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Asian Journal of Urology 2024年第1期11卷 26-32页

作者： Awad Elsid Osman Sahar Alharbi Atif ali Ahmed Asim ali Elbagir Pathology and Clinical Laboratory Management Department(PCLM) King Fahad Medical CityRiyadhSaudi Arabia Department of Pathology and Laboratory Medicine University of Missouri at Children's Mercy HospitalKansas CityMOUSA

Objective: Genome-wide association studies have demonstrated that single nucleotide polymorphisms (SNPs) are important risk factors for the development of prostate cancer (PCa). Preliminary studies have suggested that the incidence of PCa in Saudi males is low but is probably familial or genetically ***: To identify any possible association of SNP with PCa development in Saudi patients, we investigated a group of SNPs in Saudi PCa patients (n=85) and compared the outcomes to healthy normal controls (n=115) and nodular hyperplasia patients (n=120). DNA was extracted from paraffin-embedded formalin fixed tissue or whole blood from both patients’ groups and healthy control group. A total of thirteen SNPs were genotyped using TaqMan® minor groove binder polymerase chain reaction ***: The rs16901979A, s629242T and rs1447295A alleles were found at significantly higher frequency in PCa patients than controls (p< 0.05). The rs16901979 CA genotype was found at significantly greater frequency in PCa patients than in healthy controls (43% vs. 14%, odds ratio=4.6, p=0.0001) and benign hyperplasia group (43% vs. 25%, odds ratio=2.2, p=0.009).Conclusion: Our study has highlighted the association of rs16901979 SNP with PCa in Saudi males. Such findings have important implications in the PCa diagnosis and in screening unaffected family members of Saudi patients.

关键词： Prostatecancer Saudi Singlenucleotide polymorphism Allele

Evolution of light deflection and shadow from a gauge-potential-like AdS black hole under the influence of a non-magnetic plasma medium

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Communications in Theoretical Physics 2024年第9期76卷 85-96页

作者： Riasat ali Xia Tiecheng Muhammad Awais Rimsha Babar Department of Mathematics Shanghai University and Newtouch Center for Mathematics of Shanghai University Department of Mathematics University of Engineering and Technology Department of Mathematics GC University Faisalabad Layyah Campus

We investigate the light deflection in the weak field approximation from the accelerating charged AdS black hole. For this purpose, we apply the Gauss–Bonnet theorem to calculate the light deflection in the weak field area and use the Gibbons–Werner approach to analyze the optical geometry of the accelerating charged AdS black hole in the non-magnetic plasma absence/presence of a non-magnetic medium. We also represent the graphical behavior of the light deflection angle w.r.t. the impact parameter. We also compute the light deflection angle using Keeton and Petters approximations under the impact of accelerating charged AdS black hole geometry. Furthermore, by using the ray-tracing approach, we determine the shadow in the nonmagnetic plasma presence and also demonstrate that graphical shadow has an impact on the gauge potential, non-magnetic plasma frequencies and charge.

关键词： accelerating charged AdS black hole deflection angle Gibbons-Werner approach ray-tracing approach shadow

Development of anti-corrosive coating on AZ31 Mg alloy modified by MOF/LDH/PEO hybrids

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Journal of Magnesium and Alloys 2024年第2期12卷 586-607页

作者： Muhammad ali Khan Ananda Repycha Safira Mohammad Aadil Mosab Kaseem Corrosion and Electrochemistry Laboratory Department of Nanotechnology and Advanced Materials EngineeringSejong UniversitySeoul 05006Republic of Korea

The self-assembly of hybrid inorganic-organic materials on stationary platforms plays a critical role in improving their structural stability and wide *** this work,a novel two-step hydrothermal approach is proposed for synthesizing stable and advanced hybrid coatings on metal-oxide platforms through the surface modification of layered double hydroxide(LDH)films using novel metal-organic frameworks(MOFs).Initially,Mg-Al LDH nanocontainers,grown on a magnesium oxide layer produced through plasma electrolytic oxidation(PEO)of AZ31 Mg alloy substrate,were intercalated with cobalt via an oxidation route,providing the metallic coordination center for the MOF *** the subsequent step,a pioneering technique is introduced,utilizing tryptophan as the organic linker for the first time at a pH of *** self-assembly of cobalt-tryptophan complex,driven by the strong bonding between electrophilic sites of monomers and nucleophilic sites,facilitated the formation of a MOF network having a cloud-like structure on the surface of MgAl LDH's *** resulting MOF-LDH encapsulation containers demonstrate exceptional electrochemical stability when exposed to a 3.5 wt.%NaCl solution,surpassing the performance of PEO and pure LDH *** enhanced stability is attributed to the development of a dense top layer and a stable composition within the self-assembled MOF,effectively sealing flaws and preventing the infiltration of corrosive ions into the underlying metallic *** formation mechanism of MOFs on LDH galleries is investigated using density functional theory calculations.

