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Long COVID in children and adolescents

World Journal of Pediatrics 2021年第5期17卷 495-499页

作者： ali a.asadi-pooya Hamid Nemati Mina Shahisavandi ali Akbari Amir Emami Mehrzad Lotfi Mahtab Rostamihosseinkhani Zohreh Barzegar Maryam Kabiri Zahra Zeraatpisheh Mohsen Farjoud-Kouhanjani Anahita Jafari Fateme Sasannia Shayan Ashrafi Masoume Nazeri Sara Nasiri Epilepsy Research Center Shiraz University of Medical SciencesShirazIran Department of Ncurology Jefferson Comprehensive Epilepsy CenterThomas Jefferson UniversityPhiladelphiaPAUSA Department of Anesthesiology School of Medicine.Shiraz University of Medical SciencesShirazIran Burn&Wound Healing Research Center Shiraz University of Medical SciencesShirazIran Medical Imaging Research Center Shiraz University of Medical SciencesShirazIran

Background To identify the prevalence and also the full spectrum of symptoms/complaints of children and adolescents who are suffering from long ***,we investigated the risk factors of long COVID in children and *** All consecutive children and adolescents who were referred to the hospitals anywhere in Fars province,Iran,from 19 February 2020 until 20 November 2020 were *** patients had a confirmed diagnosis of *** *** call to patients/parents,at least 3 months after their discharge from the hospital,we obtained their current status and information if their parents agreed to *** In total,58 children and adolescents fulillel the inclusion ***-six(448%)children/adolescents reported symptoms/complaints of long *** symptoms included fatigue in 12(21%),shortness of breath in 7(12%),exer-cise intolerance in 7(12%),weakness in 6(10%),and walking intolerance in 5(9%)*** age,muscle pain on admission,and intensive care unit admission were significantly associated with long *** Long COVID is a frequent condition in children and *** scientific community should inves-tigate and explore the pathophysiology of long COVID to ensure that these patients receive appropriate treatments for their condition.

关键词： Adolescents Children COVID-19 Coronavirus Chronic Pediatrics

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Role of molecular imaging in prognosis,diagnosis,and treatment of gastrointestinal cancers:An update on new therapeutic methods

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World Journal of Methodology 2024年第4期14卷 43-60页

作者： Mobina Fathi Hayder Jasim Taher Sabah Jassim Al-Rubiae Shirin Yaghoobpoor Ashkan Bahrami Reza Eshraghi Hossein Sadri Mahsa.asadi Anar ali Gholamrezanezhad Student Research Committee School of MedicineShahid Beheshti University of Medical SciencesTehran ***Iran Department of Radiology Hilla University CollegeBabylon 00964Iraq Faculty of Medicine Kashan University of Medical SciencesKashan ***Iran Department of Radiology Keck School of MedicineUniversity of Southern CaliforniaLos AngelesCA 90033United States

One of the leading causes of cancer-related death is gastrointestinal cancer,which has a significant morbidity and mortality *** preoperative risk assessment is essential for directing patient care,its biological behavior cannot be accurately predicted by conventional imaging *** pathophysiological information in anatomical imaging that cannot be visually identified can now be converted into high-dimensional quantitative image features thanks to the developing discipline of molecular *** order to enable molecular tissue profile in vivo,molecular imaging has most recently been utilized to phenotype the expression of single receptors and targets of biological *** is expected that molecular imaging will become increasingly important in the near future,driven by the expanding range of biological therapies for *** this live molecular fingerprinting,molecular imaging can be utilized to drive expression-tailored customized *** technical aspects of molecular imaging are first briefly discussed in this review,followed by an examination of the most recent research on the diagnosis,prognosis,and potential future clinical methods of molecular imaging for GI tract malignancies.

关键词： Molecular imaging Personalized medicine Gastrointestinal cancers Positron emission tomography-computed tomography

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Geochemical Investigation of the Cretaceous Crude Oil Reservoirs and Source Rock Samples in One of the Abadan Plain Oilfields, SW Iran

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Acta Geologica Sinica(English Edition) 2022年第2期96卷 546-558页

作者： Elham asadi MEHMANDOSTI Mahnaz AMIRHOSEYNI Seyed ali MOALLEMI Azizollah HABIBI Department of Geology Faculty of Earth SciencesKharazmi UniversityTehranIran Research Institute of Petroleum Industry TehranIran Faculty of Chemistry Sciences Kharazmi UniversityTehranIran

