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高冲击下的保护:清除西墨西哥岛屿外来哺乳动物

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AMBIO－人类环境杂志 2008年第2期37卷 97-103页

作者： alfonso aguirre-muoz Donald A.Croll C.Josh Donlan R.William Henry Ⅲ Miguel Angel Hermosillo Gregg R.Howald Bradford S.Keitt Luciana Luna-Mendoza Marlenne Rodríguez-Malagón Luz María Salas-Flores Araceli Samaniego-Herrera Jose Angel Sanchez-Pacheco Jacob Sheppard Bernie R.Tershy Jorge Toro-Benito Shaye Wolf Bill Wood 寒江 Grupo de Ecologíay Conservación de Islas 岛屿保护组织(IC) 高级保护战略(Advanced Conservation Strategies) 加州大学圣克鲁兹分校 IC-Canada IC Grupo de Ecología y Conservación de Islas 墨西哥联邦政府内务部

岛屿蕴含着与其面积不成比例的地球生物多样性,但是,岛屿生物多样性有很大一部分丧失了,这很大程度上是由于外来哺乳动物的冲击。幸运的是,倘若有强有力的手段防止生物灭绝、重建生态系统,那么,可以例行地清除岛屿上的外来哺乳动物。鉴... 详细信息

岛屿蕴含着与其面积不成比例的地球生物多样性,但是,岛屿生物多样性有很大一部分丧失了,这很大程度上是由于外来哺乳动物的冲击。幸运的是,倘若有强有力的手段防止生物灭绝、重建生态系统,那么,可以例行地清除岛屿上的外来哺乳动物。鉴于目前超过80%的世界主要岛群存在外来哺乳动物并且它们构成了对地球生物多样性的首要威胁,推广可重现的、可依比例缩放的行动模式以清除岛屿外来哺乳动物便十分重要了。这里我们报告过去10年来应用于西墨西哥群岛的一种成功的行动模式。非政府组织、理论生物学家、墨西哥政府机构,以及当地个人在3个群岛海进行了通力合作,产生了重大的重建成效。从26个岛屿清除了42个外来哺乳动物种群。对于每一生物群体(colony)花费21 615美元,每一分类(taxon)花费49 370美元,分别有201个海鸟群体、88个陆地特有分类得到了保护。这些保护行动的成功要归功于一种可操作的行动模式,它有3个主要的构成部分:1)将研究、重点设定、资助、公众教育、政策制定、能力建设、保护行动、监测及评估结合在一起的三国通力协作;2)主动的、专门的自然资源管理机构;3)墨西哥和美国学术研究人员的有效参与。现在需要的是:一份将所需的额外资助、能力、技术进步及政策问题综合起来的,本地区其余岛屿清除外来哺乳动物的详细计划。西墨西哥的岛屿保护提供了一种有效的方法,这种方法可以很容易地应用于其它保护努力十分有限的多岛海区域。

关键词：哺乳动物墨西哥岛屿保护清除高冲击生物多样性比例缩放

HOP co-chaperones contribute to GA signaling by promoting the accumulation of the F-box protein SNE in Arabidopsis

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Plant Communications 2023年第3期4卷 244-257页

作者： Silvina Mangano alfonso muñoz Lourdes Fernández-Calvino M.Mar Castellano Centro de Biotecnología y Genómica de Plantas Universidad Politécnica de Madrid(UPM)-Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria(INIA/CSIC)Campus Montegancedo UPM28223 Pozuelo de Alarcón(Madrid)Spain Fundación Instituto Leloir and Instituto de Investigaciones Bioquímicas de Buenos Aires(IIBA CONICET)Av.Patricias Argentinas 435Buenos Aires C1405BWEArgentina Departamento de Botánica Ecologíay Fisiología VegetalCampus de RabanalesEdificio Severo OchoaUniversidad de Córdoba14071 CórdobaSpain

Gibberellins(GAs)play important roles in multiple developmental processes and in plant response to the *** the GA pathway,a central regulatory step relies on GA-dependent degradation of the DELLA transcriptional ***,the relevance of the stability of other key proteins in this pathway,such as SLY1 and SNE(the F-box proteins involved in DELLA degradation),remains ***,we take advantage of mutants in the HSP70-HSP90 organizing protein(HOP)co-chaperones and reveal that these proteins contribute to the accumulation of SNE in ***,HOP proteins,along with HSP90 and HSP70,interact in vivo with SNE,and SNE accumulation is significantly reduced in the hop ***,greater accumulation of the DELLA protein RGA is observed in these *** agreement with these molecular phenotypes,hop mutants show a hypersensitive response to the GA inhibitor paclobutrazol and display a partial response to the ectopic addition of GA when GA-regulated processes are *** mutants also display different phenotypes associated with alterations in the GA pathway,such as reduced germination rate,delayed bolting,and reduced hypocotyl elongation in response to warm ***,ectopic overexpression of SNE reverts the delay in germination and the thermally dependent hypocotyl elongation defect of the hop1 hop2 hop3 mutant,revealing that SNE accumulation is the key aspect of the hop mutant ***,these data reveal a pivotal role for HOP in SNE accumulation and GA signaling.