关键词： Mg alloy Layered double hydroxide Metal-organic frameworks Corrosion DFT

CRISPR,CAR-T,and NK:Current applications and future perspectives

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Genes & Diseases 2024年第4期11卷 246-257页

作者： Mohadeseh Khoshandam Hossein Soltaninejad Amir ali Hamidieh Saman Hosseinkhani Department of Reproductive Biology Academic Center for EducationCultureand Research(ACECR)Qom branch***Iran National Institute of Genetic Engineering and Biotechnology(NIGEB) Tehran 14965/161Iran Department of stem cells technology and Tissue Regeneration Faculty of Interdisciplinary Science and TechnologiesTarbiat Modares UniversityTehran 15614Iran Pediatric Cell Therapy and Gene Therapy Research Center GeneCell&Tissue Research InstituteTehran University of Medical SciencesTehran ***Iran Department of Biochemistry Faculty of Biological SciencesTarbiat Modares UniversityTehran 15614Iran

Chimeric antigen receptor T(CAR-T)cell therapy represents a breakthrough in personalized cancer *** this regard,synthetic receptors comprised of antigen recognition domains,signaling,and stimulatory domains are used to reprogram T-cells to target tum or cells and destroy *** the success of this approach in refractory B-cell malignancies,the optimal potency of CAR T-cell therapy for many other cancers,particularly solid tumors,has not been *** killer cells are powerful cytotoxic lymphocytes specialized in recognizing and dispensing the tumor cells in coordination with other anti-tumor immunity *** on these studies,many investigations are focused on the accurate designing of CAR T-cells with clustered regularly interspaced short palindromic repeats(CRISPR)/CRISPR-associated protein 9(Cas9)system or other novel gene editing tools that can induce hereditary changes with or without the presence of a double-stranded break into the *** methodologies can be specifically focused on negative controllers of T-cells,induce modifications to a particular gene,and produce reproducible,safe,and powerful allogeneic CAR T-cells for on-demand cancer *** improvement of the CRISPR/Cas9 innovation offers an adaptable and proficient gene-editing capability in activating different pathways to help natural killer cells interact with novel CARs to particularly target tumor *** achievements and future challenges of combining next-generation CRISPR-Cas9 gene editing tools to optimize CAR T-cell and natural killer cell treatment for future clinical trials toward the foundation of modern cancer treatments have been assessed inthis review.

关键词： Cancer CAR T-cell CRISPR Gene editing Immunotherapy NK cell

Fully polarized Compton scattering in plane waves and its polarization transfer

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Matter and Radiation at Extremes 2024年第3期9卷 45-56页

作者： Suo Tang Yu Xin Meng Wen Mamat ali Bake Baisong Xie College of Physics and Optoelectronic Engineering Ocean University of ChinaQingdaoShandong 266100China Department of Physics Hubei UniversityWuhan 430062China Xinjiang Key Laboratory of Solid State Physics and Devices School of Physics Science and TechnologyXinjiang UniversityUrumqi 830017China Key Laboratory of Beam Technology of the Ministry of Education and College of Nuclear Science and TechnologyBeijing Normal UniversityBeijing 100875China

Fully polarized Compton scattering from a beam of spin-polarized electrons is investigated in plane-wave backgrounds in a broad intensity region from the perturbative to the nonperturbative *** the perturbative regime,polarized linear Compton scattering is considered for investigating polarization transfer from a single laser photon to a scattered photon,and in the high-intensity region,the polarized locally monochromatic approximation and locally constant field approximation are established and are employed to study polarization transfer from an incoming electron to a scattered *** numerical results suggest an appreciable improvement of about 10%in the scattering probability in the intermediate-intensity region if the electron’s longitudinal spin is parallel to the laser *** longitudinal spin of the incoming electron can be transferred to the scattered photon with an efficiency that increases with laser intensity and collisional *** collision between an optical laser with frequency1 eV and a 10 GeV electron,this polarization transfer efficiency can increase from about 20%in the perturbative regime to about 50%in the nonperturbative regime for scattered photons with relatively high energy.

