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通过镍(Ⅱ)-硫键和碘离子基元反应有理合成碘-二硫醇盐桥联的双核镍-镍配合物(英文)

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武汉科技学院学报 2008年第8期21卷 70-77页

作者：王强安德鲁.马朱文锋亚力山大.布雷克克莱尔.威尔森斯蒂芬.戴维斯马丁.施罗德诺丁汉大学化学学院武汉科技学院环境科学研究所湖北武汉430073

本文报道由于碘离子对不稳定的Ni(Ⅱ)-s(芳基硫醇盐)键的亲核作用,使得Fe(CO)4I2和Ni(sR)2(dppe(sR=芳基硫醇盐)之间的反应生成NiI2(dppe)。含碘和二芳基硫醇盐离子桥联的Ni-Ni双核配合物[(dppe)Ni(μ-I)(μ-pdt)Ni(dppe)]I和[(dppe)Ni(μ-I)(μ-edt)Ni(dppe)]I可方便地由[NiI2(dppe)]和[Ni(pdt)(dppe)]或[Ni(edt)(dppe)]在二氯甲烷的溶液中的反应制得;该类反应可认为是由于硫醇盐离子基团中s-供体上的孤对电子对Ni-I键的进攻所致。另一方面,我们观察到[FeCp(CO)2I]和[Ni(pdt)(dppe)]或[Ni(edt)(dppe)]在二氯甲烷中的反应极其缓慢;但当向上述反应体系中加入NH4PF6进行复分解置换后,源于碘离子和Ni(Ⅱ)-s键的作用同样可得到含碘与二芳基硫醇盐离子桥联的Ni-Ni双核配合物[(dppe)Ni(μ-I)(μ-pdt)Ni(dppe)]PF6和[(dppe)Ni(μ-I)(μ-edt)Ni(dppe)]PF6。实验结果说明在本文所讨认的镍(Ⅱ)-硫醇盐离子-膦配合物中,Ni(Ⅱ)-s键的反应活性随桥联的第二金属离子和不同的碘离子基元而改变。

关键词：镍,硫醇盐双核配合物镍-硫醇盐-碘配合物

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Accretion in strong field gravity with eXTP

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science China(Physics,Mechanics & Astronomy) 2019年第2期62卷 45-73页

