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Geoscience frontiers 2020年第6期11卷 2323-2337页

作者： Helen f.Moreira AndréDanderfer alice f.o.costa Samuel M.Bersan Cristiano C.Lana Gláucia N.Queiroga Post Graduate Program of Department of Geology Mine SchoolFederal University of Ouro PretoBrazil Department of Geology Mine SchoolFederal University of Ouro PretoBrazil

Petrological characterization,U-Pb geochronology,Lu-Hf analyses and major and trace element data from mafic intrusions in the Central Espinhaco(central portion of the Brazilian shield)are used here to investigate the geological significance of the Early Neoproterozoic magmatism in the context of the Sao francisco-Congo *** mafic bodies are represented by medium to coarse-grained metagabbros with plagioclase,amphibole and *** U-Pb isotopic data from two samples yielded weighted mean 206pb/238U ages of 895±3.4 Ma(MSWD=1.7)and 896±2.4 Ma(MSWD=0.64),regarded as the best estimates for the crystallization age of these mafic *** and trace element data(including REEs)show that the gabbros originated from a subalkaline tholeiitic magma,typical of intraplate *** rocks are slightly enriched in LREEs and LILEs and depleted in *** new isotope and geochemical data,along with regional knowledge,indicate that these metagabbros mark the beginning of an important Tonian-age extensional tectonic event of the landmass of which the Sao francisco-Congo paleocontinent was part(Rodinia supercontinent or Central African block?).We furthermore suggest that these rocks belong to a prominent suite of Tonian-age mafic rocks that mark a diachronic breakup attempt of this landmass which may have occurred from south to north along the Espinhaco mountain range.

关键词： Mafic rocks Espinhaco basin Sao francisco-Congo paleocontinent Tonian rifting U–Pb geochronology

Environmentally friendly Tannic Acid-furfuryl Alcohol-Soybean Isolate/Casein Composite foams Reinforced with Wood fibers

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Journal of Renewable Materials 2025年第2期13卷 329-347页

作者： Jinxing Li Mustafa Zor Xiaojian Zhou Guanben Du Denis Rodrigue Xiaodong(alice)Wang Department of Wood and forest Sciences Laval UniversityQuébecG1V 0A6Canada Department of Nanotechnology Zonguldak Bülent Ecevit UniversityZonguldak67900Turkey Yunnan Provincial Key Laboratory of Wood Adhesives and Glued Products Southwest Forestry UniversityKunming650224China Department of Chemical Engineering Laval UniversityQuébecG1V 0A6Canada

In this study,two series of foams based on tannic acid(TA),furfuryl alcohol(fA),soybean protein isolate(SPI),and casein(CA),namely TA–fA–SPI(TS series)and TA–fA–CA(TC series)were developed,and their properties were enhanced by adding poplar fibers(Wf).from the samples produced,a complete set of characterization was performed including possible crosslinking reactions,morphology,mechanical properties,flame retardancy,thermal insulation and thermal ***-transform infrared spectroscopy(fTIR)revealed possible covalent crosslinking among the components and hydrogen bonding between Wf and the *** results indicated that lower prepolymer viscosity led to lower apparent density,while Wf addition reduced even more the *** tests showed that the maximum compressive strengths were good,while Wf improved the compressive strength by up to 56%.Scanning electron microscopy(SEM)showed uniform cell structures,but small open pores were ***-dimensional(2D)CT scan images confirmed the good compatibility between Wf and the matrix,with low anisotropy in the *** tests indicated that Wf decreased the pulverization ratio of the materials by up to 42%.Thermogravimetric analysis(TGA)showed good thermal stability of the materials up to 328°*** burning tests showed that the materials were self-extinguishing without residue(dripping).The lowest thermal conductivity was 0.04 W/m·*** results suggest that these novel formaldehyde-free,high biomass content(95%–96%)foams and composite foams have high potential to replace traditional phenolic foams(Pf)in applications such as construction,transportation,packaging,and thermal insulation.

