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X-Ray and VUV Spectra from the Laser Plasma Produced with “Kanal-2” Facility

Journal of Modern Physics 2014年第2期5卷 92-97页

作者： Andrey Aleksandrovich Kologrivov Mikhail Vladimirovich Osipov Victor nikolaevich Puzyrev alexandr nikolaevich Starodub Oleg Feliksovich Yakushev P. n. Lebedev Physical Institute of RAS Moscow Russia

The paper presents experimental results obtained on “Kanal-2” facility. Laser radiation focusing on the surface of plane magnesium targets created the high temperature plasma, which emitted X-ray and vacuum ultraviolet (VUV) radiation. This radiation spectrum was investigated with two spectrographs: the mica crystal spectrograph (working range 8.2 ? - 9.6 ?) and the grazing incidence VUV spectrograph (working rage 30 ? - 130 ?). A set of beryllium stepwise attenuators appended the diagnostic complex and allowed us to get an approximated picture of a continuous spectrum within the range of 2.2 ? - 6.2 ?. The estimation of the plasma electron temperature Te from the ratio between the intensity of the dielectronic satellites and the resonance line gives Te ~ 180 eV. The ratio between the intensity of the resonance and intercombination lines gives the electron density of the emitting zone ne ~ 2 × 1019 cm-3. Some lines observed within the spectral range of 8.5 ? - 9.1 ? belong to none of the transitions of Mg ions. Perhaps the observed spectrum is determined by the transitions in so-called hollow ions of Mg, i.e. in the ions with unfilled inner shells. The spectra obtained with the grazing incidence spectrograph and with the minimum-directioned discrepancy iteration method of spectrum reconstruction from the attenuation curve in the beryllium stepwise attenuators are also presented.

关键词： Laser Plasma X-Ray Spectra VUV Spectra Plasma Diagnostics

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DETERMInATIOn OF LIMITInG AMOUnT OF ABSEnT TEnDOnS In PRESTRESSED nUCLEAR POWER PLAnT COnTAInMEnT

DETERMINATION OF LIMITING AMOUNT OF ABSENT TENDONS IN PRESTR...

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第十八届国际反应堆结构力学大会

作者： Victor n.Medvedev alexandr S.Kiselev Alexey S.Kiselev Valery F.Strizhov Alexey A.Lopanchuk Sergey S.nefedov nuclear Safety Institute（IBRAE） Russian Academy of Sciences nuclear Safety Institute（IBRAE） Russian Academy of Sciences nuclear Safety Institute（IBRAE） Russian Academy of Sciences nuclear Safety Institute（IBRAE） Russian Academy of Sciences Rosenergoatom Company Design Branch Rosenergoatom Company Design Branch

＜正＞ Prestressed reinforced-concrete containment of nuclear Power Plants（nPPs）with VVER-1000 consists of a cylinder part and a flat dome, the inner radius of cylinder making up 22.5 m, the design width of cylinder wall～1.2 m and that of the dome～1.1 m. The cylinder part and the dome part of containment are prestressed by tendons. Tendons of the cylinder part are arranged helicoidally, tendons of the dome part are installed orthogonally. Reinforcing die-rolled section rods（class A-Ⅲ） are located close to the outer and inner wall surface of containment. There were real situations of spontaneous destruction of tendons

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Resistance of breast cancer cells to paclitaxel is associated with low expressions of miRnA-186 and miRnA-7

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Cancer Drug Resistance 2023年第3期6卷 596-610页

作者： Vera Apollonova Daniil Plevako alexandr Garanin Elena Sidina Lidia Zabegina Margarita Knyazeva Viktoria Smirnova Anna Artemyeva Petr Krivorotko Anastasia Malek Breast Surgical Oncology N.N.Petrov National Medical Research Center of OncologySt.Petersburg 197758Russia Subcellular Technology Lab N.N.Petrov National Medical Research Center of OncologySt.Petersburg 197758Russia Department of Pathology N.N.Petrov National Medical Research Center of OncologySt.Petersburg 197758Russia