关键词： HSP70-HSP90 organizing protein seed germination thermomorphogenesis RGA protein folding protein stability

A case report of cutaneous larva migrans in a Mexican population of high marginalization

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Asian Pacific Journal of Tropical Biomedicine 2014年第9期4卷 755-756页

作者： Isaac aguirre Maldonadoa Silvia Cruz Duartea Felipe Gonzlez Velzqueza alfonso Alexander Aguilerab Escuela de Medicina Universidad Cristbal Coln.Carr.Veracruz-Medellin s/n.Col.Puente MorenoBoca del RíoVer.94271.Mxico Facultad de Bioanlisis Universidad Veracruzana.Carmn Serdan s/nCol.Flores MagnVeracruzVer.91700.Mxico

The creeping verminous dermatitis or cutaneous larva migrans is a parasitosis caused by percutaneous penetration and migration of larval nematode parasites characterized by producing one or more serpiginous erythematous,indurated,raised and pruritic *** most common cause of cutaneous larva migrans is the Ancytostoma braziliensc located in warm climate *** the present study,authors reported a case of cutaneous larva migrans with a characteristic clinical picture:erythematous-papnlar and vesicular lesion and serpiginous path,with progressive,and pruritic growth and it shown that a living area with immigration,tropical weather conditions and poverty may lead to this common infection.

关键词： Larva migrans Pruritic Purple vesicle Serpiginous Dermatology lesion

Rheological and tribological approaches as a tool for the development of sustainable lubricating greases based on nano-montmorillonite and castor oil

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Friction 2021年第2期9卷 415-428页

作者： Jose Enrique MARTÍN-alfonso María Jose MARTÍN-alfonso Concepción VALENCIA María Teresa CUBERES Department of Chemical Engineering and Materials Science Campus de“El Carmen”University of HuelvaChemical Product and Process Technology Research Center(Pro2TecS)Huelva 21071Spain Department of Applied Mechanics and Project Engineering University of Castilla-La ManchaAlmadén 13400Spain

This study investigates the development of novel montmorillonite/castor oil blends to formulate sustainable lubricating greases to promote the replacement of petrochemicals industry-derived materials by substances obtained from renewable ***,the effect of the thickener concentration on the rheological,chemical,thermal,tribological properties,and atomic force microscopy(AFM)microstructure of these systems were *** results showed that the C20A nanoclay content could be used to modulate the viscosity values,the linear viscoelastic functions,and tribological properties of these montmorillonite *** general,these gel-like dispersions exhibited remarkable lubricant properties;the samples showed values of the friction coefficient and wear scars similar or lower than those obtained with model bentonite grease.

关键词： lubricating greases nanoclay vegetable oil rheology tribology

Emergence of bariatric psychiatry as a new subspecialty

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World Journal of Psychiatry 2022年第1期12卷 108-116页

作者： alfonso Troisi Department of Systems Medicine University of Rome Tor VergataRome 00133Italy

Bariatric surgery is the branch of surgery aimed at helping a person with obesity lose *** implementation of surgical treatment of obesity is growing at an impressive *** expected,the expanding implementation of bariatric procedures has progres-sively revealed critical issues that were not evident when the number of obese patients treated with surgery was relatively *** critical issue is the importance of mental health assessment and care of bariatric *** aim of this review is to provide readers with an up-to-date summary of the goals,methods,and clinical strategies of bariatric *** aims can be grouped into three distinct ***,to ascertain that there are no psychiatric contraindications to safe bariatric ***,to diagnose and treat pre-surgery mental conditions that could predict poor weight ***,to diagnose and treat post-surgery mental conditions associated with poor quality of *** bariatric psychiatry has gained the status of a new subspecialty within the field of mental health and psychopathology,many clinical questions remain *** need more long-term data on outcome measures such as quality of life,adherence to behavioral guidelines,risk of suicide,and postsurgery prevalence of psychological disturbances and mental disorders.

关键词： Bariatric surgery Psychiatry Weight loss Mental health Quality of life Preoperative assessment Postoperative follow-up

Genetics of adult attachment and the endogenous opioid system

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World Journal of Psychiatry 2022年第8期12卷 1105-1107页

作者： alfonso Troisi Department of Systems Medicine University of Rome Tor VergataRome 00133Italy

Since the pioneering work by Panksepp et al,the neurobiological bases of attachment behavior have been closely linked with opioid *** gene studies of adult individuals have shown that variation in the muopioid receptor gene(OPRM1)influences attachment *** maternal care and the A/A genotype of the A118G polymorphism interact in modulating levels of fearful *** to their counterparts carrying the A/A genotype,individuals expressing the minor 118G allele show lower levels of avoidant attachment and experience more pleasure in social *** imaging research has strengthened the biological plausibility of candidate gene *** avoidance dimension of attachment correlates negatively with muopioid receptor availability in the thalamus and anterior cingulate cortex,as well as the frontal cortex,amygdala,and ***,findings from human studies combined with those from animal models suggest that research on the genetic bases of attachment should include the endogenous opioid system among the investigated variables.

