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Decline and fall of aging astrocytes:the human perspective

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Neural Regeneration Research 2025年第6期20卷 1713-1714页

作者： Alexei Verkhratsky alexey Semyanov Faculty of Biology Medicine and HealthThe University of ManchesterManchesterUK Department of Neurosciences University of the Basque Country UPV/EHU and CIBERNEDLeioaSpain Department of Forensic Analytical Toxicology School of Forensic MedicineChina Medical UniversityShenyangLiaoning ProvinceChina Department of Stem Cell Biology State Research Institute Centre for Innovative MedicineVilniusLithuania International Collaborative Center on Big Science Plan for Purinergic Signalling Chengdu University of Traditional Chinese MedicineChengduSichuan ProvinceChina Department of Physiology Jiaxing University College of MedicineJiaxingZhejiang ProvinceChina

“Last scene of all that ends this strange,eventful history,is second childishness and mere oblivion.I am sans teeth,sans eyes,sans taste,sans everything.”William Shakespeare‘As You Like It'Act 2,Sc.7,l.139Aging of the human brain is characterized by a progressive decline of its functional capacity;this decline however varies widely,and cognitive longevity differs substantially between individuals.

关键词： aging teeth progressive

On Splitting of the Normalizer of a Maximal Torus in E6(q)

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Algebra Colloquium 2019年第2期26卷 329-350页

作者： alexey Galt alexey Staroletov Sobolev Institute of Mathematics Novosibirsk Russia

Let G be a finite group of Lie type E6 over Fq (adjoint or simply connected) and W be the Weyl group of G. We describe maximal tori T such that T has a complement in its algebraic normalizer N(G, T). It is well known that for each maximal torus T of G there exists an element w ∈ W such that N(G, T )/T ■ CW(w). When T does not have a complement isomorphic to CW(w), we show that w has a lift in N(G, T) of the same order.

关键词： finite group of Lie type maximal torus algebraic normalizer split extension

Sheared peridotite xenolith from the *** kimberlite pipe,Arkhangelsk Diamond Province,Russia:Texture,composition,and origin

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Geoscience Frontiers 2017年第4期8卷 653-669页

作者： alexey vladimirovich Kargin Lyudmila Vyacheslavovna Sazonova Anna Andreevna Nosova Vladimir Anatolievich Pervov Elena Vladimirovna Minevrina Vladimir Anatolievich Khvostikov Zhanna Petrovna Burmii Institute of Geology of Ore Deposits PetrographyMineralogyand GeochemistryRussian Academy of Sciences(IGEM RAS) Lomonosov Moscow State University Departamento de Geologia.Sociedade Mineira de Catoca Institute of Technological Problems of Microelectronics and Ultrapure Materials Russian Academy of Sciences

The petrography and mineral composition of a mantle-derived garnet peridotite xenolith from the *** kimberlite pipe（Arkhangelsk Diamond Province,Russia） was *** on petrographic characteristics,the peridotite xenolith reflects a sheared *** sheared peridotite experienced a complex evolution with formation of three main mineral assemblages：（1） a relict harzburgite assemblage consist of olivine and orthopyroxene porphyroclasts and cores of garnet grains（Gar1） with sinusoidal rare earth elements（REE） chondrite C1 normalized patterns;（2） a neoblastic olivine and orthopyroxene assemblage;（3） the last assemblage associated with the formation of clinopyroxene and garnet marginal zones（Gar2）.Major and trace element compositions of olivine,orthopyroxene,clinopyroxene and garnet indicate that both the neoblast and clinopyroxene-Gar2 mineral assemblages were in equilibrium with a high Fe-Ti carbonate-silicate metasomatic *** nature of the metasomatic agent was estimated based on high field strength elements（HFSE） composition of olivine neoblasts,the garnet-clinopyroxene equilibrium condition and calculated by REE-composition of Gar2 and *** these evidences indicate that the agent was a high temperature carbonate-silicate melt that is geochemically linked to the formation of the protokimberlite melt.

关键词： Sheared peridotite Mantle metasomatism Kimberlite Olivine Garnet Clinopyroxene

Normal forms of linear second order partial differential equations on the plane

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Science China Mathematics 2018年第11期61卷 1947-1962页

作者： alexey Davydov Department of Mathematics The National University of Science and Technology MISiS Moscow 119049 Russia Department of Theory of Dynamical Systems Lomonosov Moscow State University Moscow 119991 Russia International Institute for Applied Systems Analysis Laxenburg A-2361 Austria

The paper is devoted to the theory of normal forms of main symbols for linear second order partial differential equations on the *** discuss the results obtained in the last decades and some problems,which are important both for the development of this theory and the *** reduction theorem,which was used to obtain many of recent results in the theory,is included in the paper in the parametric form together with *** is a feeling that the theorem still has potential to get progress in the solution of open problems in the theory.

