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Supply chain process optimisation via the management of variance

Journal of Management Analytics 2018年第2期5卷 136-153页

作者： Farhad Nabhani Christian Uhl Florian Kauf alireza shokri Department of Science and Mechanical Engineering Teesside UniversityMiddlesbroughUK Department of Product Development and Mechatronics University of Ravensburg-WeingartenRavensburgGermany Department of Operations Logistics and Supply Chain ManagementUniversity of NorthumberiaNewcastleUK

This paper presents a new optimisation approach for variance within a supply chain management *** approach is presented by the variance cube of purchasing(VCP)that involves a lean method for variance optimisation,namely the cost and variance driver *** approach focuses on the optimisation and the control of existing process variance within the supply *** application of the cube is presented by a case study involving a globally acting Tier 1 supplier,who produces steering systems for passenger cars and commercial *** this case,the sourcing process of this Tier 1 supplier will be analysed,evaluated and optimised regarding *** variance is presented in the form of the number of suppliers who are involved in the sourcing *** existing process variance,like an unnecessary huge number of suppliers within the sourcing process,is a type of ***,money,quality and technology can be saved through a greater understanding of the optimal number of suppliers within a sourcing *** results of the case study led to a generalised method to optimise the existing process variance,present cost improvements as well as optimising the key performance indicator to manage the number of suppliers in the sourcing *** general approach can be used for other company departments like logistics and for different industries other than *** insights of this article support the operative user and the strategic company management in order to reduce and improve unnecessary variance in different *** structured analysis of supply chain process variance via the VCP and the key performance indicator“optimal supplier number per sourcing process”are new to company management.

关键词： sourcing process digital purchasing process standardisation variance and complexity management

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First survey of hard ticks(Acari: Ixodidae) on cattle, sheep and goats in Boeen Zahra and Takistan counties, Iran

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Asian Pacific Journal of Tropical Biomedicine 2012年第6期2卷 489-492页

作者： Masoomeh Shemshad Khadijeh Shemshad Mohammad Mehdi Sedaghat Majid shokri alireza Barmaki Mojgan Baniardalani Javad Rafinejad Department of Agricultural Extension and Education Science and Research Branch Islamic Azad University Department of Entomology Science and Research Branch Islamic Azad University Department of Medical Entomology and Vector Control School of Public Health Tehran University of Medical Sciences Parasitic and Protozoan Diseases Control Office Qazvin Veterinary Organization Department of Medical Entomology and Vector Control Health Center of Takistan County Evaluation Management and Development Center Deputy of Research Ministry of Health and Medical Education

Objective:To carry out the distribution survey of hard ticks of livestock in Boeen Zahra and Takistan counties of Qazvin province from April 2010 to September ***:Nearly about 2638 sheep, 461 goats and 318 cattle of 38 herds in different geographical areas were searched for tick ***:The species compositions collected from the livestock of Boeen Zahra and Takistan wereHaemaphysalis concinna(0.63%),Haemaphysalis sulcata(12.66%),Hyalomma anatolicum(3.80%),Hyalomma asiaticum(3.16%),Hyalomma detritum(5.70%),Hyalomma dromedarii(28.48%),Hyalomma marginatum(13.29%),Hyalomma schulzei(1.89%),Rhipicephalus bursa(3.16%) and Rhipicephalus sanguineus(3.16%), and for Takistan's livestock were Hyalomma dromedarii(9.86%),Hyalomma marginatum(13.29%),Hyalomma schulzei(1.89%) and Rhipicephalus sanguineus(3.16%), respectively. Hard ticks compositions in different topographic areas were *** had the most prevalence in the ***:The veterinary and public health investigation of the above species should be taken.

关键词： Hard ticks Ixodidae Cattle Sheep Goats Boeen Zahra Takistan Iran

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Association of monoctye expression of Toll-like receptor 4 and its related cytokines with coronary luminal stenosis

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Advances in Bioscience and Biotechnology 2013年第7期4卷 19-25页

作者： Bahador Bagheri Bahram Sohrabi Aliakbar Movassaghpur Simin Mashayekhi Afagh Garjani Mehriar shokri Mohammad Noori alireza Garjani Department of Pharmacology Faculty of Pharmacy Tabriz University of Medical Sciences Tabriz Iran Departmentof Clinical Pharmacy Faculty of Pharmacy Tabriz University of Medical Sciences Tabriz Iran Hematology Research Centre Tabriz University of Medical Sciences Tabriz Iran School of Medicine Tabriz University of Medical Sciences Tabriz Iran Shahid Madani Heart Hospital Tabriz University of Medical Sciences Tabriz Iran

Toll-like receptors are well-defined barriers in innate immunity. Among them hTLR4 on the surface of monocytes, plays a critical role in the formation of atherosclerotic plaques, plaque instability and arterial remodeling through production of inflammatory cytokines. This study was designed to examine the association of hTLR4 monocyte expression and response with the severity of coronary stenosis in patients with stable angina (SA). Blood samples were obtained from 39 patients with SA who were scheduled for a coronary angiography and from 28 healthy volunteers. The samples were collected before the procedure. Expression of hTLR4 on CD14+ monocytes and serum levels of TNF-α and IL-1β were measured using flowcytometry and ELISA techniques respectively. Percentage stenosis diameter was measured by comparing the area of coronary stenosis to an adjacent normal segment of the vessel. Compared with control group, patients showed upregulation of hTLR4+/CD14+ monocytes. Furthermore, patients with more severe coronary stenosis exhibited enhanced expression of hTLR4+/CD14+ monocytes (p α (p β. In addition, significant correlations were seen between percentage stenosis diameter and monocyte expression of hTLR4 as well as TNF-α. hTLR4 monocytic expression and related cytokines are positively associated percentage stenosis diameter. These results suggest that hTLR4 activity may be involved in progression of atherosclerosis.

关键词： Atherosclerosis Cytokines Inflammation hTLR4

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