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Linear Programming for Optimum PID Controller Tuning

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Applied Mathematics 2014年第6期5卷 886-897页

作者： Edimar J. oliveira Leonardo M. Honorio alexandre H. Anzai Tamara X. soares Federal University of Juiz de Fora Juiz de Fora Brazil

This work presents a new methodology based on Linear Programming (LP) to tune Proportional-Integral-derivative (PID) control parameters. From a specification of a desired output time domain of the plant, a linear optimization system is proposed to adjust the PID controller leading the output signal to stable operation condition with minimum oscillations. The constraint set used in the optimization process is defined by using numerical integration approach. The generated optimization problem is convex and easily solved using an interior point algorithm. Results obtained using familiar plants from literature have shown that the proposed linear programming problem is very effective for tuning PID controllers.

关键词： Linear Programming Optimal Control Interior Point Method PID Tuning

A Risk-Adjusted Retrospective Data Analysis between Younger and Elderly Patients with Acute Coronary Syndromes—Long-Term Prognosis

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Open Journal of Emergency Medicine 2016年第3期4卷 53-61页

作者： alexandre de Matos Soeiro Alyne Pinto Borba Aline Siqueira Bossa Cindel Nogueira Zullino Maria Carolina Feres de Almeida Soeiro Tatiana de Carvalho Andreucci Torres Leal Carlos V. Serrano Múcio oliveira tavares Emergency Care Unit Heart Institute (InCor) University of S&atilde o Paulo Medical School S&atilde o Paulo Brazil

Purpose: To compare the demographic data and outcomes of younger versus elderly patients with acute coronary syndromes. Methods: This was a retrospective data bank analysis study with 966 patients (268 in the younger group (less than 55 years) and 698 in the elderly group (more than 55 years)). Data were obtained about clinical characteristics, angiography, and medication used at hospital and coronary definitive treatment. The primary endpoint was all cause of in-hospital death and combined events. Comparison between groups was made by Anova and Q-square. Multivariative analysis was determined by logistic regression and was considered significative when p derly group. In the younger group 26% was ST-myocardial infarction versus 18% in the elderly group. About 7% of younger patients were submitted to coronary bypass surgery and 42% to percutaneous coronary angioplasty versus 12% and 25% in elderly group, respectively. Significant difference was observed between the younger versus elderly groups in deaths (1.5% × 7.5%, p = 0.004), combined events (14.9% × 26.3%, p = 0.02) and killip III/IV (3.7% × 8.3%, p = 0.04). Long-term mortality was 3.7% × 10.2%, p = 0.01). Conclusions: In patients with acute coronary syndromes age was an important predictor factor of mortality and complications. Significative differences in outcomes were observed between the two groups in-hospital and long-term follow-up.

关键词： Young Elder Acute Coronary Syndrome

Comparison of Two Protocols of Agar Gel Immunodiffusion(AGID)Used to Diagnose of Equine Infectious Anemia(EIA)

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Open Journal of Veterinary Medicine 2015年第7期5卷 169-174页

作者： Maria do Rosario oliveira da Cunha Beltrao Cid Aristoteles de Siqueira Alencar Adriana soares Leite Leonardo tavares Freitas Julianne Cortizo Gonzalez Vania Lucia de Assis Santana Helio Cordeiro Manso-Filho department of Veterinary Medicine Federal Rural University of PernambucoRecifeBrazil National Animal and Plant Laboratory Ministry of AgricultureLivestock and Food SupplyRecifeBrazil

The aim of the present study was to compare two protocols of Agar Gel Immunodiffusion (AGID) that can be used to diagnose Equine Infectious Anemia (EIA). Different volumes of reagents and support for agar gel were used, as recommended by the Ministry of Agriculture, Livestock and Food Supply (MAPA) and the World Organization for Animal Health (OIE). Equidae sera samples (n = 1000) were tested using a national commercial kit and different volumes (i.e. 25 μL—MAPA and 50 μL—OIE) of reagents and standard sera. Antigen was used as recommended by MAPA. The results were assessed by two operators, 48 hours after beginning the test. At the end of the experiment, a Kappa index of 1 was obtained by the operators, for the interpretation of the results and for the different volumes of reagents used. Similar results of agreement (Kappa index = 1) were obtained when using slides or Petri dishes as support for the agar gel. In both cases, an almost perfect agreement was achieved, suggesting that the use of different supports does not affect the results. These findings indicate that both protocols (MAPA and OIE) can be used to diagnose EIA.