关键词： normal form mixed type partial differential equation main symbol

Shock-wave impact on the knee joint affected with osteoarthritis and after arthroplasty

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Defence Technology（防务技术） 2023年第2期20卷 1-10页

作者： Galina Eremina alexey Smolin Institute of Strength Physics and Materials Science of Siberian Branch of Russian Academy of Sciences 2/4pr.AkademicheskiiTomsk634055Russia

Degenerative diseases significantly reduce the quality of human ***-invasive treatments are used in the initial stages of osteoarthritis(OA).Total knee arthroplasty is used in the late stages of osteoarthritis of the knee ***-invasive methods based on mechanical action are also used for the rehabilitation of a patient after *** paper presents numerical models of the knee joint with degenerative OA changes and *** these models,a computational study was made of the influence of the intensity of shock-wave exposure on the conditioning for the regeneration of bone and cartilage *** on the modeling results,it was found that in the knee joint with degenerative OA changes,conditions for the regeneration of cartilage and meniscus tissues were fulfilled under medium and highintensity *** high-intensity loading(up to 0.9 m J/mm^(2)),the stress level was significantly below the ultimate value required for *** knee arthroplasty,the conditions for bone tissue regeneration around the tibia component are fulfilled only under high-intensity loading.

关键词： Knee joint Total knee replacement Shock-wave therapy Computer simulation Method of movable cellular automata

Searching For Wide Binary Stars with Non-coeval Components in the Southern Sky

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Research in Astronomy and Astrophysics 2023年第5期23卷 230-235页

作者： alexey Kniazev Oleg Malkov South African Astronomical Observatory Cape Town7935South Africa Southern African Large Telescope Cape Town7935South Africa Special Astrophysical Observatory Nizhnij ArkhyzKarachai-Circassia369167Russia Sternberg State Astronomical Institute MoscowUniversitetsky ave.13Russia Institute of Astronomy Russian Academy of Sciences48 Pyatnitskaya St.Moscow 119017Russia

We have completed our observational program to search for wide binary systems with non-coeval components in the southern sky and report our results *** final set of four systems was spectroscopically investigated in this *** binary systems with components of different ages were found among *** into account our previous studies,we estimate the fraction of such binaries(i.e.,binaries formed,presumably,by capture)to be not higher than 0.06%.The study will be continued on the northern sky.

关键词： (stars:)binaries general-(stars:)binaries visual-stars formation

Quantum information and microscopic measuring instruments

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Communications in Theoretical Physics 2020年第1期72卷 44-51页

作者： alexey V Melkikh Ural Federal University YekaterinburgRussia

The consideration of measuring instruments as macroscopic bodies leads to neglect of the microscopic processes that occur during *** disregard is not justified in general *** an example of measurements using microscopic instruments,the scattering of a photon by an electron with electron interference at two slits(Compton effect)was *** amount of information that can be obtained in such a process is inversely proportional to the wavelength of the incident *** large photon wavelengths(soft measurements),the pure state of the electron can be disrupted by an arbitrarily small extent;accordingly,the amount of information extracted in such an experiment is also arbitrarily *** is shown that the energy price for a bit obtained in such a measurement tends toward a constant value for increasing the photon *** instruments can be used in situations where energy costs for measurements are important.

关键词： measurement problem double-slit experiment Von Neumann entropy decoherence compton effect

MULTIPLE CRITERIA DECISION MAKING： DISCORDANT PREFERENCES AND PROBLEM DESCRIPTION

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Journal of Systems Science and Systems Engineering 2007年第1期16卷 22-33页

作者： alexey B. PETROVSKY Institute for Systems Analysis Russian Academy of Sciences Prospect 60 Let Octyabrya 9 Moscow 117312 Russia

There are many practical decision problems where decision makers＇ preferences may be inconsistent and contradictory. In this paper, new methods for ordering and classifying multi-attribute objects by discordant collective preferences are suggested. These methods are based on the theory of multiset metric spaces. The proposed techniques are applied to ranking companies and a competitive selection of projects, which are estimated by several experts upon multiple qualitative criteria.

关键词： Multiple criteria decision making discordant collective preferences multiset metric space

Convection and Stratification of Temperature and Concentration

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Fluid Dynamics & Materials Processing 2024年第6期20卷 1351-1364页

作者： alexey Fedyushkin Laboratory of Complex Fluid Mechanics Ishlinsky Institute for Problems in Mechanics RASMoscow119526Russia

This study is devoted to an analysis of natural convection and the emergence of delamination in an incompressible fluid encapsulated in a closed region heated from the ***,medium and intensive modes of stationary laminar thermal and thermo-concentration convection are *** is shown that nonlinear flow features can radically change the flow structure and characteristics of heat and mass ***,the temperature and concentration segregation in the center of the square region display a non-monotonic dependence on the Grashof number(flow intensity).The formation of a nonstationary periodic structure of thermal convection in boundary layers and in the core of a convective flow in the closed region is also *** of the formation of countercurrents inside the region with the direction opposite to the main convective flow are ***,the influence of vertical and horizontal vibrations on oscillatory convection is analyzed in detail.

关键词： Natural convection stratification segregation numerical simulation vibrations