Institute of Geology and Geophysics Chinese Academy of Sciences

Identifying and excluding inaccurate paleointensity estimates that can arise from the effects of multidomain(MD) particles remains a key challenge for paleointensity studies. Here we approach this problem by incorporating realistic experimental noise into a phenomenological MD model, systematically exploring the parameter space of paleointensity experiments(the choice of protocol, laboratory field strengths and directions), applying optimization algorithms to the model predictions, and testing these against experimental datasets. The results allow us to conclude that:(1) In some cases, applying the lab field in a direction [60 from the NRM direction and with a magnitude～2 times larger than the ancient field may help to produce more linear and accurate Arai plots by allowing partial thermoremanent magnetization(p TRM) tails to compensate from excess natural remanent magnetization(NRM) loss, the mechanism behind typical MD Arai plot curvature.(2) The recently proposed FRAC criterion is consistently better at isolating accurate results than the traditionally used f parameter and should ideally have minimum values of 0.65, 0.45, 0.65, and 0.55 for the Thellier, Coe, Aitken, and IZZI protocols, respectively.(3) Newly developed sets of selection criteria(MC-CRIT) should maximize the likelihood of accepting accurate estimates from a suite of specimens influenced by MD behavior. The models, methods, and data presented here provide the means to objectively define data selection and demonstrate the effectiveness of a given set of criteria. Such approaches are vital, if we wish to remove the arbitrariness that hinders the identification of reliable paleointensity data.

关键词： Paleointensity Archeointensity Multidomain Non-ideal behavior

来源： cnki会议 cnki会议评论

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阿片受体的分型

国际药学研究杂志 1984年第5期 284-288页

作者： paterson S J ,金文桥

研究阿片生物碱和阿片肽与阿片受体识别位点(Recognition site)相互作用的特点是了解它们作用模式最重要的进展之一。这种受体由识别位点与作用因子两者构成,药物与识别位点结合,作用因子则传递结合信息到最终导致生物效应的生化环节。... 详细信息

研究阿片生物碱和阿片肽与阿片受体识别位点(Recognition site)相互作用的特点是了解它们作用模式最重要的进展之一。这种受体由识别位点与作用因子两者构成,药物与识别位点结合,作用因子则传递结合信息到最终导致生物效应的生化环节。为了探索结合位点和药理效应之间的一些可能关系,迄今已很好地

关键词：结合位点亲和性拮抗剂豚鼠回肠阿片受体吗啡阿片大鼠脑输精管男生殖器受体亚型药理实验化合物温育脑匀浆结合量 EKC 配体结合拮抗活性

加利福尼亚洲Sierra Nevada中部西变质带地体的区域构造和应变分析

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世界地质 1990年第4期9卷 46-70页

作者： S.R.paterson 潘云泽

Sierra Nevada西变质带225个全应变样品的比较表明,应变类型与强度取决于岩石类型。杂砂岩和碎屑支撑砾岩应变最小,而强应变则出现于火山砾凝灰岩、含砾泥灰岩和板岩中。大的火山岩带为面型应变,而其附近的板岩和杂砂岩序列则表现为压... 详细信息

Sierra Nevada西变质带225个全应变样品的比较表明,应变类型与强度取决于岩石类型。杂砂岩和碎屑支撑砾岩应变最小,而强应变则出现于火山砾凝灰岩、含砾泥灰岩和板岩中。大的火山岩带为面型应变,而其附近的板岩和杂砂岩序列则表现为压扁型应变,表明在板岩中有40％～65％的体积损失,杂砂岩中有0～26％的体积损失,火山砾凝灰岩中体积损失为11％。不同岩石类型之间体积损失和应变的差异要求在大多数岩性界面上存在总应变的不连续。在西变质带范围内,岩性、区域构造样式和应变场的彼此独立,表明可以固定出三个地体(Foothills,Merced River和Northern Sierra)和两个特征的构造域(东、西Foothills地体)。这些地体周围为大的韧性剪切带所环绕,在平均应变强度和方向方面有差异,这种差异不是在应变类型方面。在Foothills地体中,应变强度从Foothills西部带的中强减小到Foothills东部带的较低值。在研究区内,应变强度在Melones和B(?)ar Mountai(?)s断裂带和Melons断裂带之东地体中最高。在各个地体中与区域变形有关的各种构造形迹并不能超越地体边界很大距离,因此,区域构造的多期迭加在西变质带研究区内是较为罕见的。在断裂带之外,我们在Foothills地体观测到一组更大一些的劈理面;在Northern Sierra地体则发现两组更早的劈理构造。但是,较晚的变形可使相邻地体内较早的构造活化和旋转。Foothlls地体内变形的运动学机制和时间表明断裂活动和刚性旋转发生于区域性缩短之前持续的断裂活动和断裂旋转成陡倾角。如果韧性构造带的方向代表板块运动,那么Merced River地体中的构造则表明该地体具有侏罗—第三纪时期的NNE向的正向消亡,而Foothills地体中的构造表明,约在150Ma之前。

关键词： Sierra Nevada 变质带区域构造劈理岩石类型火山砾杂砂岩韧性剪切带应变椭球体侏罗

肥胖患病率及其对患者机械通气时间和在重症监护室住院时间的影响：单中心观察研究

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中国护理管理 2017年第5期17卷 720-720页

作者： Diane M. Dennis Chrianna Bharat Timothy paterson 澳大利亚 Sir Charles Gairdner医院重症监护室澳大利亚西澳大利亚大学应用统计中心澳大利亚Sir Charles Gairdner医院研究部

