检索结果-南通市图书馆

Fractional Order for Food Gums: Modeling and Simulation

在线全文

学校读者我要写书评

暂无评论

Applied Mathematics 2013年第2期4卷 305-309页

作者： Sergio ADavid aline HKatayama Department of Basic Sciences University of Sao PauloSao PauloBrazil

Fractional order calculus can represent systems with high-order dynamics and complex nonlinear phenomena using few coefficients, since the arbitrary order of the derivatives provides an additional degree of freedom to fit a specific behavior. Numerous mathematicians have contributed to the history of fractional calculus by attempting to solve a fundamental problem to the best of their understanding. Each researcher sought a definition and therefore different approaches, which has led to various definitions of differentiation and anti-differentiation of non-integer orders that are proven equivalent. Although all these definitions may be equivalent, from one specific standpoint, i.e., for a specific application, some definitions seem more attractive. Furthermore, it is well known that food gums are complex carbohydrates that can suit for a wide variety of functions in the context of food engineering. The viscoelastic behavior of food gums is crucial for these applications and formulations of new or improved food products. Small progress has been made to understand the viscoelastic behavior of food gums and there are few studies in the literature about these models. In this paper, we applied the Riemann-Liouville approach and the Fourier transform in order to obtain numerical simulations results of a fractional derivative model based on previous literature that to make a quantitative description of the viscoelastic properties behavior for a food gum. The results reveal that the fractional model shows good simulation capability and can be an attractive means for predicting and to elucidate the dynamic viscoelastic behavior of food gums.

关键词： Fractional Calculus Mathematical Model Food Gums Viscoelasticity

Hypericum caprifoliatum and Hypericum connatum affect human trophoblast-like cells differentiation and Ca^(2+) influx

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Biomedicine 2014年第5期4卷 367-373页

作者： aline O.da Conceio Gilsane Lino von Poser Benoit Barbeau Julie Lafond State University of Santa Cruz Federal University of Rio Grande do Sul BioMed Research Center University of Quebec-Montreal Maternal-Fetal Physiology Laboratory Biological Sciences DepartmentUniversity of Quebec-Montreal

Objective:To study the effect of crude methanol and n-hexane extracts of Hypericum connatum(***) and Hypericum caprifoliatum on trophoblast-like ***:BeWo and JEG-3 trophoblast-like cells were submitted to different extract concentrations(1.5,10 and 15 μg/mL) and evaluated in relation to cell viability and in titro trophoblast differentiation and *** viability was evaluated using WST-1 *** was measured by luciferase production,hCG production/release,and mitogenactivated protein kinase signaling pathway *** function of the trophoblast-like cells was measured by^(25)Ca^(2*) influx ***:The results showed a decrease in cell viability/*** plants and different extracts induced a significant decrease in hCG production/release and luciferase *** did not cause mitogen-activated protein kinase signaling pathway disturbance;however,Hypericum caprifoliatum n-hexane extract at 15 μg/mL inhibited extracellular signalregulated kinase 1/2 *** significant increase in Ca^(2+) influx by JEG-3 cells was seen after short and long incubation times with *** methanolie extract at 15 μg/***:The results indicated that these two Hypericum species extracts can interfere on trophoblast differentiation and Ca^(2+)influx,according to their molecular *** in vivo experiments are necessary to establish their action on placental formation and function,this study suggests that attention must be paid to the potential toxic effect of these plants.

关键词： BeWo JEG-3 Hypericaceae ERK1/2 p38 Ca^(2+)influx

Radiographic and tomographic description of marlin sucker Remora osteochir, Pisces: Echeneidae—preliminary data of one specimen

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Marine Life Science & Technology 2020年第3期2卷 246-251页

作者： AndréLuiz Veiga Conrado Renata Stecca lunes Carlos Eduardo Malavasi Bruno aline Tiemi Shiraishi Rocha JoséRoberto Machado Cunha da Silva Laboratory of Evolutive Histophysiology Department of Cell and Developmental BiologyInstitute of Biomedical SciencesUniversity of Sao PauloAvenida ProfLineu Prestes1524Cidade UniversitariaSao Paulo 05508-000Brazil Laboratory of Immunological Techniques Applied to Morphophysiology School of Veterinary Medicine and Animal ScienceDepartment of SurgeryUniversity of Sao PauloAvenida Prof.Di.Orlando Marques de Paiva87.Cidade UniversitariaSao Paulo 05508-270Brazil

