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Coinfection of SARS-CoV-2 Omicron variant and other respiratory pathogens in children

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World Journal of Pediatrics 2024年第1期20卷 92-96页

作者： Wei Li bing-Han Wang bao-Hai Chen Yi Sun Lin Li Wen-Qing Xiang Ahmed Faisal ali Lin-Xuan Su Hai-Yan Mao Hong-Qiang Shen Qiang Shu Department of Clinical Laboratory Children's HospitalNational Clinical Research Center for Child HealthZhejiang University School of MedicineHangzhouChina School of Public Health Zhejiang University School of MedicineHangzhouChina Department of Information Center Children's HospitalZhejiang University School of MedicineHangzhouChina Zhejiang Provincial Center for Disease Control and Prevention HangzhouChina Department of Thoracic&Cardiovascular Surgery Children's HospitalNational Clinical Research Center for Child HealthZhejiang University School of MedicineHangzhouChina

Since the outbreak of coronavirus disease 2019(COVID-19),the entire world has been affected by the epidemic[1,2].On November 9,2021,a variant of the novel coronavirus b.1.1.529 was detected for the first time from case samples in South *** Omicron strain spread and mutated significantly *** variant has the characteristics of escape immunity,which can induce relatively extreme disease and reduce the neutralization of antibodies in vaccinators,and is more likely to be reinfected[3,4].The clinical presentation of severe acute respiratory syndrome coronavirus 2(SARSCoV-2)in children has mild symptoms and a lower risk of hospitalization and death.

关键词： respiratory immunity acute

Evaluation of immunogenicity and reactogenicity of recombinant DNA hepatitis b vaccine produced in India

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World Journal of Gastroenterology 2005年第45期11卷 7165-7168页

作者： Zahid Hussain syed S ali syed A Husain Mohammad Raish Deepika R Sharma Premashis Kar PCR Hepatitis Laboratory Panacea biotec Ltd Mohammad Raish

AIM：（1） To gain information on immune responses to an accelerated schedule of 0, 1, and 2 mo in paramedical staff and bDS students who are at an increased risk of getting hepatitis b infection and come under high risk groups. （2） To assess the efficacy and safety of En/vac- Hb in different age groups, using genetically modified yeast strain Pichia pastoris, a new recombinant hepatitis b accine developed and manufactured in India. METHODS： A prospective, comparative, and single blinded trial of rapid （0, 1, and 2 mo） hepatitis b immunization schedulewas reported. A total of three hundred and seven （212 females and 95 males） healthy volunteers divided into three age groups （18-29, 30-39, and 40-49） were enrolled after screening for markers of hepatitis b. All the volunteers received 20 mg of the vaccine intramuscularly at 0, 1, and 2 mo. RESULTS： Geometric mean titers were calculated pre and post vaccination. before immunization the GMT was 0.0124 mIU/mL. One month after the administration of the third dose of recombinant vaccine 296/307 （96.5%） subjects achieved seroprotective levels of anti-Hbs. The geometric mean anti-Hbs titers achieved after one month of the third dose was 2 560.0 mIU/mL. The geometric mean anti-Hbs titer of males was 2 029.0 mIU/mL, while that of the females was 2 759.0 mIU/mL. In the age group of 18-29 years, anti-Hbs titer was 3 025.0 mIU/ mL, while that in the age group of 30-39 years was 2 096.0 mlU/mL. In third age group of 40-49 years, anti- Hbs titer was 1 592.0 mIU/mL. Hyper-responses （anti-Hbs≥100 mIU/mL） were shown in 88.0% （271/307） of subjects. Eleven （3.5%） subjects responded poorly to the vaccine in the age group of 40-49 years. There was only mild pain at the site of injection otherwise there were no other adverse drug reactions （ADRs）. CONCLUSION： This vaccine （Enivac-Hb） is safe and efficacious, providing significant protection after the third dose and rapid hepatitis b immunization schedule of 0, 1, and 2 mo can be recommended

关键词： Enivac-Hb Pichia pastoris Anti-Hbsantibody Hepatitis b vaccine

A novel (G'/G)-expansion method and its application to the boussinesq equation

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Chinese Physics b 2014年第2期23卷 34-43页

作者： Md.Nur Alam Md.ali Akbar syed Tauseef Mohyud-Din Department of Mathematics Pabna University of Science and Technology Department of Applied Mathematics University of Rajshahi Department of Mathematics HITEC UniversityTaxila Cantt

In this article, a novel （G＇/G）-expansion method is proposed to search for the traveling wave solutions of nonlinear evolution equations. We construct abundant traveling wave solutions involving parameters to the boussinesq equation by means of the suggested method. The performance of the method is reliable and useful, and gives more general exact solutions than the existing methods. The new （G＇/G）-expansion method provides not only more general forms of solutions but also cuspon, peakon, soliton, and periodic waves.

