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Achieving high union rates after first metatarsophalangeal joint arthrodesis:Radiographic outcomes and technical pitfalls

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World Journal of Orthopedics 2023年第6期14卷 436-442页

作者： Christian von Deimling Timo Tondelli Samuel Brunner Octavian Andronic alexander david graf Department of Orthopedic Surgery and Traumatology Bürgerspital SolothurnSolothurn 4500Switzerland

BACKGROUND Fusion of the first metatarsophalangeal(MTP1)joint is a common surgery performed to correct hallux rigidus,hallux rigidus et valgus and other painful degenerative diseases of the *** To assess outcomes of our surgical technique including non-union rates,accuracy and aims of *** Between September 2011 and November 2020 a total 72 of MTP1 fusions were performed using a low profile,pre-contoured dorsal locking plate and a plantar compression *** and revision rates were analyzed with a minimum clinical and radiological follow up of at least 3 mo(range 3-18 mo).The following parameters were evaluated on pre-and postoperative conventional radiographs:Intermetatarsal angle,Hallux-valgus angle,dorsal extension of the proximal phalanx(P1)in relation to the floor and the angle between the Metatarsal 1 and the P1(MT1-P1 angle).Descriptive statistical analysis was *** analysis was used to assess for correlations between radiographic parameters and achievement of *** An overall union rate of 98.6%(71/72)was *** out of 72 patients did not primarily fuse with one patient suffering from a non-union,whilst the other demonstrating a radiological delayed union without clinical symptoms,with eventually complete fusion after 18 *** was no correlation between the measured radiographic parameters and the achievement of *** believe the reason for the non-union was mainly attributed to the patient’s incompliance without wearing the therapeutic shoe leading to a fracture of the ***,we didn`t find any correlation between fusion and the degree of *** With our surgical technique,high union rates(98%)can be achieved using a compression screw and a dorsal variable-angle locking plate to treat degenerative diseases of the MTP1.

关键词： Arthrodesis First metatarsophalangeal joint Dorsal plate Arthrodesis

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Hydroprocessing and Blending of a Biomass-Based DTG-Gasoline

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Energy Engineering 2022年第6期119卷 2169-2192页

作者： david graf Philipp Neuner Reinhard Rauch Department Fuel Technology(EBI-ceb) Karlsruhe Institute of Technology(KIT)Engler-Bunte-InstituteKarlsruhe76131Germany

The number of annually registered internal-combustion vehicles still exceeds electric-driven ones in most regions,e.g.,*** goals are disclosed with the European Green Deal,which calls for new technical approaches and greenhouse gas neutral transition *** bridging technologies are synthetic fuels for®the transportation sector,e.g.,using the bioliq process for a CO_(2)-neutral gasoline *** must meet the applicable national standards to be used in existing *** parameters can be variably adapted to their requirements by *** this work,we considered the upgrading of aromatic-rich DTG®gasoline from the bioliq *** heavy gasoline was therefore separated from the light one by *** investigated how to selectively modify the petrochemical parameters of the heavy gasoline,especially the boiling characteristics,to make the product suitable as a high-quality blending *** commercially available Pt/zeolite catalysts were tested over a wide range of temperature and space *** achieved high gasoline yields,while the content of light end compounds up to a boiling temperature of 150°C could be increased *** contrast to the high naphthenic content of the gasoline,the obtained octane numbers were *** the Motor Octane Number turned out unexpectedly high and showed a dependency on the isomerization of the naphthenic *** blending the upgraded heavy gasoline with the previously separated light gasoline,we could finally show that hydroprocessing is suitable for adjusting petrochemical *** aromatic concentration was 37.5%lower than that in the original raw gasoline,while the boiling characteristics improved ***,the final boiling point was 82°C lower,which is beneficial for the emission behavior.

关键词： Synthetic fuels upgrading durene dimethyl ether to gasoline refinery

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Volcanic Ash in the Atmosphere and Risks for Civil Aviation:A Study in European Crisis Management

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International Journal of Disaster Risk Science 2013年第1期4卷 9-19页

作者： david alexander Institute for Risk and Disaster Reduction University College London London WC1E 6BT United Kingdom

This paper uses the eruption of the Icelandic volcano Eyjafjallaj?kull in April and May 2010 as a case study of disruption to civil aviation by airborne ash, with emphasis on risk management aspects. Severe curtailment of flights over much of Europe took place during the crisis, which lasted for slightly more than one week. More than 8.5 million passengers were stranded and commerce was profoundly affected. The United Kingdom was one of the worst impacted countries and took the lead in managing the crisis. The paper considers elements of the decision-making process that formed the basis of the UK Government’s emergency response. It examines the relations between science, governance, and economi c imperatives. Physical thresholds guiding decisions to restrict airspace were defined somewhat arbitrarily, which may have increased disruption. A damaging form of risk aversion prevailed at certain points in the crisis. Lack of preexisting procedures and planning meant that the response to dynamically changing meteorological conditions had to be improvised. At the same time, lack of integration between different modes in the European transportation system meant that had the crisis continued any longer there would have been severe problems in moving stranded people and commodities, as well as soaring economic losses. Eruptions similar to or more serious than that of Eyjafjallaj?kull are perfectly possible in Europe in the not-too-distant future.

