检索结果-南通市图书馆

Parasites of the liver:A global problem?

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2024年第30期30卷 3554-3559页

作者： Vladislav V Tsukanov alexander V Vasyutin Julia L Tonkikh Clinical Department of the Digestive System Pathology of Adults and Children Federal Research Center“Krasnoyarsk Science Center”of the Siberian Branch of the Russian Academy of SciencesScientific Research Institute of Medical Problems of the NorthKrasnoyarsk 660022Russia

Parasitic liver diseases can be caused by trematodes,cestodes,nematodes,and *** pathology is significant because millions of people in different parts of the world have liver parasites,which can manifest themselves in the development of inflammation,liver cysts,cholecystitis,cholelithiasis,pancreatitis and liver cirrhosis that are often threatening their *** International Agency for Research on Cancer considers three species of trematodes,Schistosoma haematobium,Opisthorchis viverrini and Clonorchis sinensis,to be *** modern examination methods,in some cases including extensive screening of large populations,are required for diagnosing liver *** of parasitic liver diseases is differentiated and can involve a combination of surgical and therapeutic *** is no doubt that the clinical and epidemiological scale allows one to regard parasitic liver diseases as a global healthcare problem.

关键词： Liver Parasites Epidemiology Diagnosis Clinics Treatment Echinococcosis Opisthorchiasis Fascioliasis Schistosomiasis

New perspectives on biology,disease progression,and therapy response of head and neck cancer gained from single cell RNA sequencing and spatial transcriptomics

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Oncology Research 2024年第1期32卷 1-17页

作者： GERWIN HELLER THORSTEN FUEREDER alexander MICHAEL GRANDITS ROTRAUD WIESER Division of Oncology Department of Medicine IMedical University of ViennaVienna1090Austria Ludwig Boltzmann Institute for Hematology and Oncology Medical University of ViennaVienna1090Austria

Head and neck squamous cell carcinoma(HNSCC)is one of the most frequent cancers *** main risk factors are consumption of tobacco products and alcohol,as well as infection with human papilloma *** therapeutic options comprise surgery,radiation,chemotherapy,targeted therapy through epidermal growth factor receptor inhibition,and immunotherapy,but outcome has remained unsatisfactory due to recurrence rates of~50%and the frequent occurrence of second *** availability of the human genome sequence at the beginning of the millennium heralded the omics era,in which rapid technological progress has advanced our knowledge of the molecular biology of malignant diseases,including HNSCC,at an unprecedented ***,microarray-based methods,followed by approaches based on next-generation sequencing,were applied to study the genetics,epigenetics,and gene expression patterns of bulk *** recently,the advent of single-cell RNA sequencing(scRNAseq)and spatial transcriptomics methods has facilitated the investigation of the heterogeneity between and within different cell populations in the tumor microenvironment(e.g.,cancer cells,fibroblasts,immune cells,endothelial cells),led to the discovery of novel cell types,and advanced the discovery of cell-cell communication within *** review provides an overview of scRNAseq,spatial transcriptomics,and the associated bioinformatics methods,and summarizes how their application has promoted our understanding of the emergence,composition,progression,and therapy responsiveness of,and intercellular signaling within,HNSCC.

关键词： Head and neck squamous cell carcinoma Tumor microenvironment Immunotherapy Gene expression Omics

SmartMicro Grid Energy System Management Based on Optimum Running Cost for Rural Communities in Rwanda

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Energy Engineering 2024年第7期121卷 1805-1821页

作者： Fabien Mukundufite Jean Marie Vianney Bikorimana alexander Kyaruzi Lugatona Electrical and Electronic Engineering Department University of RwandaKigaliRwanda Electrical Engineering Department University of Dar es SalaamDar es SalaamTanzania

