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Lumbar Artery Pseudo-Aneurysm after Spinal Trauma and Transpedicular Fixation: A Case Report

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Open Journal of Modern Neurosurgery 2021年第2期11卷 65-72页

作者： Armel Junior Tokpo Guelord Metre Mpambia Fayçal Lakhdar hassan Amadou ali Oualid Mohammed Hmamouche Mohammed Benzagmout Khalid Chakour Mohammed El Faiz Chaoui Teaching Hospital of hassan 2 Fès Morocco

Introduction: A case of lumbar artery pseudo-aneurysm after surgery for lumbar vertebra burst fracture is presented. Only two cases secondary to spinal trauma and revealed after surgery have been described in the literature. A review of literature was conducted and a possible relationship with burst fracture or reduction maneuvers was discussed. Case Presentation: Here, we report a post traumatic lumbar burst facture with incomplete motor deficit of lower limbs after a fall. Surgical reduction and stabilization via posterior approach were performed. Post-operatively, a hemorrhage through surgical wound had been noticed. Pseudo-aneurysm of the lumbar artery at L3 level was diagnosed and embolisation was performed. Conclusion: This is a rare case of pseudo-aneurysm occurring in the setting of surgical stabilisation after a trauma. It was revealed by a hemorrhage discovered as a late complication. We should be aware of such potential complication as a delayed post surgery event in order to adapt the care.

关键词： Pseudo-Aneurysm Lumbar Spine Burst Fracture Embolisation

Markers of Heart, Lung and Dorsal Aorta Damage of Mother Rats and Their Neonates Post Therapeutic Treatment with Doxorubicin, Cisplatin and 5-Flurouracil

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Chinese Medicine 2017年第3期8卷 82-99页

作者： Heba A. El-Ghawet Abdelalim A. Gadallah Ahmed A. El-Mansi ali H. Amin hassan I. H. El-Sayyad Zoology Department Faculty of Science Mansoura University Mansoura Egypt Biology Department Faculty of science Jazan University Jazan Saudi Arabia Biology Department Faculty of science King Khaled University Abha Saudi Arabia Deanship of Scientific Research Umm Al-Qura University Mecca Saudi Arabia

Aim: Recently, there is an increased average of developing cancers. Though, the chemotherapeutic-treatment is unfavorable during pregnancy due to its harmful effects on developing fetuses, physicians have two ways to minimize these effects either by termination of the pregnancy or minimizing its side effects. The present work aimed to illustrate the susceptibility of cardiac, lung and dorsal aorta function to the widely applicable drugs doxorubicin and cisplatin as well as 5-flurouracil. Materials and Methods: Mother albino rats were arranged into four-groups (control, doxorubicin, cisplatin and 5-flurouracil-treated groups). Each pregnant rat received intraperitoneal administration of 0.2 mg/kg body weight at 10th and 14th day of gestation and sacrificed at parturition (two doses). At parturition, serum of mother rats used to assess troponin I, heat shock protein 70, 8-hydroxydeoxyguanosine, vascular endothelial growth factor and adhesion molecules (ICAM-1 & VCAM-1). Isoenzyme electrophoresis of alkaline and acid phosphatases, glucose-6-phosphate dehydrogenase and lactic dehydrogenase were estimated in serum, myocardium and dorsal aorta of mother rats. The myocardium and lung were processed for histopathological investigations for both mothers and their offspring. Single strand (comet assay) and double strand DNA damage were carried out in heart and dorsal aorta of mother rats. Results: The present finding revealed that there are detected alterations of myocardial markers and lung amino acid metabolism as well as disruption of myocardial isoenzymes. DNA damage of myocardium and dorsal aorta were observed. Conclusions: The authors concluded that the metabolic activity of heart and lung is highly susceptible to doxorubicin and cisplatin treatment compared to 5-flurouracil and the therapeutic doses must be degraded.

关键词： Anticancer Drugs Heart Lung Dorsal Aorta Isoenzyme Electrophoresis Biochemical Markers Amino Acids DNA Damage

猪支原体肺炎活疫苗(168株)滴鼻免疫保护效果的研究

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河北农业大学学报 2016年第4期39卷 93-97页

作者：杨若松邢宪平冯志新华利忠熊祺琰 hassan Zackaria ali Ishag 邵国青江苏省农业科学院兽医研究所/农业部兽用生物制品工程技术重点实验室/国家兽用生物制品工程技术研究中心南京210014 张家口市动物疫病预防控制中心张家口075000 南京农业大学南京210014 尼亚拉大学兽医学院苏丹00249