关键词： foam composite tannic acid soybean isolate protein casein poplar fiber compressive strength flame retardancy thermal insulation

Adsorption of Arsenic by Laterite, Sandstone and Shale in a fixed-Bed Column

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Journal of Materials Science and Chemical Engineering 2025年第1期13卷 45-60页

作者： N’Da Akoua alice Koua-Koffi Sandotin Lassina Coulibaly Petemanagnan Jean-Marie ouattara Lacina Coulibaly Agronomic Forestry and Environmental Engineering Department of Environment and Sustainable Development University of Man Man Cte dIvoire Environmental Sciences and Management Laboratory of Environment and Aquatic Biology Nangui Abrogoua University Abidjan Cte dIvoire

The removal of arsenic from water is essential for the protection of public health. To investigate the adsorption capabilities of laterite, sandstone, and shale for the removal of arsenic from aqueous solutions, column experiments were conducted. In this study, raw materials and heat-treated (calcined) materials were examined. The experiments assessed the influence of various parameters, including initial concentration, bed depth, and the effects of heat treatment. The findings revealed that the breakthrough curves were influenced by the initial concentration of arsenic, the depth of the bed, and the type of material used. for an initial arsenic concentration of 5 mg/L, columns containing 85 cm of calcined laterite, sandstone, and shale produced volumes of 7460 ml (1492 min), 3510 ml (702 min), and 4400 ml (880 min) of water with arsenic levels below 0.01 mg/L, respectively. These calcined materials demonstrate significant potential for the effective removal of arsenic from water.

关键词： Geomaterials Adsorption Arsenic Water

Incidence of epiretinal membrane formation following treatment of diabetic retinopathy with panretinal photocoagulation therapy

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International Journal of ophthalmology(English edition) 2025年第3期18卷 449-453页

作者： Patrick Le Michelle Nguyen Karen Lee Thoai Vu Roshan George Maurice BLandersⅢ alice Yang Zhang Department of ophthalmology University of North Carolina at Chapel HillChapel HillNC 27599North CarolinaUSA UT Health San Antonio ophthalmology 7703 Floyd Curl DriveMSC 6230San AntonioTX 78229USA

AIM:To report the incidence of epiretinal membrane(ERM)formation following panretinal photocoagulation(PRP)as the treatment for diabetic retinopathy(DR).METHoDS:Retrospective cross-sectional study of patient charts between January 1st,2010 to January 1st,2017 with at least 1y follow-up *** 809 patients treated with PRP for DR were evaluated for exclusion criteria and 73 eyes remained after exclusion for confounding variables related to ERM formation such as other procedures or *** were determined through medical record review and masked review of optical coherence tomography(oCT)***’s kappa was completed to determine if there was an agreement between masked retinal specialists on oCT *** logistic regression was used to determine the unadjusted odds ratio for patient and procedural characteristics on the formation of *** logistic regression was then completed on select variables that met the cutoff of 0.25 for a statistically significant contribution by the Wald test with the sequential addition of clinical variables that contributed positively to the ***:Among the 73 eyes studied,9.6%formed an ERM with an average time to formation of *** minimum power uses during PRP was found to be statistically significant between non-ERM formers and ERM formers(P=0.044).When adjusting for all selected variables aside from minimum power used,multiple logistic regression determined that for every 10 mW increase in minimum power used during PRP,there is an increase in log odds of 1.009(SE:0.003,P=0.014).CoNCLUSIoN:The incidence of ERM formation in 2y following treatment of DR with PRP is roughly 1 in every 10 eyes treated.

关键词： diabetic retinopathy panretinal photocoagulation epiretinal membranes proliferative diabetic retinopathy

Characterisation of Resistance Potential to Biofilms Microbial Contaminating Thaumatococcus daniellii and Musa paradisiaca Leaves Used as food Packaging

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American Journal of Plant Sciences 2025年第1期16卷 180-194页

作者： Comoé Koffi Donatien Benie N’zebo Désiré Kouame Koua Atobla Yao Paul Attien Wako-Tianwa alice Tuo Adjaratou Traore Noutenin Joelle Diarrassouba Adjehi Dadie Mireille Dosso Department of Biosciences Laboratory of Biotechnology Agriculture and Valorization of Biological Resources University of Flix Houphout Boigny Abidjan Cte dIvoire Department of food Science and Technology Laboratory of Biotechnology and Food Microbiology (LMBM) University of Nangui-Abrogoua Abidjan Cte dIvoire Department of Bacteriology and Virology Institut Pasteur of Cte dIvoire (IPCI) Abidjan Cte dIvoire Department of Biochemistry-Microbiology Laboratory of Agrovalorisation University of Jean Lorougnon GUEDE Daloa Cte dIvoire Department of Medical Sciences University of Alassane Ouattara University Hospital Center (UHC) of Bouak Bouak Cte dIvoire