关键词： Atmosphere aviation meteorological

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One decade(2011–2020)of European agricultural water stress monitoring by MSG-SEVIRI:workflow implementation on the Virtual Earth Laboratory(VLab)platform

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International Journal of Digital Earth 2022年第1期15卷 730-747页

作者： Bagher Bayat Carsten Montzka alexander graf Gregory Giuliani Mattia Santoro Harry Vereecken Institute of Bio-and Geosciences:Agrosphere (IBG-3) Forschungszentrum Jülich GmbHJülichGermany Institute for Environmental Sciences EnviroSPACE labUniversity of GenevaGenevaSwitzerland Institute of Atmospheric Pollution Research National Research Council of Italy (CNR)Sesto FiorentinoItaly

Cloud computing facilities can provide crucial computing support for processing the time series of satellite data and exploiting their spatio-temporal information ***,dedicated efforts are still required to develop workflows,executable on cloud-based platforms,for ingesting the satellite data,performing the targeted processes,and generating the desired *** this study,an operational workflow is proposed,based on monthly Evaporative Stress Index(ESI)anomaly,and implemented in cloud-based online Virtual Earth Laboratory(VLab)platform,as a demonstration,to monitor European agricultural water *** this end,daily time-series of actual and reference evapotranspiration(ETa and ET0),from the Spinning Enhanced Visible and Infrared Imager(SEVIRI)sensor,were used to execute the proposed workflow successfully on *** execution of the workflow resulted in obtaining one decade(2011–2020)of European monthly agricultural water stress maps at 0.04˚spatial resolution and corresponding stress reports for each *** support open science,all the workflow outputs are stored in GeoServer,documented in GeoNetwork,and made available through *** enables creating a dashboard for better visualization of the results for *** results from this study demonstrate the capability of VLab platform for water stress detection from time series of SEVIRI-ET data.

关键词： ET SEVIRI ESI water stress workflow Europe VLab demonstration

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The conditional mitochondrial protein complexome in the Arabidopsis thaliana root and shoot

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Plant Communications 2023年第5期4卷 172-190页

作者： Youjun Zhang Silvia Martinez Jaime Mustafa Bulut alexander graf Alisdair R.Fernie Center of Plant Systems Biology and Biotechnology 4000 PlovdivBulgaria Max-Planck-Institut f€ur Molekulare Pflanzenphysiologie Am Muhlenberg 114476 Potsdam-GolmGermany

Protein complexes are important for almost all biological ***,to fully understand how cells work,it is also necessary to characterize protein complexes and their dynamics in response to various cellular ***,the dynamics of protein interaction play crucial roles in regulating the(dis)association of protein complexes and,in turn,regulating biological processes such as ***,mitochondrial protein complexes were investigated by blue native PAGE and size-exclusion chromatography under conditions of oxidative stress in order to monitor their dynamic(dis)*** of enzyme interactions and changes in protein complex abundance were observed in response to oxidative stress induced by menadione *** included changes in enzymatic protein complexes involving g-amino butyric acid transaminase(GABA-T),D-ornithine aminotransferase(D-OAT),or proline dehydrogenase 1(POX1)that are expected to affect proline *** treatment also affected interactions between several enzymes of the tricarboxylic acid(TCA)cycle and the abundance of complexes of the oxidative phosphorylation *** addition,we compared the mitochondrial complexes of roots and *** differences between the two tissues were observed in the mitochondrial import/export apparatus,the formation of super-complexes in the oxidative phosphorylation pathway,and specific interactions between enzymes of the TCA cycle that we postulate may be related to the metabolic/energetic requirements of roots and shoots.

关键词： mitochondrial complexes BN-PAGE size-exclusion chromatography TCA cycle

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On Evidence-Based Practice in Disaster Risk Reduction

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International Journal of Disaster Risk Science 2021年第6期12卷 919-927页

作者： david E.alexander Institute for Risk and Disaster Reduction University College LondonLondon WCIE 6BTUK

Disaster science and scholarship are forever expanding and there are increasing calls to base disaster risk reduction policies on the evidence produced by such *** examples and argument,this opinion piece examines the nature of *** defines evidence-based practice and considers how it has developed and become important to disaster risk reduction.A definition of what constitutes evidence is difficult to achieve but it must be made in relation to whether the data and information collected can usefully be interpreted and employed to change things for the *** histories from past and present centuries show that evidence can sometimes be argued over *** other cases it is roundly *** yet other instances,false conclusions derived from evidence can become evidence in their own ***,there are situations in disaster risk reduction in which evidence is sorely needed but is clearly *** effectiveness of counter-terrorism measures is one such *** conclusion,evidence is valuable,above all if there is willingness to use it to support policy formulation,especially in a simple,transparent *** interpretation can never be entirely removed from the use of evidence,and evidence alone will not stimulate the policy formulators to improve their decision making.