Remoras are commensal fish of various marine species,such as sharks,swordfishes,turtles,dolphins,manta rays and *** specimen of marlin sucker Remora osteochir was evaluated using computed tomography for skeletal digital reconstruction,digital radiology for general evaluation and bone counting,and the double contrast technique to distinguish coelomic *** radiographic images,it was possible to observe otoliths in the center of the neurocranium,to count 27 vertebrae,nine pairs of ribs,and to detect the presence of the hipural and epural bones near of the caudal *** double contrast images,it was possible to visualize the swim bladder,gills,heart,liver,stomach and *** the tomographic images and reconstructions,it was possible to identify the intercalar bones of the cephalic disc;the spine with vertebral bodies composed of neural arches and ventral ribs;and the pectoral girdle formed by posttemporal,cleithrum and scapulocoracoid *** was concluded that digital radiology and computed tomography were able to describe anatomical structures of marlin sucker *** without the need for dissection.

关键词： Teleost fish Double contrast Computed tomography Digital radiology Skeleton

Role of urine studies in asymptomatic febrile neutropenic patients presenting to the emergency department

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Emergency Medicine 2021年第2期12卷 99-104页

作者： Hady Zgheib aline El Zakhem Cynthia Wakil Mohamad Ali Cheaito Rola Cheaito Antoine Finianos Ralphe Bou Chebl Rima Kaddoura Nader Al Souky Imad El Majzoub Department of Emergency Medicine American University of Beirut Medical CenterBeirut 11-0236Lebanon Department of Internal Medicine American University of Beirut Medical CenterBeirut 11-0236Lebanon

BACKGROUND: The role of urine studies in the detection of urinary tract infection(UTI) in febrile neutropenic patients with urinary symptoms(having a urinary catheter or having a positive urine analysis) is inarguable. However, the evidence is scarce regarding the indication for urine studies in asymptomatic(i.e., without urinary symptoms) patients with febrile neutropenia(FN) presenting to the emergency department(ED). The aim of this study is to evaluate the need for obtaining urine studies in asymptomatic febrile neutropenic ***: This was a retrospective cohort study conducted on adult cancer patients who presented to the ED with FN and had no urinary symptoms. We included all ED presentations of eligible patients between January 2013 and September 2018. Student's t-test and Wilcoxon rank-sum test were used for continuous data, while Chi-square and Fisher's exact tests were used for categorical data. Participants were divided into two groups based on their urine culture(UC) results: negative and positive UCs. Two cut-offs were used for positive UC results: ≥10~5 cfu/m L and ≥10~4 cfu/m ***: We included 284 patients in our study. The age of our patient population was 48.5±18.5 years. More than two-thirds(68.7%) of patients had severe neutropenia, while only 3.9% and 9.9% of the patients had positive UCs at ≥10~5 cfu/m L and ≥10~4 cfu/m L, respectively. UCs were expectedly positive in most patients with urinalysis(UA) abnormalities. However, 27.3% and 32.1% of patients with positive UCs at ≥10~5 cfu/m L and ≥10~4 cfu/m L respectively had a normal UA. CONCLUSIONS: In our study, the incidence of UTI in adult febrile neutropenic cancer patients who present to the ED without urinary symptoms is low. Consequently, routine urine testing may not be warranted in this population, as it adds unnecessary financial burdens on the patients and delays timely management.

关键词： Adult Cancer Emergency department Febrile neutropenia Urine testing

Recent advances in ultrafast semiconductor disk lasers

在线全文

学校读者我要写书评

暂无评论

Light(Science & Applications) 2015年第1期4卷 281-294页

作者： Bauke W Tilma Mario Mangold Christian A Zaugg Sandro M Link Dominik Waldburger Alexander Klenner aline S Mayer Emilio Gini Matthias Golling Ursula Keller Department of Physics Institute for Quantum ElectronicsETH ZurichZurich 8093Switzerland FIRST Center for Micro-and Nanoscience ETH ZurichZurich 8093Switzerland

The performance of ultrafast semiconductor disk lasers has rapidly advanced in recent *** strong interest from industry for inexpensive,compact,and reliable ultrafast laser sources in the picosecond and femtosecond domains has driven this technology toward commercial *** metrology and biomedical applications would benefit from sub-200-femtosecond pulse durations with peak powers in the kilowatt *** aim of this review is to briefly describe the market potential and give an overview of the current status of mode-locked semiconductor disk *** focus is placed on the ongoing efforts to achieve shorter pulses with higher peak powers.