作者： Alessandra De Rosa Phil Uttley LiJun Gou Yuan Liu Cosimo Bambi Didier Barret Tomaso Belloni Emanuele Berti stefano Bianchi Ilaria Caiazzo Piergiorgio Casella Marco Feroci Valeria Ferrari Leonardo Gualtieri Jeremy Heyl Adam Ingram Vladimir Karas FangJun Lu Bin Luo Giorgio Matt sara Motta Joseph Neilsen Paolo Pani Andrea santangelo XinWen shu JunFeng Wang Jian-Min Wang YongQuan Xue YuPeng Xu WeiMin Yuan YeFei Yuan shuang-Nan Zhang shu Zhang Ivan Agudo Lorenzo Amati Nils Andersson Cristina Baglio Pavel Bakala Altan Baykal sudip Bhattacharyya Ignazio Bombaci NiccolóBucciantini Fiamma Capitanio Riccardo Ciolfi Wei K.Cui Filippo D'Ammando Thomas Dauser Melania Del santo Barbara De Marco Tiziana Di salvo Chris Done Michal Dovciak Andrew C.Fabian Maurizio Falanga Angelo Francesco Gambino Bruce Gendre Victoria Grinberg alexander Heger Jeroen Homan Rosario Iaria JiaChen Jiang ChiChuan Jin Elmar Koerding Manu Linares Zhu Liu Thomas J.Maccarone Julien Malzac Antonios Manousakis Frédéric Marin Andea Marinucci Missagh Mehdipour Mariano Méndez simone Migliari Cole Miller Giovanni Miniutti Emanuele Nardini Paul T.O'Brien Julian P.Osborne Pierre Olivier Petrucci Andrea Possenti Alessandro Riggio Jerome Rodriguez Andrea sanna LiJing shao Malgosia sobolewska Eva sramkova Abigail L.stevens Holger stiele Giulia stratta Zdenek stuchlik Jiri svoboda Fabrizio Tamburini Thomas M.Tauris Francesco Tombesi Gabriel Torok Martin Urbanec Frederic Vincent QingWen Wu Feng Yuan Jean J.M.in't Zand Andrzej A.Zdziarski XinLin Zhou INAF-Istituto di Astrofisica e Planetologie spaziali Via Fosso del Cavaliere Anton Pannekoek Institute for Astronomy University of Amsterdam National Astronomical Observatories Chinese Academy of Science Institute of High Energy Physics Chinese Academy of Science Center for Field Theory and Particle Physics and Department of Physics Fudan University IRAP Universitéde ToulouseCNRSUPSCNES INAF-Osservatorio Astronomico di Brera Department of Physics and Astronomy The University of MississippiUniversity Dipartimento di Matematica e Fisica Universitàdegli studi Roma Tre University of British Columbia INAF-Osservatorio Astronomico di Roma INFN-Roma 2 c/o Dipartimento di Fisica II Universit?di Roma"Tor Vergata" Dipartimento di Fisica Universitàdegli Studi di Roma"La Sapienza"&Sezione INFN Roma1 Department of Physics University of OxfordClarendon Laboratory Astronomical Institute Academy of Sciences school of Astronomy and space science Nanjing University MIT Kavli Institute for Astrophysics and space Research Institut für Astronomie und Astrophysik Eberhard Karls Universität Department of Physics Anhui Normal University Department of Astronomy and Institute of Theoretical Physics and Astrophysics Xiamen University CAs Key Laboratory for Research in Galaxies and Cosmology Department of AstronomyUniversity of Science and Technology of China Instituto de Astrofísica de Andalucia(CsIC) Glorieta de la Astronomía s/n INAF-Istituto di Astrofisica spaziale e Fisica cosmica di Bologna Mathematical sciences and sTAG Research Centre University of Southampton New York University Abu Dhabi Institute of Physics and Research Centre for Computational Physics and Data Processing Faculty of Philosophy&ScienceSilesian University in OpavaíBezru?ovo nám. Department of Physics Middle East Technical University Department of Astronomy and Astrophysics Tata Institute of Fundamental Research Dipartimento di Fisica Universit?di Pisa&INFN INAF-Osservatorio Astrofisico di Arcetri INAF-Osservatorio Astronomico di Padova INFN-TIFPA Trento Ins

In this paper we describe the potential of the enhanced X-ray Timing and Polarimetry(eXTP) mission for studies related to accretion flows in the strong field gravity regime around both stellar-mass and supermassive black-holes. eXTP has the unique capability of using advanced "spectral-timing-polarimetry" techniques to analyze the rapid variations with three orthogonal diagnostics of the flow and its geometry, yielding unprecedented insight into the inner accreting regions, the effects of strong field gravity on the material within them and the powerful outflows which are driven by the accretion process.

关键词： X-ray black holes physics accretion

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search for the doubly heavy baryons Ω^(0)_(bc) and E^(0)_(bc) decaying to Λ^(+)_(c)π^(-) and E^(+)_(c)π^(-)

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Chinese Physics C 2021年第9期45卷 10-21页