本研究通过滴鼻免疫新途径免疫猪支原体肺炎活疫苗168株,与肺内免疫组及对照组进行比较,来确定滴鼻免疫猪支原体肺炎活疫苗(168株)的免疫保护力。将20只猪随机分为肺内免疫组、滴鼻免疫组、健康对照组和攻毒对照组。定期观察和检测各组... 详细信息

本研究通过滴鼻免疫新途径免疫猪支原体肺炎活疫苗168株,与肺内免疫组及对照组进行比较,来确定滴鼻免疫猪支原体肺炎活疫苗(168株)的免疫保护力。将20只猪随机分为肺内免疫组、滴鼻免疫组、健康对照组和攻毒对照组。定期观察和检测各组猪免疫后的临床症状。结果表明:滴鼻免疫组免疫后,猪群体温正常,无免疫引起的局部或全身不良反应,免疫途径安全可行;滴鼻免疫组和肺内免疫组与健康对照组相比,SIgA水平显著升高,差异极显著(P<0.01),但滴鼻免疫组与肺内免疫组相比,差异不显著。流式细胞仪检测显示CD4+数值未发生显著性变化。肺脏剖检评分显示滴鼻免疫组的肺脏的病变水平与攻毒对照组相比呈极显著降低(P<0.01),保护率达到60%,相对低于肺内免疫组100%的保护率。猪支原体肺炎活疫苗(168株)通过滴鼻免疫方式,可以产生较好的免疫保护力。

关键词：猪支原体肺炎活疫苗(168株) 滴鼻免疫 SIgA 肺脏病变

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猪支原体肺炎发病模型的建立

河北农业大学学报 2015年第6期38卷 79-82,87页

作者：杨若松冯志新华利忠熊祺琰 hassan Zackaria ali Ishag 刘茂军邵国青江苏省农业科学院兽医研究所.农业部兽用生物制品工程技术重点实验室.国家兽用生物制品工程技术研究中心南京210014 张家口市动物疫病预防控制中心河北张家口075000 尼亚拉大学兽医学院苏丹00249

本研究旨在选择含有猪肺炎支原体强毒株的猪病肺组织为攻毒材料,建立一种猪支原体肺炎的发病模型。首先,通过荧光定量PCR方法确定猪支原体肺炎冻干病变组织中病原的含量;其次,利用小鼠接种试验,确定该组织毒用做攻毒材料的安全性;再次,... 详细信息

本研究旨在选择含有猪肺炎支原体强毒株的猪病肺组织为攻毒材料,建立一种猪支原体肺炎的发病模型。首先,通过荧光定量PCR方法确定猪支原体肺炎冻干病变组织中病原的含量;其次,利用小鼠接种试验,确定该组织毒用做攻毒材料的安全性;再次,选择猪肺炎支原体阴性大白×二花脸杂交猪,按1：10,1：100,1：1 000,1：10 000稀释后组织强毒经气管内注射途径进行攻毒;最后,攻毒后28 d剖检感染猪,观察肺脏病变情况和临床症状,并通过攻毒剂量比较,确定了猪肺炎支原体感染剂量大于9.50×10^4拷贝时,能够引起猪发病,从而建立猪支原体肺炎人工发病模型,为猪肺炎支原体相关研究提供基础保障。

关键词：猪支原体肺炎动物模型肺脏病变评分

Development of Environment Friendly Paddy Ecosystem for Sustainable Rice Farming through Soil Amendments with Biochar and Alternate Wetting-Drying Irrigations

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American Journal of Climate Change 2021年第4期10卷 581-596页

作者： Muhammad Aslam ali Md. Rajib hassan Zubair Al Islam Sanjit Chandra Barman Badiuzzaman Khan Rehana Khatun Hafsa Jahan Hiya Md. Touhidul Islam Department of Environmental Science Bangladesh Agricultural University Mymensingh Bangladesh Department of Irrigation and Water Management Bangladesh Agricultural University Mymensingh Bangladesh

