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The role of rhizobacteria in rice plants: Growth and mitigation of toxicity

Journal of Integrative Agriculture 2018年第12期17卷 2636-2647页

作者： Marcela C F Rêgo aline F Cardoso Thayná da C Ferreira Marta C C de Filippi Telma F V Batista Rafael G Viana Gisele B da Silva Plant Protection Laboratory Institute of Agrarian Sciences Federal Rural University of Amazon Phytopathology Laboratory Brazilian Enterprise for Agricultural Research-Rice and Beans

Allelopathic compounds reduce the growth and productivity of upland rice plants, especially in consecutive plantations. The rhizobacteria Pseudomonas fluorescens BRM-32111 and Burkholderia pyrrocinia BRM-32113 have been recorded as growth promoters in rice. This study was developed to understand the effect of the application of rhizobacteria on upland rice plants in consecutive plantations. Experiments were conducted in a completely randomized design with four replications of four treatments: rice seed inoculated with P. fluorescens BRM-32111, rice seed inoculated with B. pyrrocinia BRM-32113(both sown on soil with rice residue), non-inoculated plants sown on soil with rice residue(control with residue(WR)), and non-inoculated plants on soil with no residue(NR). Roots and seedling growth were adversely affected by allelopathic compounds in control WR plants. Plants inoculated with rhizobacteria P. fluorescens BRM-32111 or B. pyrrocinia BRM-32113 induced an increase of 88% in biomass, 3% in the leaf area, 40% in length, 67% in root biomass, 21% in chlorophyll a, 53% in chlorophyll(a+b), 50% in rate of carbon assimilation(A), 227% in A/rubisco carboxylation efficiency(Ci) and 63% in water use efficiency(WUE) compared to control WR plants. These results indicate that rhizobacteria P. fluorescens BRM-32111 and B. pyrrocinia BRM-32113 increase the tolerance of rice plants to stress from allelochemicals. There are possible practical agricultural applications of these results for mitigating the effects of environmental allelochemistry on upland rice.

关键词： allelopathy B.pyrrocinia P.fluorescens rhizobacteria rice

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Surgical treatment of fibrolamellar hepatocellular carcinoma:an underestimated malignant tumor?

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Hepatobiliary & Pancreatic Diseases International 2014年第6期13卷 618-621页

作者： Paulo Herman aline Lopes Chagas Marcos Vinicius Perini Fabricio Ferreira Coelho Gilton Marques Fonseca Venancio Avancini Ferreira Alves Flair José Carrilho Ivan Cecconello Digestive Surgery Division Department of GastroenterologyUniversity of Sao Paulo School of MedicineAvenida Doutor Enéas de Carvalho Aguiar255Instituto Central9°andarSala 9074CEP:05403-900Cerqueira Cesar-Sao PauloSPBrazil Digestive Surgery Division Department of GastroenterologyUniversity of Sao Paulo School of MedicineAvenida Doutor Enéas de Carvalho Aguiar255Instituto Central9°andarSala 9074CEP:05403-900Cerqueira Cesar-Sao PauloSPBrazil Department of Pathology University of Sao Paulo School of MedicineAvenida Doutor Enéas de Carvalho Aguiar255Instituto Central9°andarSala 9074CEP:05403-900Cerqueira Cesar-Sao PauloSPBrazil Digestive Surgery Division Department of GastroenterologyUniversity of Sao Paulo School of MedicineAvenida Doutor Enéas de Carvalho Aguiar255Instituto Central9°andarSala 9074CEP:05403-900Cerqueira Cesar-Sao PauloSPBrazil

