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Chinese Journal of Chemistry 2023年第21期41卷 2801-2809页

作者： Raffaella Mancuso alex de salvo Patrizio Russo Aurelia Falcicchio Nicola della Ca’ Leonardo Pantoja Munoz Bartolo Gabriele Laboratory of Industrial and Synthetic Organic Chemistry(LISOC) Department of Chemistry and Chemical TechnologiesUniversity of CalabriaVia Pietro Bucci 12/C87036 Acavacata di Rende(CS)Italy Institute of Crystallography National Research CouncilVia Amendola122/O70126 BariItaly department of Chemistry Life Sciences and Environmental Sustainability(SCVSA)University of ParmaParco Area delle Scienze17/A43124 ParmaItaly department of Natural Sciences Faculty of Science and TechnologyMiddlesex UniversityThe BurroughsNW44BT LondonUK

The PdI_(2)/KI-catalyzed oxidative carbonylation of 4-(2-aminophenyl)-3-yn-1-ols,bearing two potential nucleophilic groups in suitable position selectively leads to dihydrofuroquinolinone derivatives in fair to high yields(60%—89%)and excellent turnover numbers(180—267 mol of product per mol of Pd)over 19 examples,through a mechanistic pathway involving initial O-cyclization followed by *** such process,the selective catalytic construction of two rings and three new bonds is achieved in one synthetic step to afford high value added fused heterocyclic structures starting from readily available materials.

关键词： Carbonylation Cyclization Heterocycles Palladium Polycyclic heterocycles

Conservation and modern architecture. Fortune and misfortune of the School of Mathematics at Rome University （G. Ponti, 1932-1935）

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Frontiers of Architectural Research 2015年第3期4卷 186-201页

作者： Simona salvo department of Architectural History Survey and Conservation 'Sapienza' University of Rome Rome 00185 Italy

The framework of the Italian restoration doctrine is based on the reception and transmission of the memory of the past. However, interventions in modern architecture represent a radical drift in the sense that they mostly consist of reconstructions, refurbishments, and renovations. Such work disresards the sense of value acknowledgment that is implicit in architectural conservation and neglects the importance of material conservation. The uneven fortune of the School of Mathematics at Rome＇s University Campus illustrates this situation. This predicament is similar to that of many other modern buildinss that have been declared ＂monuments＂ by mouth but are actually bent to listless and insensible use, mistreated, and hardly maintained. The recent work carded out at the School of Mathematics proves that interventions on modern buildings are mostly insensitive to their true significance and are often carded out in extreme urgency for mere practical reasons, if not for political opportunities. Modern buildings can be true architectural monuments that express great esthetic potentials and retain notable historical weight in the history of architecture; therefore, they should be regarded as highly representative of our recent past and maintained as such.

关键词： Conservation Restoration Modern architecture

Role of copper nanoparticles in wound healing for chronic wounds:literature review

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Burns & Trauma 2022年第1期10卷 805-813页

作者： Jessica salvo Cristian Sandoval Escuela de Enfermería Facultad de CienciasUniversidad MayorChile Programa de Doctorado en Ciencias Morfológicas Facultad de MedicinaUniversidad de la FronteraAv.Francisco Salazar 011454811230TemucoChile Escuela de Tecnología Médica Facultad de SaludUniversidad Santo TomásLos Carreras 7535310431OsornoChile departamento de Ciencias Preclínicas Facultad de MedicinaUniversidad de la FronteraAv.Francisco Salazar 011454811230TemucoChile

Chronic wounds are defined as wounds that fail to proceed through the normal phases of wound healing in an orderly and timely *** most common and inevitable impairment to wound healing is the installation of an infection,usually in the case of chronic ***,the objective of the present review was to identify the importance of copper nanoparticles in dressings for wound *** such as silver,gold and copper combat infectious processes through the inhibition of protein synthesis,peroxidation of the cell membrane and destroying the nucleic acids of bacteria and *** bioactive nanoparticles,copper plays a complex role in various cells,it modulates several cytokines and growth factor mechanisms of action and is essentially involved in all stages of the wound healing *** importantly,copper plays a key role in skin regeneration and angiogenesis and accelerates the healing process through induction of vascular endothelial growth factor(VEGF)and angiogenesis by hypoxia-induced factor-1-alpha(HIF-1α)action where copper enhances HIF-1αexpression and HIF-1αbinding to the critical motifs in the promoter and putative enhancer regions of HIF-1-regulated genes.