Climate change may badly affect the availability of water and soil nutrients to rice plant. Research experiments were conducted at the Environmental Science Departmental field, Bangladesh Agricultural University, Mymensingh during July 2017 to June 2019, to find out the suitable combination of biochar with inorganic fertilizers for minimizing seasonal yield scaled CH4 emissions, reducing global warming potentials (GWPs) and sustainable rice farming under feasible irrigation practices. There were ten experimental treatments with different combinations of inorganic NPKS fertilizers and biochar (15 - 30 t/ha) under conventional flooding (CF) and alternate wetting-drying irrigations (AWDI). This study revealed that NPKS fertilization (50% of the recommended doze) with 15 t/ha biochar amendments under AWD irrigation maximized rice yield 6750 kg/ha and 4380 kg/ha in dry boro and wet aman seasons respectively, while the lowest rice yield 1850 kg/ha and 1550 kg/ha were recorded in continuously irrigated control treatment (T1) during the dry and wet seasons respectively. Seasonal cumulative CH4 emission, yield scaled CH4 emission and GWPs were suppressed significantly with biochar amendments 15 - 30 t/ha under both conventional and AWDI irrigation systems during the wet and dry seasons of rice cultivation. Significant interactions were observed among biochar amendments and irrigation practices during the dry boro rice cultivation. Dry seasonal cumulative CH4 emissions were decreased by 14.7%, 18.9% and 24.8% with biochar amendments at 15 t/ha, 20 t/ha and 30 t/ha respectively under conventional irrigation;while cumulative CH4 emissions were reduced by 10.6%, 26% and 41.6% respectively, under AWDI system. Finally, total global warming potentials (GWPs) were decreased by 6% - 15%, 13% - 30% with biochar amendments under conventional and AWDI irrigations respectively, in wet season;while global warming potentials

关键词： CH4 Flux GWPs AWDI Yield Scaled CH4 Emission Dry Boro Rice Rainfed Aman Rice

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基于个性化订单需求的智能制造系统

自动化博览 2018年第S1期35卷 42-44页

作者：孙韬肖馨 Muhammad Arshad Shehzad hassan Mohammed hassan Ahmed Muhammad ali Mehmood 重庆大学电工电子国家级实验教学示范中心重庆400044

目前人工智能制造正逐步覆盖各行各业,可编程控制器(PLC)已被运用于各工业领域的各生产制造过程中。"基于个性化订单需求的智能制造系统"集三菱公司生产的FX5UPLC、人机界面HMI(GOT 2000)、智能传感器、射频识别及相关技术产品于一体,... 详细信息

目前人工智能制造正逐步覆盖各行各业,可编程控制器(PLC)已被运用于各工业领域的各生产制造过程中。"基于个性化订单需求的智能制造系统"集三菱公司生产的FX5UPLC、人机界面HMI(GOT 2000)、智能传感器、射频识别及相关技术产品于一体,模拟了工业生产的实际过程,可满足个性化订单智能制造的要求。该系统可通过HMI预置指令和PLC发出的控制信号对工件进行供料、筛选、识别和标记。

关键词：三菱PLC 人机界面智能传感器射频识别

活体异体结膜缘和羊膜移植治疗化学性眼外伤造成的角膜缘干细胞缺失(英文)

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国际眼科杂志 2008年第6期8卷 1095-1100页

作者： Mehdi Hosseini Tehrani Asoo ali Mahmoudi hassan Hashe-mi Syed Jafar Oskouee Javad Amuzadeh Mohammad Taher Rajabi Masoomeh Taherzadeh Hamideh Shenazandi 伊朗德黑兰大学医学院眼科 Farabi眼科医院眼科研究中心

目的:评价利用活体异体结膜缘和羊膜移植治疗化学性眼外伤造成的角膜缘干细胞缺失的临床效果。方法:从2005-07/2007-12,本研究包括了9名男性化学性眼外伤患者(10眼)。所有患者接受了亲属活体异体结膜缘和羊膜移植,2例眼接受了睑缝术。... 详细信息

目的:评价利用活体异体结膜缘和羊膜移植治疗化学性眼外伤造成的角膜缘干细胞缺失的临床效果。方法:从2005-07/2007-12,本研究包括了9名男性化学性眼外伤患者(10眼)。所有患者接受了亲属活体异体结膜缘和羊膜移植,2例眼接受了睑缝术。用环孢菌素和泼尼松龙进行全身性免疫抑制。结果:在3例眼中观察到完全角膜上皮化(30%),其中1例在术后1.5mo出现免疫排斥,角膜溶解引起穿孔,加大全身性免疫抑制剂量来控制病情。3例眼中植片无法在角膜表面重新形成上皮,被定为原发性失败。其余4眼有部分上皮形成,但上皮细胞无法完全覆盖角膜表面。术前最佳矫正视力从手动到1m处数指,术后最佳矫正视力从光感到20/80。有5眼视力得到改进,不需其他治疗。手术失败的主要原因为干眼症和持续性炎症。结论:对于能控制泪量和眼部炎症的病例,亲属活体异体角膜缘和羊膜移植是治疗化学性眼外伤造成的角膜缘干细胞缺失最佳方法之一。

