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Role of stem cell therapies in treating chronic wounds:A systematic review

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World Journal of Stem Cells 2020年第7期12卷 659-675页

作者： Anjali C Raghuram Roy P Yu Andrea Y Lo Cynthia J Sung Melissa Bircan Holly J Thompson alex K wong Division of Plastic and Reconstructive Surgery Keck School of Medicine of USCLos AngelesCA 90033United States Wilson Dental Library Herman Ostrow School of Dentistry of USCLos AngelesCA 90089United States

BACKGROUND The impairment of cutaneous wound healing results in chronic,non-healing wounds that are caused by altered wound environment oxygenation,tissue injury,and permissive microbial *** modalities for the treatment of these wounds inadequately address the complex changes involved in chronic wound ***,stem cell therapies have emerged as a potential therapeutic modality to promote cutaneous regeneration through trophic and paracrine *** To investigate current literature regarding use of stem cell therapies for the clinical treatment of chronic,non-healing *** PubMed,EMBASE,Cochrane Library,Web of Science,and Scopus were queried with combinations of the search terms“mesenchymal stem cells,”“adult stem cells,”“embryonic stem cells,”“erythroid precursor cells,”“stem cell therapies,”and“chronic wounds”in order to find relevant articles published between the years of 2000 and 2019 to review a 20-year *** lists from the articles were reviewed to identify additional pertinent *** manuscripts(reviews,case reports/series,retrospective/prospective studies,and clinical trials)were evaluated by the authors for their depiction of clinical stem cell therapy *** were extracted from the articles using a standardized collection *** A total of 43 articles describing the use of stem cell therapies for the treatment of chronic wounds were included in this *** stem cell therapies have been explored in in vitro and in vivo applications in the past,recent efforts are geared towards assessing their clinical role.A review of the literature revealed that adipose-derived stem cells,bone marrow-derived stem cells,bone marrowderived mononuclear cells,epidermally-derived mesenchymal stem cells,fibroblast stem cells,keratinocyte stem cells,placental mesenchymal stem cells,and umbilical cord mesenchymal stem cells have all been employed in the treatment of chronic wounds of various etiolo

关键词： Mesenchymal stem cells Adult stem cells Embryonic stem cells Erythroid precursor cells Stem cell therapies Chronic wounds

Harmonious growth in the chemical industry

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化工新型材料 2010年第S1期38卷 6-6页

作者： alex wong World Economic Forum

The Chemicals industry is the "industry of industries" as growth in many industries are dependent on the contin-ued innovation and harmonious growth of the chemicals *** on an analysis by the World Economic Forum, nine global trends present the greatest challenges and opportunities for this harmonious growth. This presentation will discuss how these trends impact the chemicals industry, and explore how actions can be taken in response at the global level, and in the context of China's next Five Year Plan.

关键词： Global Trends

Song of the Way in the Four Seasons:Venerable Master Chuanyin's Teaching Before Entering Final Retreat

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The Voice of Dharma 2020年第2期 93-96,167页

作者： Venerable Chuanyin alex wong(译) Venerable Zhenguan 不详

Foreword;Before my compassionate teacher Venerable Master Chuanyin(传印长老)entered his final retreat,which will last until he achieves liberation,he encouraged the assembly to engage in Pure Land practice,using his“... 详细信息

关键词： Master Way Season

Basic principles of aqueous cleaning in the industry

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Basic principles of aqueous cleaning in the industry

薄膜技术高峰论坛暨广东省真空学会学术年会

作者： alex wong Frank Lee Markus Borer Henry Ederle

Profile Specialist in functional and clean surfaces More than 40 years’ experience Global service and distribution network Innovative research and development ISO 9001:2000 and ISO 13485:2003 certified

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来源： cnki会议评论

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我国农村道路投资质量研究

农业技术经济 2014年第3期 4-15页

作者：罗仁福张林秀 alex wong Scott Rozelle 中国科学院农业政策研究中心北京100101 美国斯坦福大学国际研究中心加州943056055

在社会主义新农村建设过程中,如何在加大农村公共投资力度的同时确保农村公共投资质量成了一个备受关注的问题,其经济学本质是如何通过合理的制度安排解决公共投资中信息不对称、缺乏监督等导致的质量问题。在控制其他因素的作用后,完... 详细信息

在社会主义新农村建设过程中,如何在加大农村公共投资力度的同时确保农村公共投资质量成了一个备受关注的问题,其经济学本质是如何通过合理的制度安排解决公共投资中信息不对称、缺乏监督等导致的质量问题。在控制其他因素的作用后,完全由上级政府投资道路的质量评估得分显著比完全由村里投资道路的质量评估得分高,原因在于完全由上级政府投资的道路可以充分利用上级政府在道路项目设计和标准制定方面的管理优势,减少项目招投标阶段由于信息不对称带来的负面影响。在主要由上级政府投资的道路项目中,村集体对道路实施和管理的参与程度越高,道路项目质量评估得分也相对较高,原因在于村集体不仅更容易也更有积极性参与项目实施的监督,这些项目具体实施阶段的管理活动对于确保项目按最初设计和标准实施具有重要的作用。这一发现意味着上级政府通过加大公共投入力度,充分利用自身在项目设计、标准制定和招投标阶段的优势,同时村集体充分利用自身在项目具体实施阶段的管理和监督职能,能有效解决道路招投标和实施过程中存在的信息不对称等问题,提高道路投资质量。

