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Attenuation of dextran sodium sulphate induced colitis in matrix metalloproteinase-9 deficient mice

World Journal of Gastroenterology 2006年第40期12卷 6464-6472页

作者： alfredo santana Carlos Medina Maria Cristina Paz-Cabrera Federico Díaz-Gonzalez Esther Farré Antonio Salas Marek W Radomski Enrique Quintero Gastroenterology Department and Research Unit Hospital Universitario de Canarias Tenerife Spain Reumathology Department Hospital Universitario de Canrias Tenerife Spain Pathology Department Hospital Mutua de Terrassa Barcelona Spain Institute of Molecular Medicine University of Texas Houston-Texas United States

AIM: To study whether matrix metalloproteinase-9 (MMP-9) is a key factor in epithelial damage in the dextran sodium sulphate (DSS) model of colitis in ***: MMP-9-deficient and wild-type (wt) mice were given 5% DSS in drinking water for 5 d followed by recovery up to 7 d. On d 5 and 12 after induction of colitis, gelatinases, MMP-2 and MMP-9, were measured in homogenates of colonic tissue by zymography and Western blot, whereas tissue inhibitor of metalloproteinases (TIMPs) were measured by reverse zymography. The gelatinolytic activity was also determined in supernatants of polymorphonuclear leukocytes (PMN) isolated from mice blood. Moreover, intestinal epithelial cells were stimulated with TNF-α to study whether these cells were able to produce MMPs. Finally, colonic mucosal lesions were measured by microscopic examination. RESULTS: On d 5 of colitis, the activity of MMP-9 was increased in homogenates of colonic tissues (0.24 ± 0.1 vs 21.3 ± 6.4, P < 0.05) and PMN from peripheral blood in wt (0.5 ± 0.1 vs 10.4 ± 0.7, P < 0.05), but not in MMP-9-deficient animals. The MMP-9 activity was also up-regulated by TNF-α in epithelial intestinal cells (2.5 ± 0.5 vs 14.7 ± 3.0, P < 0.05). Although colitis also led to increase of TIMP-1 activity, the MMP-9/TIMP-1 balance remained elevated. Finally, in the MMP-9-deficient colitic mice both the extent and severity of intestinal epithelialinjury were significantly attenuated when compared with wt mice. CONCLUSION: We conclude that DSS induced colitis is markedly attenuated in animals lacking MMP-9. This suggests that intestinal injury induced by DSS is modu-lated by MMP-9 and that inhibition of this gelatinase may reduce inflammation.

关键词： Matrix metalloproteinases MMP-9-deficient Dextran sodium sulphate Inflammatory bowel disease Experimental colitis

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Non-thermal plasma for exhaust gases treatment

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Frontiers of Mechanical Engineering 2015年第3期10卷 301-305页

作者： Elvia ALVA R. Marquidia PACHECO P.l Fernando GOMEZ B. Joel PACHECO P. Arturo COLIN C Victor SANCHEZ-MENDIETA Ricardo VALDIVIA B alfredo santana D. Jose HUERTAS C Hilda FRIAS P. Instituto Nacional de Investigaciones Nucleates Ocoyoacac 52750Mexico Universidad Autonoma del Estado de Mexico Toluca 50000 Mexico Instituto Tecnologico y de Estudios Superiores de Monterrey CampusToluca 50110 Mexico

This article describes a study on a non-thermal plasma device to treat exhaust gases in an internal combustion engine. Several tests using a plasma device to treat exhaust gases are conducted on a Honda GX200- 196 cm3 engine at different rotational speeds. A plasma reactor could be efficient in degrading nitrogen oxides and particulate matter. Monoxide and carbon dioxide treatment is minimal. However, achieving 1%-3% degradation may be interesting to reduce the emission of greenhouse gases.

关键词： plasma treatment NOx CO CO2 particulatematter vehicle

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Photomechanical Ablation of 304L Stainless Steel, Aluminum Oxide (Al₂O₃) Thin Film, and Pure Silicon

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Optics and Photonics Journal 2016年第10期6卷 275-288页

作者： Gabriel de la Rosa-santana Jose alfredo Alvarez-Chavez Hector R. Morano-Okuno Angel J. Morales-Ramirez Esmeralda Uribe Instituto Tecnologico y de Estudios Superiores de Monterrey Campus Estado de Mexico Atizapan de Zaragoza Mexico Instituto Politecnico Nacional-Centro de Investigacion e InnovacionTecnologica (CIITEC-IPN) Mexico City Mexico Instituto Tecnologico y de Estudios Superiores de Monterrey Campus Queretaro Santiago de Queretaro Mexico

