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头孢曲松和环丙沙星静脉滴注治疗塞拉利昂儿童伤寒的对照研究

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临床和实验医学杂志 2011年第5期10卷 351-352页

作者：刘焕 alex J.d.Kanu 湖南省湘潭市妇幼保健院儿科湖南湘潭410011 塞拉利昂弗里敦市金哈门路政府医院内科

目的比较头孢曲松和盐酸环丙沙星治疗儿童伤寒的疗效。方法将216例无并发症的伤寒患儿随机分为两组,分别采用头孢曲松针剂(A组,n=118)和盐酸环丙沙星针剂(B组,n=98)治疗,比较两组疗效情况。结果两组显效率、总有效率、体温下降起始时间... 详细信息

目的比较头孢曲松和盐酸环丙沙星治疗儿童伤寒的疗效。方法将216例无并发症的伤寒患儿随机分为两组,分别采用头孢曲松针剂(A组,n=118)和盐酸环丙沙星针剂(B组,n=98)治疗,比较两组疗效情况。结果两组显效率、总有效率、体温下降起始时间、体温降至正常时间的差异均无统计学意义(P>0.05)。结论两种药物治疗儿童伤寒的疗效相当,除头孢曲松外环丙沙星也是非洲儿童治疗伤寒的良好选择。

关键词：儿童伤寒头孢曲松环丙沙星

Comparison of Advantages About 3d Laparoscopic Surgery in Postoperative Recovery

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International English Education Research 2016年第12期 3-4页

作者： Vencent alex A.Eraituu Antonino Iuies Saint Luke Medical Center Quezon City Philippines

Analyzing and discussing advantages of3d laparoscopic surgery in postoperative recovery Method： Selecting patients were treated by 2d laparoscopic surgery or 3d laparoscopic,surgery in our hospital from January 2015 to January 2016 as research subjects. According to different methods, we separate patients into two groups, and each group is 150 patients. The one is test group （3d laparoscopic surgery）, and the other is control group（2d laparoscopic surgery）. Observing two groups for some factors, such as probability of surgical injury, post-operative exhaust time, catheterization time, time of drainage tube placement and hospital time. Result： The magnification of3d laparoscopy image is significantly better than 2d laparoscopy. Error damage fraction of test group（2. 00%） is lower than control group （28.00%）, which effectively reduces the probability of total surgical errors and provides more accurate operation. At the same time, exhaust time, catheterization time, time of drainage tube placement and hospital time of test group are significantly lower than the control group, statistically significant （p〈0.05）. Conclusion： 3d laparoscopic surgery has characterizations of easy operation, small window, fast recovery and small probability of complications occurrence. The Hd vision is widen to improve the level of minimally invasive surgery and it is worthy of clinical application.

关键词： 3d laparoscopy post-operation effect

The use of thallium isotopes to trace ferromanganese sediments in the mantle sources of ocean island basalts

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The use of thallium isotopes to trace ferromanganese sedimen...

Aberrant calcium signalling downstream of mutations in TP53 and the PI3K/AKT pathway genes promotes disease progression and therapy resistance in triple negative breast cancer

International Conference on Continental Volcanism

作者： Sune G. Nielsen Mark Rehkamper Marc d. Norman alex N. Halliday department of Earth Sciences ETH ZurichSonneggstrasse 58092 ZurichSwitzerland GEMOCDepartment of Earth and Planetary Sciences2109 NSWAustralia department of Earth Sciences ETH ZurichSonneggstrasse 58092 ZurichSwitzerland Imperial CollegeLondonUnited Kingdom Research School of Earth Sciences Australian National UniversityCanberraAustralian Capital Territory 0200Australia department of Earth Sciences ETH ZurichSonneggstrasse 58092 ZurichSwitzerland Department of Earth SciencesUniversity of OxfordParks RoadOxfordOX1 3PRUnited Kingdom

＜正＞Ocean island basalts （OIB） are generally thought to be the surface expression of mantle plumes. One model infers that OIBs originate from a deep mantle source, which was previously contaminated with ocean crust that entered the mantle via subduction zones. Thallium is one of the heaviest elements in the periodic table （isotopes 203Tl and 205Tl） and has a large ionic radius, which makes it incompatible in mantle minerals and leads to its

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Cancer drug Resistance 2022年第3期5卷 560-576页

