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Single-Bit Comparator in Quantum-Dot Cellular Automata (QCA) Technology Using Novel QCAXNOR Gates

Journal of Electronic Science and Technology 2021年第3期19卷 263-273页

作者： ali hussien majeed Mohd Shamian Zainal Esam Alkaldy Danial Md.NorNor Department of Electrical Engineering University of KufaNajaf 54003 Department of Electrical Engineering Technology Universiti Tun Hussein Onn MalaysiaParit Raja 86400

To fill the continuous needs for faster processing elements with less power consumption causes large pressure on the complementary metal oxide semiconductor(CMOS)technology *** scaling scenario is not an option nowadays and other technologies need to be *** quantum-dot cellular automata(QCA)technology is one of the important emerging nanotechnologies that have attracted much researchers’attention in recent *** technology has many interesting features,such as high speed,low power consumption,and small *** features make it an appropriate alternative to the CMOS *** paper suggests three novel structures of XNOR gates in the QCA *** presented structures do not follow the conventional approaches to the logic gates design but depend on the inherent capabilities of the new *** proposed structures are used as the main building blocks for a single-bit *** resulted circuits are simulated for the verification purpose and then compared with existing counterparts in the *** comparison results are encouraging to append the proposed structures to the library of QCA gates.

关键词： Nanotechnology quantum-dot cellular automata(QCA) QCA comparator XNOR gate XOR gate

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Angiogenesis Factors Associated with New Breast Cancer Cell Line AMJ13 Cultured <i>in Vitro</i>

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Advances in Breast Cancer Research 2015年第4期4卷 100-108页

作者： Ahmed majeed Al-Shammari Worod Jawad Kadhim Allak Mahfoodha Umran Nahi Y. Yaseen Ayman hussien Experimental Therapy Department Iraqi Center for Cancer and Medical Genetic Research Al-Mustansiriyah University Baghdad Iraq Biotechnology Department Collage of Science Baghdad University Baghdad Iraq

Background: AMJ13 is a new breast cancer cell line that has been established from a 70-year-old Iraqi woman with a histological diagnosis of infiltrating ductal carcinoma. It is the first for an Iraqi population. In breast cancer, angiogenesis provides the tumor tissue, which is rapidly proliferated with oxygen and nutrients, removes wastes and increases the opportunity of cancer cells to invade other organs. Methods: The AMJ13 breast cancer cell line was represented at three different passages and incubated for interval times. Microarray panel of 43 different angiogenesis markers was used to scan the supernatant for the factors. ELISA was used to quantify some of the important angiogenesis factors released in the culture medium and to confirm absence of those who was not detected by the antibody array. RT-PCR was used to confirm the gene expression (mRNA) of studied factors. Results: Microarray analysis showed that TIMP1 and two secreted at highest levels compared to the rest of the factors with low presence of endostatin. Other non-detectable factors by microarray examined by ELISA assay that showed highest expression level of VEGF-A were obtained at earliest passage, while the highest levels of FGF-b were obtained at late passage. The VEGF-D secretion was shown low concentrations at all studied passages. There is no detectable level of EGF protein in different passages and times interval tested. There are no significant differences in secretion of sICAM between different passages and incubation periods. Conclusion is that AMJ13 cell line depends on VEGF-A as main angiogenesis factor to induce micro-vessels supported by low levels of VEGF-D for lymphatic vessels formation. AMJ13 cell line depends on FGF as growth factors as in late passages it was shifted to depend mainly on FGF completely. All of this process may be regulated by TGF-β. TIMP-1 has proangiogentic effect and has feedback talk with TIMP-2. Understanding the angiogenesis process for breast cancer can

关键词： Angiogenesis Factors Breast Cancer Cell AMJ13 Tumor Tissue

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