The governmental electric utility and the private sector are joining hands to meet the target of electrifying all households by ***,the aforementioned goal is challenged by households that are scattered in remote *** far,Solar Home Systems(SHS)have mostly been applied to increase electricity access in rural *** have continuous constraints to meet electricity demands and cannot run income-generating *** current research presents the feasibility study of electrifying Remera village with the smart microgrid as a case *** renewable energy resources available in Remera are the key sources of electricity in that *** generation capacity is estimated based on the load *** microgrid configurations are simulated with HOMER,and the genetic algorithm is used to analyze the optimum *** analyzing the impact of operation and maintenance costs,the results show that the absence of subsidies increases the levelized cost of electricity(COE)five times greater than the electricity price from the public *** microgrid made up of PV,diesel generator,and batteries proved to be the most viable solution and ensured continuous power supply to *** considering the subsidies,COE reaches 0.186$/kWh,a competitive price with electricity from public utilities in Rwanda.

关键词： Load demand load profile optimum running cost power demand satisfaction smart meters and smart micro grid

Understanding the eff ect of recreational drug use on bone health and musculoskeletal disease in the establishment of pain regimens

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Emergency Medicine 2024年第5期15卷 356-364页

作者： Ariella Gartenberg alexander Petrie Winston Yen Woojn Cho Emergency Medicine Department Montefi ore Medical Center and Jacobi Medical CenterNew York 10461USA Emergency Medicine Department Jacobi Medical Center and North Central BronxNew York 10461USA Touro College of Osteopathic Medicine Touro UniversityNew York 10027USA

BACKGROUND:The widespread use of recreational drugs has raised concerns regarding their eff ects on various organ *** use of cannabis and opioids in chronic pain management increases their prevalence among patients with musculoskeletal conditions whose bone health may already be *** article aims to review the pathophysiology and toxic eff ects of recreational drug use on musculoskeletal health to establish appropriate pain regimens for patients with substance ***:Medical literature published from 1970 until 2022 was identifi ed utilizing MEDLINE/PubMed and the Cochrane *** addition to the databases,references were obtained through the use of reference lists of published articles identifi ed by the aforementioned *** initial search terms included opioids,inhalants,hallucinogens,cannabis,stimulants,and bone *** were no methodological limitations in relation to the initial acquisition and analysis of ***:A total of 55 research articles were included in this ***,stimulants,opioids,and inhalants impact bone maintenance,specifically osteoblast and osteoclast activity,as well as impede hormone *** substances inhibit bone remodeling and development,manifesting as lower bone mineral density and increased fracture risk in chronic ***:Although the current literature suggests a deleterious effect of recreational drugs on bone health and musculoskeletal disease,further research is warranted to evaluate the clinical effects of long-term substance *** evaluation of such effects will aid in establishing appropriate pain regimens,as well as appropriate screening and treatment plans for recreational drug users.

关键词： Musculoskeletal disorders Bone health Cannabis Opioids Stimulants

Optical probing of ultrafast laser-induced solid-to-overdense-plasma transitions

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Light(Science & Applications) 2024年第5期13卷 973-984页

作者： Yasmina Azamoum Georg alexander Becker Sebastian Keppler Guillaume Duchateau Stefan Skupin Mickael Grech Fabrice Catoire Sebastian Hell Issa Tamer Marco Hornung Marco Hellwing alexander Kessler Franck Schorcht Malte Christoph Kaluza GSI Helmholtzzentrum für Schwerionenforschung Planckstr.164291 DarmstadtGermany. Helmholtz Institute Jena Fröbelstieg 307743 JenaGermany. Institute of Optics and Quantum Electronics Friedrich-SchillerUniversität JenaMax-Wien-Platz 107743 JenaGermany. CEA-CESTA 15 Avenue des SablièresCS6000133116 Le BarpCedexFrance Institut Lumière Matière UMR 5306-CNRSUniversitéde Lyon 169622 VilleurbanneFrance. LULI CNRSCEASorbonne UniversitéInstitut Polytechnique de ParisPalaiseauFrance. Universitéde Bordeaux-CNRS-CEA CELIAUMR 5107 TalenceFrance