BACKGROUND： Fibrolamellar hepatocellular carcinoma （FLHCC） is a rare disease with an indolent behavior. Its prognosis is better than that of patients with hepatocellular carcinoma. The authors present their experience with resection of FLHCC. METHODS： Twenty-one patients with FLHCC were treated at our institution between 1990 and 2012. Of these patients, 14 were subjected to resection of the tumor. Patient demographics, medical history, results of imaging studies and laboratory tests, surgical data, and pathologic findings were evaluated. RESULTS： The median age of the patients at the diagnosis of the tumor was 20 years and 14 patients were female. None of the patients had tumor-associated chronic liver disease or cirrhosis. The mean tumor size was 12.8 cm （range 6-19） and 18 patients had a single liver nodule. Fourteen patients were subjected to hepatectomy and six of them had lymph node metastases resected. Pathologic evaluation revealed that 5 （35.7%） patients had major vascular invasion. Tumor recurrence was seen in 8 patients （66.7%）, during a follow-up. The median survival time for patients who were subjected to resection was 36 months. The 5-year overall survival rate and disease free survival rate were 28.0% and 8.5%, respectively. Univariate analysis showed that vascular invasion was the only variable associated with the disease free survival ***： Despite an aggressive treatment, patients with FLHCC presented unexpected low survival rates. It seems that an underestimated malignant behavior is attributed to this disease, and that the forms of adjuvant treatment should be urgently evaluated.

关键词： fibrolamellar hepatocellular carcinoma hepatectomy hepatocellular carcinoma lymph node excision survival

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Relativistic-intensity near-single-cycle light waveforms at kHz repetition rate

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Light(Science & Applications) 2020年第1期9卷 1572-1580页

作者： Marie Ouille aline Vernier Frederik Bohle Maimouna Bocoum Aurelie Jullien Magali Lozano Jean-Philippe Rousseau Zhao Cheng Dominykas Gustas Andreas Blumenstein Peter Simon Stefan Haessler Jerome Faure Tamas Nagy Rodrigo Lopez-Martens Laboratoire d’Optique Appliquee CNRSEcole PolytechniqueENSTA ParisInstitut Polytechnique de Paris181 chemin de la Huniere et des Joncherettes91120 PalaiseauFrance Ardop Engineering Cite de la Photonique11 Avenue de la Canterannebat.Pleione33600 PessacFrance Laser-Laboratorium Gottingen e.V. Hans-Adolf-Krebs-Weg 137077 GottingenGermany Max Born Institute for Nonlinear Optics and Short Pulse Spectroscopy Max-Born-Strasse 2A12489 BerlinGermany

The development of ultra-intense and ultra-short light sources is currently a subject of intense research driven by the discovery of novel phenomena in the realm of relativistic optics,such as the production of ultrafast energetic particle and radiation beams for *** has been a long-standing challenge to unite two hitherto distinct classes of light sources:those achieving relativistic intensity and those with pulse durations approaching a single light *** the former class traditionally involves large-scale amplification chains,the latter class places high demand on the spatiotemporal control of the electromagnetic laser ***,we present a light source producing waveformcontrolled 1.5-cycle pulses with a 719 nm central wavelength that can be focused to relativistic intensity at a 1 kHz repetition rate based on nonlinear post-compression in a long hollow-core *** unique capabilities of this source allow us to observe the first experimental indications of light waveform effects in laser wakefield acceleration of relativistic energy electrons.

关键词： repetition intensity light

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Reliability of electric vehicle charging infrastructure:A cross-lingual deep learning approach

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Communications in Transportation Research 2023年第1期3卷 81-91页

作者： Yifan Liu Azell Francis Catharina Hollauer M.Cade Lawson Omar Shaikh Ashley Cotsman Khushi Bhardwaj aline Banboukian Mimi Li Anne Web Omar Isaac Asensio School of Public Policy Georgia Institute of TechnologyAtlanta30332USA Sam Nunn School of International Affairs Georgia Institute of TechnologyAtlanta30332USA School of Civil&Environmental Engineering Georgia Institute of TechnologyAtlanta30332USA H.Milton Stewart School of Industrial and Systems Engineering Georgia Institute of TechnologyAtlanta30332USA School of Computer Science Georgia Institute of TechnologyAtlanta30332USA School of Computer Science Stanford UniversityPalo Alto94305USA School of Economics Georgia Institute of TechnologyAtlanta30332USA Institute for Data Engineering&Science(IDEaS) Georgia Institute of TechnologyAtlanta30332USA

