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Journal of Civil Engineering and Architecture 2015年第12期9卷 1513-1522页

作者： alexandre H. Coelho Nataniel P. borges Jr. Nicolas P. borges Marcos D. Gallo Amir M. Valente Department of Civil Engineering Federal University of Santa Catarina (UFSC) Florianopolis SC 88040-970 Brazil Transportation and Logistics Laboratory (Lab Trans) Federal University of Santa Catarina (UFSC) Florianopolis SC 88040-970Brazil

Road geometric design data are a vital input for diverse transportation studies. This information is usually obtained from the road design project. However, these are not always available and the as-built course of the road may diverge considerably from its projected one, rendering subsequent studies inaccurate or impossible. Moreover, the systematic acquisition of this data for the entire road network of a country or even a state represents a very challenging and laborious task. This study＇s goal was the extraction of geometric design data for the paved segments of the Brazilian federal highway network, containing more than 47,000 km of highways. It presents the details of the method＇s adoption process, the particularities of its application to the dataset and the obtained geometric design information. Additionally, it provides a first overview of the Brazilian federal highway network composition （curves and tangents） and geometry.

关键词： Curve identification information extraction geometric design polygonal segmentation road.

Genetic diversity and structure of Drimys brasiliensis in southern Brazil:insights for conservation

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Journal of Forestry Research 2020年第4期31卷 1325-1332页

作者： alexandre Mariot Tiago Montagna Maurício Sedrez dos Reis Núcleo de Pesquisas Em Florestas Tropicais Pós-Graduacāo Em Recursos Genéticos VegetaisCentro de Ciências AgráriasUniversidade Federal de Santa CatarinaRodovia Admar Gonzaga1346FlorianópolisSC 88034-000Brazil

Population genetics studies are widely recognized for generating useful knowledge for biodiversity *** date,however,little is known about the levels and distribution of genetic diversity of Drymis brasiliensis(Miers LC),a tree species from the Atlantic ***,in this study,we investigated how genetic diversity is distributed within and among populations of *** from southern Brazil using allozyme markers to genotype reproductive trees(8 populations)and seedlings(3 populations).Furthermore,in two populations,we established two permanent plots(5.1 and 1 ha)to analyze fine-scale genetic structure(FSGS).Studied populations presented low levels of genetic diversity(reproductive=0.085;seedlings=0.054)and high fixation indexes(reproductive=0.396;seedlings=0.231).Genetic divergence among populations was equal to 0.05,which is significant,signaling that few populations can conserve large portions of the species total genetic *** was only detected for one population,when reproductive individuals were separated by less than40 *** genetic diversity combined with high fixation indexes clearly signal a risk of losing ***,conservation efforts should be aimed at enhancing gene flow within the studied populations.

关键词： Atlantic Rainforest Effective population size Fine-scale genetic structure Seed collection

N-methyl-D-aspartate receptor functions altered by neuronal PTP1B activation in Alzheimer’s disease and schizophrenia models

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Neural Regeneration Research 2022年第10期17卷 2208-2210页

作者： alexandre F.R.Stewart Hsiao-Huei Chen Department of Biochemistry Microbiology and ImmunologyUniversity of Ottawaand University of Ottawa Heart InstituteOttawaONCanada Centre for Infection Immunity and InflammationOttawaONCanada Medicine Cellular and Molecular MedicineUniversity of Ottawa Brain and Mind InstituteOttawa Hospital Research InstituteOttawaONCanada

Glutamate is the main exc i tatory neurotransmitter in the brain and binds to two major classes of receptors,theα-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid(AMPA)and the N-methyl-D-aspartate(NMDA)*** AMPA receptors that are immediately activated by glutamate release,NMDA receptors are blocked by magnesium and can only be activated by glutamate after membrane ***,NMDA receptors are only activated after repeated AMPA receptor activation by *** receptors are,for the most part,calcium-permeable *** influx through NMDA receptors modulates synaptic transmission in neurons based on prior history of excitation,and provides a means of scaling the strength of synapses required for Hebbian plasticity.