关键词：眼化学伤活体异体结膜缘移植羊膜移植

Accuracy of urea breath test in Helicobacter pylori infection: Meta-analysis

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World Journal of Gastroenterology 2015年第4期21卷 1305-1314页

作者： Mazen Ferwana Imad Abdulmajeed ali Alhajiahmed Wedad Madani Belal Firwana Rim Hasan Osama Altayar Paul J Limburg Mohammad hassan Murad Bandar Knawy National and Gulf Center for Evidence-Based Health Practice King Saud Bin Abdulaziz University for Health SciencesRiyadh 11426Saudi Arabia Department of Medicine University of Missouri ColumbiaMissouriMO 65211United States Knowledge and Evaluation Research Unit Mayo ClinicRochesterMN 65212United States Knowledge and Evaluation Research Unit Mayo ClinicRochesterMN 55905United States Department of Internal Medicine Allegheny General HospitalPittsburgPA 55905United States Division of Gastroenterology Mayo ClinicRochesterMN 55905United States Division of Preventive Medicine Mayo ClinicRochesterMN 55905United States

AIM: To quantitatively summarize and appraise the available evidence of urea breath test(UBT) use to diagnose Helicobacter pylori(H. pylori) infection in patients with dyspepsia and provide pooled diagnostic accuracy ***: We searched MEDLINE, EMBASE, Cochrane library and other databases for studies addressing the value of UBT in the diagnosis of H. pylori infection. We included cross-sectional studies that evaluated the diagnostic accuracy of UBT in adult patients with dyspeptic symptoms. Risk of bias was assessed using QUADAS(Quality Assessment of Diagnostic Accuracy Studies)-2 tool. Diagnostic accuracy measures were pooled using the random-effects model. Subgroup analysis was conducted by UBT type(13C vs 14C) and by measurement technique(Infrared spectrometry vs Isotope Ratio Mass Spectrometry).RESULTS: Out of 1380 studies identified, only 23 met the eligibility criteria. Fourteen studies(61%) evaluated 13 C UBT and 9 studies(39%) evaluated 14 C UBT. There was significant variation in the type of reference standard tests used across *** sensitivity was 0.96(95%CI: 0.95-0.97) andpooled specificity was 0.93(95%CI: 0.91-0.94). Likelihood ratio for a positive test was 12 and for a negative test was 0.05 with an area under thecurve of 0.985. Meta-analyses were associated with a significant statistical heterogeneity that remained unexplained after subgroup analysis. The included studies had a moderate risk of ***: UBT has high diagnostic accuracy for detecting H. pylori infection in patients with dyspepsia. The reliability of diagnostic meta-analytic estimates however is limited by significant heterogeneity.

关键词： Helicobacter pylori Dyspepsia Breath tests Urea/an

Regulations and ethical codes for clinical cell therapy trials in Iran

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Translational Neuroscience and Clinics 2015年第2期1卷 110-113页

作者： Hooshang Saberi Nazi Derakhshanrad Babak Arjmand Jafar Ai Masoud Soleymani Amir ali Hamidieh Mohammad Taghi Joghataei Zahid Hussain Khan Seyed hassan Emami Razavi Department of Neurosurgery Imam Khomeini HospitalTehran University of Medical Sciences Brain and Spinal cord Injuries Repair Research Center Tehran University of Medical Sciences cG MP‐Compliant Stem Cell Facility Brain and Spinal Cord Injury Research Center Tehran University of Medical Sciences Department of Hematology Tarbiat Modarres University Department of Hematology-Oncology Shariati Hospital Tehran University of Medical Sciences Department of Anatomy Cellular and Molecular Research Center Iran University of Medical Sciences Department of Neurosurgery Imam Khomeini HospitalTehran University of Medical Sciences

Objective: The local regulations for conducting experimental and clinical cell therapy studies are dependent on the national and cultural approach to the issue, and may have many common aspects as well as differences with the regulations in other *** study reflects the latest national aspects of cell therapy in Iran and relevant regulations. Methods: The following topics are discussed in the article including sources of cell harvest, regulations for cell disposal, stem cell manufacturing, and economic aspects of stem cell, based on current practice in Iran. Results: All cell therapy trials in Iran are required to strictly abide with the ethical codes, national and local regulations, and safety requirements, as well as considering human rights and respect. Adherence to these standards has facilitated the conduct of human cell therapy trials for research, academic advancement, and therapy. Conclusions: The cell therapy trials based on the aforementioned regulations may be assumed to be ethical and they are candidates for clinical translations based on safety and efficacy issues.

关键词： stem cell research ethical codes animal models cell therapy embryonic