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Hybrid coronary revascularization vs. percutaneous coronary interventions for multivessel coronary artery disease

Journal of Geriatric Cardiology 2021年第3期18卷 159-167页

作者： Edward L.Hannan Yi-Feng WU kimberly Cozzens Jacqueline Tamis-Holland Frederick S.k.Ling alice k.jacobs Ferdinand J.Venditti Peter B.Berger Gary Walford Spencer B.kingⅢ University at Albany State University of New YorkAlbanyNYUSA Mount Sinai St.Luke’s Hospital New YorkNYUSA University of Rochester Medical Center RochesterNYUSA Boston Medical Center BostonMAUSA Albany Medical Center AlbanyNYUSA Unaffiliated Johns Hopkins Medical Center Emory Health System AtlantaGAUSA

OBJECTIVE Hybrid coronary revascularization(HCR)combines a minimally invasive surgical approach to the left anterior descending(LAD)artery with percutaneous coronary intervention(PCI)for non-LAD diseased coronary arteries.It is associated with shorter hospital lengths of stay and recovery times than conventional coronary artery bypass surgery,but there is little information comparing it to isolated PCI for multivessel disease.Our objective is to compare long-term outcomes of HCR and PCI for patients with multivessel disease.METHODS This cohort study used data from New York’s cardiac surgery and PCI registries in 2010−2016 to examine mortality and repeat revascularization rates for patients with multivessel coronary artery disease who underwent HCR and PCI.Cox proportional hazards methods were used to reduce selection bias.Patients were followed for a median of four years.RESULTS There was a total of 335 HCR patients(1.2%)and 25,557 PCI patients(98.8%)after exclusions.There was no difference in 6-year risk adjusted survival between HCR and PCI patients 83.17%vs.81.65%,adjusted hazard ratio(aHR)=0.90(95%CI:0.67−1.20).However,HCR patients were more likely to be free from repeat revascularization in the LAD artery(91.13%vs.83.59%,aHR=0.51(95%CI:0.34−0.77)).CONCLUSIONS For patients with multi-vessel coronary artery disease,HCR is rarely performed.There are no differences in mortality rates after four years,but HCR is associated with lower repeat revascularization rates in the LAD artery,presumably due to better longevity in left arterial mammary grafts.

关键词： coronary revascularization mortality

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2007年ACC／AHA非心脏手术围手术期心血管评估与管理指南：实施概要

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麻醉与镇痛 2010年第6期6卷 1-28页

作者： Lee A Fleisher Joshua A Beckman kenneth A Brown Hugh Calkins Elliott Chaikof kirsten E Fleischmann William k Freeman James B Froehlich Edward k kasper Judy R kersten Barbara Riegel John F Robb Sidney C Smith alice k.jacobs Cynthia D Adams Jeffrey L Anderson Elliott M Antman Christopher E Buller Mark A Creager Steven M Ettinger David P Faxon Valentin Fuster Jonathan L Halperin Loren F Hiratzka Sharon A Hunt Bruce W Lytle Rick Nishimura Joseph P Ornato Richard L Page Lynn G Tarkington Clyde W Yancy

美国心脏病学院镁国心脏协会工作组有关实践指南的一份报告（编写委员会对2002年非心脏手术围手术期心血管评估指南的修改）

关键词：非心脏手术管理指南血管评估围手术期 ACC/AHA 美国心脏病学院实践指南心脏协会

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Association and potential mediators between socioeconomic status and childhood obesity in China:findings from a national cohort study

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Global Health Journal 2023年第3期7卷 157-166页

作者： Haixia Zhou Liwang Gao Yang Wu Xiaozhong Wen Wen Peng Na Yan alice Fang Yan Youfa Wang Global Health Institute School of Public HealthXi'an Jiaotong University Health Science CenterXi'anShaanxi 710061China Department of Non-Communicable Disease Management Beijing Children's HospitalCapital Medical UniversityNational Center for Children's HealthBeijing 100045China Department of Sociology Center for Asian&Pacific Economic&SocialDevelopmentResearch Institute for Female CultureJiangxi University of Finance and EconomicsNanchangJiangxi 330032China Division of Behavioral Medicine Department of PediatricsJacobs Schoolof Medicine and Biomedical SciencesState University of New York at BuffaloBuffaloNY 14214USA Nutrition and Health Promotion Center and Department of Public HealthMedical SchoolQinghai UniversityXiningQinghai 810061China Division of Research Patient Care Services Stanford Health CarePalo AltoCA 94305USA

Objective:Socioeconomic status(SES)is associated with childhood obesity,but the underlying factors remain unknown.This study aimed to identify mediators that may explain SES disparities in childhood obesity in China.Methods:Nationally representative longitudinal data from the China Education Panel Survey of 11 o019 children(13.03±0.79)collected from 2013-2014 to 2016-2017 academic years.Overweight/obesity was defined using Chinese national body mass index cut-points.Principal component analysis was used to convert the four SES indicators(maternal and paternal education,and occupation)into one comprehensive variable.Mediation analysis for SES disparities in childhood obesity was conducted using structure equation models.Results:The prevalence of overweight/obesity was 12.8%,and was higher in boys than in girls(17.8%vs.7.6%,Pk(RR)of obesity was 1.23(95%CI:1.09 to 1.40,Pkely to be overweight or obese than girls.SES may impact childhood obesity through birth weight,being the only child in the family and children's self-perceived body weight status in boys,but not in girls.More attention should be made to address childhood obesity in high SES families among boys.Interventions targeting at these mediators are needed.

关键词： Childhood obesity Socioeconomic status Mediators Health disparities

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Multi-Material ALE with AMR for Modeling Hot Plasmas and Cold Fragmenting Materials

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Plasma Science and Technology 2015年第2期17卷 117-128页

作者： alice kONIGES Nathan MASTERS Aaron FISHER David EDER Wangyi LIU Robert ANDERSON David BENSON Andrea BERTOZZI Lawrence Berkeley National Laboratory Lawrence Livermore National Laboratory jacobs School of Engineering 9500 Gilman Dr.UCSDLa JollaCA 92093USA Department of Mathematics 520 Portola PlazaUCLALos AngelesCA 90095USA

We have developed a new 3D multi-physics multi-material code, ALE-AMR, which combines Arbitrary Lagrangian Eulerian （ALE） hydrodynamics with Adaptive Mesh Refinement （AMR） to connect the continuum to the microstructural regimes. The code is unique in its ability to model hot radiating plasmas and cold fragmenting solids. New numerical techniques were developed for many of the physics packages to work efficiently on a dynamically moving and adapting mesh. We use interface reconstruction based on volume fractions of the material components within mixed zones and reconstruct interfaces as needed. This interface reconstruction model is also used for void coalescence and fragmentation. A flexible strength/failure framework allows for pluggable material models, which may require material history arrays to determine the level of accumulated damage or the evolving yield stress in J2 plasticity models. For some applications laser rays are propagating through a virtual composite mesh consisting of the finest resolution representation of the modeled space. A new 2nd order accurate diffusion solver has been implemented for the thermal conduction and radiation transport packages. One application area is the modeling of laser/target effects including debris/shrapnel generation. Other application areas include warm dense matter, EUV lithography, and material wall interactions for fusion devices.

关键词： multi-physics simulations arbitrary lagrangian eulerian hydrodynamics,adaptive mesh refinement fragmentation laser ray tracing NIF

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