关键词： Angiogenesis Antimicrobial Nanoparticles Regeneration Wound healing Chronic wound VEGF HIF-1α

Natural vegetation cover in the landscape and edge effects： differential responses of insect orders in a fragmented forest

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Insect Science 2017年第5期24卷 891-901页

作者： Ezequiel Gonzalez Adriana salvo Graciela Valladares Centro de Investigaciones Entomologicas de Cordoba IMBIV UNC CONICET FCEFyN Av. Velez Sarfield 1611 Cordoba CordobaX5000GMC Argentina

Human activities have led to global simplification of ecosystems, among which Neotropical dry forests are some of the most threatened. Habitat loss as well as edge effects may affect insect communities. Here, we analyzed insects sampled with pan traps in 9 landscapes （at 5 scales, in 100-500 m diameter circles） comprising cultivated fields and Chaco Serrano forests, at overall community and taxonomic order level. In total 7043 specimens and 456 species of hexapods were captured, with abundance and richness being directly related to forest cover at 500 m and higher at edges in comparison with forest interior. Community composition also varied with forest cover and edge^interior location. Different responses were detected among the 8 dominant orders. Collembola, Hemiptera, and Orthoptera richness and^or abundance were positively related to forest cover at the larger scale, while Thysanoptera abundance increased with forest cover only at the edge. Hymenoptera abundance and richness were negatively related to forest cover at 100 m. Coleoptera, Diptera, and Hymenoptera were more diverse and abundant at the forest edge. The generally negative influence of forest loss on insect communities could have functional consequences for both natural and cultivated systems, and highlights the relevance of forest conservation. Higher diversity at the edges could result from the simultaneous presence of forest and matrix species, although ＂resource mapping＂ might be involved for orders that were richer and more abundant at edges. Adjacent crops could benefit from forest proximity since natural enemies and pollinators are well represented in the orders showing nositive edge effects.

关键词： Chaco Serrano edge effect forest cover habitat loss insects orders

Arthropods on plants in a fragmented Neotropical dry forest： A functional analysis of area loss and edge effects

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Insect Science 2015年第1期22卷 129-138页

作者： Ezequiel Gonzalez Adriana salvo Graciela Valladares Centro de Investigaciones Entomol6gicas de C6rdoba (IMBIV - CONICET) and Universidad Nacional de C6rdoba C6rdoba Argentina

Loss and fragmentation of natural ecosystems are widely recognized as the most important threats to biodiversity conservation, with Neotropical dry forests among the most endangered ecosystems. Area and edge effects are major factors in fragmented landscapes. Here, we examine area and edge effects and their interaction, on ensembles of arthropods associated to native vegetation in a fragmented Chaco Serrano forest. We analyzed family richness and community composition of herbivores, predators, and parasitoids on three native plant species in 12 fragments of varying size and at edge/interior positions. We also looked for indicator families by using Indicator Species Analysis. Loss of family richness with the reduction of forest fragment area was observed for the three functional groups, with sirnilar magnitude. Herbivores were richer at the edges without interaction between edge and area effects, whereas predators were not affected by edge/interior position and parasitoid richness showed an interaction between area and position, with a steeper area slope at the edges. Family composition of herbivore, predator, and parasitoid assemblages was also affected by forest area and/or edge/interior situation. We found three indicator families for large remnants and five for edges. Our results support the key role of forest area for conservation of arthropods taxonomic and functional diversity in a highly threatened region, and emphasize the need to understand the interactions between area and edge effects on such diversity.

关键词： area loss Chaco Serrano edge effect forest arthropods functional groups habitat fragmentation

Some stability results for a model of Hepatitis C including alanine aminotransferase and immune system

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International Journal of Biomathematics 2020年第8期13卷 157-185页

作者： salvo Danilo Lombardo Sebastiano Lombardo CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences Lazarettgasse 14AKH BT 25.3 A-1090 ViennaAustria department of Mathematics and Computer Science University of Catania(Ret.) 95125CataniaItaly

In clinical practice,many cirrhosis scores based on alanine aminotransferase(ALT)levels *** the most recent direct acting antivirals(DAAs)reduce fibrosis and ALT levels,the Hepatitis C virus(HCV)is not always *** this paper,we study a mathematical model of the HCV virus,which takes into account the role of the immune system,to investigate the ALT behavior during *** find five equilibrium points and analyze their stability.A sufficient condition for global asymptotical stability of the infeetion-free equilibrium is obtained and local asymptotical stability conditions are given for the immune-free infection and cytotoxic T lymphocytes(CTL)response *** stability of the infection equilibrium with the full immune response is numerically performed.

关键词： Hepatitis C virus(HCV) direct antiviral agents(DAAs) ordinary differential equations(Odes) equilibria stability basic reproduction number

Fatigue strength and microstructure evaluation of Al 7050 alloy wires recycled by spray forming,extrusion and rotary swaging

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Transactions of Nonferrous Metals Society of China 2020年第12期30卷 3195-3209页

作者： João G.J.de salvo Conrado RMAFONSO Programa de Pós-graduação em Ciência e Engenharia de Materiais(PPG-CEM) Universidade Federal de São Carlos(UFSCar)Rod.Washington LuizKm 23513565-905 São Carlos-SPBrazil Divisão de Materiais Instituto de Aeronáutica e EspaçoCTAPraça Marechal Eduardo Gomes5012228-904 São Josédos Campos-SPBrazil departamento de Engenharia de Materiais(deMa) Universidade Federal de São Carlos(USFCar)Rod.Washington LuizKm 23513565-905 São Carlos-SPBrazil