作者： alex J.Eustace Min Jie Lee Grace Colley Jack Roban Tim downing Paul J.Buchanan dCU Cancer Research Dublin City UniversityDublin D9Ireland National Institute Cellular Biotechnology Dublin City UniversityDublin D9Ireland School of Biotechnology Dublin City UniversityDublin D9Ireland School of Nursing Psychotherapyand Community HealthDublin City UniversityDublin D9Ireland

Triple-negative breast cancer(TNBC)is characterized as an aggressive form of breast cancer(BC)associated with poor patient *** the majority of patients,there is a lack of approved targeted ***,chemotherapy remains a key treatment option for these patients,but significant issues around acquired resistance limit its ***,TNBC has an unmet need for new targeted personalized medicine ***(Ca^(2+))is a ubiquitous second messenger that is known to control a range of key cellular processes by mediating signalling transduction and gene *** in Ca^(2+)through altered calcium channel expression or activity are known to promote tumorigenesis and treatment resistance in a range of cancers including *** evidence shows that this is mediated by Ca^(2+)modulation,supporting the function of tumour suppressor genes(TSGs)and *** review provides insight into the underlying alterations in calcium signalling and how itplays a key role in promoting disease progression and therapy resistance in TNBC which harbours mutations intumour protein p53(TP53)and the PI3K/AKT pathway.

关键词： Triple-negative breast cancer TP53 PI3K/AKT pathway calcium

Autonomous Wireless Sensors Network Based on Piezoelectric Energy Harvesting

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Open Journal of Antennas and Propagation 2016年第3期4卷 138-157页

作者： alex Mouapi Nadir Hakem Gilles Y. delisle Underground Communication Research Laboratory University of Québec in Abitibi-Témiscamingue Val d’Or Canada

Wireless sensor networks (WSNs) offer an attractive solution to many environmental, security and process monitoring. However, their lifetime remains very limited by battery capacity. Through the use of piezoelectric energy harvesting techniques, ambient vibration can be captured and converted into usable electricity to create selfpowering WSN which is not limited by finite battery energy. This paper investigates analytically and experimentally the performance of a WSN powered by a Piezoelectric Energy Harvesting System (PEHS) and a material block-level modeling considering most key energy consumption of a wireless sensor node in a star topology network is proposed. By using real hardware parameters of existing components, the proposed model is used to evaluate the energetic budget of the node. The sensor node performance is evaluated regarding transmit packet size, duty cycle and the number of nodes that can be deployed. From the spectral properties of the available vibration inside two moving vehicles (automobile and train), the maximal recoverable power for each type of vehicle is estimated. Using a PEHS based on a cantilever beam optimized for low-frequency applications, 6 mW power is recovered in the case of the train while a 12.5 mW power is reached in the case of the automobile. It is observed that the sink may not operate with the recovered energy. However, the sensor node can sense and transmit data with a maximum size of 105.5 kbits when the duty cycle is 4 × 10-15. It is also achieved that the node is most effective when the measured physical phenomena vary slowly, such as the variations in temperature due to thermal inertia. Considering an optimized PEHS based on non-linear processing, it is shown that the sink can operate for 190% improvement of the recovered power.

关键词： WSN Self-Powering PEHS Packet Size duty Cycle Energy Harvesting System

Application of pan-sharpening algorithm for correlative multimodal imaging using AFM-IR

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npj Computational Materials 2019年第1期5卷 714-722页

作者： Nikolay Borodinov Natasha Bilkey Marcus Foston Anton V.Ievlev alex Belianinov Stephen Jesse Rama K.Vasudevan Sergei V.Kalinin Olga S.Ovchinnikova Center for Nanophase Materials Science Oak Ridge National LaboratoryOak RidgeTN 37831USA department of Energy Environmental&Chemical EngineeringWashington University in St.LouisOne Brookings DriveSt.LouisMO 63130USA

