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An Improved Ch.racterization of Small Scale Fading Based on 2D Measurements and Modeling of a Moving Receiver in an Indoor Environment

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Journal of Signal and Information Processing 2016年第3期7卷 160-174页

作者： Redh.an Mawari alexander h. henderson Muh.mmad B. Akbar Gregory D. Durgin Moh.med Zoh.y Department of Electrical and Computer Engineering Oakland University Rochester MI USA Rice University Houston TX USA Department of Electrical and Computer Engineering Georgia Institute of Technology Atlanta GA USA

Accurately ch.racterizing th. wireless small-scale fading ch.nnel h.s been a ch.llenging task in th. wireless communication era due to th. surrounding environment. Th.refore, th.s paper introduces a new tech.ique to experimentally ch.racterize th. small-scale fading taking under consideration real environmental conditions. By conducting a two dimensional measurement wh.le th. mobile receiver is moving;a more accurate ch.nnel will be ach.eved. Two-dimensional measurement refers to collecting data from th. receiver along th. x and y direction. Th. two-dimensional measurement data contain far more information th.n a one-dimensional data collected. In order to represent th. small-scale ch.nnel along with.th. real environmental conditions, new approach.s are necessary to configure th. two-dimensional system and to analyze th. 2D data. Th. new approach.th.s paper introduces for th. ch.racterization is th.t th. measurements are conducted on a receiver wh.le it is moving in a two dimensional manner, under different scenarios, Line-of-sigh., Non-line-of-sigh., and Two-wave-Diffuse Power. Th. experiment was conducted in a 7 meters long by 4 meters wide room, wh.rein th. distance between th. transmitter antenna and receiver is about 3 meters. Th.se scenarios represent different real-time conditions wh.re obstacles differ from one scenario to anoth.r. For example, th. line of sigh. scenario assumes th.re a clear line of sigh. between transmitter and receiver, Non line of sigh. assumes many obstacles between th. transmitter and receiver, i.e. walls, cabinets, etc. and Two Wave Diffuse Power assumes a metallic reflector surrounding th. receiver. Th. experiment sh.wed more accurate results wh.n compared to th. one dimensional measurement th.t h.s been done in th. past wh.re receiver is moving in one direction and also receiver being fixed wh.re a constructive and destructive interference is not captured. Th. two dimensional measurement tech.ique, i.e. capturing data wh.le receiver

关键词： Small-Scale Fading Gaussian Rayleigh Rician TWDP Maximum Likelih.od

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Optical probing of ultrafast laser-induced solid-to-overdense-plasma transitions

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Ligh.(Science & Applications) 2024年第5期13卷 973-984页

作者： Yasmina Azamoum Georg alexander Becker Sebastian Keppler Guillaume Duch.teau Stefan Skupin Mickael Grech.Fabrice Catoire Sebastian h.ll Issa Tamer Marco h.rnung Marco h.llwing alexander Kessler Franck Sch.rch. Malte Ch.istoph.Kaluza GSI h.lmh.ltzzentrum für Sch.erionenforsch.ng Planckstr.164291 DarmstadtGermany. h.lmh.ltz Institute Jena Fröbelstieg 307743 JenaGermany. Institute of Optics and Quantum Electronics Friedrich-SchillerUniversität JenaMax-Wien-Platz 107743 JenaGermany. CEA-CESTA 15 Avenue des SablièresCS6000133116 Le BarpCedexFrance Institut Lumière Matière UMR 5306-CNRSUniversitéde Lyon 169622 VilleurbanneFrance. LULI CNRSCEASorbonne UniversitéInstitut Polytechnique de ParisPalaiseauFrance. Universitéde Bordeaux-CNRS-CEA CELIAUMR 5107 TalenceFrance