Recently, a number of studies have focused on micro-manufacturing processes, which find use in a variety of applications, including the production of microelectromechanical systems (MEMS). The process of ablation in materials is mainly governed by the laser source and scanning speed. The rate of material ablation is influenced by chemical and physical properties. In this work, the energy from a CO2 laser was used to ablate three different materials, namely, stainless steel 304L, a thin film of amorphous aluminum oxide (Al2O3), and pure silicon, due to their wide use in MEMS technology. The laser parameters used were an average power of 18 W and a spot size of 200 μm. The maximum depth during the photomechanical ablation process was 72 μm in the case of 304L steel and 77 μm in the case of the Al2O3 thin film for a scan rate of 24 mm/min. However, at the same scan rate, silicon did not exhibit any penetration. As expected, while increasing scanning speed the ablation depth decreases due to reduced interaction time between laser and material. The theoretical ytterbium fiber laser shown in this study can thus be employed in the manufacturing of a wide variety of materials used in the production of MEMS as well as those used in clean energy technologies.

关键词： Laser Ablation MEMS Ytterbium-Doped Fiber Laser Thin Film

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Production Optimization of Biodiesel from Frying Oil Waste to Reduce the Environmental Impacts

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Journal of Chemistry and Chemical Engineering 2014年第6期8卷 621-625页

作者： Silvério Catureba da Silva Filho Thadeu alfredo Farias Silva Arthur de Queiroz e Silva Amanda Carvalho Miranda Felipe Araájo Calarge José Carlos Curvelo santana Elias Basile Tambourgi Laboratory of Processes and Quality Control Nine July University Sao Paulo 05001-100 Brazil School of Chemical Engineering State University of Campinas Campinas 13083-852 Brazil

The objective of this study was to reduce the environmental impacts of used frying oil waste through the production of biodiesel. A 22 factorial planning has been used to evaluate the influences of alcohol/oil and reaction time on the biodiesel production yield. The optimal condition to produce the biodiesel has been found by use of the response surface methodology and analysis of variance to obtain the fitting model. This study was conducted in Campinas city, Brazil, where were collected the waste oil. An analysis of ecological cost also has been developed. Cooking oils collected from Campinas homes were mixed with ethanol in planned proportions （1：9, 1：7 and 1：5） and were transesterified at 60 ℃ and planned reaction times （30, 60 or 90 min）, in order to obtain biodiesel, using 0.1% NaOH as a catalyst. The results of the physical-chemical analyses demonstrated that the biodiesels obtained possessed characteristics close to those required by Brazilian standards. This fuel could be used in fleets of buses, trucks and machines, or even sold to fuel distributors, which results in a solving between US$0.8 and US$4.5 millions. Thus, Campinas would gain environmental credits and become a sustainable city.

关键词： Biodiesel ecological cost accounting factorial planning frying oil waste.

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短皮革纤维化学改性生产类似皮革复合物 I：乳液聚合化学改性

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北京皮革（中外皮革信息版）（中） 2008年第11期 105-110页

作者： T．J．MADERA-santana M．J．AGUILAR-VEGA alfredo MARQUEZ-LUCERO 龚英（译）

为评估利用短革纤维生产类似皮革复合物的可能性，将5kg皮革纤维（从皮革废弃物中提取的）通过甲基丙烯酸甲酯原位乳液聚合方式改性。采取这种改性方法是为了增加皮革纤维与一些用于鞋和毛皮工业的聚合物的相容性。通过氧化还原体系（... 详细信息

为评估利用短革纤维生产类似皮革复合物的可能性，将5kg皮革纤维（从皮革废弃物中提取的）通过甲基丙烯酸甲酯原位乳液聚合方式改性。采取这种改性方法是为了增加皮革纤维与一些用于鞋和毛皮工业的聚合物的相容性。通过氧化还原体系（过硫酸钾／偏亚硫酸氢钠）引发的水$HSL液聚合进行改性。考察了单体浓度、氧化还原引发剂浓度以及反应温度对反应的影响。采用红外光谱（IR）、差示扫描量热仪（DSC）、热重分析（TGA）、X-射线衍射和扫描电镜（SEM）这些测试方法表征了改性后皮革纤维。研究结果表明在胶原纤维间（沉积的方式）以及胶原纤维束内（通过接枝或形成互穿网络结构的方式）形成了聚合物。这种改性方法明显改进了皮革纤维的热稳定性。由于皮革纤维表面形成了聚甲基丙烯酸甲酯涂层（这已经为显微分析方法证实），皮革纤维的水吸附能力降低。在某些应用方面，吸水能力降低这个性能是有利的。