关键词： (G'/G)-expansion method boussinesq equation solitary wave solutions auxiliary nonlinear ordinary differential equation

A novel antimicrobial flavonoidic glycoside from the leaves of Alstonia macrophylla Wall ex ***(Apocynaceae)

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Chinese Chemical Letters 2010年第5期21卷 593-595页

作者： Mehtab Parveen Zakia Khanam Akhtar ali syed Mohmud Ahmad Department of Chemistry Aligarh Muslim UniversityAligarhU.P.202002India

A new flavonoidic glycoside,tricin-4’-O-β-L-arabinoside(1) was isolated from the leaves of Alstonia macrophylla along with two known flavonoids,vitexin and myricetin-3′-*** structures were established by chemical and spectral *** known compounds were reported for the first time from this *** compound 1 was tested for antifungal and antibacterial activities.

关键词： Alstonia macrophylla Vitexin Myricetin-3’-rhamnoside-3-O-galactoside Tricin-4′-O-β-L-arabinoside Antibacterial Antifungal activity

A decline in snow cover area of Passu and Ghulkin valleys between 1995 and 2022

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Journal of Mountain Science 2023年第12期20卷 3542-3551页

作者： Imran HUSSAIN Mumtaz ali Sher MUHAMMAD Wajid HASSAN Salar ali Zakir HUSSAIN syed Hammad ali Shaukat ali Muhammad Younis KHAN Department of Environmental Sciences University of BaltistanSkardu 16100Pakistan Micromaps IT and GIS Consultancy LLC 26135UAE International Centers for Integrated Mountain Development(ICIMOD) G.P.O.Box 3226KathmanduNepal Institute of Mountain Hazards and Environment Chinese Academy of SciencesChengdu 610041China University of Chinese Academy of Sciences Beijing 100049China Glacier Monitoring Research Centre(GMRC) Water and Power Development Authority(WAPDA)Lahore 54000Pakistan SickKids Centre for Global Child Health The Hospital for Sick ChildrenTorontoOntario M5G 2L3Canada Global Change Impact Studies Center(GCISC) Islamabad 44000Pakistan Departments of Earth Sciences College of ScienceSultan Qaboos UniversityMuscat 123Oman National Centers of Excellence in Geology(NCEG) University of PeshawarPeshawar 25130Pakistan

The global cryosphere is experiencing accelerated melting due to climate ***,the Karakoram anomaly is under discussion with a debate about the possibility that the anomaly may have recently *** study aims to evaluate the up-to-date changes in snow cover in the western Karakoram *** observed the snow cover changes in Passu and Ghulkin valleys in the Hunza River basin(HRb)of the Karakoram through multitemporal Landsat satellite data between 1995 and *** found a significant reduction in snow cover in these valleys,with an average reduction rate of 0.42 km~2/yr,resulting in a total reduction of~11.46 km~2 between 1995 and *** reduction in snow cover is consistent with the mass loss of glaciers in the Karakoram region in recent *** decline in snow cover in these valleys is also consistent with the meteorological *** temperature in summer(June)has significantly increased whereas the precipitation in the accumulation season(March)has *** rapid changes suggest that it is crucially important to monitor the snow cover on a regular basis to support downstream management of snowmelt *** addition,there is a need of planning for mitigation and adaptation strategies for snow-related hazards.

关键词： Cryosphere Snow covers area Climate change Karakoram

CONTROL OF VEHICLE PLATOONS FOR HIGHWAY SAFETY AND EFFICIENT UTILITY:CONSENSUS WITH COMMUNICATIONS AND VEHICLE DYNAMICS

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Journal of Systems Science & Complexity 2014年第4期27卷 605-631页

作者： WANG Le Yi syed ali YIN Gang George PANDYA Abhilash ZHANG Hongwei Department of Electrical and Computer Engineering Wayne State University Department of Mathematics Wayne State University Department of Computer Science Wayne State University