Crude oil and source rock samples from one of the main oilfields of the Abadan Plain, Zagros, Iran were analyzed geochemically. Rock-Eval pyrolysis was conducted on Kazhdumi(Upper Cretaceous) and Gadvan(Lower Cretaceous) formations, which are the probable source rocks for the oil in the region. The results indicated that the Kazhdumi Formation can be classified as a fair-to-excellent source rock, while the Gadvan Formation can be identified as having poor-to-good source rock in the basin. Based on the cross-plots of HI versus OI and S2 versus TOC, types Ⅱ and Ⅲ kerogen were identified from studied source samples in the area. Determination of the main fraction percentages of the Sarvak and Fahliyan crude oils represented that the oils from the Sarvak reservoir are paraffinic-naphthenic and aromaticintermediate, whilst that from the Fahliyan reservoir is paraffinic and paraffinic-naphthenic. Biomarker ratios of the saturated fractions of oil from both reservoirs indicate that the source rocks formed in reducing marine environments with carbonate-shale lithology. Furthermore, biomarker data helped to distinguish the degree of biodegradation in the studied oils. According to geochemical analysis, oil samples from the Fahliyan reservoir were generated at a higher thermal maturity than the Sarvak reservoir samples.

关键词： biomarker crude oil source rock Cretaceous reservoir Zagros Iran

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Association of mitochondrial dysfunction and,lipid metabolism with type 2diabetes mellitus:A review of literature

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Frontiers in Biology 2018年第6期13卷 406-417页

作者： Karimeh Haghani Pouyan asadi Gholamreza Taheripak ali Noori-Zadeh Shahram Darabi Salar Bakhtiyari Department of Clinical Biochemistry Faculty of MedicineIlam University of Medical SciencesIlamIran Medical Cellular &Molecular Research Center Golestan University of Medical SciencesGorgan1ran Department of Clinical Biochemistry School of Medicine1ran University of Medical SciencesTehran1ran Department of Clinical Biochemistry Faculty of Paramedicine1lain University of Medical Sciencesllam1ran Cellular and Molecular Research Center Qazvin University of Medical ScienceQazvin1ran

Diabetes mellitus (DM) is one of the most prevalent chronic diseases, and its prevalence continues to increase globally. The impact of mitochondrial dysfunction and lipid metabolism on diabetes mellitus and insulin resistance (IR) has been implicated in several previous reports; however, the results of studies are confusing despite four decades of study. This review has evaluated updated understanding of the role of mitochondrial dysfunction and lipid metabolism on type 2 diabetes, and found that mitochondrial dysfunction and lipid metabolism disorder induce the dysregulation of liver and pancreatic beta cells, insulin resistance, and type 2 diabetes. Mitochondrial dysfunction and lipid metabolism induce metabolic dysregulation and finally increasing the possibility of diabetes.

关键词： Insulin resistance Type 2 diabetes Mitochondrial dysfunction Lipid metabolism

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LOCAL GAUSSIAN-COLLOCATION SCHEME TO APPROXIMATE THE SOLUTION OF NONLINEAR FRACTIONAL DIFFERENTIAL EQUATIONS USING VOLTERRA INTEGRAL EQUATIONS

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Journal of Computational Mathematics 2021年第2期39卷 261-282页

作者： Pouria Assari Fatemeh asadi-Mehregan Mehdi Dehghan Department of Mathematics Faculty of SciencesBu-Ali Sina UniversityHamedan 65178Iran Department of Applied Mathematics Faculty of Mathematics and Computer SciencesAmirkabir University of TechnologyNo.424Hafez Ave.Tehran 15914Iran

This work describes an accurate and effective method for numerically solving a class of nonlinear fractional differential *** start the method,we equivalently convert these types of differential equations to nonlinear fractional Volterra integral equations of the second kind by integrating from both sides of ***,the solution of the mentioned Volterra integral equations can be estimated using the collocation method based on locally supported Gaussian *** local Gaussian-collocation scheme estimates the unknown function utilizing a small set of data instead of all points in the solution domain,so the proposed method uses much less computer memory and volume computing in comparison with global *** apply the composite non-uniform Gauss-Legendre quadrature formula to estimate singular-fractional integrals in the *** of the fact that the proposed scheme requires no cell structures on the domain,it is a meshless ***,we obtain the error analysis of the proposed method and demon-strate that the convergence rate of the approach is arbitrarily *** examples clearly show the reliability and efficiency of the new technique and confirm the theoretical error estimates.