关键词：皮革废弃物纤维生产化学改性乳液聚合复合物类似聚甲基丙烯酸甲酯氧化还原体系

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Molecular phylogeny, morphology, pigment chemistry and ecology in Hygrophoraceae (Agaricales)

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Fungal Diversity 2014年第1期64卷 1-99页

作者： D.Jean Lodge Mahajabeen Padamsee P.Brandon Matheny M.Catherine Aime Sharon A.Cantrell David Boertmann Alexander Kovalenko alfredo Vizzini Bryn T.M.Dentinger Paul M.Kirk A.Martyn Ainsworth Jean-Marc Moncalvo Rytas Vilgalys Ellen Larsson Robert Lücking Gareth W.Griffith Matthew E.Smith Lorelei L.Norvell Dennis E.Desjardin Scott A.Redhead Clark L.Ovrebo Edgar B.Lickey Enrico Ercole Karen W.Hughes Régis Courtecuisse Anthony Young Manfred Binder Andrew M.Minnis Daniel L.Lindner Beatriz Ortiz-santana John Haight Thomas Læssøe Timothy J.Baroni József Geml Tsutomu Hattori Center for Forest Mycology Research Northern Research StationUSDA-Forest ServiceLuquilloPR 00773-1377USA Systematics Team Landcare Research231 Morrin RoadAuckland 1072New Zealand Ecology&Evolutionary Biology University of TennesseeKnoxvilleTN 37996-1610USA Department of Botany&Plant Pathology Purdue UniversityWest LafayetteIN 47907USA Science and Technology Universidad del TuraboGuraboPR 00778-3030USA Department of Bioscience Aarhus UniversityFrederiksborgvej 399DK-4000 RoskildeDenmark Komarov Botanical Institute of the Russian Academy of Sciences 2 Prof.Popov Str.St.Petersburg 197376Russia Dipartimento di Scienze della Vita e Biologia dei Sistemi Universitàdi TorinoViale P.A.Mattioli 2510125 TorinoItaly Mycology Royal Botanic GardensKewRichmondSurrey TW93DSUK Royal Ontario Museum 100 Queen’s ParkTorontoONCanada Biology Department Duke UniversityDurhamNC 27708-0338USA Biological&Environmental Sciences University of GothenburgGöteborgSweden Science&Eduaction Integrative Research&Collections(Botany)The Field Museum of Natural History1400 Lake Shore Dr.ChicagoIL 60605-2496USA University of Wales AberystwythCeredigion SY233DDUK Department of Plant Pathology University of FloridaGainesvilleFL 32611-0680USA Pacific Northwest Mycology Service 6720 NW Skyline BvdPortlandOR 97229-1309USA Department of Biology San Francisco State University1600 Holloway Ave.San FranciscoCA 94132USA National Mycological Herbarium(DAOM) Science and Technology BranchAgriculture&Agri-FoodsCanada960 Carling AvenueOttawaOntarioCanada ONT K1A 0C6 Department of Biology University of Central OklahomaEdmondOK 73034USA Department of Biology Bridgewater College402 E.College St.BridgewaterVA 22812USA Department of Botany Faculty of Pharmaceutical&Biological SciencesLilleFrance 100 Langton Road BlackbuttQld 4306Australia CBS Fungal Biodiversity Centre Evolutionary PhytopathologyInst.of the Royal Netherlands Academy of Arts&Sciences(KNAW)Uppsalalaan 83584 CT UtrechtThe Netherlands