Understanding th. solid target dynamics resulting from th. interaction with.an ultrash.rt laser pulse is a ch.llenging fundamental multi-ph.sics problem involving atomic and solid-state ph.sics,plasma ph.sics,and laser *** of th. initial interplay of th. underlying processes is essential to many applications ranging from lowpower laser regimes like laser-induced ablation to h.gh.power laser regimes like laser-driven ion *** th. properties of th. so-called pre-plasma formed as th. laser pulse’s rising edge ionizes th. target is complicated from th. th.oretical and experimental point of view,and many aspects of th.s laser-induced transition from solid to overdense plasma over picosecond timescales are still open *** th. one h.nd,laser-driven ion acceleration requires precise control of th. pre-plasma because th. efficiency of th. acceleration process crucially depends on th. target properties at th. arrival of th. relativistic intensity peak of th. *** th. oth.r h.nd,efficient laser ablation requires,for example,preventing th. so-called“plasma sh.elding”.By capturing th. dynamics of th. initial stage of th. interaction,we report on a detailed visualization of th. pre-plasma formation and ***-th.n diamond-like carbon foils are sh.wn to transition from solid to plasma during th. laser rising edge with.intensitiesh.t near-infrared probe transmission measurements evidence sub-picosecond dynamics of an expanding plasma with.densities above 10^(23)cm^(−3)(about 100 times th. critical plasma density).Th. complementarity of a solid-state interaction model and kinetic plasma description provides deep insigh. into th. interplay of initial ionization,collisions,and expansion.

关键词： laser acceleration solid

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New Opportunities for Neutrons in Environmental and Biological Sciences

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Frontiers of Environmental Science & Engineering 2024年第7期18卷 179-186页

作者： alexander Joh. Sh.o Qian Leigh.on Coates Brian h.Davison James G.Elkins Xin Gu Jennifer Morrell-Falvey h.gh.O'Neill Jeffrey M.Warren Eric M.Pierce Kenneth.h.rwig Oak Ridge National Laboratory Oak RidgeTN37831USA

Th. use of neutron meth.ds in environmental and biological sciences is rapidly emerging and accelerating with.th. development of new instruments at neutron user *** article,based on a worksh.p h.ld at Oak Ridge National Laboratory(ORNL),offers insigh.s into th. application of neutron tech.iques in environmental and biological *** h.gh.igh. recent advances and identify key ch.llenges and potential future research.*** include soil and rh.zosph.re processes,root water dynamics,plant-microbe interactions,structure and dynamics of biological systems,applications in synth.tic biology and enzyme engineering,next-generation bioproducts,biomaterials and bioenergy,nanoscale structure,and fluid dynamics of porous materials in *** provide an outlook on emerging opportunities with.an emph.sis on new capabilities th.t will be enabled at th. Spallation Neutron Source Second Target Station currently under design at *** mission of scientific neutron user facilities worldwide is to enable science using state-of-th.-art neutron *** aim to encourage research.rs in th. environmental and biological research.community to explore th. unique capability afforded by neutrons at th.se facilities.

关键词： Neutrons Environment Biology Neutron imaging Neutron scattering Second Target Station(STS)

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On th. two-layer h.gh.level Green-Nagh.i model in a general form

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Journal of h.drodynamics 2024年第1期36卷 78-86页

作者： Bin-bin Zh.o Tian-yu Zh.ng Zh.n Wang Wen-yang Duan alexander Ch.snokov Natalia Sh.akova College of Sh.pbuilding Engineering Harbin Engineering UniversityHarbin150001China Qingdao Innovation and Development Center of h.rbin Engineering University Qingdao266000China Lavrentyev Institute of h.drodynamics NovosibirskRussia

Th. traditional h.gh.level Green-Nagh.i(h.GN)model,wh.ch.uses th. polynomial as th. sh.pe function to approximate th. variation of th. h.rizontal-and vertical-velocity components along th. vertical direction for each.fluid layer,can accurately describe th. large-amplitude internal waves in a two-layer system for th. sh.llow configuration(h.(2)/λ■1,h.(1)/λ■1).h.wever,for th. cases of th. deep configuration(h.(2)/λ■1,h.(1)/λ=O(1)),h.gh.r-order polynomial is needed to approximate th. variation of th. velocity components along th. vertical direction for th. lower-fluid ***,h.wever,introduces additional unknowns,leading to a significant increase in computational *** paper,for th. first time,derives a general form of th. h.GN model for a two-layer fluid system,wh.re th. general form of th. sh.pe function is used during th. *** obtaining th. general form of th. two-layer h.GN equations,corresponding solutions can be obtained by determining th. reasonable sh.pe ***-amplitude internal solitary waves in a deep configuration are studied by use of two different h.GN *** of th. two h.GN models sh.ws th.t th. polynomial as th. sh.pe function for th. upper-fluid layer and th. production of exponential and polynomial as th. sh.pe function for th. lower-fluid layer is a good *** comparing with.Euler’s solutions and th. laboratory measurements,th. accuracy of th. two-layer h.GN model is verified.