Aim:neo-adjuvant chemotherapy is a common approach for the complex treatment of breast cancer(BC)and paclitaxel(PTX)is frequently included in the therapeutic ***,the effect of PTX-based treatment is hard to predict precisely based on routinely used *** microRnAs are considered a new promising class of biomarkers,the link between miRnA expression and PTX resistance of BC cells needs to be well *** study aimed at the identification of miRnAs associated with responses of BC cells to ***:Intrinsic PTX sensitivity and miRnA profiling were assayed in five BC cell lines to identify candidate *** miRnA(n.15)expressions were analyzed by real-time-quantitative polymerase chain reaction(RT-qPCR)in BC tissue samples(n.31)obtained from a diagnostic *** were analyzed in the context of the effect of two cycles of PTX and the effect of the completed scheme of neoadjuvant *** study’s design facilitated the evaluation of the effect of PTX on cells and the identification of features of the microRnA expression profiles associated exclusively with sensitivity to this ***:miR-186 and miR-7 expression in BC tissues was higher in patients with better outcomes of PTX-based neoadjuvant ***:High expressions of miR-186 and miR-7 are associated with good response to PTX,whereas their low expressions may be associated with resistance to PTX in BC,indicating the possibility of developing innovative test systems for the prediction of the PTX response,which can be used before the start of neo-adjuvant chemotherapy for BC.

关键词： Breast cancer paclitaxel resistance neoadjuvant therapy miRnA miR-186 miR-7

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Observation of a single protein by ultrafast X-ray diffraction

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Light(Science & Applications) 2024年第1期13卷 80-90页

作者： Tomas Ekeberg Dameli Assalauova Johan Bielecki Rebecca Boll Benedikt J.Daurer Lutz A.Eichacker Linda E.Franken Davide E.Galli Luca Gelisio Lars Gumprecht Laura H.Gunn Janos Hajdu Robert Hartmann Dirk Hasse alexandr Ignatenko Jayanath Koliyadu Olena Kulyk Ruslan Kurta Markus Kuster Wolfgang Lugmayr Jannik Lübke Adrian P.Mancuso Tommaso Mazza Carl nettelblad Yevheniy Ovcharenko Daniel E.Rivas Max Rose Amit K.Samanta Philipp Schmidt Egor Sobolev nicusor Timneanu Sergey Usenko Daniel Westphal Tamme Wollweber Lena Worbs Paul Lourdu Xavier Hazem Yousef Kartik Ayyer Henry n.Chapman Jonas A.Sellberg Carolin Seuring Ivan A.Vartanyants Jochen Küpper Michael Meyer Filipe R.n.C.Maia Laboratory of Molecular Biophysics Department of Cell and Molecular BiologyUppsala UniversityHusargatan 3(Box 596)SE-75124 UppsalaSweden Deutsches Electronen-Synchrotron DESY Notkestrasse 8522607 HamburgGermany European XFEL Holzkoppel 422869 SchenefeldGermany Diamond Light Source Harwell Science&Innovation CampusDidcot OX110DEUK University of Stavanger Centre Organelle ResearchRichard-Johnsensgate 44021 StavangerNorway Leibniz Institute for Experimental Virology(HPI) Centre for Structural Systems BiologyNotkestraße 8522607 HamburgGermany Dipartimento di Fisica“Aldo Pontremoli” Universitàdegli Studi di Milanovia Celoria 1620133 MilanoItaly Center for Free-Electron Laser Science DESY22607 HamburgGermany Plant Biology Section School of Integrative Plant ScienceCornell UniversityIthacaNY 14853USA PnSensor GmbH Otto-Hahn-Ring 6D-81739 MünchenGermany Biomedical and X-Ray Physics Department of Applied PhysicsAlbaNova University CenterKTH Royal Institute of TechnologySE-10691 StockholmSweden ELI Beamlines/IoP Institute of Physics AS CR v.v.i.Na Slovance 218221 Prague 8Czech Republic Multi-User CryoEM Facility Centre for Structural Systems BiologyNotkestr.8522607 HamburgGermany University Medical Center Hamburg-Eppendorf(UKE) Martinistrasse 5220246 HamburgGermany The Hamburg Center for Ultrafast Imaging Universität HamburgLuruper Chaussee 14922761 HamburgGermany Department of Physics Universität HamburgLuruper Chaussee 14922761 HamburgGermany Department of Chemistry and Physics La Trobe Institute for Molecular ScienceLa Trobe UniversityMelbourneVIC 3086Australia Division of Scientific Computing Science for Life LaboratoryDepartment of Information TechnologyUppsala UniversityBox 337SE-75105 UppsalaSweden European Molecular Biology Laboratory c/o DESYNotkestrasse 8522607 HamburgGermany Department of Physics and Astronomy Uppsala UniversityBox 516SE-75120 UppsalaSweden Max Planck Institute for the Structure and Dynamics of Matter Luruper Chaussee 14922761 HamburgGe