关键词：道路质量融资结构项目管理标准制定信息不对称基础设施

The electroweak monopole–antimonopole pair in the standard model

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Communications in Theoretical Physics 2024年第3期76卷 113-119页

作者： Dan Zhu Khai-Ming wong Guo-Quan wong School of Physics Universiti Sains Malaysia11800 USMPenangMalaysia

We present the first numerical solution that corresponds to a pair of Cho–Maison monopoles and antimonopoles(MAPs) in the SU(2) × U(1) Weinberg–Salam(WS) *** monopoles are finitely separated,while each pole carries a magnetic charge ±4π/*** positive pole is situated in the upper hemisphere,whereas the negative pole is in the lower *** Cho–Maison MAP is investigated for a range of Weinberg angles,0.4675≤ tan θ_(W)≤10,and Higgs self-coupling,0 ≤ β ≤ *** magnetic dipole moment(μm) and pole separation(d_(z)) of the numerical solutions are calculated and *** total energy of the system,however,is infinite due to point singularities at the locations of monopoles.

关键词： magnetic monopole Cho-Maison monopole Weinberg-Salam model

Complex reconstruction of the lower extremity following sarcoma resection: a literature review

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Plastic and Aesthetic Research 2018年第1期5卷 16-27页

作者： Beina Azadgoli Antoine L.Carre David P.Perrault alex K.wong Division of Plastic and Reconstructive Surgery Department of SurgeryKeck School of Medicine of USCLos AngelesCA 90033USA

While amputation was traditionally the only option available for patients with sarcomas of the extremities, chemotherapy, radiation, and advances in microsurgical technique have allowed many patients to undergo limb-salvaging procedures. Given the low incidence and heterogeneity of these tumors, there is currently no standard treatment algorithm for limb reconstruction after large sarcoma resection. Thus, we systematically reviewed the various types of free tissue transfer used for the reconstruction of lower limbs after sarcoma resection. Techniques were described based on anatomic location. This literature review supports free tissue transfer as a safe and acceptable modality for reconstruction after sarcoma resection of the lower limb. It allows for the application of healthy vascularized tissue to the defect while also providing freedom of flap positioning. Flap choice is dependent on tumor and defect size, tissue type and function, as well as donor site availability.

关键词： Lower extremity sarcoma reconstruction

Prenatal diagnosis of choledochal cyst using magnetic resonance imaging: A case report

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World Journal of Gastroenterology 2005年第32期11卷 5082-5083页

作者： alex Mun-Ching wong Yun-Chung Cheung Yu-Hung Liu Koon-Kwan Ng Siu-Cheung Chan Shu-Hang Ng Department of Diagnostic RadiologyChang Gung Memorial Hospital Kwei-ShanTao-YuanTaiwanChina Obstetrics and GynecologyChang Gung Memorial Hospital 222Mei Chin RoadKeelungTaiwanChina

Choledochal cysts are congenital anomalies of the biliary ducts, characterized by cystic dilatation of the *** diagnosis of this anomaly using ultrasonography (US) has been well documented. Magnetic resonance imaging (MRI) has recently become an important complement to US in prenatal diagnosis of fetal anomalies. We herein report a patient in whom at 24 wk' gestation US suggested a right upper quadrant abdominal cyst and in whom at 26 wk' gestation MRI more clearly delineated the cyst and its surrounding structures and suggested a choledochal cyst, which was confirmed at postnatal surgery and histopathology.

关键词： Choledochal cyst Prenatal diagnosis MRI

Computed tomography findings in fatal cases of enormous hepatic portal venous gas

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World Journal of Gastroenterology 2005年第19期11卷 2953-2955页

作者： Siu-Cheung Chan Yung-Liang Wan Yun-Chung Cheung Shu-Hang Ng alex Mun-Ching wong Koon-Kwan Ng Department of Diagnostic Radiology Chang Gung Memorial Hospital Linko Medical Center and Keelung HospitalTaoyuanTaiwanChina

AIM: To assess the computed tomography (CT) findings in the patients with hepatic portal venous gas (HPVG) who presented with a short fatal clinical course in our hospital in order to demonstrate if there was any sign for ***: Between January 1997 and December 2000, CT scan of the abdomen was performed on 949 patients with acute abdominal pain in our emergency *** patients were found having HPVG. The CT images and clinical presentations of all these five patients were reviewed. RESULTS: In reviewing the CT findings of the cases, HPVG in bilateral hepatic lobes, abnormal gas in the superior mesenteric veins, small bowel intramural gas, and bowel distension were observed in all patients. Dry gas in multiple branches of the mesenteric vein was also revealed in all cases. All the patients expired due to irreversible septic shock within 48 h after their initial clinical presentation in emergency room. Two patients had acute pancreatitis with grade D and E Balthazar classification and they expired within 24 h due to progressing septic shock under aggressive medical treatment and life support. Two patients with underlying end stage renal disease expired within 48 h even though emergent surgical intervention was undertaken. The excited bowels revealed severe ischemic change. One patient expired only a few hours after the CT examination. CONCLUSION: HPVG is a diagnostic clue in patients with acute abdominal conditions, and CT is the most specific diagnostic tool for its evaluation. The dry mesenteric veins are the suggestive fatal sign, especially for the deteriorating patients, with the direct effect on gastrointestinal perfusion.

关键词： Hepatic portal vein Intestines Ischemia Computed tomography