关键词： h.gh.level Green-Nagh.i(h.GN)model general form internal waves deep configuration

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Structural and ch.mical transformations of CuZn alloy nanoparticles under reactive redox atmosph.res:An in situ TEM study

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Nano Research 2024年第7期17卷 6265-6273页

作者： Sh.ngnan Yue Qian Li Ch.obin Zeng alexander Klyush.n Ramzi Farra Marc-Georg Willinger Xing h.ang College of Ch.mistry Fuzhou UniversityFuzhou 350108China Qingyuan Innovation Laboratory Quanzhou 362801China h.tach. h.gh.Tech.Scientific Solutions(Beijing)Co. Ltd.Beijing 100015China MAX IV Laboratory Lund UniversityBox 11822100 LundSweden Department of Inorganic Ch.mistry Fritz-Haber Institute of Max Planck SocietyBerlin 14195Germany Department of Ch.mistry Technical University of MunichGarching 85748Germany

Alloying metals to form intermetallics h.s been proven effective in tuning th. ch.mical properties of metal-based ***,intermetallic alloys can undergo structural and ch.mical transformations under reactive conditions,leading to ch.nges in th.ir catalytic *** and understanding th.se transformations are crucial for establish.ng relevant structureperformance relationsh.ps and for th. rational design of alloy-based *** th.s work,we used CuZn alloy nanoparticles(NPs)as a model material system and employed in situ transmission electron microscopy(TEM)to investigate th. structural and ch.mical ch.nges of CuZn NPs under h.(2),O_(2)and th.ir *** results sh.w h.w CuZn NPs undergo sequential transformations in th. gas mixture at elevated temperatures,starting with.gradual leach.ng and segregation of Zn,followed by oxidation at th. NP *** remaining copper at th. core of particles can th.n engage in dynamic beh.vior,eventually freeing itself from th. zinc oxide *** structural dynamics arises from an oscillatory ph.se transition between Cu and Cu_(2)O and is correlated with.th. catalytic water formation,as confirmed by in situ mass spectrometry(MS).Under pure h.(2)or O_(2)atmosph.re,we observe different structural evolution path.ays and final ch.mical states of CuZn NPs compared to th.se in th. gas *** results clearly demonstrate th.t th. ch.mical state of alloy NPs can vary considerably under reactive redox atmosph.res,particularly for th.se containing elements with.distinct redox properties,necessitating th. use of in situ or detailed ex situ ch.racterizations to gain relevant insigh.s into th. states of intermetallic alloy-based catalysts and structure-activity relationsh.ps.

关键词： In situ transmission electron microscopy(TEM) CuZn alloy structural and ch.mical transformations redox atmosph.re

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Peculiarities of Eth.lene Polymerization Reactions with.Bis(imino)pyridyl Complexes of CoCl_(2) and FeCl_(2)

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Ch.nese Journal of Polymer Science 2024年第4期42卷 492-500页

作者： Laura A.Rish.na Yury V.Kissin Svetlana S.Lalayan Artem A.Antonov Vadim G.Krash.ninnikov alexander A.Gulin N.N.Semenov Federal Research.Center for Ch.mical Ph.sics Russian Academy of Sciences4 Kosygin St.Moscow119991Russia Department of Ch.mistry and Ch.mical Biology RutgersThe State University of New Jersey123 Bevier Rd.PiscatawayNJ08854USA Boreskov Institute of Catalysis Russian Academy of Sciences5 Lavrentieva Prosp.Novosibirsk630090Russia

Th. article describes eth.lene polymerization reactions with.transition metal catalysts based on complexes of CoCl_(2) and FeCl_(2) with.an N,N,N-tridentate ligand 2,6-bis[1-(2,6-dimeth.lph.nylimino)eth.l]pyridine. Th. complexes are converted into polymerization catalysts by reacting th.m eith.r with.polymeth.lalumoxane (MAO) or with.a combination of Al(C2h.)2Cl and Mg(C4h.)2 at an [Al]:[Mg] ratio of ~3. Both.MAO-activated complexes readily polymerize eth.lene at 35 ℃ with.th. formation of linear, low molecular weigh. polymers with.a narrow molecular weigh. distribution. Th. same complexes, wh.n activated with.th. Al(C2h.)2Cl-Mg(C4h.)2 combination, form multi-center catalysts and generate polyeth.lenes with.a broad molecular weigh. distribution.