Vehicle electrification has emerged as a global strategy to address climate change and emissions externalities from the transportation *** of charging infrastructure is needed to accelerate technology adoption;however,managers and policymakers have had limited evidence on the use of public charging stations due to poor data sharing and decentralized ownership across *** this article,we use machine learning based classifiers to reveal insights about consumer charging behavior in 72 detected languages including *** investigate 10 years of consumer reviews in East and Southeast Asia from 2011 to 2021 to enable infrastructure evaluation at a larger geographic scale than previously *** find evidence that charging stations at government locations result in higher failure rates with consumers compared to charging stations at private points of *** evidence contrasts with predictions in the *** European markets,where the performance is closer to *** also find that networked stations with communication protocols provide a relatively higher quality of charging services,which favors policy support for connectivity,particularly for underserved or remote areas.

关键词： Electric vehicles Consumer behavior Charging infrastructure Public policy Machine learning Natural language processing Transformer algorithms

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Influence of fire on woody vegetation of savanna and forest formations in the Cerrado biome

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Journal of Forestry Research 2023年第5期34卷 1207-1216页

作者： aline das Gracas Costa Fillipe Tamiozzo Pereira Torres Gumercindo Souza Lima Fabiano Rodrigues de Melo Carlos Moreira Miquelino Eleto Torres Bruno Leao Said Schettini Vicente Paulo Santana Neto AndréLuiz Lopes de Faria Department of Forest Engineering Federal University of VicosaUFVVicosaMG 36570-900Brazil Department of Geography Federal University of VicosaUFVVicosaMG 36570-900Brazil

Wildfires have environmental,economic,and social impacts,and can shape the landscape and benefit ecosystems such as the *** study evaluated the diversity,similarity,and floristic and structural differences of woody savanna and forest formations of the Cerrado,when affected and not affected by ***-eight 25-400m2 plots were randomly allocated and divided into Burnt Cerrado and Unburnt Cerrado,Burnt Forest,and Unburnt Forest,and divided into three levels of inclusion according to diameter class(smaller than 2 cm,2-5 cm and larger than5 cm).Species were identified,DBH and height measured,and phyto sociological parameters such as volume,diversity,and floristic similarity *** Cerrado had lower diversity,density,and dominance at all inclusion levels compared to the Unburnt Cerrado,and showed similarities between treatments at the inclusion *** Forest had smaller differences in diversity,density,and dominance than Unburnt *** formation was similar at level 1 of inclusion and in the total ***,it was dissimilar at lower *** lower density and diversity of species at the lowest levels of inclusion was associated with mortality from fire.

关键词： Biodiversity Brazil Burning Floristic Phytosociology

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Growth and differentiation of human induced pluripotent stem cell(hiPSC)-derived kidney organoids using fully synthetic peptide hydrogels

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Bioactive Materials 2023年第3期21卷 142-156页

作者： Niall J.Treacy Shane Clerkin Jessica L.Davis Ciar´an Kennedy aline F.Miller Alberto Saiani Jacek K.Wychowaniec Dermot F.Brougham John Crean Diabetes Complications Research Centre University College Dublin(UCD)Conway Institute of Biomolecular and Biomedical Research and BelfieldDublin 4Ireland UCD School of Biomolecular and Biomedical Science BelfieldDublin 4Ireland Department of Materials&Manchester Institute of Biotechnology(MIB) School of Natural SciencesFaculty of Science and EngineeringThe University of ManchesterUK UCD School of Chemistry University College DublinBelfieldDublin 4Ireland