Understanding the solid target dynamics resulting from the interaction with an ultrashort laser pulse is a challenging fundamental multi-physics problem involving atomic and solid-state physics,plasma physics,and laser *** of the initial interplay of the underlying processes is essential to many applications ranging from lowpower laser regimes like laser-induced ablation to high-power laser regimes like laser-driven ion *** the properties of the so-called pre-plasma formed as the laser pulse’s rising edge ionizes the target is complicated from the theoretical and experimental point of view,and many aspects of this laser-induced transition from solid to overdense plasma over picosecond timescales are still open *** the one hand,laser-driven ion acceleration requires precise control of the pre-plasma because the efficiency of the acceleration process crucially depends on the target properties at the arrival of the relativistic intensity peak of the *** the other hand,efficient laser ablation requires,for example,preventing the so-called“plasma shielding”.By capturing the dynamics of the initial stage of the interaction,we report on a detailed visualization of the pre-plasma formation and ***-thin diamond-like carbon foils are shown to transition from solid to plasma during the laser rising edge with intensitiesamics of an expanding plasma with densities above 10^(23)cm^(−3)(about 100 times the critical plasma density).The complementarity of a solid-state interaction model and kinetic plasma description provides deep insight into the interplay of initial ionization,collisions,and expansion.

关键词： laser acceleration solid

On the two-layer high-level Green-Naghdi model in a general form

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Hydrodynamics 2024年第1期36卷 78-86页

作者： Bin-bin Zhao Tian-yu Zhang Zhan Wang Wen-yang Duan alexander Chesnokov Natalia Shmakova College of Shipbuilding Engineering Harbin Engineering UniversityHarbin150001China Qingdao Innovation and Development Center of Harbin Engineering University Qingdao266000China Lavrentyev Institute of Hydrodynamics NovosibirskRussia

The traditional high-level Green-Naghdi(HLGN)model,which uses the polynomial as the shape function to approximate the variation of the horizontal-and vertical-velocity components along the vertical direction for each-fluid layer,can accurately describe the large-amplitude internal waves in a two-layer system for the shallow configuration(h_(2)/λ■1,h_(1)/λ■1).However,for the cases of the deep configuration(h_(2)/λ■1,h_(1)/λ=O(1)),higher-order polynomial is needed to approximate the variation of the velocity components along the vertical direction for the lower-fluid ***,however,introduces additional unknowns,leading to a significant increase in computational *** paper,for the first time,derives a general form of the HLGN model for a two-layer fluid system,where the general form of the shape function is used during the *** obtaining the general form of the two-layer HLGN equations,corresponding solutions can be obtained by determining the reasonable shape ***-amplitude internal solitary waves in a deep configuration are studied by use of two different HLGN *** of the two HLGN models shows that the polynomial as the shape function for the upper-fluid layer and the production of exponential and polynomial as the shape function for the lower-fluid layer is a good *** comparing with Euler’s solutions and the laboratory measurements,the accuracy of the two-layer HLGN model is verified.

关键词： High-level Green-Naghdi(HLGN)model general form internal waves deep configuration

Long-term Speckle Interferometric Monitoring of Binary Systems:2007–2023Positional Measurements and Orbits of Seven Objects

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research in Astronomy and Astrophysics 2024年第9期24卷 147-155页

作者： Arina Mitrofanova Vladimir Dyachenko Anatoly Beskakotov Yuri Balega alexander Maksimov Denis Rastegaev Special Astrophysical Observatory 369167 Nizhnij ArkhyzRussia

The results of seventeen years of speckle interferometric monitoring of seven objects(Chara 122Aa,GJ 3010,HIP1987,GJ 3076,HIP 11253,HIP 11352,and HIP 14929)are *** data were obtained at the 6 m Big Telescope Alt-azimuthal Special Astrophysical Observatory of the Russian Academy of Science(BTA SAO RAS)from 2007 to the *** of previously published and new measurements made it possible to construct completely new orbits for Chara 122Aa,HIP 11253,and HIP *** orbit of GJ 3076 cannot be constructed accurately due to the large influence of the weights assigned to the *** resulting orbital solutions are classified based on a grading scheme suggested by ***,*** and ***;most orbits are“definitive”(Grade 1).The mass sums and masses of components calculated by two independent methods using Hipparcos and Gaia DR2 and DR3 parallaxes were compared for the objects under study.