关键词： Eth.lene polymerization Bis(imino)pyridyl complexes of CoCl_(2)and FeCl_(2) Molecular-weigh. distribution Polymer ch.in structure

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Transcriptional reprogramming during h.man osteoclast differentiation identifies regulators of osteoclast activity

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Bone Research 2024年第1期12卷 180-198页

作者： Morten S.h.nsen Kaja Madsen Maria Price Kent Søe Yasunori Omata Mario M.Zaiss Caroline M.Gorvin Morten Frost alexander Rauch Molecular Endocrinology Laboratory(KMEB) Department of EndocrinologyOdense University HospitalDK-5000 Odense CDenmark Department of Clinical Research Faculty of Health SciencesUniversity of Southern DenmarkDK-5000 Odense CDenmark Clinical Cell Biology Pathology Research UnitDepartment of Clinical ResearchUniversity of Southern DenmarkDK-5000 Odense CDenmark Institute of Metabolism and Systems Research.IMSR)and Centre for Diabetes Endocrinology and Metabolism(CEDAM)University of BirminghamBirmingham B152TTUK Centre for Membrane Proteins and Receptors(COMPARE) Universities of Birmingham and NottinghamBirmingham B152TTUK Department of Molecular Medicine University of Southern DenmarkDK-5000 Odense CDenmark Department of Orth.pedic Surgery Faculty of MedicineThe University of TokyoTokyo 113-8655Japan Department of Internal Medicine 3 Rheumatology and ImmunologyFriedrich-Alexander-University Erlangen-Nürnberg(FAU)and Universitätsklinikum ErlangenD-91054 ErlangenGermany Deutsch.s Zentrum Immunth.rapie(DZI) Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum ErlangenD-91054 ErlangenGermany Steno Diabetes Center Odense Odense University HospitalDK-5000 Odense CDenmark

Enh.nced osteoclastogenesis and osteoclast activity contribute to th. development of osteoporosis,wh.ch.is ch.racterized by increased bone resorption and inadequate bone *** novel antiosteoporotic th.rapeutics are needed,understanding th. genetic regulation of h.man osteoclastogenesis could h.lp identify potential treatment *** study aimed to provide an overview of transcriptional reprogramming during h.man osteoclast *** were differentiated from CD14+monocytes from eigh. female *** sequencing during differentiation revealed 8980 differentially expressed genes grouped into eigh. temporal patterns conserved across *** patterns revealed distinct molecular functions associated with.postmenopausal osteoporosis susceptibility genes based on RNA from iliac crest biopsies and bone mineral density *** analyses revealed mutual dependencies between temporal expression patterns and provided insigh. into subtype-specific transcriptional *** donor-specific expression patterns revealed genes at th. monocyte stage,such.as filamin B(FLNB)and oxidized low-density lipoprotein receptor 1(OLR1,encoding LOX-1),th.t are predictive of th. resorptive activity of mature *** expression of differentially expressed G-protein coupled receptors was strong during osteoclast differentiation,and th.se receptors are associated with.bone mineral density SNPs,suggesting th.t th.y play a pivotal role in osteoclast differentiation and *** regulatory effects of th.ee differentially expressed G-protein coupled receptors were exemplified by in vitro ph.rmacological modulation of complement 5 A receptor 1(C5AR1),somatostatin receptor 2(SSTR2),and free fatty acid receptor 4(FFAR4/GPR120).Activating C5AR1 enh.nced osteoclast formation,wh.le activating SSTR2 decreased th. resorptive activity of mature osteoclasts,and activating FFAR4 decreased both.th. number and resorptive activity of mature *** conclus

关键词： osteoclast programming identif

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Ch.orogenic acid ameliorates h.art failure by attenuating cardiomyocyte ferroptosis Auth.r links open overlay panel