Human induced pluripotent stem cell(hiPSC)-derived kidney organoids have prospective applications ranging from basic disease modelling to personalised ***,there remains a necessity to refine the bio-physical and biochemical parameters that govern kidney organoid *** within fully-controllable and physiologically relevant 3D growth environments will be critical to improving organoid reproducibility and ***,we matured hiPSC-derived kidney organoids within fully synthetic self-assembling peptide hydrogels(SAPHs)of variable stiffness(storage modulus,G′).The resulting organoids con-tained complex structures comparable to those differentiated within the animal-derived matrix,***-cell RNA sequencing(scRNA-seq)was then used to compare organoids matured within SAPHs to those grown within Matrigel or at the air-liquid interface.A total of 13,179 cells were analysed,revealing 14 distinct *** compositional analysis revealed a larger proportion of nephron cell types within Transwell-derived organoids,while SAPH-derived organoids were enriched for stromal-associated cell ***,dif-ferentiation within a higher G’SAPH generated podocytes with more mature gene expression ***-tionally,maturation within a 3D microenvironment significantly reduced the derivation of off-target cell types,which are a known limitation of current kidney organoid *** work demonstrates the utility of syn-thetic peptide-based hydrogels with a defined stiffness,as a minimally complex microenvironment for the selected differentiation of kidney organoids.

关键词： Human kidney organoids Fully synthetic matrices Self-assembling peptide hydrogels Single-cell RNA sequencing

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Estrogen-mediated downregulation of HIF-1αsignaling in B lymphocytes influences postmenopausal bone loss

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Bone Research 2022年第2期10卷 326-337页

作者： Xianyi Meng Zhen Lin Shan Cao Iga Janowska Koshiro Sonomoto Darja Andreev Knab Katharina Jinming Wen Karl Xaver Knaup Michael Sean Wiesener Gerhard Krönke Marta Rizzi Georg Schett aline Bozec Department of Internal Medicine 3 Friedrich-Alexander-University Erlangen-Nürnberg(FAU)and Universitätsklinikum ErlangenErlangen 91054Germany Deutsches Zentrum fur Immuntherapie(DYI) Erlangen 91054Germany Department of Rheumatology and Clinical Immunology Faculty of MedicineMedical Center-University of FreiburgFreiburg 79106Germany Department of Internal Medicine 4 Friedrich-Alexander-University Erlangen-Nürnberg(FAU)and Universitätsklinikum ErlangenErlangen 91054Germany

In the bone marrow, B cells and bone-resorbing osteoclasts colocalize and form a specific microenvironment. How B cells functionally influence osteoclasts and bone architecture is poorly understood. Using genetically modified mice and highthroughput analyses, we demonstrate that prolonged HIF-1α signaling in B cells leads to enhanced RANKL production and osteoclast formation. In addition, deletion of HIF-1α in B cells prevents estrogen deficiency-induced bone loss in ***, estrogen controls HIF-1α protein stabilization through HSP70-mediated degradation in bone marrow B *** stabilization of HIF-1α protein in HSP70-deficient bone marrow B cells promotes RANKL production and *** of HSP70 expression by geranylgeranylacetone(GGA) administration alleviates ovariectomy-induced ***, RANKL gene expression has a positive correlation with HIF1 A expression in human B cells. In conclusion, HIF-1αsignaling in B cells is crucial for the control of osteoclastogenesis, and the HSP70/HIF-1α axis may serve as a new therapeutic target for osteoporosis.

关键词： mediated lymphocytes stabilization

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Safety Equipment in Artisanal Maritime Fishing in Gabon: Between Adaptation and the Weight of Socio-Cultural Logics at the Libreville Artisanal Fishing Center (CAPAL)

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Journal of Geoscience and Environment Protection 2023年第5期11卷 86-101页

作者： aline Joëlle Lembe Bekale Léandre Edgard Ndjambou Centre d’Etudes de Recherche en Géosciences Politiques et Prospective (CERGEP) Department of Geography Omar Bongo University Libreville Gabon

Maritime safety equipment allows to prevent and minimize the risks inherent to navigation at sea. However, in the artisanal maritime fishery in Gabon, fishermen are confronted with the major difficulty of the inaccessibility of protective tools to carry out fishing trips in all peace of mind. The absence of equipment to help maritime navigation poses the problem of insecurity in which the various artisanal fishermen work, often victims of numerous accidents at sea. This article aims at highlighting the difficulties of accessibility, by the fishermen, of all the conventional protection tools recommended by the administrations. In fact, the methodology used is based on the consultation of official reports and publications on the subject, field observations and semi-structured interviews with 110 actors. The results obtained reveal, on the one hand, a plethora of conventional protective equipment required of fishing vessels. On the other hand, they reveal the high cost of safety equipment which creates, among the professionals concerned, a reluctance to acquire all of the said tools and forces the interested parties to associate them very often with the traditional procedures for rescue at sea.