关键词： techniques:high angular resolution (stars:)binaries:visual stars:fundamental parameters stars:low-mass stars:solar-type

Reconstructing the Absorption Function in a Quasi-Linear Sorption Dynamic Model via an Iterative Regularizing Algorithm

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Advances in Applied Mathematics and Mechanics 2024年第1期16卷 237-252页

作者： Alexey Shcheglov Jingzhi Li Chao Wang alexander Ilin Ye Zhang Faculty of Computational Mathematics and Cybernetics Shenzhen MSU-BIT UniversityShenzhenGuangdong 518172China Faculty of Computational Mathematics and Cybernetics Lomonosov Moscow State UniversityMoscowRussia Department of Mathematics&National Center for Applied Mathematics Shenzhen&SUSTech International Center for Mathematics Southern University of Science and TechnologyShenzhenGuangdong 518055China School of Mathematics and Statistics Beijing Institute of TechnologyBeijing 100081China

This study addresses the parameter identification problem in a system of time-dependent quasi-linear partial differential equations(PDEs).Using the integral equation method,we prove the uniqueness of the inverse problem in nonlinear ***,using the method of successive approximations,we develop a novel iterative algorithm to estimate sorption *** stability results of the algorithm are proven under both a priori and a posteriori stopping rules.A numerical example is given to show the efficiency and robustness of the proposed new approach.

关键词： Inverse problem quasi-linear dynamic model uniqueness method of successive approximations stability

Structural and chemical transformations of CuZn alloy nanoparticles under reactive redox atmospheres:An in situ TEM study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2024年第7期17卷 6265-6273页

作者： Shengnan Yue Qian Li Chaobin Zeng alexander Klyushin Ramzi Farra Marc-Georg Willinger Xing Huang College of Chemistry Fuzhou UniversityFuzhou 350108China Qingyuan Innovation Laboratory Quanzhou 362801China Hitachi High-Tech Scientific Solutions(Beijing)Co. Ltd.Beijing 100015China MAX IV Laboratory Lund UniversityBox 11822100 LundSweden Department of Inorganic Chemistry Fritz-Haber Institute of Max Planck SocietyBerlin 14195Germany Department of Chemistry Technical University of MunichGarching 85748Germany

Alloying metals to form intermetallics has been proven effective in tuning the chemical properties of metal-based ***,intermetallic alloys can undergo structural and chemical transformations under reactive conditions,leading to changes in their catalytic *** and understanding these transformations are crucial for establishing relevant structureperformance relationships and for the rational design of alloy-based *** this work,we used CuZn alloy nanoparticles(NPs)as a model material system and employed in situ transmission electron microscopy(TEM)to investigate the structural and chemical changes of CuZn NPs under H_(2),O_(2)and their *** results show how CuZn NPs undergo sequential transformations in the gas mixture at elevated temperatures,starting with gradual leaching and segregation of Zn,followed by oxidation at the NP *** remaining copper at the core of particles can then engage in dynamic behavior,eventually freeing itself from the zinc oxide *** structural dynamics arises from an oscillatory phase transition between Cu and Cu_(2)O and is correlated with the catalytic water formation,as confirmed by in situ mass spectrometry(MS).Under pure H_(2)or O_(2)atmosphere,we observe different structural evolution pathways and final chemical states of CuZn NPs compared to those in the gas *** results clearly demonstrate that the chemical state of alloy NPs can vary considerably under reactive redox atmospheres,particularly for those containing elements with distinct redox properties,necessitating the use of in situ or detailed ex situ characterizations to gain relevant insights into the states of intermetallic alloy-based catalysts and structure-activity relationships.

关键词： In situ transmission electron microscopy(TEM) CuZn alloy structural and chemical transformations redox atmosphere