关键词： Nonlinear fractional differential equation Volterra integral equation Gaussian-collocation method Meshless method Error analysis

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Medicinal plants with hepatoprotective activity in Iranian folk medicine

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Asian Pacific Journal of Tropical Biomedicine 2015年第2期5卷 146-157页

作者： Majid asadi-Samani Najme Kafash-Farkhad Nafiseh Azimi ali Fasihi Ebrahim alinia-Ahandani Mahmoud Rafieian-Kopaei Medical Plants Research Center Shahrekord University of Medical Sciences Department of Biology Faculty of ScienceUrmia University Department of Biology Science and Research BranchIslamic Azad University Department of Genetics Faculty of Biology ScienceTarbit Modares University

There are a number of medicinal combinations in the Iranian traditional medicine which are commonly used as tonic for *** this review,we have introduced some medicinal plants that are used mainly for the treatment of liver disorders in Iranian folk medicine,with focus on their hepatoprotective effects particularly against CCI_4 *** this study,online databases including Web of ***,and Science Direct were searched for papers published from January 1970 to December *** terms consisted of medicinal plants,traditional medicine,folk medicine,***,liver,therapeutic uses,compounds,***_***-inflammatory,and antihepatotoxic,hepatitis,alone or in *** hirtifolium Boiss..Apium graveolens L..Cynara *** vulgaris L..,Calendula officinalis,Nigella sativa L..Taraxacum *** *** ferulacea L..Allium sativum,Marribium vulgare,Ammi majus L..Citrullus lanatus *** eupatoria *** Primus armeniaca *** some of the medicinal plants that have been used for the treatment of liver disorders in Iranian folk *** of several leads obtained from plants containing potential hepatoprotective agents,silymarin,P-sitosterol,betalain,***,and glycyrrhizin have been demonstrated to have potent hepatoprotective *** encouraging data on possibility of new discoveries in the near future,the evidence on treating viral hepatitis or other chronic liver diseases by herbal medications is not adequate.

关键词： Medicinal plants Iran Compounds Liver Therapeutic uses CCl_4

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悬浮固化液相微萃取-高效液相色谱法测定人血浆和尿样中的卡巴咪嗪（英文）

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色谱 2015年第6期33卷 634-641页

作者： Mohammad asadi ali Mohammad HAJI SHABANI Shayessteh DADFARNIA Bijan ABBASI Department of Chemistry Faculty of ScienceYazd University Khorassan Research Institute for Food Science and Technology

Solidified floating organic drop microextraction(SFODME)in combination with high performance liquid chromatography was used for separation/preconcentration and determination of carbamazepine(CBZ)in human plasma and urine *** that affect the extraction efficiency such as the type and volume of extraction solvent,ionic strength,sodium hydroxide concentration,stirring rate,sample volume and extraction time,were investigated and *** the optimum conditions(extraction solvent,40μL of 1-undecanol;sodium hydroxide concentration,1 mol/L;temperature,50℃;stirring speed,400 r/min;sample volume,8 mL;sodium chloride concentration,3%(w/v)and extraction time,60 min)the calibration curve was found to be linear in the mass concentration range of 0.4-700.0μg/*** limit of detection(LOD)was 0.1μg/L and the relative standard deviation(RSD)for six replicate extraction and determination of carbamazepine at 100μg/L level was found to be 4.1%.The method was successfully applied to the determination of CBZ in human plasma and urine samples.

关键词： solidified floating organic drop microextraction(SFODME) high performance liquid chromatogra-phy(HPLC) carbamazepine(CBZ) plasma urine preconcentration

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Comparison of Sensory Processing and Semantic Differentiation in Peoples with Schizophrenia, Multiple Sclerosis and Alzheimer’s Disease

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International Journal of Clinical Medicine 2017年第4期8卷 257-264页

作者： Jahan Sadat asadi Bijaeyeh Hosein Ghamari Givi ali Sheykholeslami Educated of MA Rehabilitation Counseling Faculty of Education and Psychology University of Mohaghegh Ardabili Ardabil Iran Professor Faculty of Education and Psychology University of Mohaghegh Ardabili Ardabil Iran Assistant Professor Faculty of Education and Psychology University of Mohaghegh Ardabili Ardabil Iran