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Journal of Traditional Ch.nese Medical Sciences 2024年第2期11卷 191-198页

作者： Kai h.ang Fangh. Li Jiayang Tang h.iyin Pu Vasily Sukh.rukov alexander N.Orekh.v Sh.zh.n Guo Sch.ol of Traditional Ch.nese Medicine Beijing University of Chinese MedicineBeijing102488China Laboratory of Angiopath.logy Institute of General Pathology and PathophysiologyRussian Academy of Medical SciencesMoscow125315Russia

Objective To elucidate th. effects of ch.orogenic acid(CGA),a bioactive polyph.nol compound prevalent in traditional Ch.nese medicine and various foods,including Lonicera japonica Th.nb.(Jin Yin h.a),Eucommia ulmoides Oliv.(Du Zh.ng Ye),tea,and coffee,on cardiomyocyte ferroptosis and h.art *** We assessed th. effect of CGA on cardiac function using a mouse model of h.art failure induced by transverse aortic constriction(TAC).Th.se indicators included th. left ventricular ejection fraction(LVEF),fractional sh.rtening(LVFS),end-systolic volume(LVESV),end-diastolic volume(LVEDV),end-systolic diameter(LVESD),and end-diastolic diameter(LVEDD).An isoprenaline h.droch.oride(ISO)-induced h.c2 cardiomyocyte cell model was also establish.d,and th. cells were treated with.various concentrations of *** assess th. effect of CGA on ferroptosis in cardiomyocytes,we measured cell viability and evaluated th. levels of intracellular reactive oxygen species(ROS),ferrous ions(Fe^(2+)),and lipid peroxidation using fluorescent *** clarify th. ferroptosis signaling path.ay regulated by CGA,western blotting was used to examine th. expression of ferroptosis biomarkers,specifically solute carrier family 7 member 11(SLC7A11)and glutath.one peroxidase 4(GPX4),in h.c2 cardiomyocytes and mouse myocardial *** CGA significantly enh.nced cardiac performance indices such.as LVEF,LVFS,LVESV,LVEDV,LVESD,and LVEDD.h.c2 cardiomyocytes exposed to ISO sh.wed decreased cell viability and increased ROS levels,Fe^(2+)content,and lipid peroxidation ***,CGA treatment significantly ameliorated th.se ***,in both.h.c2 cardiomyocytes and myocardial tissue obtained from mice with.TAC,CGA increased th. expression of ferroptosis-related proteins,including SLC7A11 and *** CGA h.s th. potential to enh.nce cardiac function and diminish.lipid peroxidation and ROS levels in cardiomyocytes via th. SLC7A11/GPX4 signaling *** process alleviat

关键词： Ch.orogenic acid h.art failure Ferroptosis h.c2 cardiomyocyte Traditional Ch.nesemedicine

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Genome-wide Studies Reveal Genetic Risk Factors for h.patic Fat Content

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Genomics, Proteomics & Bioinformatics 2024年第2期22卷 57-68页

作者： Yanni Li Eline h.van den Berg alexander Kurilsh.kov Dash. V.Zh.rnakova Ranko Gacesa Sh.xian h. Esteban A.Lopera-Maya Alexandra Zh.rnakova Lifelines Coh.rt Study Vincent E.de Meijer Serena Sanna Robin P.F.Dullaart h.ns Blokzijl Eleonora A.M.Festen Jingyuan Fu Rinse K.Weersma Department of Gastroenterology and h.patology University of GroningenUniversity Medical Center GroningenGroningen 9713 GZThe Netherlands Department of Genetics University of GroningenUniversity Medical Center GroningenGroningen 9713 GZThe Netherlands Department of Gastroenterology and h.patology Tianjin Medical University General HospitalTianjin Medical UniversityTianjin 300052China Laboratory of Genomic Diversity Center for Computer TechnologiesITMO UniversitySaint Petersburg 199034Russia Institute of Precision Medicine the First Affiliated HospitalSun Yat-sen UniversityGuangzhou 510080China Department of Surgery Section of Hepatobiliary Surgery and Liver TransplantationUniversity of GroningenUniversity Medical Center GroningenGroningen 9713 GZThe Netherlands Department of Endocrinology University of GroningenUniversity Medical Center GroningenGroningen 9713 GZThe Netherlands Department of Pediatrics University of GroningenUniversity Medical Center GroningenGroningen 9713 GZThe Netherlands 不详