作者： R.Aaij C.Abelian Beteta T.Ackernley B.Adeva M.Adinolfi H.Afshamia C.A.Aidala s.Aiola Z.Ajaltouni s.Aka J.Albrecht F.Alessio M.alexander A.Alfonso Albero Z.Aliouche G.Alkhazov P.Alvarez Cartelie s.Amato Y.Amhis L.An L.Anderlini A.Andreianov M.Andreotti F.Archilli A.Artamonov M.Artuso K.Arzymatov E.Aslanides M.Atzeni B.Audurier s.Bachmann M.Bachmayer J.J.Back P.Baladron Rodriguez V.Balagura W.Baldini J.Baptista Leite R.J.Barlow s.Barsuk W.Barter M.Bartolini F.Baryshnikov J.M.Basels G.Bassi B.Batsukh A.Battig A.Bay M.Becker F.Bedeschi I.Bediaga A.Beiter V.Belavin s.Belin V.Bellee K.Belous I.Belov I.Belyaev G.Bencivenni E.Ben-Haim A.Berezhnoy *** D.Beminghoff H.C.Bernstein C.Bertella A.Bertolin C.Betancourt F.Betti Ia.Bezshyiko s.Bhasin J.Bhom L.Bian M.s.Bieker s.Bifani P.Billoir M.Birch F.C.R.Bishop A.Bitadze A.Bizzeti M.Bjorn M.P.Blago T.Blake F.Blanc s.Blusk D.Bobulska J.A.Boelhauve O.Boente Garcia T.Boettcher A.Boldyrev A.Bondar N.Bondar s.Borghi M.Borisyak M.Borsato J.T.Borsuk s.A.Bouchiba T.J.V.Bowcock A.Boyer C.Bozzi M J.Bradley s.Braun A.Brea Rodriguez M.Brodski J.Brodzicka A.Brossa Gonzalo D.Brundu A.Buonaura C.Burr A.Bursche A.Butkevich J.s.Butter J.Buytaert W.Byczynski s.Cadeddu H.Cai R.Calabrese L.Calefice L.Calero Diaz s.Cali R.Calladine M.Calvi M.Calvo Gomez P.Camargo Magalhaes A.Camboni P.Campana A.F.Campoverde Quezada s.Capelli L.Capriotti A.Carbone G.Carboni R.Cardinale A.Cardini I.Carli P.Camiti L.Carus K.Carvalho Akiba A.Casais Vidal G.Casse M.Cattaneo G.Cavallero s.Celani J.Cerasoli A.J.Chadwick M.G.Chapman M.Charles Ph.Charpentier G.Chatzikonstantinidis C.A.Chavez Barajas M.Chefdeville C.Chen s.Chen A.Chernov V.Chobanova s.Cholak M.Chrzaszcz A.Chubykin V.Chulikov P.Ciambrone M.F.Cicala X.Cid Vidal G.Ciezarek P.E.L.Clarke M.Clemencic H.V.Cliff J.Closier J.L.Cobbledick V.Coco J.A.B.Coelho J.Cogan E.Cogneras L.Cojocariu P.Collins T.Colombo L.Congedo A.Contu N.Cooke G.Coombs G.Corti C.M.Costa sobral B.Couturier D.C.Craik J.Crkovska M.Cruz Torres R.Currie C.L.Da silva E.Dall'Occo J.Dalseno C.D'Ambrosi Centro Brasileiro de Pesquisas Fisicas(CBPF) Rio de JaneiroBrazil Universidade Federal do Rio de Janeiro(UFRJ) Rio de JaneiroBrazil Center for High Energy Physics Tsinghua UniversityBeijingChina Institute of High Energy Physics(IHEP) BeijingChina school of Physics state Key Laboratory of Nuclear Physics and Technology Peking UniversityBeijingChina University ofChinese Academy of sciences BeijingChina Institute of Particle Physics Central China Normal UniversityWuhanHubeiChina Univ.savoie Mont Blanc CNRSIN2P3-LAPPAnnecyFrance Universite Clermont Auvergne CNRS/IN2P3LPCClermont-FerrandFrance Aix Marseille Univ CNRS/IN2P3CPPMMarseilleFrance Universite Paris-saclay CNRS/IN2P3IJCLabOrsayFrance Laboratoire Leprince-Ringuet CNRS/IN2P3Ecole PolytechniqueInstitut Polytechnique de ParisPalaiseauFrance LPNHE Sorbonne UniversiteParis Diderot Sorbonne Paris CiteCNRS/FN2P3ParisFrance I.Physikalisches Institut RWTH Aachen UniversityAachenGermany Fakultat Physik Technische Universitat DortmundDortmundGermany Max-Planck-Institut für Kemphysik(MPIK) HeidelbergGermany Physikalisches Institut Ruprecht-Karls-Universitat HeidelbergHeidelbergGermany school of Physics University College DublinDublinIreland INFN sezione di Bari BariItaly INFN sezione di Bologna BolognaItaly INFN sezione di Ferrara FerraraItaly INFN sezione di Firenze FirenzeItaly INFN Laboratori Nazionali di Frascati FrascatiItaly INFN sezione di Genova GenovaItaly INFN sezione di Milano MilanoItaly INFN sezione di Milano-Bicocca MilanoItaly INFN sezione di Cagliari MonserratoItaly Universita degli studi di Padova Universita e INFNPadovaPadovaItaly INFN sezione di Pisa PisaItaly INFN sezione di Roma La sapienza RomaItaly INFN sezione di Roma Tor Vergata RomaItaly Nikhef National Institute for subatomic Physics AmsterdamNetherlands Nikhef National Institute for subatomic Physics and VU University Amsterdam AmsterdamNetherlands AGH-University of science and Technology Faculty of Physics and Applied Computer ScienceKr