Despite their biodegradability and economic advantage, plant leaves used as packaging can constitute a public health problem. The aim of this study was to characterize the microbial diversity contaminating plant leaves used as food packaging. In total, two hundred and forty (240) samples composed of Thaumatococcus daniellii and Musa paradisiaca leaves were collected and analyzed. Microbial diversity was assessed using specific medium and biochemical tests. The resistance profile was determined by the Müeller-Hinton agar diffusion method. The resistance (blaSHV, blaIMP, blaTEM) and biofilm formation (pslA, pelA) genes were searched by PCR method. Plant leaves were contaminated by bacterial (68.7%) and fungal (100%) strains. Extreme bacterial (7.1 log10 cfu/cm2) and fungal (3.5 log10 cfu/cm2) loads were obtained on Thaumatococcus daniellii leaves. Bacterial prevalence was 45.1% (S. aureus), 38.8% (E. coli) and 16.1 (P. aeruginosa). In order of decreasing importance, the prevalence of fungal species was 41.1% (A. flavus), 33.1% (A. fumigattus), 13.7% (A. niger) and 12.1% Candida sp. Resistance of E. coli to penicillins ranges from 31.6% to 87.3% and to cephalosporins from 13.3% to 28%. The P. aeruginosa strains were mainly resistant to aztreonam (87.6%). Those of S. aureus showed resistance to tetracycline (67.6), vancomycin (53), erythromycin (44.6) and levofloxacin (32.7). The blaSHV (14.28% to 18.60%) and blaIMP (9.52% to 16.28%) genes were detected in the bacterial strains. P. aeruginosa strains (19.05%) harbored the pslA and pelA genes. The health safety of these biodegradable plant-based packaging contributes to their valorization.

关键词： Resistance Biofilm Genes Thaumatococcus daniellii Musa paradisiaca

Establishment of customized mouse stem cell lines by sequential nuclear transfer

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Cell Research 2007年第1期17卷 80-87页

作者： alice Jouneau fRE 2857 Biologie du Développement et Reproduction UMR 1198 ENVA CNRS f-78350 INRA Chinese Academv of Sciences Jouy en Josas Beijing 100080 france State Key Laboratory of Reproductive BiologyJoint laboratory of biology of embryonic cells of mammalians(LABIoCEM) Institute of Zoology China

Therapeutic cloning,whereby embryonic stem cells (ESCs) are derived from nuclear transfer (NT) embryos,mayplay a major role in the new era of regenerative *** this study we established forty nuclear transfer-ESC (NT-ESC) lines that were derived from NT embryos of different donor cell types or *** found that NT-ESCs werecapable of forming embryoid bodies,In addition,NT-ESCs expressed pluripotency stem cell markers in vitro and coulddifferentiate into embryonic tissues in *** embryos from early passage R1 donor cells were able to form full termdeveloped pups,whereas those from late passage R1 ES donor cells lost the potential for reprogramming that is essentialfor live *** subsequently established sequential NT-R1-ESC lines that were developed from NT blastocyst of latepassage R1 ESC ***,these NT-R1-ESC lines,when used as nuclear transfer donors at their early passages,failed to result in live *** indicates that the therapeutic cloning process using sequential NT-ESCs may not rescuethe developmental deficiencies that resided in previous donor generations.

