检索结果-南通市图书馆

Genomic and transcriptomic analysis unveils population evolution and development of pesticide resistance in fall armyworm Spodoptera frugiperda

在线全文

学校读者我要写书评

暂无评论

Protein & Cell 2022年第7期13卷 513-531页

作者： Furong Gui Tianming Lan Yue Zhao Wei Guo Yang Dong Dongming Fang Huan Liu Haimeng Li Hongli Wang Ruoshi Hao Xiaofang Cheng Yahong Li Pengcheng Yang Sunil Kumar Sahu Yaping Chen Le Cheng Shuqi He Ping Liu Guangyi Fan Haorong Lu Guohai Hu Wei Dong Bin Chen Yuan Jiang Yongwei Zhang Hanhong Xu Fei Lin Bernard Slippers alisa Postma Matthew Jackson Birhan Addisie Abate Kassahun Tesfaye Aschalew Lemma Demie Meseret Destaw Bayeleygne Dawit Tesfaye Degefu Feng Chen Paul K.Kuria Zachary M.Kinyua Tong-Xian Liu Huanming Yang Fangneng Huang Xin Liu Jun Sheng Le Kang State Key Laboratory for Conservation and Utilization of Bioresources in Yunnan Yunnan Agricultural UniversityKunming 650201China State Key Laboratory of Agricultural Genomics BGI-ShenzhenShenzhen 518083China State Key Laboratory of Integrated Management of Pest Insects and Rodents Institute of ZoologyChinese Academy of SciencesBeijing 100101China Beijing Institutes of Life Science Chinese Academy of SciencesBeijing 100101China MGI BGI-ShenzhenShenzhen 518083China BGI-Qingdao BGI-ShenzhenQingdao 266555China BGI-Yunnan No.389 Haiyuan RoadHigh-tech Development ZoneKunming 650106China China National GeneBank Jinsha RoadDapeng New DistrictShenzhen 518120China Department of Biology University of Copenhagen2100 CopenhagenDenmark Guangdong Provincial Key Laboratory of Genome Read and Write BGI-ShenzhenShenzhen 518120China Guangdong Provincial Academician Workstation of BGI Synthetic Genomics BGI-ShenzhenShenzhen 518120China Yunnan Plateau Characteristic Agriculture Industry Research Institute Kunming 650201China College of Plant Health and Medicine Qingdao Agricultural UniversityQingdao 266109China Department of Entomology Louisiana State University Agricultural CenterBaton RougeLA 70803USA CAS Center for Excellence in Biotic Interactions University of Chinese Academy of SciencesBeijing 100101China Yunnan Plant Protection and Quarantine Station Kunming 650034China State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources South China Agricultural UniversityGuangzhou 510642China BGI-Americas One Broadway14th FloorCambridgeMA 02142USA Departme nt of Biochemistry Gen etics and MicrobiologyForestry and Agricultural Biotech no logy InstituteUn iversity of PretoriaPretoriaSouth Africa Ethiopian Biotechnology Institute Addis AbabaEthiopia College of Natural Science Addis Ababa UniversityAddis AbabaEthiopia Melkassa Agricultural Research Center Ethiopian Institute of Agricultural ResearchMelkassaAddis AbabaEthiopia Kenya Agricultural and Livestock Res

The fall armyworm(FAW),Spodoptera frugiperda,is a destructive pest native to America and has recently become an invasive insect pest in *** of its rapid spread and great risks in China,understanding of FAW genetic background and pesticide resistance is urgent and essential to develop effective management ***,we assembled a chromosome-level genome of a male FAW(SFynMstLFR)and compared re-sequencing results of the populations from America,Africa,and *** identification of 163 individuals collected from America,Africa and China showed that both C and R strains were found in the American pop-ulations,while only C strain was found in the Chinese and African ***,population geno-mics analysis showed that populations from Africa and China have close relationship with significantly genetic differentiation from American *** toge-ther,FAWs invaded into China were most likely origi-nated from *** genomics analysis displayed that the cytochrome p450 gene family is extremely expanded to 425 members in FAW,of which 283 genes are specific to *** of Chinese populations with twenty-three pesticides showed the variant patterns of transcriptome profiles,and several detoxification genes such as AOX,UGT and GST spe-cially responded to the *** findings will be useful in developing effective strategies for manage-ment of FAW in China and other invaded areas.

