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Acute coronary syndromes： an old age problem

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Journal of Geriatric Cardiology 2012年第2期9卷 192-196页

作者： alexander D Simms Philip D Batin John Kurian Nigel Durham Christopher P Gale Centre for Epidemiology and Biostatistics Level 8 Worsley Building University of Leeds Clarendon Way West Yorkshire Leeds LS2 9JT UK Hull and York Medical School York Teaching Hospital NHS Foundation Trust York Y031 8HE UK Department of Cardiology York Teaching Hospital NHS Foundation Trust York Y031 8HE UK Department of Cardiology Mid Yorkshire NHS Trust Wakefield WF1 4DG UK Department of Cardiology Bradford Teaching Hospital NHS Foundation Trust Bradford UK

The increasing population in older age will lead to greater numbers of them presenting with acute coronary syndromes （ACS）. This has implications on global healthcare resources and necessitates better management and selection for evidenced-based therapies. The elderly are a high risk group with more significant treatment benefits than younger ACS. Nevertheless, age related inequalities in ACS care are recognised and persist. This discrepancy in care, to some extent, is explained by the higher frequency of atypical and delayed presentations in the elderly, and less diagnostic electrocardiograms at presentation, potentiating a delay in ACS diagnosis. Under estimation of mortality risk in the elderly due to limited consideration for physiological tiailty, co-morbidity, cognitive/psychological impairment and physical disability, less input by cardiology specialists and lack of randomised, controlled trials data to guide management in the elderly may further confound the inequality of care. While these inequalities exist, there remains a substantial opportunity to improve age related ACS outcomes. The selection of elderly patients for specific therapies and medication regimens are unanswered. There is a growing need for randomised, controlled trial data to be more representative of the population and enroll those of advanced age with co-morbidity. A lack of reporting of adverse events, such as renal impairment post coronary angiography, in the elderly further limit risk benefit decisions. Substantial improvements in care of elderly ACS patients are required and should be advocated. Ultimately, these improvements are likely to lead to better outcomes post ACS. However, the improvement in outcome is not infinite and will be limited by non-modifiable factors of age-related risk.

关键词： Acute coronary syndromes Elderly patients Inequalities of care Evidenced-based treatments

Hepatic pseudotumor associated with Strongyloides infection:A case report

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World Journal of Hepatology 2023年第12期15卷 1338-1343页

作者： Jessica P Gialanella Tyler Steidl Kokkola Korpela Miral S Grandhi Russell C Langan H Richard alexander Rachel M Hudacko Brett L Ecker Department of Surgical Oncology Rutgers Cancer Institute of New JerseyNew BrunswickNJ 08901United States Rutgers New Jersey Medical School NewarkNJ 07103United States Department of Infectious Disease Cooperman Barnabas Medical CenterLivingstonNJ 07039United States Department of Pathology and Labratory Medicine Rutgers Robert Wood Johnson Medical SchoolNew BrunswickNJ 08901United States

BACKGROUND Strongyloides sterocoralis is a parasitic infection caused by a roundworm that is transmitted through soil contaminated with *** can infrequently cause hepatic abscesses in immunocompromised patients and is rarely reported to form hepatic lesions in immunocompetent *** SUMMARY We present a case study of a 45-year-old female who presented with right upper quadrant abdominal pain and constitutional symptoms for several *** imaging identified several malignant-appearing liver *** investigation,including serological testing and histopathologic examination,revealed the presence of serum Strongyloides antibodies and hepatic granulomas with extensive *** treatment with ivermectin for 2 wk,there was complete resolution of the liver lesions and associated *** This case highlights the importance of considering parasitic infections,such as Strongyloides,in the differential diagnosis of hepatic *** recognition and appropriate treatment can lead to a favorable outcome and prevent unnecessary invasive *** awareness among clinicians is crucial to ensure the timely diagnosis and management of such cases.

关键词： Hepatic tumor Liver mass Strongyloides sterocoralis Parasitology Case report

诊室强化与标准降压治疗对动态血压的影响：收缩压干预试验的动态血压研究结果

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中华高血压杂志 2016年第11期24卷 1099-1099页

作者： Drawz PE Pajewski NM Bates jt Bello NA Cushman WC Dwyer JP Fine LJ Goff DC Jr Haley WE Krousel-wood M McWilliams A Rifkin DE Slinin Y Taylor A Townsend R Wall B Wright jt Rahman M 赵狄(摘译) 练桂丽(审校) 无不详 sprint study research group

诊室强化降压治疗对动态血压的影响并不清楚。收缩压干预试验（systolic blood pressure intervention trial,SPRINT）动态血压补充研究的目的是评估诊室强化与标准降压治疗对动态血压的影响。在27个月随访期的前3周内获得897例SPRINT... 详细信息