关键词： Safety at Sea Artisanal Fishermen Fishing Site Fishing Rites and Traditions

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Monitoring inflammatory bowel disease during pregnancy:Current literature and future challenges

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World Journal of Gastrointestinal Pharmacology and Therapeutics 2018年第1期9卷 1-7页

作者： Tenzin Choden Rohan Mandaliya aline Charabaty Mark C Mattar Department of Internal Medicine MedStar Georgetown University HospitalWashingtonDC 20007United States Division of Gastroenterology MedStar Georgetown University HospitalWashingtonDC 20007United States

Inflammatory bowel disease has a high prevalence in women of childbearing age and can have a significant impact on pregnancy, from conceiving to carrying the pregnancy. Active disease during pregnancy is known to have negative effects on pregnancy outcomes; therefore, careful monitoring during this period is an important but challenging aspect of care and is crucial as it affects important management decisions. Recent data seems to suggest that endoscopy is a relatively safe procedure during all trimesters of pregnancy. Serum biomarkers such as C-reactive protein and fecal calprotectin are helpful non-invasive markers, but have shown conflicting results for correlation with disease activity in some initial studies. Further work is necessary to establish standard of care monitoring during pregnancy.

关键词： Inflammatory bowel disease Crohn’s disease Ulcerative colitis Pregnancy Fecal calprotectin

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Ethylacetate extract of red onion(Allium cepa L.)tunic affects hemodynamic parameters in rats

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Food Science and Human Wellness 2015年第3期4卷 115-122页

作者： Olanrewaju Sam Olayeriju Mary Tolulope Olaleye Olamide Olajusi Crown Kayode Komolafe aline Augusti Boligon Margareth Linde Athayde Akintunde Afolabi Akindahunsi Department of Biochemistry School of SciencesThe Federal University of TechnologyPMB 704AkureNigeria Department of Biochemistry Faculty of ScienceFederal University Oye-EkitiPMB 373Oye-EkitiNigeria Department of Industrial Pharmacy Federal University of Santa Maria97105-900 Santa MariaRSBrazil

The effects of ethylacetate extract of red onion(Allium cepa)tunic(ACTE)on some hemodynamic and biochemical parameters were evaluated in normotensive albino *** pressure parameters were determined in anaesthetized rats orally administered ACTE(10-,20-,or 40 mg/kg)or ramipril(1 mg/kg)once daily for 14 ***,10-,20-,or 40 mg/kg ACTE produced significant(P<0.01),dose-dependent fall in systolic blood pressure,SBP(21%,27%,33%),diastolic blood pressure,DBP(6%,10%,16%),pulse pressure,PP(42%,49%,56%),mean arterial blood pressure,MAPB(13%,18%,23%)and heart rate,HR(4%,5%,7%).The highest effective dose(40 mg/kg)compared well with ramipril(1 mg/kg)with regards to SBP(41%),DBP(19%),PP(70%),MABP(29%)and HR(10%).Similar trends(decreases)were recorded for 40 mg/kg ACTE and ramipril,respectively,as regards the activities of serum enzymes:creatine kinase(60%and 65%),ALT(18%and 14%)and ALP(28%and 16%).HPLC fingerprints of the flavonoid-rich ACTE revealed that flavonols:quercetin,quercitrin,isoquercitrin,rutin and kaempferol are the active *** results demonstrate the hypotensive effect of *** tunic flavonoids initiating further investigation of their individual or synergistic contribution(s)to the observed effects.

关键词： acetate Blood rats

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