The idea of using ultrashort X-ray pulses to obtain images of single proteins frozen in time has fascinated and inspired *** was one of the arguments for building X-ray free-electron *** to theory,the extremely intense pulses provide sufficient signal to dispense with using crystals as an amplifier,and the ultrashort pulse duration permits capturing the diffraction data before the sample inevitably *** was first demonstrated on biological samples a decade ago on the giant *** then,a large collaboration has been pushing the limit of the smallest sample that can be *** ability to capture snapshots on the timescale of atomic vibrations,while keeping the sample at room temperature,may allow probing the entire conformational phase space of *** we show the first observation of an X-ray diffraction pattern from a single protein,that of Escherichia coli GroEL which at 14 nm in diameter is the smallest biological sample ever imaged by X-rays,and demonstrate that the concept of diffraction before destruction extends to single *** the pattern,it is possible to determine the approximate orientation of the *** experiment demonstrates the feasibility of ultrafast imaging of single proteins,opening the way to single-molecule time-resolved studies on the femtosecond timescale.

关键词： smallest intense ultrafast

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功能化纤维对氨气的循环吸附再生性能研究

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环境污染与防治 2023年第11期45卷 1523-1526,1532页

作者：黄做华田振邦黄伟庆李龙赵亮段文杰 alexandr Bildyukevich 王俊李宾宾河南省科学院化学研究所有限公司河南郑州450002 白俄罗斯国家科学院物理有机化学研究所白俄罗斯明斯克220072

采用吸附容量、交换容量、断裂强力、扫描电镜、红外光谱表征功能化纤维(RPFC-Ⅰ纤维),并系统考察RPFC-Ⅰ纤维的理化特性及其对氨气的循环吸附再生性能。结果表明,RPFC-Ⅰ纤维对氨气具有良好的循环吸附再生性能且内部分子结构非常稳定... 详细信息

采用吸附容量、交换容量、断裂强力、扫描电镜、红外光谱表征功能化纤维(RPFC-Ⅰ纤维),并系统考察RPFC-Ⅰ纤维的理化特性及其对氨气的循环吸附再生性能。结果表明,RPFC-Ⅰ纤维对氨气具有良好的循环吸附再生性能且内部分子结构非常稳定。在循环吸附再生21次过程中,RPFC-Ⅰ纤维对氨气的吸附容量为90.2~96.3 mg/g、交换容量为6.75~6.90 mmol/g、断裂强力为0.053~0.063 n,均未发生明显变化。RPFC-Ⅰ纤维具有吸附容量高、耐酸腐蚀性好、净化性能稳定、材料再生条件温和、可循环再生使用等优点,未来市场应用前景广阔。

关键词：功能化纤维 RPFC-Ⅰ纤维氨气循环吸附再生性能

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