关键词： lasers modelocked lasers semiconductor lasers ultrafast lasers vertical emitting lasers

<i>Eleutherococcus senticosus</i>: Studies and effects

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Health 2013年第9期5卷 1509-1515页

作者： aline Arouca Dora Maria Grassi-Kassisse Department of Structural and Functional Biology Laboratory of Stress Study Institute of Biology University of Campinas Campinas Brazil

Ginseng is one of the most popular herbal supplements in the world. It is a plant widely used in folk and traditional medicines for cardiovascular, immune, nervous and endocrine systems, and according to the researchers, it has the ability to increase the non-specific resistance state, which characterizes it as an adaptogenic substance. There are different species of ginseng, such as the American, Chinese, Korean and Japanese ginseng;the Korean species (Panax ginseng) is being used for thousands of years as a tonic, prophylactic and “restorative” agent, with powerful antioxidant properties. For a long time, its use was empirical, because people used to believe that it was a panacea that promoted longevity, with beneficial effects for the treatment of physical fatigues. Nowadays, the active components of Eleutherococcus senticosus are well described, however, there are no data on the quantity of a certain class of these secondary compounds produced in each species. Although the Eleutherococcus senticosus extract may contain several substances, including vitamins, minerals, cellulose, and ethanol, the substances responsible for inducing various physiological responses are the eleutherosides (in the root) and ciwujianosides (in the leaf). As Eleutherococcus senticosus receives great attention by showing that its active components can provide protection against oxidative stress, among other benefits, contributing to health and the prevention and treatment of diseases, such as diabetes, cancer, cardiovascular disease and inflammation. The purpose of this article is to describe the main, adverse and toxicological effects of Eleutherococcus senticosus recently related in the literature.

关键词： Eleutherococcus senticosus Ginseng Eleutherosides Ciwujianosides

Far infrared-emitting ceramics decrease Freund's adjuvant-induced inflammatory hyperalgesia in mice through cytokine modulation and activation of peripheral inhibitory neuroreceptors

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Integrative Medicine 2018年第6期16卷 396-403页

作者： Ralph Fernando Rosas aline Armiliato Emer Ana Paula Batisti Daniela Dero Ludtke Bruna Lenfers Turnes Franciane Bobinski Francisco Jose Cidral-Filho daniel fernandes martins Experimental Neuroscience Laboratory(LaNEx) University of Southern Santa CatarinaPalhoca 88137-272Santa CatarinaBrazil Postgraduate Program in Health Sciences University of Southern Santa CatarinaPalhoca 88137-272Santa CatarinaBrazil Laboratory of Bioenergetics and Oxidative Stress(LABOX) Federal University of Santa CatarinaFlorianopolis 88049-000Santa CatarinaBrazil

Objective： The present study aimed to evaluate the analgesic and anti-inflammatory effects of far infrared-emitting ceramics （cFIRs） in a model of persistent inflammatory hyperalgesia and to elucidate the possible mechanisms of these effects. Methods： Mice were injected with complete Freund＇s adjuvant （CFA） and treated with cFIRs via place- ment on a pad impregnated with cFIRs on the bottom of the housing unit for different periods of time. Mice underwent mechanical hyperalgesia and edema assessments, and tumor necrosis factor-α （TNF-α）, interleukin-1β （IL-1β） and IL-10 levels were measured. Twenty-four hours after CFA injection and 30 min before cFIR treatment, mice were pretreated with a nonselective adenosinergic antagonist, caffeine, the selective adenosine receptor A antagonist, 1,3-dipropyl-8-cyclopentylxanthine （DPCPX）, the selective cannabinoid receptor type 1 antagonist, AM281, the selective cannabinoid receptor type 2 antagonist, AM630, or the nonselective opioid receptor antagonist, naloxone, and mechanical hyperalge- sia was assessed. Results： cFIRs statistically （P 〈 0.05） decreased CFA-induced mechanical hyperalgesia （82.86 ±5.21）% in control group vs （56.67±9.54）% in cFIR group） and edema （（1699.0 ± 77.8） gm in control group vs （988.7±107.6） gm in cFIR group）, cFIRs statistically （P 〈 0.05） reduced TNF-α （0.478± 0.072） pg/mg of protein in control group vs （0.273 ±0.055） pg/mg of protein in cFIR group） and IL-113 （（95.81 ± 3.95） pg/mg of protein in control group vs （80.61 ±4.71）pg/mg of protein in cFIR group） levels and statistically （P〈 0.05） increased IL-10 （（18.32 ±0.78） pg/mg of protein in control group vs （25.89 ±1.23） pg/mg of protein in cFIR group） levels in post-CFA-injected paws. Peripheral pre-administration of inhibitory neuroreceptor antagonists （caffeine, DPCPX, AM281, AM630 and naloxone） prevented the analgesic effects of cF1Rs （P 〈 0.05）.Conclusion： These data provide additional support for the use of cFIRs in the treatment of painful in