Platoon formation of highway vehicles is a critical foundation for autonomous or semiautonomous vehicle control for enhanced safety,improved highway utility,increased fuel economy,and reduced emission toward intelligent transportation *** control encounters great challenges from vehicle control,communications,team coordination,and *** paper introduces a new method for coordinated control of platoons by using integrated network consensus decisions and vehicle *** achieve suitable coordination of the team vehicles based on terrain and environmental conditions,the emerging technology of network consensus control is modified to a weighted and constrained consensus-seeking *** are introduced and their convergence properties are *** methodology employs neighborhood information through on-board sensors and V2 V or V2 I communications,but achieves global coordination of the entire *** ability of the methods in terms of robustness,disturbance rejection,noise attenuation,and cyber-physical interaction is analyzed and demonstrated with simulated case studies.

关键词： Collision avoidance communications consensus control networked systems platoon con-trol safety vehicle dynamics.

Machine learning empowered COVID-19 patient monitoring using non-contact sensing:An extensive review

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Journal of Pharmaceutical Analysis 2022年第2期12卷 193-204页

作者： Umer Saeed syed Yaseen Shah Jawad Ahmad Muhammad ali Imran Qammer H.Abbasi syed Aziz Shah Research Centre for Intelligent Healthcare Coventry UniversityCoventryCV15FBUK School of Computing Engineering and Built EnvironmentGlasgow Caledonian UniversityGlasgowG40BAUK School of Computing Edinburgh Napier UniversityEdinburghEH114BNUK James Watt School of Engineering University of GlasgowGlasgowG128QQUK

The severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),which caused the coronavirus disease 2019(COVID-19)pandemic,has affected more than 400 million people *** the recent rise of new Delta and Omicron variants,the efficacy of the vaccines has become an important *** goal of various studies has been to limit the spread of the virus by utilizing wireless sensing technologies to prevent human-to-human interactions,particularly for healthcare *** this paper,we discuss the current literature on invasive/contact and non-invasive/noncontact technologies(including Wi-Fi,radar,and software-defined radio)that have been effectively used to detect,diagnose,and monitor human activities and COVID-19 related symptoms,such as irregular *** addition,we focused on cutting-edge machine learning algorithms(such as generative adversarial networks,random forest,multilayer perceptron,support vector machine,extremely randomized trees,and k-nearest neighbors)and their essential role in intelligent healthcare ***,this study highlights the limitations related to non-invasive techniques and prospective research directions.

关键词： Artificial intelligence Non-invasive healthcare Machine learning Non-contact sensing COVID-19

National guidelines for the diagnosis and treatment of hilar cholangiocarcinoma

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World Journal of Gastroenterology 2024年第9期30卷 1018-1042页

作者： Faisal Saud Dar Zaigham Abbas Irfan Ahmed Muhammad Atique Usman Iqbal Aujla Muhammad Azeemuddin Zeba Aziz Abu bakar Hafeez bhatti Tariq ali bangash Amna Subhan butt Osama Tariq butt Abdul Wahab Dogar Javed Iqbal Farooqi Faisal Hanif Jahanzaib Haider Siraj Haider syed Mujahid Hassan Adnan Abdul Jabbar Aman Nawaz Khan Muhammad Shoaib Khan Muhammad Yasir Khan Amer Latif Nasir Hassan Luck Ahmad Karim Malik Kamran Rashid Sohail Rashid Mohammad Salih Abdullah Saeed Amjad Salamat Ghias-un-Nabi Tayyab Aasim Yusuf Haseeb Haider Zia Ammara Naveed Department of Hepatopancreatic biliary Surgery&Liver Transplant Pakistan Kidney and Liver Institute&Research CentreLahore 54000Pakistan Department of Hepatogastroenterology and Liver Transplantation Dr.Ziauddin University HospitalKarachi 75600SindhPakistan University of Aberdeen Aberdeen B243FXUnited Kingdom Department of Pathology Pakistan Kidney and Liver Institute&Research CentreLahore 54000Pakistan Department of Gastroenterology&Hepatology Pakistan Kidney and Liver Institute&Research CentreLahore 54000Pakistan Department of Radiology Aga Khan UniversityKarachi 74800Pakistan Department of Oncology Hameed Latif HospitalLahore 54000Pakistan Division of Hepatopancreatic biliary Surgery&Liver Transplantation Shifa International HospitalIslamabad 44000Pakistan Department of Hepatopancreatic biliary Surgery&Liver Transplant Shaikh Zayed Hospital and Post Graduate Medical InstituteLahore 54000Pakistan Department of Medicine Aga Khan University HospitalKarachi 74800Pakistan Department of Liver Transplant Pir Abdul Qadir Shah Jeelani Institute of Medical SciencesGambat 66020Pakistan Department of Medicine&Gastroenterology Lifecare Hospital and Research CentrePeshawar 25000Khyber PakhtunkhwaPakistan Department of Hepatopancreatobiliary&Liver Transplant Bahria International HospitalLahore 54000Pakistan Department of Surgery Hepatopancreatobiliary&Liver TransplantDow University of Health SciencesKarachi 74800Pakistan Department of Gastroenterology Hepatology&NutritionPir Abdul Qadir Shah Jeelani Institute of Medical SciencesGambat 66020Pakistan Department of Oncology Dr.Ziauddin HospitalKarachi 74800Pakistan Department of Radiology Rehman Medical InstitutePeshawar 25000Pakistan Army Liver Transplant Unit Pak Emirates Military HospitalRawalpindi 46000Pakistan Department of Gastroenterology Sindh Institute of Urology and TransplantationKarachi 75500Pakistan Rashid Nursing Home and Cancer Clinic Rashid Nursing Home and Cancer ClinicRawalpindi 46000Pakistan Department of Gastroentero