Recycled high-strength aluminum alloys have limited use as structural materials due to poor mechanical properties. Spray forming remelting followed by hot extrusion is a promising route for reprocessing 7 xxx alloys. The 7050 alloy machining chips were spray formed, hot extruded, rotary swaged and heat-treated in order to improve mechanical properties. Microstructures, tensile properties and fatigue strength results for a 2.7 mm-diameter recycled wire are presented. Secondary phases and precipitates were investigated by XRD, SEM, EBSD, TEM and DSC. As-swaged and heat-treated(solution and aging) conditions were evaluated. Mechanical properties of both conditions outperformed AA7050 aerospace specification. Substantial grain refinement resulted from the extensive plastic deformation imposed by rotary swaging. Refined micrometric and sub-micrometric Al grains, as well as coarse and fine intermetallic precipitates were observed. Subsequent solution treatment resulted in a homogeneous, recrystallized and equiaxed microstructure with grain size of 9 μm. Nanoscale GP(I) zones and η′ phase precipitates formed after aging at 120 ℃, imparting higher tensile(586 MPa) and fatigue(198 MPa) strengths.

关键词： Al−Zn−Mg−Cu alloy spray forming thermomechanical processing microstructure fatigue

Public health research on physical activity and COVID-19:Progress and updated priorities

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Journal of Sport and Health Science 2023年第5期12卷 553-556,F0003页

作者： James F.Sallis deepti Adlakha Adewale Oyeyemi deborah salvo Herbert Wertheim School of Public Health and Human Longevity Science University of California San DiegoLa JollaCA 92093-0631USA Mary Mackillop Institute for Health Research Australian Catholic UniversityMelbourneVIC 3000Australia department of Landscape Architecture and Environmental Planning College of DesignNorth Carolina State UniversityRaleighNC 27605USA College of Health Solutions Arizona State UniversityPhoenixAZ 85004USA department of Kinesiology and Health Education The University of Texas at AustinAustinTX 78712USA

*** Before coronavirus disease 2019 (COVID-19) became a global health emergency in early 2020,there was substantial evidence of physical activity’s (PA’s) multiple benefits with direct relevance to reducing the harms of the pandemic:improved immune functioning and reduced inflammation to lessen severity of infections,enhanced efficacy of vaccines.

关键词： inflammation severity vaccines

In situ microtomography investigation of microstructural evolution in Al-Cu alloys during holding in semi-solid state

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中国有色金属学会会刊：英文版 2010年第S3期20卷 734-738页

作者： S.TERZI L.salvo M.SUERY A.DAHLE E.BOLLER Australian Research Council Centre of Excellence for design in Light Metals Materials EngineeringThe University of QueenslandBrisbane Queensland 4072Australia Université de Grenoble Science et Ingénierie des Matériaux et ProcédésGénie Physique et Mécanique des MatériauxUMR CNRS 5266Grenoble INPUniversité Joseph FourrierBP4638402 Saint-Martin d'Hères CedexFrance European Synchrotron Radiation Facility 6 rue Jules HorowitzBP22038043 Grenoble CedexFrance

The aim of this paper is to report the results of experiments carried out on Al-Cu alloys with different Cu contents,studying the microstructure evolution during holding in the semi-solid *** 3-D microstructure was observed by in situ X-ray microtomography carried out at ESRF Grenoble,*** variation of the solid-liquid interface area per unit volume during holding was *** addition,local observations show that two coarsening mechanisms of the solid particles occur simultaneously:dissolution of small particles to the benefit of larger ones by an Ostwald-type mechanism and the growth of necks between solid particles due to *** observations confirm that in situ X-ray tomography is a very powerful tool to study the microstructure evolution in the semi-solid state and the influencing mechanisms in real-time.

关键词： Al-Cu alloys microtomography remelting microstructure

An international physical activity and public health research agenda to inform coronavirus disease-2019 policies and practices

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Journal of Sport and Health Science 2020年第4期9卷 328-334页

作者： James F.Sallis deepti Adlakha Adewale Oyeyemi deborah salvo department of Family and Preventive Medicine University of California San DiegoLa JollaCA 92093USA Mary Mackillop Institute for Health Research Australian Catholic UniversityMelbourne 3000Australia School of Natural and Built Environment Queen’s University BelfastBelfast BT95AGUK department of Physiotherapy College of Medical SciencesUniversity of MaiduguriMaiduguri 600243Nigeria Prevention Research Center Brown SchoolWashington University in St.LouisSt.LouisMO 63130USA

Physical activity(PA)has strong relevance for limiting the harms to human health and well-being due to the coronavirus disease-2019(COVID-19)pandemic.1 Active muscles produce chemicals that improve immune functioning,which in turn reduces the extent of infections,and decreases inflammation,and these are the main causes of the lung damage from severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)*** is a powerful preventive and therapeutic intervention for the most common pre-existing chronic conditions that increase risk of severe COVID-19 infections and mortality.

关键词： inflammation mortality lung