The first search for the doubly heavyΩ^(0)_(bc)baryon and a search for the E^(0)_(bc)baryon are performed using pp collision data collected via the LHCb experiment from 2016 to 2018 at a centre-of-mass energy of 13 TeV,corresponding to an integrated luminosity of 5.2 fb^(-1).The baryons are reconstructed via their decays to Λ^(+)_(c)π^(-)and E^(+)_(c)π^(-).No significant excess is fbund for invariant masses between 6700 and 7300 MeV/c^(2),in a rapidity range from 2.0 to 4.5 and a transverse momentum range from 2 to 20 MeV/*** limits are set on the ratio of the Ω^(0)_(bc)and E^(0)_(bc)production cross-section times the branching fraction to Λ^(+)_(c)π^(-)(E^(+)_(c)π^(-))relative to that of the Λ^(0)_(b)(E^(0)_(b))baryon,for different lifetime hypotheses,at 95%confidence *** upper limits range from 0.5 x 10^(-4)to 2.5 x 10^(-4)for theΩ^(0)_(bc)→Λ^(+)_(c)π^(-)(E^(0)_(bc)→Λ^(+)_(c)π^(-))decay,and from 1.4x 10^(-3)to 6.9 x 10^(-3)for theΩ^(0)_(bc)→E^(+)_(c)π^(-)(E^(0)_(bc)→E^(+)_(c)π^(-))decay,depending on the considered mass and lifetime of theΩ^(0)_(bc)(E^(0)_(bc))baryon.

关键词： B physics quarkonium spectroscopy heavy quark production

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结肠直肠癌姑息治疗的改进

德国医学 2001年第4期18卷 220-221页

作者： A.Wein C.Riedel B.Hanke s.Lampert W.Brückl B.Reingruber W.Hohenberger E.G.Hahn 张林 MedizinischeKlinik I mit Poliklinik Friedrich-Alexander-Universitat Erlangen-NumbergKrankenhausstrabe 12D-91054 ErlangenGermany MedizinischeKlinik I mit Poliklinik Friedrich-Alexander-Universitat Erlangen-Numberg 华中科技大学同济医学院附属同济医院

结肠直肠癌的发病率约为50/100?000,占女性肿瘤的第二位和男性肿瘤的第三位.约20?000例病人可以形成同时或异时的转移,最常见为肝转移.这类病人是行转移灶切除术的绝对适应证,因为根治手术的5年生存率可以达到25%～38%.如果不能切除的话... 详细信息

结肠直肠癌的发病率约为50/100?000,占女性肿瘤的第二位和男性肿瘤的第三位.约20?000例病人可以形成同时或异时的转移,最常见为肝转移.这类病人是行转移灶切除术的绝对适应证,因为根治手术的5年生存率可以达到25%～38%.如果不能切除的话,应该进行其他的姑息治疗,本文对此综述如下.