Molecular phylogenies using 1–4 gene regions and information on ecology,morphology and pigment chemistry were used in a partial revision of the agaric family *** phylogenetically supported genera we recognize here in the Hygrophoraceae based on these and previous analyses are:Acantholichen,Ampulloclitocybe,Arrhenia,Cantharellula,Cantharocybe,Chromosera,Chrysomphalina,Cora,Corella,Cuphophyllus,Cyphellostereum,Dictyonema,Eonema,Gliophorus,Haasiella,Humidicutis,Hygroaster,Hygrocybe,Hygrophorus,Lichenomphalia,Neohygrocybe,Porpolomopsis and Pseudoarmillariella.A new genus that is sister to Chromosera is described as *** were made at the ranks of subfamily,tribe,genus,subgenus,section and *** present three new subfamilies,eight tribes(five new),eight subgenera(one new,one new combination and one ***.),26 sections(five new and three new combinations and two ***.)and 14 subsections(two new,two ***.).Species of Chromosera,Gliophorus,Humidicutis,and Neohygrocybe are often treated within the genus Hygrocybe;we therefore provide valid names in both classification *** used a minimalist approach in transferring genera and creating new names and ***,we retain in the Hygrophoraceae the basal cuphophylloid grade comprising the genera Cuphophyllus,Ampulloclitocybe andCantharocybe,despite weak phylogenetic *** include Aeruginospora and Semiomphalina in Hygrophoraceae based on morphology though molecular data are *** lower hygrophoroid clade is basal to Hygrophoraceae s.s.,comprising the genera Aphroditeola,Macrotyphula,Phyllotopsis,Pleurocybella,Sarcomyxa,Tricholomopsis and Typhula.

关键词： Hygrophoraceae Fungi Revisionary systematics Nomenclatural revision Phylogenetics Pigment chemistry Lamellar trama construction Hymenial morphology Ecology

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Fungal diversity notes 253-366:taxonomic and phylogenetic contributions to fungal taxa

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Fungal Diversity 2016年第3期78卷 1-237页

作者： Guo Jie Li Kevin D.Hyde Rui Lin Zhao Sinang Hongsanan Faten Awad Abdel-Aziz Mohamed A.Abdel-Wahab Pablo Alvarado Genivaldo Alves-Silva Joseph F.Ammirati Hiran A.Ariyawansa Abhishek Baghela Ali Hassan Bahkali Michael Beug D.Jayarama Bhat Dimitar Bojantchev Thitiya Boonpratuang Timur S.Bulgakov Erio Camporesi Marcela CBoro Oldriska Ceska Dyutiparna Chakraborty Jia Jia Chen K.W.Thilini Chethana Putarak Chomnunti Giovanni Consiglio Bao Kai Cui Dong Qin Dai Yu Cheng Dai Dinushani A.Daranagama Kanad Das Monika C.Dayarathne Eske De Crop Rafael J.V.De Oliveira Carlos Alberto Fragoso de Souza JoséIde Souza Bryn T.M.Dentinger Asha J.Dissanayake Mingkwan Doilom E.Ricardo Drechsler-Santos Masoomeh Ghobad-Nejhad Sean P.Gilmore Aristóteles Góes-Neto MichałGorczak Charles H.Haitjema Kalani Kanchana Hapuarachchi Akira Hashimoto Mao Qiang He John K.Henske Kazuyuki Hirayama Maria J.Iribarren Subashini C.Jayasiri Ruvishika S.Jayawardena Sun Jeong Jeon Gustavo H.Jerônimo Ana L.Jesus E.B.Gareth Jones Ji Chuan Kang Samantha C.Karunarathna Paul M.Kirk Sirinapa Konta Eric Kuhnert Ewald Langer Haeng Sub Lee Hyang Burm Lee Wen Jing Li Xing Hong Li Kare Liimatainen Diogo Xavier Lima Chuan Gen Lin Jian Kui Liu Xings Zhong Liu Zuo Yi Liu J.Jennifer Luangsa-ard Robert Lücking H.Thorsten Lumbsch Saisamorn Lumyong Eduardo M.Leaño Agostina V.Marano Misato Matsumura Eric H.C.McKenzie Suchada Mongkolsamrit Peter E.Mortimer Thi Thuong Thuong Nguyen Tuula Niskanen Chada Norphanphoun Michelle A.O’Malley Sittiporn Parnmen Julia Pawłowska Rekhani H.Perera Rungtiwa Phookamsak Chayanard Phukhamsakda Carmen L.A.Pires-Zottarelli Olivier Raspé Mateus A.Reck Sarah C.O.Rocha AndréL.C.M.Ade Santiago Indunil C.Senanayake Ledo Setti Qiu Ju Shang Sanjay K.Singh Esteban B.Sir Kevin V.Solomon Jie Song Prasert Srikitikulchai Marc Stadler Satinee Suetrong Hayato Takahashi Takumasa Takahashi Kazuaki Tanaka Li Ping Tang Kasun M.Thambugala Donnaya Thanakitpipattana Michael K.Theodorou Benjarong Thongbai Tuksaporn Thummarukcharoen Qing Tian Saowaluck Tibpromma Annemieke State Key Laboratory of Mycology Institute of MicrobiologyChinese Academy of SciencesNo 31st West Beichen RoadChaoyang DistrictBeijing 100101People’s Republic of China Centre of Excellence in Fungal Research and School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of ScienceKunming 650201YunnanPeople’s Republic of China Department of Botany and Microbiology College of ScienceKing Saud UniversityP.O.Box:2455Riyadh 1145Saudi Arabia Department of Botany and Microbiology Faculty of ScienceSohag UniversitySohag 82524Egypt ALVALAB C/La Rochela nº47E-39012 SantanderSpain Micolab Programa de Pós-Graduação em Biologia de FungosAlgas e PlantasDepartamento de BotânicaUniversidade Federal de Santa CatarinaCampus Universitário TrindadeCEP:88040-900 FlorianópolisSanta CatarinaBrazil Department of Biology University of WashingtonBox 351800SeattleWA 98195-1800USA Guizhou Key Laboratory of Agricultural Biotechnology Guizhou Academy of Agricultural SciencesGuiyang 550006GuizhouPeople’s Republic of China National Fungal Culture Collection of India(NFCCI) Biodiversity and Palaeobiology GroupMACS’Agharkar Research InstituteG.G.Agarkar RoadPune 411004India PO Box 116 HusumWA 98623-0116USA Formerly Department of BotanyGoa UniversityGoaIndia No.128/1-J Azad Housing SocietyCurcaP.O.Goa Velha 403108India *** 345 Shipwatch LaneHerculesCA 94547USA Microbe Interaction Laboratory(BMIT) BIOTECNational Science and Technology Development Agency(NSTDA)113 Thailand Science ParkThanon PhahonyothinTombon Khlong NuengAmphoeKhlong LuangPathum Thani 12120Thailand Academy of Biology and Biotechnology Southern Federal UniversityRostov-on-Don 344090Rostov regionRussia A.M.B.Gruppo Micologico Forlivese BAntonio“Cicognani” Via Roma Forlì Italy 18 A.M.B.Circolo Micologico“Giovanni Carini”C.P.314BresciaItaly Societàper gli Studi Naturalistici della Romagna C.P.144Bagnacavallo