关键词： Case histories Disaster risk reduction Evidence-based practice Policy formulation

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On the Meaning of Impact in Disaster Risk Reduction

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International Journal of Disaster Risk Science 2022年第5期13卷 822-827页

作者： david E.alexander Institute for Risk and Disaster Reduction University College LondonLondon WC1E 6BTUK

This article offers a discussion of the meaning,assessment,and measurement of impact in disaster risk *** begins with a historical perspective on the impact of learned work in times when orthodoxy posed severe limits on the impact of new *** the modern age,the article explains why impact is considered important and how it might be recognized when it occurs,including a tentative classification of types of *** question of whether impact can truly be measured remains pending,as the answer is diffuse and dependent on many different *** sections consider the relationship between impact and mainstreaming and the question of whether a piece of work should be regarded as having impact if its effects are negative rather than ***,impact is considered in terms of whom it *** the large number of possible reservations about the concept,the question is raised as to whether too much emphasis is given to the impact of research and ***,some suggestions are offered regarding how to obtain a better indication of what the impact of an academic study actually is.

关键词： Assessing impact Disaster risk reduction Disruptive thinking Impact of research Mainstreaming disaster risk reduction Measuring impact

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OFF-GRID TINy HOUSE SMART RESIDENTIAL ENERGy MANAGEMENT SYSTEM

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Journal of Green Building 2016年第4期11卷 37-53页

作者： david G.alexander Department of Mechanical and Mechatronic Engineering California State UniversityChico

Students at California State University(CSU),Chico designed,built,and tested an off-grid solar powered tiny house and competed in the 2016 Sacramento Municipal Utility District’s(SMUD)Tiny House *** tier research institutions,predominantly undergraduate universities,and community colleges from all over California competed against one another in a variety of performance and aesthetic events in SMUD’s first ever *** of the main goals of the CSU,Chico’s Tiny House was to design and implement an autonomous energy management system to maximize energy capture,use,and efficiency and provide a seamless,comfortable,and uninterrupted indoor living *** system,smart residential energy management system(SREMS),was designed to monitor and sense solar energy collected and stored,indoor heating and cooling loads,occupant cooking and personal water heating needs,and electrical outlets and to determine and allow energy related activities given the amount of stored *** and heat transfer models were developed to predict heating,cooling,and appliance *** models were used to size the solar array,battery storage,and *** was installed in the tiny house and its performance was tested and validated during the week long SMUD Tiny House *** showed close correlation with the predicted energy requirements of the models,and the tiny house maintained net-zero energy use even during overcast and rainy skies throughout the three-day *** CSU,Chico team won best control system and best technology at the statewide *** paper describes the design,installation and testing results of CSU,Chico’s Tiny House SREMS.

关键词： Solar PV energy management tiny house student competition renewable energy sustainability

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An Abrupt Rainfall Decrease over the Asian Inland Plateau Region around 1999 and the Possible Underlying Mechanism

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Advances in Atmospheric Sciences 2017年第4期34卷 456-468页

作者： Jinling PIAO Wen CHEN Ke WEI Yong LIU Hans-F.graf Joong-Bae AHN alexander POGORELTSEV Center for Monsoon System Research Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100190China School of Earth Science University of the Chinese Academy of SciencesBeijing 100049China Department of Atmospheric Sciences Pusan National UniversityPusan 609-735Korea Russian State Hydrometeorological University St.Petersburg 195196Russia

A decadal change in summer rainfall in the Asian inland plateau（AIP） region is identified around 1999. This decadal change is characterized by an abrupt decrease in summer rainfall of about 15.7% of the climatological average amount,leading to prolonged drought in the Asian inland plateau region. Both the surface air temperature and potential evapotranspiration in the AIP show a significant increase, while the soil moisture exhibits a decrease, after the late 1990s. Furthermore,the normalized difference vegetation index shows an apparent decreasing trend during 1999–2007. Three different drought indices—the standardized precipitation index, the standardized precipitation evapotranspiration index, and the self-calibrating Palmer drought severity index—present pronounced climate anomalies during 1999–2007, indicating dramatic drought exacerbation in the region after the late 1990s. This decadal change in the summer rainfall may be attributable to a wave-like teleconnection pattern from Western Europe to Asia. A set of model sensitivity experiments suggests that the summer warming sea surface temperature in the North Atlantic could induce this teleconnection pattern over Eurasia, resulting in recent drought in the AIP region.

关键词： Asian inland plateau summer rainfall drought teleconnection pattern North Atlantic

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On a Measure of Non-compactness for Some Classical Operators

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Acta Mathematica Sinica,English Series 2006年第6期22卷 1847-1862页

作者： david E.EDMUNDS Alberto FIORENZA alexander MESKHI School of Mathematics Cardiff University Dipartimentodi Costruzioni e Metodi Matematici in Architettura Scuola Normale Superiore

The measure of non-compactness is estimated from below for various operators, including the Hardy-Littlewood maximal operator, the fractional maximal operator and the Hilbert transform, all acting between weighted Lebesgue spaces. The identity operator acting between weighted Lebesgue spaces and also between the counterparts of these spaces with variable exponents is similarly analysed. These results enable the lack of compactness of such operators to be quantified.

关键词： measure of non-compactness maximal functions singular integrals embeddings weight

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