关键词： PTP1B aspartate NMDA

Holography,and the future of 3D display

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Light(Advanced Manufacturing) 2021年第4期2卷 31-44页

作者： Pierre-alexandre Blanche Wyant College of Optical Sciences University of ArizonaTucsonAZUSA

The pioneers of holography,Gabor,Leith,Upatnieks,and Denisyuk,predicted very early that the ultimate 3D display will be based on this *** conviction was rooted on the fact that holography is the only approach that can render all optical cues interpreted by the human visual *** 3D displays have been a dream chased after for many years,facing challenges on all fronts:computation,transmission,and *** numbers such as 6.6×10^(15) flops required for calculations,3×10^(15) b/s data rates,and 1.6×10^(12) phase pixels,the task has been *** article is reviewing the recent accomplishments made in the field of holographic 3D ***,the new developments in machine learning and neural network algorithms demonstrating that computer-generated holograms approach real-time processing.A section also discuss the problem of data transmission that can arguably be solved using clever compression algorithms and optical fiber transmission ***,we introduce the last obstacle to holographic 3D display,which is is the rendering ***,there is no further *** larger and faster spatial light modulators(SLMs),holographic projection systems are constantly *** pixel count on liquid crystal on silicon(LCoS)as well as microelectromechanical systems(MEMS)phase displays is increasing by the millions,and new photonic integrated circuit phased arrays are achieving real *** is only a matter of time for these systems to leave the laboratory and enter the consumer *** future of 3D displays is holographic,and it is happening now.

关键词： holographic rendering render

Comment on:local control and survival after induction chemotherapy and ablative radiation versus resection for pancreatic ductal adenocarcinoma with vascular involvement

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Hepatobiliary Surgery and Nutrition 2021年第5期10卷 672-674页

作者： Pauline Georges alexandre Doussot Department of Digestive Surgical Oncology-Liver Transplantation Unit CHU BesanconBesanconFrance

We read with interest the study from Jolissaint et *** issued in the Annals of Surgery(1).In this single center retrospective study,the authors compared oncological outcomes in patients with pancreatic ductal adenocarcinoma(PDAC)and vascular involvement who underwent pancreatectomy(n=105)*** dose ablative radiation(A-RT,n=104).All patients received induction chemotherapy first,over a recent study period[2014-2018].While the rationale for submitting patients to pancreatectomy or A-RT was not clearly stated in the Methods section,comparison between the two groups showed that patients allocated to A-RT were frailer with higher Charlson Comorbidity indexes and Eastern Cooperative Oncology Group(ECOG)scores and harbored significantly larger tumors,more often left-sided,with more arterial involvement as compared to patients in the pancreatectomy group.

关键词： involvement adenocarcinoma Surgery

National botanical gardens at the forefront of global plant conservation

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The Innovation 2023年第5期4卷 1-2页

作者： Hai Ren alexandre Antonelli South China Botanical Garden of the Chinese Academy of Sciences Guangzhou 510650China South China National Botanical Garden Guangzhou 510650China Royal Botanic Gardens KewRichmondLondonTW93AE SurreyUK Gothenburg Global Biodiversity Center Department of Biological and Environmental SciencesUniversity of GothenburgBox 46140530 GoteborgSweden|

Global changes in land use driven by demands on food,energy,and other resources in response to a rapidly increasing human population have collectively led to escalating environmental challenges,including biodiversity loss,global warming,environmental pollution,and ecosystem *** present,biodiversity is seriously threatened at global,regional,and local scales,which,in turn,threatens our own *** is a global asset of immense material and non-material value,providing us with food,medicine,building materials,fiber,and the ecological environment required for our well-being and health.

关键词： collective pollution seriously

Postoperative pancreatic fistula after distal pancreatectomy: pancreatic thickness and duct size as the only denominators?

