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2018第三届“天工精制”国际珠宝设计作品大赛获奖作品欣赏

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中国宝石 2018年第6期27卷 82-87页

作者： alisa(编辑) 唐贺(版式设计) 不详

“初心在方寸,咫尺匠心难”,由国家珠宝玉石质量监督检验中心、中国珠宝玉石首饰行业协会主办,《中国宝石》杂志社有限责任公司携手深圳市金银珠宝创意产业协会承办的2018第三届“天工精制”国际珠宝作品设计大赛,在众多企业、设计师、... 详细信息

“初心在方寸,咫尺匠心难”,由国家珠宝玉石质量监督检验中心、中国珠宝玉石首饰行业协会主办,《中国宝石》杂志社有限责任公司携手深圳市金银珠宝创意产业协会承办的2018第三届“天工精制”国际珠宝作品设计大赛,在众多企业、设计师、大专院校的热情参与下完美落幕。大赛从筹备至今,历时半年多,收到众多参赛作品。经过评审们认真地甄选和评判,其中有43件作品及一所院校分别获得各组别金、银、铜奖、最佳单项奖和特别奖,并有一家企业荣获年度最佳企业奖。

关键词：珠宝玉石作品欣赏设计作品精制质量监督检验中心行业协会创意产业大专院校

The Use of Hypothermically Stored Amniotic Membrane for Cartilage Repair: A Sheep Study

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Stem Cell Discovery 2015年第4期5卷 62-71页

作者： Samuel K. Tabet alisa L. Clark Eric B. Chapman Doug Thal New Mexico Orthopaedic Associates Albuquerque NM USA School of Medicine University of New Mexico Albuquerque NM USA Thal Equine LLC Albuquerque NM USA

Objective: To evaluate the use of hypothermically stored human amniotic membrane for cartilage repair in adult sheep. Studies show that human amniotic membrane contains pluripotent mesenchymal stem cells that can be influenced to produce chondrocytes. It is unknown if human amniotic cells can produce hyaline-like cartilage. This study evaluates the use of hypothermically stored amniotic membrane (HSAM) to fill chondral defects in a sheep model. We hypothesized HSAM would fill defects with hyaline-like cartilage with chondrocytes populating the matrix. One sheep was used as a control, and four sheep received amniotic membrane. Two of these sheep were used as a normal control comparison. A 1 cm2 defect was created on the trochlear grove in all specimens. Each membrane was sized and laid over with the stromal layer facing the subchondral bone and covered with Fibrin sealant. The knees were harvested at five months and underwent morphological, histological, and immunohistological evaluation based on the original validated scoring system by O’Driscoll. The control defect didn’t fill in with hyaline cartilage or fibrocartilage. The defects that successfully retained the graft had evidence of diffuse chondrocyte cell proliferation and showed a stromal matrix similar to hyaline cartilage. The graft samples showed a near 100% morphological fill in the HSAM defect contrasting to <10% fill in the control defect. The retained HSAM grafts scored 2.5 on a 0 - 3 cartilage appearance scale compared with 0.5 for the control defects. HSAM is a potential source of pluripotent cells that can influence chondrogenesis in a sheep model. The implications for application in a human model are promising and warrant further study.

关键词： Mesenchymal Stem Cells Chondrocytes Cartilage Repair Amniotic Membrane

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生物标记物在ASCO大放异彩

中国处方药 2008年第7期7卷 85-86页

作者： alisa Opar 梁伟

随着越来越多的生物标记物走向成熟,将来就可以挑选出哪些患者会对治疗有反应,哪些患者对治疗没反应,而不必让患者的时间浪费在无效的治疗上。

关键词：生物标记物 ASCO 治疗反应

Stimulation of decidua development by transplantation of endometrial stem cells

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Journal of Biomedical Science and Engineering 2013年第8期6卷 59-65页

作者： alisa P. Domnina Victoria I. Zemelko Vyacheslav M. Mikhailov Nikolay N. Nikolsky Institute of Cytology Russian Academy of Sciences St.-Petersburg Russia

On all terms of pregnancy, insolvency of decidual reaction of endometrial cells is one of the reasons of miscarriages and fetal growth delay. The insufficient decidualization of endometrum leads to infertility in such pathologies, as Asherman’s syndrome and an endometrium atrophy. However, there are data on successful application of autologous bone marrow MSCs for Asherman’s syndrome treatment. The aim of this work was to assay the effect of endometrial mesenchymal stem cell (eMSC) transplantation for decidualization process in pseudopregnant rat. Our study showed that injection of human eMSC suspension into the uterine lumen of pseudopregnant rats facilitated more intensive development of decidua in comparison with phosphate buffed saline (PBS) injection in the control uterine horn. Histological analysis of decidua sections did not reveal any alterations in cell differentiation or tissue structure. In conclusion, we demonstrated for the first time that eMSC transplantation assists the development of all decidual tissue elements. It opens the possibility that eMSCs may be applied for cell therapy of infertility associated with decidualzation insufficiency.