关键词： nuclear transfer therapeutic cloning embryonic stem cells

Deciphering the epitranscriptome： A green perspective

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Journal of Integrative Plant Biology 2016年第10期58卷 822-835页

作者： alice Burgess School of Biological Sciences The University of Adelaide South Australia 5005 Australia School of Agriculture Food and Wine The WaiteResearch Institute The University of Adelaide South Australia 5005 Australia The University of Adelaide and Shanghai Jiao Tong University Joint International Centre for Agriculture and Health Joint International Research Laboratory of Metabolic & Developmental Sciences AdelaideAustralia

The advent of high-throughput sequencing technol- ogies coupled with new detection methods of RNA modifica- tions has enabled investigation of a new layer of gene regulation - the epitranscriptome. With over loo known RNA modifications, understanding the repertoire of RNA modifications is a huge undertaking. This review summarizes what is known about RNA modifications with an emphasis on discoveries in plants. RNA ribose modifications, base methyl- ations and pseudouridylation are required for normal develop- ment in Arabidopsis, as mutations in the enzymes modifying them have diverse effects on plant development and stress responses. These modifications can regulate RNA structure, turnover and translation. Transfer RNA and ribosomal RNA modifications have been mapped extensively and their functions investigated in many organisms, including plants. Recent work exploring the locations, functions and targeting of N6-methyladenosine （m^6A）, 5-methylcytosine （m^5C）, pseudour- idine （up）, and additional modifications in mRNAs and ncRNAs are highlighted, as well as those previously known on tRNAs and rRNAs. Many questions remain as to the exact mechanisms of targeting and functions of specific modified sites and whether these modifications have distinct functions in the different classes of RNAs.

关键词： RNA modifications epitranscriptome RNA 5-methylcytosine (m^5C) N^6-methyladenosine (m^6A) Pseudouridine (φ) Arabidopsis

African Americans are less likely to receive curative treatment for hepatocellular carcinoma

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World Journal of Hepatology 2018年第11期10卷 849-855页

作者： Lindsay A Sobotka alice Hinton Lanla f Conteh Department of Internal Medicine The Ohio State University Wexner Medical Center Division of Biostatistics College of Public Health The Ohio State University Department of Gastroenterology and Hepatology The Ohio State Wexner Medical Center

AIM To determine if racial disparities continue to exist in the treatment of hepatocellular carcinoma(HCC).METHoDS A retrospective database analysis using the Nationwide Inpatient Sample was performed including patients with a primary diagnosis of HCC. Univariate and multivariate analyses were utilized to determine racial disparities in liver decompensation, treatment, inpatient mortality, and metastatic *** A total of 62604 patients with HCC were included consisting of 32428 Caucasian, 9726 African-American, 8988 Hispanic, and 11462 patients of other races. Caucasian patients were more likely to undergo curative therapies of liver transplant(oR: 2.66, 95%CI: 1.92-3.68), resection(oR: 1.82, 95%CI: 1.48-2.23), and ablation(oR: 1.77, 95%CI: 1.36-2.30) than African-American patients. Hispanic patients were more likely to undergo transplant(oR: 2.18, 95%CI: 1.40-3.39) and ablation(oR: 1.46, 95%CI:1.05-2.03) than African-American patients. Patients of other races were more likely to receive a liver transplant(oR: 2.41, 95%CI: 1.62-3.61), resection(oR: 1.79 95%CI: 1.39-2.32), and ablation(oR: 2.03, 95%CI: 1.47-2.80) than African-American patients. There are no differences in the rates of transarterial chemoembolization between *** Racial disparities in HCC treatment exist despite emphasis to support equality in healthcare. African-American patients are less likely to undergo curative treatments for HCC.

关键词： Racial disparity Hepatocellular carcinoma Liver transplantation Resection Ablation

Paleoproterozoic juvenile magmatism within the northeastern sector of the Sao francisco paleocontinent:Insights from the shoshonitic high Ba-Sr Montezuma granitoids

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Geoscience frontiers 2020年第5期11卷 1821-1840页

作者： Samuel Moreira Bersan alice fernanda de oliveira costa Andre Danderfer francisco Roberio de Abreu Cristiano Lana Glaucia Queiroga Craig Storey Hugo Moreira Universidade federal de ouro Preto Programa de Pos-graduacaoDepartamento de GeologiaCampus Morro do CruzeiroOuro PretoMGCEP 35400-000Brazil Universidade federal de ouro Preto Departamento de GeologiaCampus Morro do CruzeiroOuro PretoMGCEP 35400-000Brazil Sustain Geologia Ltda Teresa M.Valadares 503/502Belo HorizonteMGCEP 30575-160Brazil University of Portsmouth School of Earth and Environmental SciencesBurnaby BuildingBurnaby RoadPortsmouthPO13QLUK