Notes on 113 fungal taxa are compiled in this paper,including 11 new genera,89 new species,one new subspecies,three new combinations and seven reference *** geographic and taxonomic range of fungal taxa are *** the Ascomycota the new genera Angustospora(Testudinaceae),Camporesia(Xylariaceae),Clematidis,Crassiparies(Pleosporales genera incertae sedis),Farasanispora,Longiostiolum(Pleosporales genera incertae sedis),Multilocularia(Parabambusicolaceae),Neophaeocryptopus(Dothideaceae),Parameliola(Pleosporales genera incertae sedis),and Towyspora(Lentitheciaceae)are *** introduced species are Angustospora nilensis,Aniptodera aquibella,Annulohypoxylon albidiscum,Astrocystis thailandica,Camporesia sambuci,Clematidis italica,Colletotrichum menispermi,***,Comoclathris pimpinellae,Crassiparies quadrisporus,Cytospora salicicola,Diatrype thailandica,Dothiorella rhamni,Durotheca macrostroma,Farasanispora avicenniae,Halorosellinia rhizophorae,Humicola koreana,Hypoxylon lilloi,Kirschsteiniothelia tectonae,Lindgomyces okinawaensis,Longiostiolum tectonae,Lophiostoma pseudoarmatisporum,Moelleriella phukhiaoensis,***,Mucoharknessia anthoxanthi,Multilocularia bambusae,Multiseptospora thysanolaenae,Neophaeocryptopus cytisi,Ocellularia arachchigei,***,Ochronectria thailandica,Ophiocordyceps karstii,Parameliola acaciae,***,Parastagonospora cumpignensis,Pseudodidymosphaeria phlei,Polyplosphaeria thailandica,Pseudolachnella brevifusiformis,Psiloglonium macrosporum,Rhabdodiscus albodenticulatus,Rosellinia chiangmaiensis,Saccothecium rubi,Seimatosporium pseudocornii,***,Sigarispora ononidis and Towyspora *** combinations are provided for Eutiarosporella dactylidis(sexual morph described and illus trated)and Pseudocamarosporium ***,illustrations and/or reference specimens are designated for Aposphaeria corallinolutea,Cryptovalsa ampelina,Dothiorella vidmadera,Ophiocordyceps formosana,P

关键词： Ascomycota Basidiomycota Neocallimastigomycota Oomycota.Zygomycota Phylogeny Taxonomy New genus New species

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