诊室强化降压治疗对动态血压的影响并不清楚。收缩压干预试验（systolic blood pressure intervention trial,SPRINT）动态血压补充研究的目的是评估诊室强化与标准降压治疗对动态血压的影响。在27个月随访期的前3周内获得897例SPRINT受试者的动态血压数据。

关键词：强化降压治疗动态血压干预试验收缩压诊室标准受试者随访期

Comparason of Peri-Articular Multimodal Drug Injection with Femoral and Sciatic Nerve Block after Total Knee Arthroplasty

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多样性的群体空间设计——纽约韦登迪+肯尼迪办公室

Open Journal of Orthopedics（矫形学期刊） 2012年第4期

作者： Calum H. C. Arthur alexander M. wood Charles Leeson-Payne Steffen J. Breusch Orthopaedic Department Royal Infirmary of Edinburgh

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设计家 2014年第4期 106-113页

作者： Amale Andraos Dan wood Sam Dufaux Bruce Damonte Raymond Adams WORKac Tamicka Marcy Julcsi Futo Beth O’ Neill Elodie Le Roy Deborah Richards Michael alexander Nick Hopson Estelle Bordas

设计理念WORKac在设计韦登迪＋肯尼迪公司的纽约办公室时,把都市人口的密度作为首要参考因素,即最大限度地压缩个人的工作空间,而将设计重点转向扩充多样性的群体空间。由于在韦登迪＋肯尼迪公司工作需要高度协作,所以WORKac设计的会议... 详细信息

设计理念WORKac在设计韦登迪＋肯尼迪公司的纽约办公室时,把都市人口的密度作为首要参考因素,即最大限度地压缩个人的工作空间,而将设计重点转向扩充多样性的群体空间。由于在韦登迪＋肯尼迪公司工作需要高度协作,所以WORKac设计的会议空间尽可能宽广,以容纳各种规模的会议和聚会。

关键词：空间设计群体空间办公室多样性纽约设计理念

Technical Evaluation of Hybrid Clones of Corymbia spp. to Produce Market Pulp

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Paper And Biomaterials 2022年第3期7卷 1-6页

作者： Marcelo Moreira da Costa Ricardo de Carvalho Bittencourt Thales Augusto Pinto Coelho Nogueira Larissa Soares Silva Weslley Henrique Martins da Silva Sebastião Renato Valverde Gleison Augusto Dos Santos Daniel alexander Fernandes Coelho Claudilene Aparecida Alves Pena Department of Forest Sciences Federal University of VicosaVicosaMinas Gerais36570900Brazil Aperam BioEnergia Co. CapelinhaMinas Gerais39680000Brazil

This study presents hybrid clones of Corymbia *** by Aperam BioEnergia as potential substitutes for Eucalyptus wood in the pulp *** biomass of Eucalyptus *** compared with that of Corymbia *** performing modified kraft pulping and basic density *** were made by analyzing their respective mean annual increments of cellulose(MAI_(cel))and specific wood consumption(SWC),estimated using a kappa number of(19±1).The results showed that one of the hybrid clones(Corymbia citriodora×Corymbia torelliana,ID 4)had higher basic wood density,higher screened yield,better MAI_(cel#k19),and lower SWC than the other samples,reaching values of 0.608 t/m^(3),54.1%,24.6 ADt/ha/year(i.e.,air dry ton/hectare/year),and 2.74 m^(3)/ADt,***,clone ID 4 had the highest MAI_(cel)/SWC ratio score(8.98).Given its high forest productivity and low industrial cost compared with other samples,as well as its advantages over Eucalyptus ***,we concluded that clone ID 4 has great potential as an alternative biomass for pulp production.

关键词： Corymbia hybrids modified kraft pulping mean annual increments of cellulose(MAIcel) specific wood consumption(SWC)

Using Water Stable Isotopes to Trace Water Sources of Three Typical Japanese Tree Species under Heavy Rainfall Conditions

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Open Journal of Forestry 2020年第1期10卷 7-21页

作者： Qiqin Zhang M. Larry Lopez C. alexander C. Brandt Jordi Voltas Takeshi Nakatsuka Mónica Aguilera Bioenvironment Watershed Preservation Yamagata University Wakaba-Machi Tsuruoka Yamagata Japan Joint Research Unit CTFC-AGROTECNIO Lleida Spain Department of Crop and Forest Sciences Universitat de Lleida Lleida Spain Research Department Research Institute for Humanity and Nature Kita-KuKamigamo Motoyama Kyoto Japan