关键词：结肠直肠癌外科切除术治疗方法药物治疗化疗

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不同方法获得的脂肪来源干细胞再生能力比较：超声辅助吸脂与传统脂肪抽吸对比

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中国美容整形外科杂志 2015年第8期26卷 J0011-J0011页

作者： David Atashroo Dominik Duscher Zeshaan N. Maan Elizabeth R. Zielins Kevin Paik alexander Whittam Michelle Lin Adrian McArdle Christopher Duldulao t Graham G. Walmsley Michael s.Hu Ruth Tevlin Derrick C. Wan Geoffrey C. Gurtner Michael T. Longaker 朱利娜高景恒张晨袁继龙不详《中国美容整形外科杂志》编辑部大连大学附属新华医院整形外科辽宁省人民医院整形外科

背景与目的超声辅助吸脂（ultrasound assisted liposuction，UAL）因其获取脂肪容易，且可让创伤和失血最小化，受到整形外科医师的青睐。但是，很少有研究报道这种方法获取的脂肪来源干细胞（adipose derived stromal cells，ADsCs）... 详细信息

背景与目的超声辅助吸脂（ultrasound assisted liposuction，UAL）因其获取脂肪容易，且可让创伤和失血最小化，受到整形外科医师的青睐。但是，很少有研究报道这种方法获取的脂肪来源干细胞（adipose derived stromal cells，ADsCs）的质量。ADsCs在基于细胞的治疗方法中的作用也在急剧增长。因此，本研究比较了传统脂肪抽吸（suctionassistedliposuction，sAL）方法获得的ADsCs与UAL方法获得的ADsCs之间再生能力的差异。方法分别采用sAL和UAL方法，从健康人中获取脂肪并培养ADsCs；采用荧光辅助细胞分选（fluorescent assisted cell sorting，FACs）方法，分析ADsCs的产量。利用MTT比色法分析ADsCs的增殖能力，并在培养基中进行成脂和成骨分化诱导。将基因表达谱与qPCR进行对比。利用细胞染色比较成脂和成骨分化标记物。建立小鼠创伤愈合模型，在水凝胶支架上，分别播种采用sAL方法获取的ADsCs（sAL组）和采用UAL方法获取的ADsCs（UAL组），水凝胶组只加入水凝胶作为对照，同时比较3组的组织再生能力。结果UAL与sAL方法获得的ADsCs相比，在细胞数量和增殖能力方面的差异无统计学意义。油红O染色显示两者成脂分化能力没有差异，分化7d时，PPAR-γ受体和LPL的表达差异无统计学意义也证实了这一点（P〉0．05）。同样，碱性磷酸酶和茜素红染色也显示了两者相似的成骨分化能力，而且成骨标志物Runx-2、骨桥蛋白和骨钙蛋白的表达差异也无统计学意义（P〉0．05）。sAL组和UAL组的愈合速度明显大于水凝胶组（P〈0．05），sAL和UAL两组之间差异无统计学意义（P〉0．05）。结论与传统sAL方法相比，UAL方法可获得相等增殖能力的ADsCs，并用于以细胞疗法为基础的治疗。

关键词：细胞再生能力脂肪抽吸吸脂超声 ADsCs 脂肪来源干细胞成骨分化整形外科医师

Methane Concentration Influence on Combustion in a Rapid Compression Machine under DFICE Relevant Conditions

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Journal of Mechanics Engineering and Automation 2023年第2期13卷 40-53页

作者： R.Clemente-Mallada A.Peter s.Riess L.strauss H.Fajri M.Wensing Fluid systems Engineering Friedrich-Alexander UniversityCauerstrasse 4Erlangen-Tennenlohe 91058Germany

In this experimental work,an optically accessible rapid compression machine is used to study the ignition and combustion process under engine relevant operation conditions for five different air-natural gas equivalence ratios(λ)ignited with either 12.2 mg or 6.7 mg of pilot diesel injected at 1,600 *** temperature of the ambient mixture,walls and injector was 333 ***,for the short(6.7 mg)diesel injection,the variation in the ID(ignition delay)for two higher ambient temperatures(343 K and 353 K)was *** and piston displacement are recorded while two high-speed cameras simultaneously capture signals in the visible range spectrum and at 305 nm wavelength for OH^(*)chemiluminescence *** is measured both from OH^(*)and pressure *** the recorded data,the heat release ratio is estimated and compared with the visual *** gives an insight of the temporal and spatial evolution of the flame,as well as a qualitative perception of the transition from spray ignition into a premixed flame in the ambient fuel-air *** was found that increasing the methane concertation delays the ignition,reduces the natural flame luminosity and enhances the OH^(*)chemiluminescence signal.