关键词： polarized scattered transfer

Balancing Exploration–Exploitation of Multi-verse Optimizer for Parameter Extraction on Photovoltaic Models

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Journal of Bionic Engineering 2024年第2期21卷 1022-1054页

作者： Yan Han Weibin Chen ali Asghar Heidari Huiling Chen Xin Zhang College of Computer Science and Artificial Intelligence Wenzhou UniversityWenzhou325035China School of Surveying and Geospatial Engineering College of EngineeringUniversity of TehranTehranIran School of Biomedical Engineering National Engineering Research Center of Ophthalmology and OptometryEye HospitalWenzhou Medical UniversityWenzhou325027China Key Lab of Biohealth Materials and Chemistry of Wenzhou Wenzhou UniversityWenzhouChina Key Laboratory of Intelligent Informatics for Safety&Emergency of Zhejiang Province Wenzhou UniversityWenzhouChina

Extracting photovoltaic(PV)model parameters based on the measured voltage and current information is crucial in the simulation and management of PV *** accurately and reliably extract the unknown parameters of different PV models,this paper proposes an improved multi-verse optimizer that integrates an iterative chaos map and the Nelder–Mead simplex method,*** experiments verified that the proposed INMVO fueled by both mechanisms has more affluent populations and a more reasonable balance between exploration and ***,to verify the feasibility and competitiveness of the proposal,this paper employed INMVO to extract the unknown parameters on single-diode,double-diode,three-diode,and PV module four well-known PV models,and the high-performance techniques are selected for *** addition,the Wilcoxon signed-rank and Friedman tests were employed to test the experimental results *** evaluation metrics,such as root means square error,relative error,absolute error,and statistical test,demonstrate that the proposed INMVO works effectively and accurately to extract the unknown parameters on different PV models compared to other *** addition,the capability of INMVO to stably and accurately extract unknown parameters was also verified on three commercial PV modules under different irradiance and *** conclusion,the proposal in this paper can be implemented as an advanced and reliable tool for extracting the unknown parameters of different PV *** that the source code of INMVO is available at https://***/woniuzuioupao/INMVO.

关键词： Photovoltaic models Multi-verse optimizer Nelder-Mead simplex Iterative chaos map

Congenital absence of the lateral meniscus:A case report

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World Journal of Orthopedics 2024年第5期15卷 477-482页

作者： Hamad ali Alkhunayfir Abdulaziz ali AlQahtani Abdulrahman Jalwi Korkoman Department of Orthopedic Surgery Prince Muhammed bin Abdulaziz HospitalRiyadh 61422Saudi Arabia Department of Orthopedic Surgery Prince Sultan Military Medical CityRiyadh 12233Saudi Arabia Department of Orthopedic Surgery University of BishaBisha 67714Saudi Arabia

BACKGROUND Congenital absence of the menisci is a rare anatomical variation characterized by the absence or underdevelopment of one or both menisci in the knee *** menisci are crucial in load distribution,joint stability,and shock *** the clinical presentation,diagnosis,and management of this condition is important for optimal patient *** SUMMARY A 27-year-old male with a long-standing history of knee pain underwent diagnostic arthroscopy,revealing a congenital absence of the *** patient's clinical findings,imaging results,surgical procedures,and pertinent images are *** case presents a unique aspect with the congenital absence of the meniscus,contributing valuable insights to the literature on rare anatomical *** This case of congenital absence of the menisci highlights the diagnostic challenges posed by rare *** diagnostic arthroscopy played a crucial role in identifying the absence of the meniscus and providing an explanation for the patient's persistent knee *** case underscores the importance of individualized treatment approaches,including physical therapy,for optimal management of rare meniscal *** research is warranted to explore effective management strategies for the aforementioned cases and to expand our knowledge of these rare conditions.

关键词： Lateral meniscus Arthroscopy Knee joint Menisci reformation Magnetic resonance imaging Case report

Soliton solutions for nonlinear variable-order fractional Korteweg-de Vries(KdV)equation arising in shallow water waves

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Journal of Ocean Engineering and Science 2024年第1期9卷 50-58页

作者： Umair ali Hijaz Ahmad Hanaa Abu-Zinadah Department of Applied Mathematics and Statistics Institute of Space TechnologyP.O.Box 2750Islamabad 44000Pakistan Near East University Operational Research Center in HealthcareNear East BoulevardPC:99138 Nicosia/Mersin 10Turkey Section of Mathematics International Telematic University UninettunoCorso Vittorio Emanuele II3900186 RomaItaly University of Jeddah College of ScienceDepartment of StatisticsJeddahSaudi Arabia