关键词： Spodoptera frugiperda chromosome-level genome population differentiation cytochrome p450 pesticides

Impaired swallowing mechanics of post radiation therapy head and neck cancer patients: A retrospective videofluoroscopic study

在线全文

学校读者我要写书评

暂无评论

World Journal of Radiology 2016年第2期8卷 192-199页

作者： William G Pearson Jr alisa A Davidoff Zachary M Smith Dorothy E Adams Susan E Langmore Department of Cellular Biology and Ana-tomy Medical College of Georgia at Georgia Regents University Department of Otolaryngology Medical College of Georgia at Georgia Regents University Sargent College Boston University Department of Otolaryngology Head and Neck Surgery Boston University School of Medicine

AIM: To determine swallowing outcomes and hyolaryngeal mechanics associated with post radiation therapy head and neck cancer(rt HNC) patients using videofluoroscopic swallow studies. METHODS: In this retrospective cohort study, video-fluoroscopic images of rt HNC patients(n = 21) were compared with age and gender matched controls(n = 21). Penetration-aspiration of the bolus and bolus residue were measured as swallowing outcome variables. Timing and displacement measurements of the anterior and posterior muscular slings elevating the hyolaryngeal complex were acquired. Coordinate data of anatomical landmarks mapping the action of the anterior muscles(suprahyoid muscles) and posterior muscles(long pharyngeal muscles) were used to calculate the distance measurements, and slice numbers were used to calculate time intervals. Canonical variate analysis with post-hoc discriminant function analysis was performed on coordinate data to determine multivariate mechanics of swallowing associated with treatment. Pharyngeal constriction ratio(PCR) was also measured to determine if weak pharyngeal constriction is associated with post radiation ***: The rt HNC group was characterized by poor swallowing outcomes compared to the control group in regards to: Penetration-aspiration scale(P < 0.0001), normalized residue ratio scale(NRRS) for the valleculae(P = 0.002) and NRRS for the piriform sinuses(P = 0.003). Timing and distance measurements of the anterior muscular sling were not significantly different in the two groups, whereas for the PMS time of displacement was abbreviated(P = 0.002) and distance of excursion was reduced(P = 0.02) in the rt HNC group. A canonical variate analysis shows a significant reduction in pharyngeal mechanics in the rt HNC group(P < 0.0001). The PCR was significantly higher in the test group than the control group(P = 0.0001) indicating reduced efficiency in pharyngeal clearance. CONCLUSION: Using videofluoroscopy, this study shows rt HNC pati

关键词： Swallow mechanics Post radiation Head and neck cancer Fluoroscopy Anatomy

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

激动人心的丙肝治疗革命

中国处方药 2010年第7期9卷 16-16页

作者： alisa Opar 朱宝益

最新公布的III期临床数据显示,telaprevir——首个治疗丙肝的蛋白酶抑制剂,显著提高了丙肝的治愈率,给丙肝药物研发带来了美好的前景。

关键词：丙肝治疗激动蛋白酶抑制剂数据显示 Ⅲ期临床药物研发治愈率

Antioxidant Activity and Phenolic Content of Okoubaka aubrevillei (Anunuebe) Fruit Pychnobotrya nitida (Osu) Leaf Extracts

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Science and Engineering(B) 2022年第5期11卷 206-212页