关键词： Horses Equids EIA Diagnosis AGID Serology

Monte Carlo Simulations for a Preliminary design of TRIGA IPR-R1 PGAA Facility

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Journal of Chemistry and Chemical Engineering 2016年第6期10卷 256-270页

作者： Bruno Teixeira Guerra alexandre soares Leal Claubia Pereira Maria Angela de Barros Correia Menezes deN (departamento de Engenharia Nuclear) UFMG (Universidade Federal de Minas Gerais) Av. Antonio Carlos 6627 Campus Pampulha CEP 31270 901 Belo Horizonte Minas Gerais Brazil CDTN (Nuclear Technology development Center) CNEN (Brazilian Commission for Nuclear Energy) Av. Antonio Carlos 6627 Campus UFMG CEP 31270 901 Belo Horizonte Minas Gerais Brazil

Brazilian biosafety law and the new breeding technologies

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Frontiers of Agricultural Science and Engineering 2020年第2期7卷 204-210页

作者： alexandre Lima NEPOMUCENO Renata FUGANTI-PAGLIARINI Maria Sueli soares FELIPE Hugo Bruno Correa MOLINARI Edivaldo Domingues VELINI Eduardo Romano de Campos PINTO Maria Lucia Zaidan DAGLI Galdino ANDRAde FILHO Patricia Machado Bueno FERNANdeS Embrapa Soybean Londrina 86001970Brazil Catholic University of Brasilia Brasilia 70790160Brazil Embrapa Agroenergy Biological Station ParkBrasilia 70770901Brazil Paulista State University Julio de Mesquita Filho Botucatu Faculty of Agronomic SciencesBotucatu 18610307Brazil Embrapa Biotechnology and Genetic Resources—Biological Station Park Brasilia 70770900Brazil Sao Paulo University Veterinary FacultySao Paulo 05508900Brazil Londrina State University Microbiology DepartmentUniversity CampusLondrina 86051990Brazil Espirito Santo Federal University Biotechnology Post GraduationVitoria 29040090Brazil CTNBio(National Biosafety Technical Commission) Brasilia 70610200Brazil

Globally,the area of land cultivated with genetically modified(GM)crops has increased a thousand-fold over the last two *** this technology has become important for food production,the regulatory frameworks that underpin these outcomes are based on a list of requirements for a risk assessment that differ from country to *** recent years,policymakers have had the opportunity to learn from the controversies over transgenics to create effective regulatory milestones for emerging technologies,allowing them to reach their potential for a more sustainable agriculture,ensuring food *** Brazil,Law No.11.105 of 24 March 2005 established a framework with four main organizations responsible for risk assessment and ***,most of new breeding technologies did not exist at that time and were not considered in this ***2016,Normative Resolution No.16 of the National Biosafety Technical Commission(CTNBio)was established to address this gap based on the evaluation of the products obtained through these techniques(termed Innovative Precision Improvement Techniques in the resolution),in a case-by-case consultation ***,if the product is designated to be a GM,the developer will have to go through the biosafety requirements and will be approved only after CTNBio risk *** the product is designated not to be GM(for the purposes of the legislation),then it can be registered using the existing ***,152 GM products are commercially approved in *** 2018,CTNBio assessed the first consultation on commercial release of plants generated using the new breeding technologies and has subsequently approved six *** is expected that many institutions would be able to participate in Brazilian and world markets,developing and introducing new biotechnological solutions and products through a more sustainable approach and without facing public disapproval,a common issue for GM crops.

关键词： Brazilian legislation CTNBio genetically modified crops

Prognosis of Patients with Acute Coronary Syndromes and Bleeding—The Importance of Routine Use of a Bleeding Risk Score

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World Journal of Cardiovascular Diseases 2015年第12期5卷 327-334页

作者： alexandre de Matos Soeiro Ricardo Cesar Campos devezae Silva Aline Siqueira Bossa Cindel Nogueira Zullino Tatiana de Carvalho Andreucci Torres Leal Maria Carolina Feres de Almeida Soeiro Carlos V. Serrano Jr. Múcio tavares oliveira Jr. Emergency Unit-Heart Institute University of Sao Paulo Medical School Sao Paulo Brazil

Introduction: Recent studies showed relation between mortality and bleeding in acute coronary syndromes. Objective: The objective is to analyze the prognosis of patients with acute coronary syndromes with or without in-hospital major and/or minor bleedings. Methods: This was a pro-spective data bank analysis study with 546 patients (39 with bleeding (group I) and 507 without bleeding (group II)) with acute coronary syndromes included between May 2010 and May 2013. Besides, Mehran bleeding risk score was calculated to all patients. The primary endpoint was all causes of in-hospital death and combined events. Comparison between groups was made by Anova and Q-square. Multivariate analysis was determined by logistic regression and was considered significant when p p = 0.005) and combined events (35.9% vs 11.4%, p deaths and combined events.