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Hepatobiliary Surgery and Nutrition 2023年第2期12卷 229-231页

作者： Antoine Notte alexandre Doussot Department of Digestive Surgical Oncology Liver Transplantation UnitChu BesanconFrance

We read with great interest the multicenter study from De Pastena and colleagues dealing with the prediction of clinically relevant postoperative pancreatic fistula(CR-POPF)after distal pancreatectomy(DP)(1).The study aimed to develop two *** was solely based on preoperative *** second one relied on both preoperative and intraoperative data.

关键词： fistula dealing distal

Nucleon Finite Volume Effect and Nuclear Matter Properties in a Relativistic Mean-Field Theory

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Communications in Theoretical Physics 2006年第6X期46卷 1052-1058页

作者： R. Costa A.J. Santiago H. Rodrigues J. Sa borges Instituto de Fisica Universidade do Estado do Rio de Janeiro Rio de Janeiro-RJ 20559-900 Brazil Centro Federal de Educ~ao Tecnológica Rio de Janeiro Brazil

Effects of excluded volume of nucleons on nuclear matter are studied, and the nuclear properties that follow from different relativistic mean-field model parametrizations are compared. We show that, for all tested parametrizations, the resulting volume energy al and the symmetry energy J are around the acceptable values of 16 MeV and 30 MeV, and the density symmetry L is around 100 MeV. On the other hand, models that consider only linear terms lead to incompressibility Ko much higher than expected. For most parameter sets there exists a critical point （pc, δc）, where the minimum and the maximum of the equation of state are coincident and the incompressibility equals zero. This critical point depends on the excluded volume parameter r. If this parameter is larger than 0.5 fm, there is no critical point and the pure neutron matter is predicted to be bound. The maximum value for neutron star mass is 1.85M⊙, which is in agreement with the mass of the heaviest observed neutron star 4U0900-40 and corresponds to r = 0.72 fm. We also show that the light neutron star mass （1.2M⊙） is obtained for r ≌ 0.9 fro.

关键词： nuclear matter relativistic models nuclear matter aspects of neutron stars

Limit behaviour of the minimal solution of a BSDE with singular terminal condition in the non Markovian setting

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Probability, Uncertainty and Quantitative Risk 2020年第1期5卷 1-24页

作者： Dmytro Marushkevych alexandre Popier Laboratoire Manceaude Mathematiques Le Mans UniversiteAvenue Olivier Messiaen72085 Le Mans cedex 9France

We use the functional Ito calculus to prove that the solution of a BSDE with singular terminal condition verifies at the terminal time:lim inf_(t→T)Y(t)=ξ=Y(T).Hence,we extend known results for a non-Markovian termi... 详细信息

关键词： Backward stochastic differential equations Functional stochastic calculus Singularity

Liver transplantation for perihilar cholangiocarcinoma is not a provocative idea

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Hepatobiliary Surgery and Nutrition 2023年第2期12卷 232-234页

作者： alexandre Chebaro Heithem Jeddou Service de Chirurgie Hépatobiliaire et Digestive CHU RennesUniv RennesRennesFrance Inserm EHESPIrset(Institut de recherche en santéenvironnement et travail)-UMR_S 1085Univ RennesRennesFrance

This is a multicenter benchmarking study on liver transplantation(LT)for perihilar cholangiocarcinoma(PHC)after neoadjuvant chemoradiotherapy(1).The study comprises of 134 patients from 2014 to 2018 among whom the majority had underlying primary sclerosing cholangitis(PSC).Dropout rate was available from 4 out of 17 centers and was 28%,primarily for oncological reasons(tumor progression and lymph node invasion).All patients followed neo-adjuvant chemoradiotherapy according to the Mayo(88%)or Mayo-like *** grafts originated from brain-dead donors in 61.3%of cases and from living donors in 29.7%of cases.

关键词： Liver invasion patients