The coupling of atomic force microscopy with infrared spectroscopy(AFM-IR)offers the unique capability to characterize the local chemical and physical makeup of a broad variety of materials with nanoscale ***,in order to fully utilize the measurement capability of AFM-IR,a three-dimensional dataset(2d map with a spectroscopic dimension)needs to be acquired,which is prohibitively time-consuming at the same spatial resolution of a regular AFM *** this paper,we provide a new approach to process spectral AFM-IR data based on a multicomponent pan-sharpening *** approach requires only a low spatial resolution spectral and a limited number of high spatial resolution single wavenumber chemical maps to generate a high spatial resolution hyperspectral image,greatly reducing data acquisition *** a result,we are able to generate highresolution maps of component distribution,produce chemical maps at any wavenumber available in the spectral range,and perform correlative analysis of the physical and chemical properties of the *** highlight our approach via imaging of plant cell walls as a model system and showcase the interplay between mechanical stiffness of the sample and its chemical *** believe our pan-sharpening approach can be more generally applied to different material classes to enable deeper understanding of that structure-property relationship at the nanoscale.

关键词： utilize modal walls

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别落单,你也可以朋友成群!

疯狂英语（初中天地） 2010年第9期 16-19页

作者： d’Arcy Lyness alex 小狐

最要好的朋友不在身边真难熬——也许是因为你转到新的学校或班级，又或者那天你因病在家休养。课间休息或午餐时间没有朋友在身边，感觉真孤独。你一直会这样吗？你希望交些新朋友，但是该如何结交他们呢？每个人似乎都有自己的朋友了... 详细信息

最要好的朋友不在身边真难熬——也许是因为你转到新的学校或班级，又或者那天你因病在家休养。课间休息或午餐时间没有朋友在身边，感觉真孤独。你一直会这样吗？你希望交些新朋友，但是该如何结交他们呢？每个人似乎都有自己的朋友了。但是你要记住，朋友总是多多益善的。

关键词：朋友课间休息班级学校

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*** 2．0安全策略：代码访问安全

MSdN开发精选 2005年第5期 118-120页

作者： J．d．Meier alex Mackman

管理员可以将代码访问安全性信任与***一起使用，以分离应用程序和限制其能访问的资源类型和可以执行的特权操作。在寄宿环境内，多个应用程序共享同一个服务器，能够将应用程序分离是尤为重要的。

关键词： *** 安全策略代码应用程序共享资源类型安全性管理员服务器分离

Tunica albuginea allograft： a new model of LaPeyronie＇s disease with penile curvature and subtunical ossification

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Asian Journal of Andrology 2014年第4期16卷 592-596页

作者： Ludovic Ferretti Thomas M Fandel Xuefeng Qiu Haiyang Zhang Hazem Orabi alex K Wu Lia Banie Guifang Wang Guiting Lin Ching-Shwun Lin Tom FLue department of Urology University of Bordeaux Bordeaux France department of Urology Knuppe Molecular Urology Laboratory University of California San Francisco San Francisco California USA Hospital d'lnstruction des Armees Robert Picque Villenave D'Ornon France 4department of Urology Assiut University Assiut Egypt. department of Urology Assiut University Assiut Egypt.

The pathophysiology of LaPeyronie＇s disease （Pd） is considered to be multifactorial, involving genetic predisposition, trauma, inflammation and altered wound healing. However, these factors have not yet been validated using animal models. In this study, we have presented a new model obtained by tunica albuginea allograft. A total of 40, 16-week-old male rats were used. Of these, 8 rats served as controls and underwent a 10 × 2-mm-wide tunical excisionwith subsequent autografting, whereas the remaining 32 underwent the same excision with grafting of the defect with another rat＇s tunica. Morphological and functional testing was performed at 1, 3, 7 and 12 weeks after grafting. Intracavernous pressure, the degree of penile curvature and elastic fiber length were evaluated for comparison between the allograft and control groups. The tissues were obtained for histological examination. The penile curvature was significantly greater in the allografted rats as compared with the control rats. The erectile function was maintained in all rats, except in those assessed at 12 weeks. The elastin fiber length was decreased in the allografted tunica as compared to control. SMAd2 expression was detected in the inner part of the allograff, and both collagen-Ⅱ- and osteocalcin-positive cells were also noted. Tunica albuginea （TA） allograft in rats is an excellent model of Pd. The persistence of curvature beyond 12 weeks and the presence of ossification in the inner layer of the TA were similar to those observed in men with Pd. Validation studies using this animal model would aid understanding of the Pd pathophysiology for effective therapeutic interventions.

关键词： allograft animal model osteogenesis penile curvature penile surgery peyronie's disease