关键词： Adenosine Cannabinoid Far infrared-emitting ceramics Integrative therapy Inflammatory pain Opioid receptors

Increased basal plasma brain-derived neurotrophic factor levels in sprint runners

在线全文

学校读者我要写书评

暂无评论

Neuroscience Bulletin 2011年第5期27卷 325-329页

作者： Paulo Roberto Correia Fulvio Alexandre Scorza Sérgio Gomes da Silva aline Pansani Michelle Toscano-Silva Antonio Carlos de Almeida Ricardo Mario Arida 圣保罗联邦大学生理学系圣保罗联邦大学神经内外科系 So Joo del-Rei联邦大学实验与计算神经生物学实验室

Objective Exercise is known to enhance circulating brain-derived neurotrophic factor （BDNF） levels in healthy humans. BDNF changes have been measured in endurance but not in strength exercise. The present study aimed to investigate whether anaerobic activity such as sprinting differentially alters basal plasma BDNF concentration. Methods Brazilian sprinters （100 m） at either the international （Olympics and Outdoor World Championships）（n = 14） or the domestic level （n = 8）, and sedentary subjects （n = 15）, were recruited. Plasma BDNF concentrations were analyzed by enzyme-linked immunosorbent assay. Results The basal plasma BDNF concentrations were significantly higher in the international and the domestic sprinters than in the sedentary subjects. In addition, sprinters at the international level had higher plasma BDNF concentrations than those at the domestic level. Conclusion Our findings suggest that increased basal plasma BDNF level is related to enhanced exercise performance.

关键词： brain-derived neurotrophic factor physical exercise sprint plasma brain human

在线全文

学校读者我要写书评

暂无评论

基于FMEA方法的供应链风险管理研究

基于FMEA方法的供应链风险管理研究

作者： aline Uwamahoro 北京交通大学

学位级别：硕士

该研究旨在评估Kabutare区医院的供应链风险管理。作为案例研究的多重耐药结核病面临许多风险。这些风险以多种方式破坏MDR-TB药物的供应,例如其质量,数量和储存条件。本研究旨在利用故障模式和影响分析方法确定MDR-TB供应链管理中的风... 详细信息

该研究旨在评估Kabutare区医院的供应链风险管理。作为案例研究的多重耐药结核病面临许多风险。这些风险以多种方式破坏MDR-TB药物的供应,例如其质量,数量和储存条件。本研究旨在利用故障模式和影响分析方法确定MDR-TB供应链管理中的风险,该方法在许多行业中被广泛用于评估过程的准确性和固有风险。为完成这项研究,社会科学统计软件包(SPSS)被用于分析数据。使用它是因为它提供了全方位的当代描述性统计方法。它还能够以报告和表格格式生成输出。为了提出可以通过使用FMEA(失效模式和效应分析)方法进行的改进,使用ANOVA和多元回归分析。本研究中的数据收集技术采用问卷调查的方法。结果表明,有四种潜在的故障模式具有最主要的风险等级(存储不当,数据输入错误,产品损坏和难以管理库存)。被发现医院专门的药房部门需要改善储存过程并改善服务是合理的,因为他失控并被医院工作人员认为是不可靠的。此外,库存管理无效,他们需要改进现有的存储方法。提出了克服这些问题的建议。

关键词：供应链风险管理多重耐药结核病失效模式和效果分析