Aim: The purpose of this study was comparison of sensory processing and semantic differentiation in patients with schizophrenia, multiple sclerosis (MS) and Alzheimer’s disease. Method: Our research method was causal-comparative. Statistical population were patients with schizophrenia and patients with multiple sclerosis and Alzheimer’s disease that are kept by formal caregivers in welfare centers in Guilan or by informal caregivers in families in Rasht city of Guilan province in Iran. 45 persons with MS, Alzheimer’s disease and schizophrenia (in each group 15 persons) were randomly selected by accessible sampling method in 2014. Then, subjects were asked to response to sensory profile questionnaires to measure of sensory processing and ozgood semantic differentiation questionnaires to measure of semantic differentiation, then raw data were analyzed by multiple analyses of variance with using of spss16 software. Results: P value less than 0.05, namely p 0.05), had the maximum mean in three groups. Discussion and Conclusion: Because sensory processing and semantic differentiation aren’t in a desirable condition in patients with schizophrenia, so it is necessary that the people who are at high risk of developing the disease or the initial stages of the disease, must be acted to improve their sensory processing and semantic differentiation.

关键词： Schizophrenia Multiple Sclerosis Alzheimer Sensory Processing Semantic Differentiation

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Calculation of dpa rate in graphite box of Tehran Research Reactor(TRR)

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Nuclear Science and Techniques 2019年第6期30卷 44-56页

作者： Mohamad Amin Amirkhani Mohsen asadi Asadabad Mostafa Hassanzadeh Seyed Mohammad Mirvakili ali Mohammadi Reactor and Nuclear Safety Research School Nuclear Science and Technology Research Institute Tehran Iran Department of Physics Arak University Arak Iran

Radiation damage is an important factor that must be considered while designing nuclear facilities and nuclear materials. In this study, radiation damage is investigated in graphite, which is used as a neutron reflector in the Tehran Research Reactor (TRR) core. Radiation damage is shown by displacement per atom (dpa) unit. A cross section of the material was created by using the SPECOMP code. The concentration of impurities present in the non-irradiated graphite was measured by using the ICP-AES method. In the present study the MCNPX code had identified the most sensitive location for radiation damage inside the reactor core. Subsequently, the radiation damage (spectral-averaged dpa values) in the aforementioned location was calculated by using the SPECTER, SRIM Monte Carlo codes, and Norgett, Robinson and Torrens (NRT) model. The results of “Ion Distribution and Quick Calculation of Damage”(QD) method groups had a minor difference with the results of the SPECTER code and NRT model. The maximum radiation damage rate calculated for the graphite present in the TRR core was 1.567 9 10^-8 dpa/s. Finally, hydrogen retention was calculated as a function of the irradiation time.

关键词： Radiation damage Graphite SPECTER SRIM MCNPX Tehran Research Reactor

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Identification of Fungal Communities in Producing Compost by Windrow Method

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Journal of Environmental Protection 2012年第1期3卷 61-67页

作者： Rouhullah Dehghani Mohammad ali asadi Esmail Charkhloo Gholamreza Mostafaie Mohmoud Saffari Gholam Abbas Mousavi Mohammad Pourbabaei 不详

Considering the importance of fungal genera in producing compost from piling organic matter or biodegradable waste, this study aimed to identify the fungal species and their negative effect on human health during the compost production by windrow method. In this descriptive study, 99 compost samples were collected from the composting research site at Kashan University of medical sciences within 63 days from Oct 3 to Dec 4, 2010. Sixty-six samples were cultured to determine the fungal species and 33 samples were transferred to the laboratory to determine the physical and chemical parameters. Twenty-five fungal species were identified during the compost process including 15 saprophytes, 8 dermatophites, 1 opportunistic and 1 yeast fungi. Identified fungal species during the compost process according to their frequencies were Aspergillus spp )34.45%), Microsporium spp (18.89%), Trichophyton spp (8.89%), Yeast sp (6.67%), Mucor sp (5.56%), Penicillium sp )4.45%), Rhizopus sp (4.45%), Fusarium sp (3.34%), Cladosporium sp )3.34%), Curvularia sp (3.34%) and also other fungal species (6.62%), respectively. Considering the presence of various pathogenic fungi during the composting process, the employees of the compost factory should use individual protective devices and also due to the presence of 11 fungal species in the mature compost and their pathogenic effect, preventive measures should be taken by persons involved in the production of compost especially farmers, in order to prevent successive inhalation of spores.

关键词： Compost Windrow Method Fungal Species

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