关键词： Genetics Avoidant attachment Fearful attachment Endogenous opioids OPRM1 A118G polymorphism

An innovative heterogeneous transfer learning framework to enhance the scalability of deep reinforcement learning controllers in buildings with integrated energy systems

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Building Simulation 2024年第5期17卷 739-770页

作者： Davide Coraci Silvio Brandi Tianzhen Hong alfonso Capozzoli Politecnico di Torino Department of EnergyTEBE research groupBAEDA Lab.Corso Duca degli Abruzzi 24Torino10129Italy Building Technology and Urban Systems Division Lawrence Berkeley National LaboratoryOne Cyclotron RoadBerkeleyCA 94720USA

Deep Reinforcement Learning(DRL)-based control shows enhanced performance in the management of integrated energy systems when compared with Rule-Based Controllers(RBCs),but it still lacks scalability and generalisation due to the necessity of using tailored models for the training *** Learning(TL)is a potential solution to address this ***,existing TL applications in building control have been mostly tested among buildings with similar features,not addressing the need to scale up advanced control in real-world scenarios with diverse energy *** paper assesses the performance of an online heterogeneous TL strategy,comparing it with RBC and offline and online DRL controllers in a simulation setup using EnergyPlus and *** study tests the transfer in both transductive and inductive settings of a DRL policy designed to manage a chiller coupled with a Thermal Energy Storage(TES).The control policy is pre-trained on a source building and transferred to various target buildings characterised by an integrated energy system including photovoltaic and battery energy storage systems,different building envelope features,occupancy schedule and boundary conditions(e.g.,weather and price signal).The TL approach incorporates model slicing,imitation learning and fine-tuning to handle diverse state spaces and reward functions between source and target *** show that the proposed methodology leads to a reduction of 10% in electricity cost and between 10% and 40% in the mean value of the daily average temperature violation rate compared to RBC and online DRL ***,online TL maximises self-sufficiency and self-consumption by 9% and 11% with respect to ***,online TL achieves worse performance compared to offline DRL in either transductive or inductive ***,offline Deep Reinforcement Learning(DRL)agents should be trained at least for 15 episodes to reach the same level of performance as the online

关键词： transfer learning reinforcement learning building control building energy management

A dark vector resonance at CLIC

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Chinese Physics C 2019年第6期43卷 6-13页

作者： Constanza Callender alfonso R.Zerwekh Departamento de Física Universidad Técnica Federico Santa María and Centro Científico-Tecnológico de Valparaíso

One of the main problems in particle physics is to understand the origin and nature of dark matter. An exciting possibility is to consider that dark matter belongs to a new complex but hidden sector. In this paper, we assume the existence of a strongly interacting dark sector consisting of a new scalar doublet and new vector resonances,in accordance with the model recently proposed by our group. Since it was found in the previous work that it is very challenging to find the new vector resonances at the LHC, here we study the possibility of finding them at the future Compact Linear Collider(CLIC) running at■= 3 TeV. We consider two distinct scenarios. In the first, when the non-standard scalars are heavy, the dark resonance is intense enough to make its discovery possible at CLIC when the resonance mass is in the range [2000, 3000] GeV. In the second scenario, when the non-standard scalars are light, the new vector boson is too broad to be recognized as a resonance, and is not detectable except when the mass of the scalars is close to(but smaller than) half of the resonance mass and the scale of the dark sector is high. In all positive cases, less than a tenth of the maximum integrated luminosity is needed to reach the discovery level. Finally, we also comment on the mono-Z production.

关键词： vector res on ance dark matter CLIC

Target Capturing in an Ellipsoidal Region for a Swarm of Double Integrator Agents

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IEEE/CAA Journal of Automatica Sinica 2022年第5期9卷 801-811页

作者： Antonio Bono Luigi D'alfonso Giuseppe Fedele Veysel Gazi IEEE Department of Informatics ModelingElectronics and Systems EngineeringUniversity of CalabriaRende 87036Italy Dept.Electrical and Electronics Eng. Faculty of EngineeringMarmara UniversityIstanbul 34722 Department of Control and Automation Engineering Faculty of Electrical and Electronics EngineeringYildiz Technical UniversityEsenler 34220Turkey

In this paper we focus on the target capturing problem for a swarm of agents modelled as double integrators in any finite space *** agent knows the relative position of the target and has only an estimation of its velocity and *** that the estimation errors are bounded by some known values,it is possible to design a control law that ensures that agents enter a user-defined ellipsoidal ring around the moving *** know the relative position of the other members whose distance is smaller than a common detection ***,in the case of no uncertainty about target data and homogeneous agents,we show how the swarm can reach a static configuration around the moving *** simulations are reported to show the effectiveness of the proposed strategy.

关键词： Agents-based systems cooperative control swarms target-capturing