关键词： Unstable Angina Bleeding Acute Myocardial Infarction

Superiority of Prothrombin Complex Concentrate versus Frozen Fresh Plasma in Cardiology Patients with Warfarin Intoxication–Observational Study

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Open Journal of Emergency Medicine 2017年第2期5卷 75-84页

作者： alexandre de Matos Soeiro Maria Cristina César Bruno Biselli Aline Siqueira Bossa T. de Carvalho Andreucci Torres Leal Maria Carolina Feres de Almeida Soeiro Carlos V. Serrano Ludhmila Abra&atilde o Hajjar Múcio tavares oliveira Emergency Unit–Heart Institute–University of S&atilde o Paulo Medical School S&atilde o Paulo Brazil

Objective: The objective of this study was to analyse the reversibility of the anticoagulant effect of warfarin by comparing prothrombin complex concentrate (PCC) versus frozen fresh plasma (FFP) in cardiology patients with serious warfarin intoxication. Methods: This was an observational and retrospective study comprising 67 patients (18 in group I [PCC] and 49 in group II [FFP]). The primary endpoint was the reversal of anticoagulant effect of warfarin after 2 and 24 hours of PCC or FFP administration. Comparisons between the groups were made using T-test and Q-square. Multivariate analyses were conducted using logistic regression, and the results were considered significant when p Results: The medium dose used was 27.6 UI/kg of PCC and 14.5 ml/kg of FFP. Significant differences were observed between groups I and II in the INR reversibility measurements after 2 hours (33.3% vs. 6.1%, p = 0.001) and 24 hours (38.9% vs. 12.2%, p = 0.009) as well as in the occurrence of pulmonary edema (5.6% vs. 42.9%, OR = 11.10, p = 0.04). The AUC for PCC was 0.891 (CI 95% [0.72 - 1.0]), and for FFP, it was 0.291 (CI 95% [0.09 - 0.49]). Conclusions: PCC is better than FFP treatment in reversing the warfarin intoxication after 2 and 24 hours of administration. Furthermore, PCC showed lower pulmonary edema in cardiology patients.

关键词： Intoxication Warfarin Fresh Frozen Plasma Prothrombin Complex Concentrate

Leading for Sustainability in the Brazilian Construction Industry

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Open Journal of Civil Engineering 2016年第5期6卷 737-748页

作者： alexandre Jose Vianna Barbosa de Araujo Ubiratan Rohan Robson Rosa Branco Christine Kowal Chinelli Carlos Alberto Pereira soares Graduate Program in Civil Engineering Fluminense Federal University Niterói Brazil

This article analyzes the major stakeholders in the Brazilian construction industry from the viewpoint of the companies in this sector, as well as how these organizations relate to their stakeholders with regard to the topic of sustainability in the construction. The study was based on the principle that the relationship with stakeholders is one of the foundations for the inception and continuity of activities toward sustainability. The findings of which show that the construction companies start the sustainability implementation process without the involvement of external stakeholders. This survey points out the difficulty faced by Brazilian construction companies in relating to their stakeholders. There is the perception that the customers and other actors do not value sustainability-oriented activities, but, at the same time, the relationship of the companies with these stakeholders is limited to disclosure of information. This characteristic of the industry reveals a need for sustainability projects that take into consideration, since their formulation, the stakeholders’ perceptions. The importance of this article lies in the recognition that, although the topic of sustainability is discussed at all levels, studies that examine how specific construction industries have been dealing with it are still rare.

关键词： Construction Industry Sustainability Environmental Challenges Stakeholders

Barriers and Challenges to the Sustainability Requirements Implementation in Public Procurement of Engineering Works and Services

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Open Journal of Civil Engineering 2017年第1期7卷 1-13页

作者： Clézio Thadeu de Souza Dutra Ubiratan Rohan Robson Rosa Branco Christine Kowal Chinelli alexandre Jose Vianna Barbosa de Araujo Carlos Alberto Pereira soares Graduate Program in Civil Engineering Fluminense Federal University Niterói Brazil

The environmental damage arising from the construction and engineering services was responsible for the appearance of several norms and resolutions regulating and directing the sector’s performance. In this article, we research how professionals with experience in public bids assess the difficulty degree of the implementation of those requirements and how they assess the environmental legislation regarding the protection and conservation of the environment, impact on costs, deadlines and the solution to environmental problems. The results show that industry professionals consider as “high” the level of difficulty to implement the addressed sustainability requirements, and that the Brazilian environmental legislation does not comply with its environmental protection role, increases the possibility of delays and costs of projects and services and hampers the emergence of solutions that could solve environmental problems.

关键词： Environmental Sustainability Requirements Environmental Protection Sustainable Procurement Construction and Engineering Services