关键词： Dual-fuel natural gas diesel rapid compression machine ID.

人类修复相关雪旺细胞在体具有抗原呈递细胞的功能

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神经损伤与功能重建 2022年第11期17卷 682-682页

作者： Jakob Berner Tamara Weiss Helena sorger Fikret Rifatbegovic Max Kauer Reinhard Windhager alexander Dohnal Peter F Ambros Inge MAmbros Kaan Boztug Peter steinberger sabine Taschner-Mandl 杜一星(编译) st.Anna Children's Cancer Research Institute(CCRI) ViennaAustria st.Anna Children's Hospital ViennaAustria Department of Plastic Reconstructive and Aesthetic SurgeryMedical University of Vienna Department of Orthopedics and Trauma surgery Medical University of ViennaViennaAustria Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases(LBI-RUD) ViennaAustria Center for Molecular Medicine(CeMM) ViennaAustria. Institute of Immunology Medical University of ViennaViennaAustria 不详

雪旺细胞(sCs)的可塑性潜能因其在神经损伤后和周围神经系统疾病中发挥作用而备受关注。有关免疫细胞和雪旺细胞之间相互作用的研究表明雪旺细胞参与炎症过程。然而,人类雪旺细胞的免疫能力主要是从神经病变中推断出来的,但神经损伤后... 详细信息

雪旺细胞(sCs)的可塑性潜能因其在神经损伤后和周围神经系统疾病中发挥作用而备受关注。有关免疫细胞和雪旺细胞之间相互作用的研究表明雪旺细胞参与炎症过程。然而,人类雪旺细胞的免疫能力主要是从神经病变中推断出来的,但神经损伤后雪旺细胞是否直接调节适应性免疫反应尚不清楚。本研究对人类修复相关雪旺细胞(hrsCs)的免疫调节能力进行综合分析,hrsCs概括了雪旺细胞对体外神经损伤的反应。我们使用有效的人类周围神经原代hrsCs培养模型,分析了转录组、分泌组、以及细胞表面与先天免疫和适应性免疫相关的通路和标志物相关的蛋白;进行了吞噬作用测定,并监测了同种异体共培养细胞中的T细胞亚群激活。本研究结果表明hrsC具有吞噬作用,这与MHCⅡ的高表达一致。此外,hrsC表达协同调节蛋白,如CD40、CD80、B7H3、CD58、CD86和HVEM,释放过多的趋化因子、基质重塑蛋白、促炎及抗炎细胞因子,并在IFNγ进行促炎刺激后上调T细胞对PD-L1分子的抑制。与单核细胞相反,单独的hrsC不足以触发同种异体CD4+和CD8+T细胞,但会限制外源激活的T细胞的数量和激活状态。本研究表明,hrsCs具有体外专职抗原呈递细胞的典型特征和功能,并表明这些细胞在神经再生过程中作为T细胞免疫负调节剂的新作用。

关键词： PD-L1 雪旺细胞抗原呈递细胞免疫能力免疫调节炎症神经损伤神经病变

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Plant Biosystems Design Research Roadmap 1.0

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BioDesign Research 2020年第1期2020卷 53-90页