Stable isotopes of xylem water (18O and D) have been successfully used to determine sources of soil water for plant transpiration, but mainly in drought-prone environments. The water uptake strategies of three representative tree species in Japan, namely cedar (Cryptomeria japonica), larch (Larix kaempferi) and beech (Fagus crenata), were investigated using δ18O and δD of water (precipitation, soil and xylem), together with wood α-cellulose δ13C and δ18O, along one growing season. The study was carried out in the research forest of Yamagata University (Shonai region), a high precipitation area in Japan, which exceeds 3000 mm per year. Precipitation water δ18O and δD increased along the summer growing season, but oxygen and hydrogen isotopic composition of soil water remained essentially unchanged. In general, xylem water isotopes of cedar and larch followed the local meteoric water line, but beech xylem water was decoupled from soil and precipitation values in July and August. For this tree species, the xylem water isotopic records were more depleted than cedar and larch xylem water isotopic values and the precipitation water isotopic records, indicating that beech used more water from soil layers during July-August than the other two species, which mainly used newly-fallen precipitation. wood δ18O showed an opposite seasonal trend to the one found for xylem water, likely because of leaf water isotope enrichment, which was in turn controlled by seasonal transpiration rate. The higher δ13C values of cedar during summer suggested that this species had enhanced water-use efficiency during the growing season compared with the deciduous species larch and beech. Our results highlight different water use strategies among forest tree species even in areas where the annual water balance is far from limiting plant performance.

关键词： High Precipitation Water Use Stable Isotopes Xylem Water Soil Water

Terahertz emission from localized modes in one-dimensional disordered systems [Invited]

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Photonics Research 2018年第4期6卷 117-122页

作者： YONGQUAN ZENG GUOZHEN LIANG Bo QIANG Bo MENG Hou KUN LIANG SHAMPY MANSHA JIANPING LI ZHAOHUI L LIANHE LI alexander GILES DAVIES EDMUND HAROLD LINFIELD YING ZHANG YIDONG CHONG AND Qi JIE WANG Centre for Optoelectronics and Biophotonics School of Electrical and Electronic Engineering Nanyang Technological University 50 Nanyang Avenue Singapore 639798 Singapore Singapore Institute of Manufacturing Technology 2 Fusionopolis Way Singapore 138634 Singapore School of Physical and Mathematical Sciences Nanyang Technological University 21 Nanyang Link Singapore 637371 Singapore Institute of Photonics Technology Jinan University Guangzhou 510632 China State Key Laboratory of Optoelectronic Materials and Technologies School of Electronics and Information Technology Sun Yat-sen University Guangzhou 510275 China School of Electronic and Electrical Engineering University of Leeds Woodhouse Lane Leeds LS2 9JT UK

We demonstrate terahertz(THz) frequency laser emission around 3.2 THz from localized modes in one-dimensional disordered grating systems. The disordered structures are patterned on top of the double-metal waveguide of a THz quantum cascade laser. Multiple emission peaks are observed within a frequency range corresponding to the bandgap of a periodic counterpart with no disorder, indicating the presence of mode localization aided by Bragg scattering. Simulations and experimental measurements provide strong evidence for the spatial localization of the THz laser modes.

关键词： (290.4210) Multiple scattering (040.2235) Far infrared or terahertz (140.5965) Semiconductor lasers, quantumcascade.

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运用模糊聚类方法分析中药微量元素含量与药效的关系

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中国组织工程研究与临床康复 2007年第40期11卷 8127-8130页

作者：董顺福韩丽琴赵文秀董宏博刘建华雷钧涛吉林医药学院吉林省吉林市132013

目的:不同中药中各种微量元素的含量数据离散,从含量数据上很难说明不同药物的药物相似性,故运用模糊分类方法研究药物微量元素含量与药物疗效的关系,验证其在药物功效的相似性及不同种类中药定量指标评价方面的作用。方法:实验于2005-1... 详细信息

目的:不同中药中各种微量元素的含量数据离散,从含量数据上很难说明不同药物的药物相似性,故运用模糊分类方法研究药物微量元素含量与药物疗效的关系,验证其在药物功效的相似性及不同种类中药定量指标评价方面的作用。方法:实验于2005-10/2006-11在吉林省中医药管理局中药微量元素分析实验室完成。用原子吸收分光光度法检测合欢花、黄芪、石菖蒲、远志、山楂、银杏叶、人参、元肉、蒲黄、酸枣仁、苏木11种中药中钾、钠、钙、镁、铁、铬、镍、锰、铜、锌元素的含量,结合锌/铜比值、镁/钙比值,以数据极差法进行统计指标的标准化处理,以数量积法算出衡量被分类对象之间的相关系数,确定论域上的模糊矩阵。结果:相关系数r=0.50时,合欢花,石菖蒲,远志,人参,元肉,蒲黄,酸枣仁7种药物聚类相似;相关系数r=0.65时,合欢花,石菖蒲,元肉,蒲黄,酸枣仁5种药物聚类相似;r=0.75时,合欢花,石菖蒲,蒲黄3种药物聚类相似。研究还发现:药物中金属元素含量丰富,而且相关系数较大的药物,其药物疗效相似。结论:运用数学与化学计量学方法建立模糊聚类分析模型,可以把离散的数据标准化处理,确定论域上的模糊矩阵可以研究不同药物间的药效相似性,可以对不同种类的中药进行定量指标的明确评价。

关键词：金属元素中药模糊分类