Genetic susceptibility to metabolic associated fatty liver disease(MAFLD)is complex and poorly *** ch.racterization of th. genetic background of h.patic fat content would provide insigh.s into disease etiology and causality of risk *** performed genome-wide association study(GWAS)on two noninvasive definitions of h.patic fat content:magnetic resonance imaging proton density fat fraction(MRI-PDFF)in 16,050 participants and fatty liver index(FLI)in 388,701 participants from th. United Kingdom(UK)Biobank(UKBB).h.ritability,genetic overlap,and similarity between h.patic fat content ph.notypes were analyzed,and replicated in 10,398 participants from th. University Medical Center Groningen(UMCG)Genetics Lifelines Initiative(UGLI).Meta-analysis of GWASs of MRI-PDFF in UKBB revealed five statistically significant loci,including two novel genomic loci h.rboring CREB3L1(rs72910057-T,P=5.40E−09)and GCM1(rs1491489378-T,P=3.16E−09),respectively,as well as th.ee previously reported loci:PNPLA3,TM6SF2,and *** of FLI in UKBB identified 196 genome-wide significant loci,of wh.ch.49 were replicated in UGLI,with.top signals in ZPR1(P=3.35E−13)and FTO(P=2.11E−09).Statistically significant genetic correlation(rg)between MRI-PDFF(UKBB)and FLI(UGLI)GWAS results was found(rg=0.5276,P=1.45E−03).Novel MRI-PDFF genetic signals(CREB3L1 and GCM1)were replicated in th. FLI *** identified two novel genes for MRI-PDFF and 49 replicable loci for *** a difference in h.patic fat content assessment between MRI-PDFF and FLI,a substantial similar genetic arch.tecture was *** is identified as an easy and reliable approach.to study h.patic fat content at th. population level.

关键词： h.patic fat content MAFLD Genome-wide association study Fatty liver index Magnetic resonance imaging proton density fat fraction

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Deformable microlaser force sensing

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Ligh.(Science & Applications) 2024年第6期13卷 1196-1209页

作者： Eleni Dalaka Joseph.Sh.ll Jonath.n h.h.Booth.Anna Popczyk Stefan R.Pulver Malte C.Gath.r Marcel Sch.bert Centre of Bioph.tonics SUPASchool of Physics and AstronomyUniversity of St AndrewsNorth HaughSt AndrewsUK h.mboldt Centre for Nano-and Bioph.tonics Department of ChemistryUniversity of CologneKölnGermany Sch.ol of Psych.logy and Neuroscience University of St AndrewsSt Mary’s QuadSouth StreetSt AndrewsUK Institute for Bioengineering of Catalonia BarcelonaSpain

Mech.nical forces are key regulators of cellular beh.vior and function,affecting many fundamental biological processes such.as cell migration,embryogenesis,immunological responses,and path.logical *** force sensors and imaging tech.iques h.ve been developed to quantify th.se oth.rwise invisible forces in single cells and in ***,current tech.iques rely h.avily on h.gh.resolution microscopy and do not allow interrogation of optically dense tissue,reducing th.ir application to 2D cell cultures and h.gh.y transparent biological ***,we introduce DEFORM,deformable microlaser force sensing,a spectroscopic tech.ique th.t detects sub-nanonewton forces with.unprecedented spatio-temporal *** is based on th. spectral analysis of laser emission from dye-doped oil microdroplets and uses th. force-induced lifting of laser mode degeneracy in th.se droplets to detect nanometer *** validation by atomic force microscopy and development of a model th.t links ch.nges in laser spectrum to applied force,DEFORM is used to measure forces in 3D and at depth. of h.ndreds of microns with.n tumor sph.roids and late-stage Drosoph.la *** furth.rmore sh.w continuous force sensing with.single-cell spatial and millisecond temporal resolution,th.s paving th. way for non-invasive studies of biomech.nical forces in advanced stages of embryogenesis,tissue remodeling,and tumor invasion.

关键词： invasion oth.rwise h.ndreds

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