目的:在重症监护室(ICU)患者样本中,为异常身体质量指数(BMI)的发生率提供概况;确定是否有任一医学专科与异常的BMI有关;分析BMI与ICU相关转归的关联。方法:选择2012年11月至2014年6月,在Sir Charles Gairdner医院的三级ICU(23张床位)... 详细信息

目的:在重症监护室(ICU)患者样本中,为异常身体质量指数(BMI)的发生率提供概况;确定是否有任一医学专科与异常的BMI有关;分析BMI与ICU相关转归的关联。方法:选择2012年11月至2014年6月,在Sir Charles Gairdner医院的三级ICU(23张床位)住院的735例成年患者(年龄中位数为58岁),进行回顾性观察。首要结果测量指标是患者的BMI,低体质量(<18.5 kg/m^2)、正常体质量(18.5~24.99 kg/m^2)、超重(25~29.99 kg/m^2)、肥胖(30~39.99 kg/m^2)或重度肥胖(≥40 kg/m^2);其他测量指标包括性别、急性生理学与慢性健康状况评分系统Ⅱ评分、住院科室、机械通气(MV)时间、住院时间(LOS)和病死率。结果:与普通人群比较,研究队列中肥胖患者的比例更高,绝大部分患者超重(33.9%)或肥胖(36.5%),BMI的中位数为27.9(IQR为7.9)。不同专科患者的BMI无统计学差异(P=0.103)。未发现异常BMI对患者病死率有负面影响(ICU,P=0.373;医院,P=0.330);正常BMI患者比其他类型BMI患者的MV时间更短,BMI对患者ICU LOS的影响取决于MV时间。与正常体质量的患者比较,机械通气时间为5天或更长的超重患者,LOS更短;重度肥胖无机械通气的患者,LOS更长。结论:尽管肥胖-疾病关系日益复杂化,而现有数据只反映了单中心ICU住院患者的不同类别的BMI;但在研究队列中,考虑护理的成本影响仍然可能是重要的,尤其是对MV和LOS的影响。

关键词：身体质量指数重症监护住院时间肥胖

A CASE OF ADDISON'S DISEASE IN A CHINESE

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中华医学杂志(英文版) 1932年第10期46卷 974-975+1079页

作者： J.L.H.paterson Lester Chinese Hospital Shanghai

The following description of a case of Addison’s disease is pub-lished because of the comparative infrequency of the *** we have not been able to find records of this disease in *** doubt amongst readers of the JOURNAL there may be some whohave met with it.I.P.1904:***.25 years of ***.A packer by *** May 24th *** June 3rd ***.—Two years ago he had diarrhoea and abdominal pain over a consider-able period,with attacks of chill and *** this time he had noticed someloss of *** had attacked him from time to *** monthsago oedema of legs and scrotum,with muscular pains,lasted for almost a month.

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Mediastinal node staging by positron emission tomographycomputed tomography and selective endoscopic ultrasound with fine needle aspiration for patients with upper gastrointestinal cancer:Results from a regional centre

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World Journal of Gastrointestinal Endoscopy 2018年第1期10卷 37-44页

作者： Chris Harrington Lyn Smith Jennifer Bisland Elisabet López González Neil Jamieson Stuart paterson Adrian John Stanley Glasgow Royal Infirmary Glasgow G4 0ETUnited Kingdom Forth Valley Royal Hospital Larbert FK5 4WRUnited Kingdom Raigmore Hospital Inverness IV2 3UJUnited Kingdom Hospital Vega Baja Orihuela 03314Spain

AIM To investigate the impact of endoscopic ultrasound-guided fine-needle aspiration(EUS-FNA) and positron emission tomography-computed tomography(PET-CT) in the nodal staging of upper gastrointestinal(GI) cancer in a tertiary referral *** We performed a retrospective review of prospectively recorded data held on all patients with a diagnosis of upper GI cancer made between January 2009 and December 2015. Only those patients who had both a PET-CT and EUS with FNA sampling of a mediastinal node distant from the primary tumour were included. Using a positive EUS-FNA result as the gold standard for lymph node involvement, the sensitivity, specificity, positive and negative predictive values(PPV and NPV) and accuracy of PET-CT in the staging of mediastinal lymph nodes were calculated. The impact on therapeutic strategy of adding EUS-FNA to PET-CT was *** One hundred and twenty one patients were included. Sixty nine patients had a diagnosis of oesophageal adenocarcinoma(Thirty one of whom were junctional), forty eight had oesophageal squamous cell carcinoma and four had gastric adenocarcinoma. The FNA results were inadequate in eleven cases and the PET-CT findings were indeterminate in two cases, therefore thirteen patients(10.7%) were excluded from further analysis. There was concordance between PET-CT and EUS-FNA findings in seventy one of the remaining one hundred and eight patients(65.7%). The sensitivity, specificity, PPV and NPV values of PET-CT were 92.5%, 50%, 52.1% and 91.9% respectively. There was discordance between PET-CT and EUS-FNA findings in thirty seven out of one hundred and eight patients(34.3%). MDT discussion led to a radical treatment pathway in twenty seven of these cases, after the final tumour stage was altered as a direct consequence of the EUS-FNA findings. Of these patients, fourteen(51.9%) experienced clinical remission of a median of nine months(range three to forty two months). CONCLUSION EUS-FNA leads to altered sta

关键词： Endoscopic ultrasound Oesophago-gastric cancer staging Oesophageal cancer Positron emission tomography-computed tomography Mediastinal nodes