关键词： Decidualization Pseudopregnancy Human Mesenchymal Stem Cells of Endometrium Menstrual Blood

Lam Research的先进深硅刻蚀技术

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电子工业专用设备 2015年第3期44卷 54-54,57页

作者： Jay Minami alisa Hart 泛林研究公司

在一个人们期望即时信息的社会,等上几秒钟,时间似乎变得很长。随着万亿传感器的视野和物联网（I OT）互联网的不断发展,对于＂智能传感器＂出现了明显的需求：即对大量数据进行分类,区分有用信息和噪音,节省珍贵的几秒钟。随着智能传... 详细信息

在一个人们期望即时信息的社会,等上几秒钟,时间似乎变得很长。随着万亿传感器的视野和物联网（I OT）互联网的不断发展,对于＂智能传感器＂出现了明显的需求：即对大量数据进行分类,区分有用信息和噪音,节省珍贵的几秒钟。随着智能传感器的发展,微机电系统（MEMS）、电源装置以及先进封装蚀刻应用需要更精确的控制和更高的生产率。

关键词：智能传感器刻蚀技术 Lam Research 先进封装微机电系统电源装置物联网即时信息均匀性腔壁

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2018年亚洲苏富比十大成交拍品亮相

中国宝石 2018年第6期27卷 132-134页

作者： alisa(编辑) 唐贺(版式设计) 不详

2018年是苏富比扎根亚洲四五十年来以来成绩最好的一年,年度拍卖总额高达9.85亿美元(76.8亿港元),亦是苏富比连续第三年引领亚洲拍卖市场。

关键词：亚洲拍卖市场

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摩根石祖母绿家族的温柔少女

中国宝石 2018年第6期27卷 158-159页

作者：孙雯 alisa(编辑) 唐贺(版式设计) 不详

柔美甜蜜的摩根石(Morganile)是绿柱石家族的成员,不同于祖母绿、海蓝宝等绿柱石家族成员,摩根白的柔美光芒与色泽使人格外心醉。

关键词：祖母绿根石少女绿柱石

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英国高端时尚品牌吸引中国新贵

英语沙龙（初级版） 2010年第9期 12-13页

作者： alisa Gould-Simon 赵雨萌

几十年以来，西方时尚品牌一直将中国视为廉价原材料和劳动力市场，但最近几个月，这个国家因另外一个原因吸引了时尚界的眼球：由于其高速发展的经济，许多高端时尚品牌都宣布他们有意在中国大陆扩大经营。

关键词：时尚品牌中国大陆英国劳动力市场原材料经济

A dahlia flower extract has antidiabetic properties by improving insulin function in the brain

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Life Metabolism 2023年第4期2卷 39-50页

作者： Dominik Pretz Philip M.Heyward Jeremy Krebs Joel Gruchot Charles Barter Pat Silcock Nerida Downes Mohammed Zubair Rizwan alisa Boucsein Julia Bender Elaine J.Burgess Geke Aline Boer Pramuk Keerthisinghe Nigel B.Perry Alexander Tups Centre for Neuroendocrinology School of Biomedical SciencesUniversity of OtagoDunedin 9054New Zealand Department of Physiology School of Biomedical SciencesUniversity of OtagoDunedin 9054New Zealand Maurice Wilkins Centre for Molecular Biodiscovery University of AucklandAuckland 1010New Zealand Department of Medicine University of OtagoWellingtonWellington South 6242New Zealand Centre for Endocrine Diabetes and Obesity Research Wellington Regional HospitalNewtownWellington 6021New Zealand Product Development Research Centre University of OtagoDunedin 9054New Zealand Department of Chemistry The New Zealand Institute for Plant and Food ResearchUniversity of OtagoDunedin 9054New Zealand

Butein,a rare chalcone found in the toxic plant Toxicodendron vernicifluum,has been shown to regulate glucose homeostasis via inhibition of the nuclear factor kappa-B kinase subunit beta(IKKβ)/nuclear factor kappa B(NF-κB)pathway in the ***,we investigated whether the nonpoisonous plant Dahlia pinnata could be a source of butein as a potential treatment for type 2 diabetes(T2D).In mice fed a high-fat diet(HFD)to induce glucose intolerance,an oral *** petal extract improved glucose tolerance at doses of 3.3 mg/kg body weight and 10 mg/kg body ***,this effect was not mediated by butein alone but by butein combined with the closely related flavonoids,sulfuretin and/or ***,the extract improved systemic insulin *** of phosphatidylinositol 3-kinase to block insulin signaling in the brain abrogated the glucoregulatory effect of the orally administered *** extract reinstated central insulin signaling and normalized astrogliosis in the hypothalamus of HFD-fed *** NF-κB reporter zebrafish to determine IKKβ/NF-κB activity,a potent anti-inflammatory action of the extract was found.A randomized controlled crossover clinical trial on participants with predia-betes or T2D confirmed the safety and efficacy of the extract in *** conclusion,we identified an extract from the flower petals of *** as a novel treatment option for T2D,potentially targeting the central regulation of glucose homeostasis as a root cause of the disease.

关键词： inflammation hypothalamus signal transduction neuroendocrine arcuate nucleus