作者： Christopher O.alisa Edith NOkoye Peter C.Okeke Sylvia O.Anyadogh-Nwadike Lovell A.gwaramgbo Jailen Doyle Department of Chemistry Federal University of TechnologyP.M.B 1526 OwerriNigeria Department of Biotechnology Federal University of TechnologyP.M.B 1526 OwerriNigeria Opec Research Consult AwkaAnambraNigeria Department of Chemistry Dillard UniversityNew OrleansLouisianaUSA

The antioxidant activity and the total phenolic content of Okoubaka aubrevillei(Anunuebe)and Pychnobotrya nitida(Osu)plant extracts were investigated in this study to justify their ethno medicinal *** antioxidant activity of crude extracts of both plants was investigated using the scavenging effect on DPPH(2,2-Diphenyl-1-Picrylhydrazyl Radical)assay,while the total phenolic content was determined by the Folin-Ciocalteu reagent *** compared to standard drug vitamin C at various concentrations,both extracts exhibited potent antioxidant activity that increased with increasing concentration of *** high positive linear correlation between the antioxidant capacity and the total phenolic content suggests that the antioxidant capacity of both plants can be largely attributed to their phenolic *** on these findings,*** fruit and *** leaf could be potential natural antioxidant sources for preventing free radical-induced diseases.

关键词： Medicinal plants Okoubaka aubrevillei Pychnobotrya nitida phenolic content antioxidant capacity

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

本期主题:快乐英语,快乐生活

阅读 2019年第92期 2-2页

作者：王怡雯江苏省盐城市亭湖区实验小学四(4)班

Hello, everyone!我叫王怡雯,My English name is alisa. I like reading and dancing. I love English very ***! This is our English lesson in the playground.大家用身体合作摆出一个个英文字母。你想加入我们吗?Have a try!学习... 详细信息

关键词：快乐英语

Evaluating chromosomal segregation in a family where both spouses carry an autosomal translocation

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Reproductive and Developmental Medicine 2023年第3期7卷 189-192页

作者： Irina L.Puppo Ziravard N.Tonyan Alsu F.Saifitdinova Julia A.Loginova Anna A.Kinunen alisa N.Panina Julia R.Pastuhova Olga A.Leonteva Olga G.Chiryaeva Olga V.Malysheva Oleg S.Glotov Irina V.Poliakova Andrey V.Tikhonove Tatyana V.Vavilova Irina L.Menshikova Elvira V.Isakova Andrey S.Glotov Natalya K.Bichevaya International Centre for Reproductive Medicine Saint-Petersburg 197350Russia Department of Laboratory Medicine and Genetics Almazov National Medical Research CentreSaint-Petersburg197341Russia Department of Genomic Medicine D.O.Ott's Institute of ObstetricsGynecologyand ReproductologySaint-Petersburg 199034Russia Department of Biology.Herzen State Pedagogical University of Russia Saint-Petersburg 191186Russia DiaCarta Inc.2600 Hilltop DriveRichmondCA 94806 St.Petersburg Centre for Medical Genetics Saint Petersburg194044Russia Department of ExperimentalMedical Virology MolecularGenetics and Biobankingof Pediatric Researchand Clinical Center for Infectious DiseasesSaint-Petersburg 197022Russia Medical institute of Surgut State University Surgut 628403 Russia CerbaLab Ltd. Saint-Petersburg 199106Russia

Autosomal reciprocal translocations represent exchanges of chromatin fragments between non-homologous *** are facilitated by the creation of quadrivalent structures during the first meiotic division,which are characterized by the length of the translocated and centric segments,asymmetry,and the presence of terminal breakpoints,all of which may impact segregation ***,we report a rare case of multiple reciprocal translocations within a single *** includes the evaluation of the translocations in each of the spouses and an analysis of their chromosome segregation patterns as determined by the constellation of universal characteristics in each of their *** obtained results will be of interest to fundamental biology,as they will expand the understanding of the factors affecting chromosome segregation during meiosis.

关键词： Embryo viability Genetic counseling Pre-implantation genetic testing Quadrivalent characteristics