Nonlinear fractional differential equations provide suitable models to describe real-world phenomena and many fractional derivatives are varying with time and *** present study considers the advanced and broad spectrum of the nonlinear(NL)variable-order fractional differential equation(VO-FDE)in sense of VO Caputo fractional derivative(CFD)to describe the physical *** VO-FDE transforms into an ordinary differential equation(ODE)and then solving by the modified(G/G)-expansion *** ac-curacy,the space-time VO fractional Korteweg-de Vries(KdV)equation is solved by the proposed method and obtained some new types of periodic wave,singular,and Kink exact *** newly obtained solutions confirmed that the proposed method is well-ordered and capable implement to find a class of NL-VO *** VO non-integer performance of the solutions is studied broadly by using 2D and 3D graphical *** results revealed that the NL VO-FDEs are highly active,functional and convenient in explaining the problems in scientific physics.

关键词： Space-time VO fractional KdV equation modiﬁed(G′/G)-expansion method VO Caputo fractional derivative generalized Riccati equation

5G Resource Allocation Using Feature Selection and Greylag Goose Optimization Algorithm

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Computers, Materials & Continua 2024年第7期80卷 1179-1201页

作者： Amel ali Alhussan S.K.Towfek Department of Computer Sciences College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Computer Science and Intelligent Systems Research Center BlacksburgVA 24060USA

In the contemporary world of highly efficient technological development,fifth-generation technology(5G)is seen as a vital step forward with theoretical maximum download speeds of up to twenty gigabits per second(Gbps).As far as the current implementations are concerned,they are at the level of slightly below 1 Gbps,but this allowed a great leap forward from fourth generation technology(4G),as well as enabling significantly reduced latency,making 5G an absolute necessity for applications such as gaming,virtual conferencing,and other interactive electronic *** of this change are not limited to connectivity alone;it urges operators to refine their business strategies and offers users better and improved digital *** essential factor is optimization and the application of artificial intelligence throughout the general arrangement of intricate and detailed 5G *** Binary Greylag Goose Optimization(bGGO)to achieve a significant reduction in the feature set while maintaining or improving model performance,leading to more efficient and effective 5G network management,and Greylag Goose Optimization(GGO)increases the efficiency of the machine ***,the model performs and yields more accurate *** work proposes a new method to schedule the resources in the next generation,5G,based on a feature selection using GGO and a regression model that is an ensemble of K-Nearest Neighbors(KNN),Gradient Boosting,and Extra Trees *** ensemble model shows better prediction performance with the coefficient of determination R squared value equal *** proposed framework is supported by several Statistical analyses,such as theWilcoxon signed-rank *** of the benefits of this study are the introduction of new efficient optimization algorithms,the selection of features and more reliable ensemble models which improve the efficiency of 5G technology.

关键词： Optimization ensemble learning 5G technology artificial intelligence greylag goose optimization ANOVA test

Enhanced electrochemical and photocatalytic performance achieved through dual incorporation of SnO_(2)and WO_(3)nanoparticles into LDH layer fabricated on PEO-coated AZ31 Mg alloy

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Journal of Magnesium and Alloys 2024年第5期12卷 1880-1898页

作者： Muhammad ali Khan Ananda Repycha Safira Mosab Kaseem Arash Fattah-alhosseini Corrosion and Electrochemistry Laboratory Department of Nanotechnology and Advanced Materials EngineeringSejong UniversitySeoul 05006Republic of Korea Department of Materials Engineering Faculty of EngineeringBu-Ali Sina UniversityHamedanIran

This study explores the potential of LDH flakes decorated with metallic oxide nanoparticles to function as both anti-corrosion barriers against chloride anions and heterogeneous photocatalysts for tetracycline degradation under visible *** process involves modifying the primarily MgO-based inorganic porous film by growing a MgFe LDH film,followed by the individual and dual incorporation of SnO_(2)and WO_(3)*** dual incorporation of these nanoparticles into the LDH matrix leads to synergistic interactions,effectively sealing pre-existing defects within LDH flakes and facilitating the in-situ formation of catalytic sites through oxidation and the induction of surface oxygen vacancy defects,which synergistically contribute to the enhancement of both electrochemical and photocatalytic *** enhanced electrochemical stability is reflected in a significant reduction in corrosion current density by 4 orders of magnitude compared to unmodified porous ***,the decorated film demonstrates sustained photocatalytic functionality,achieving significant degradation(95.5%)of tetracycline within two *** study presents a novel approach,highlighting the dual effectiveness of LDHs decorated by dual metal oxides as an anti-corrosive agent and photocatalyst,with promising implications for environmental remediation and wastewater purification.

关键词： Porous film LDH film Anti corrosive Photocatalysis Oxygen vacancy Tetracycline