A consensus meeting of national experts from all major national hepatobiliary centres in the country was held on May 26,2023,at the Pakistan Kidney and Liver Institute&Research Centre(PKLI&RC)after initial consultations with the *** Pakistan Society for the Study of Liver Diseases(PSSLD)and PKLI&RC jointly organised this *** effort was based on a comprehensive literature review to establish national practice guidelines for hilar cholangiocarcinoma(hCCA).The consensus was that hCCA is a complex disease and requires a multidisciplinary team approach to best manage these *** coordinated effort can minimise delays and give patients a chance for curative treatment and effective *** diagnostic and staging workup includes high-quality computed tomography,magnetic resonance imaging,and magnetic resonance *** cytology or biopsy utilizing endoscopic retrograde cholangiopancreatography is a mainstay for ***,histopathologic confirmation is not always required before *** ultrasound with fine needle aspiration of regional lymph nodes and positron emission tomography scan are valuable adjuncts for *** only curative treatment is the surgical resection of the biliary tree based on the bismuth-Corlette *** patients with unresectable hCCA can be considered for liver *** chemotherapy should be offered to patients with a high risk of *** use of preoperative biliary drainage and the need for portal vein embolisation should be based on local multidisciplinary *** with acute cholangitis can be drained with endoscopic or percutaneous biliary *** chemotherapy with cisplatin and gemcitabine has shown improved survival in patients with irresectable and recurrent hCCA.

关键词： Hilar cholangiocarcinoma bismuth-Corlette classification Memorial Sloan Kettering Cancer Centre Staging Preoperative biliary drainage Portal vein embolisation Surgical resection Hepatectomy

SYNCHRONIZATION OF MASTER-SLAVE MARKOVIAN SWITCHING COMPLEX DYNAMICAL NETWORKS WITH TIME-VARYING DELAYS IN NONLINEAR FUNCTION VIA SLIDING MODE CONTROL

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Acta Mathematica Scientia 2017年第2期37卷 368-384页

作者： M.syed ali J.YOGAMbIGAI 曹进德 Department of Mathematics Thiruvalluvar UniversityVellore 632115Tamil NaduIndia Department of Mathematics Southeast UniversityNanjing 210096China Department of Mathematics Faculty of ScienceKing Abdulaziz UniversityJeddah 21589Saudi Arabia

In this article, a synchronization problem for master-slave Markovian switching complex dynamical networks with time-varying delays in nonlinear function via sliding mode control is investigated. On the basis of the appropriate Lyapunov-Krasovskii functional, introducing some free weighting matrices, new synchronization criteria are derived in terms of linear matrix inequalities （LMIs）. Then, an integral sliding surface is designed to guarantee synchronization of master-slave Markovian switching complex dynamical networks, and the suitable controller is synthesized to ensure that the trajectory of the closed-loop error system can be driven onto the prescribed sliding mode surface. by using Dynkin＇s formula, we established the stochastic stablity of master-slave system. Finally, numerical example is provided to demonstrate the effectiveness of the obtained theoretical results.

关键词： Markovian switching complex dynamical networks Lyapunov-Krasovskii method sliding mode control Linear Matrix Inequality