作者： Xiaohan Yang June I.Medford Kasey Markel Patrick M.shih Henrique C.De Paoli Cong T.Trinh Alistair J.McCormick Raphael Ployet steven G.Hussey alexander A.Myburg Poul Erik Jensen Md Mahmudul Hassan Jin Zhang Wellington Muchero Udaya C.Kalluri Hengfu Yin Renying Zhuo Paul E.Abraham Jin-Gui Chen David J.Weston Yinong Yang Degao Liu Yi Li Jessy Labbe Bing Yang Jun Hyung Lee Robert W.Cottingham stanton Martin Mengzhu Lu Timothy J.Tschaplinski Guoliang Yuan Haiwei Lu Priya Ranjan Julie C.Mitchell stan D.Wullschleger Gerald A.Tuskan Biosciences Division Oak Ridge National LaboratoryOak RidgeTN 37831USA The Center for Bioenergy Innovation Oak Ridge National LaboratoryOak RidgeTN 37831USA Department of Biology Colorado State UniversityFort CollinsCO 80523USA Department of Plant Biology University of CaliforniaDavisDavisCAUSA Feedstocks Division Joint BioEnergy InstituteEmeryvilleCAUSA Department of Biodesign Biological Systems and Engineering DivisionLawrence Berkeley National LaboratoryBerkeleyCAUSA Department of Chemical and Biomolecular Engineering University of TennesseeKnoxvilleTN 37996USA synthsys and Institute of Molecular Plant sciences School of Biological SciencesUniversity of EdinburghEdinburgh EH93BFUK Department of Biochemistry Genetics and MicrobiologyForestry and Agricultural Biotechnology Institute(FABI)University of PretoriaPretoria 0002South Africa Department of Food science University of CopenhagenRolighedsvej 26DK-1858FrederiksbergCopenhagenDenmark state Key Laboratory of subtropical silviculture School of Forestry and BiotechnologyZhejiang A&F UniversityHangzhouZhejiang 311300China state Key Laboratory of Tree Genetics and Breeding Research Institute of Subtropical ForestryChinese Academy of ForestryHangzhouZhejiang 311400China Department of Plant Pathology and Environmental Microbiology and the Huck Institute of the Life sciences The Pennsylvania State UniversityUniversity ParkPA 16802USA Department of Genetics Cell Biology and DevelopmentCenter for Precision Plant Genomics and Center for Genome EngineeringUniversity of MinnesotaSaint PaulMN 55108USA Department of Plant science and Landscape Architecture University of ConnecticutStorrsCT 06269USA Division of Plant sciences Bond Life Sciences CenterUniversity of MissouriColumbiaMOUSA Donald Danforth Plant science Center St.LouisMOUSA Environmental sciences Division Oak Ridge National LaboratoryOak RidgeTN 37831USA

Human life intimately depends on plants for food,biomaterials,health,energy,and a sustainable *** plants have been genetically improved mostly through breeding,along with limited modification via genetic engineering,yet they are still not able to meet the ever-increasing needs,in terms of both quantity and quality,resulting from the rapid increase in world population and expected standards of living.A step change that may address these challenges would be to expand the potential of plants using biosystems design *** represents a shift in plant science research from relatively simple trial-and-error approaches to innovative strategies based on predictive models of biological *** biosystems design seeks to accelerate plant genetic improvement using genome editing and genetic circuit engineering or create novel plant systems through de novo synthesis of plant *** this perspective,we present a comprehensive roadmap of plant biosystems design covering theories,principles,and technical methods,along with potential applications in basic and applied plant biology *** highlight current challenges,future opportunities,and research priorities,along with a framework for international collaboration,towards rapid advancement of this emerging interdisciplinary area of ***,we discuss the importance of social responsibility in utilizing plant biosystems design and suggest strategies for improving public perception,trust,and acceptance.

关键词： Plant utilizing breeding

超快TWIsT-VIBE Dixon序列与扩散加权成像的联合成为准确且便于应用的乳腺MRI肿块分类工具

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国际医学放射学杂志 2020年第4期 497-497页

作者： s.C.Peter E.Wenkel E.Weiland M.Dietzel R.Janka A.Hartmann 马闻竟 Department of Radiology Erlangen University HospitalFriedrich-Alexander Universit?t Erlangen-Nürnberg (FAU)

目的本研究旨在开发一种联合超快TWIsTVIBE-Dixon(TVD)动态序列与扩散加权成像(DWI)序列的乳腺MRI肿块分类工具。虽然TVD序列可以简化乳腺MRI

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