New,integrated petrographic,mineral chemistry,whole rock geochemical,zircon and titanite UPb geochronology,and zircon Hf isotopic data from the Montezuma granitoids,as well as new geochemical results for its host rocks represented by the Corrego Tingui Complex,provides new insights into the late-to post-collisional evolution of the northeastern Sao francisco paleocontinent.U-Pb zircon dates from the Montezuma granitoids spread along the Concordia between ca.2.2 Ga to 1.8 Ga and comprise distinct *** I have crystallization ages between ca.2.15 Ga and 2.05 Ga and are interpreted as inherited *** II zircon dates vary from 2.04 Ga to1.9 Ga and corresponds to the crystallization of the Montezuma granitoids,which were constrained at ca.2.03 Ga by the titanite U-Pb *** age zoning is common within the ca.1.8 Ga Group III zircon ages,being related to fluid isotopic re-setting during the Espinhaco rifiting ***εHf(t)analysis show dominantly positive values for both Group I(-4 to+9)andⅡ(-3 to+8)zircons and TDM2 model ages of 2.7-2.1 Ga and 2.5-1.95 Ga,***,the Montezuma granitoids are weakly peraluminous to metaluminous magnesian granitoids,enriched in LILES and LREE,with high to moderate Mg#and depleted in some of the *** lithochemical signature,added to the juvenile signature of both inherited and crystallized zircons,allowed its classification as a shoshonitic high Ba-Sr granitoid related to a late-to post-collisional lithosphere delamination followed by asthenospheric *** this scenario,the partial melting of the lithospheric mantle interacted with the roots of an accreted juvenile intra-oceanic arc,being these hybrid magma interpreted as the source of the Montezuma *** Corrego Tingui Complex host rocks are akin to a syn-to late-collisional volcanic arc granitoids originated from the partial melting of ancient crustal *** results presented in this study have revealed the occurrence of j

关键词： Zircon U–Pb-Hf Titanite U–Pb High Ba–Sr Late-to post-collisional Sao francisco paleocontinent

Challenges in developing therapeutic strategies for mild neonatal encephalopathy

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Neural Regeneration Research 2022年第2期17卷 277-282页

作者： alice McDouall Guido Wassink Laura Bennet Alistair J.Gunn Joanne o.Davidson Department of Physiology The University of AucklandAucklandNew Zealand

There is increasing evidence that infants with mild neonatal encephalopathy(NE) have significant risks of mortality, brain injury and adverse neurodevelopmental outcomes. In the era of therapeutic hypothermia, infants need to be diagnosed within 6 hours of birth, corresponding with the window of opportunity for treatment of moderate to severe NE, compared to the retrospective grading over 2 to 3 days, typically with imaging and formal electroencephalographic assessment in the pre-hypothermia era. This shift in diagnosis may have increased the apparent prevalence of brain damage and poor neurological outcomes seen in infants with mild NE in the era of hypothermia. Abnormal short term outcomes observed in infants with mild NE include seizures, abnormal neurologic examination at discharge, abnormal brain magnetic resonance imaging and difficulty feeding. At 2 to 3 years of age, mild NE has been associated with an increased risk of autism, language and cognitive deficits. There are no approved treatment strategies for these infants as they were not included in the initial randomized controlled trials for therapeutic hypothermia. However, there is already therapeutic creep, with many centers treating infants with mild NE despite the limited evidence for its safety and efficacy. The optimal duration of treatment and therapeutic window of opportunity for effective treatment need to be specifically established for mild NE as the evolution of injury is likely to be slower, based on preclinical data. Randomized controlled trials of therapeutic hypothermia for infants with mild NE are urgently required to establish the safety and efficacy of treatment. This review will examine the evidence for adverse outcomes after mild NE and dissect some of the challenges in developing therapeutic strategies for mild NE, before analyzing the evidence for therapeutic hypothermia and other strategies for treatment of these infants.

关键词： asphyxia electroencephalogram erythropoietin mild hypoxic ischemic encephalopathy neonatal encephalopathy neurological examination neuroprotection Sarnat score therapeutic hypothermia