检索结果-南通市图书馆

Plot investigation on rill flow resistance due to path tortuosity

International Soil and Water Conservation Research 2023年第4期11卷 602-609页

作者： Francesco G.Carollo Costanza Di Stefano alessio Nicosia Vincenzo Palmeri Vincenzo Pampalone Vito Ferro Department of Agricultural Food and Forest SciencesUniversity of PalermoViale delle ScienzeBuilding 490128PalermoItaly NBFC National Biodiversity Future Center90133PalermoItaly

The path tortuosity t is an indicator of rill morphology accounting for the deviation of the thalweg from a straight *** effect of t on flow resistance has been little investigated for *** paper reports the results of a plot investigation aimed to establish the suitable accuracy of the rill thalweg measurement to determine the tortuosity parameter and to test the reliability of a theoretical flow resistance *** rills were incised in clay soil(CS)and clay-loam soil(LS)and shaped by a clear flow *** three-dimensional Digital Terrain Models were created by the Structure from Motion *** rills on LS,an approximate thalweg was tracked by photo-interpretation,and a specific calculation routine was applied to identify the cross sections with a constant spacing *** actual rill thalweg was obtained as the line joining the lowest points of these *** the different tested d values,d=0.075 m was chosen to determine *** both CS and LS,the Darcy-Weisbach friction factorffeatured a non-monotonic relation with t,which was explained as the result of three additive components due to bed roughness,sediment transport,and localized energy losses due to *** effect of the former two components onff contrasts that of the third,resulting in a linearly decreasing f-t relationship and constant flow velocity for the three lowest tortuosity values,and an increased friction factor and reduced flow velocity for the highest tortuosity *** flow resistance law was positively tested,and the predicted friction factor was dependent on t.

关键词： Rill erosion Tortuosity Rill morphology Friction factor Rill flow resistance

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatitis C virus eradication with directly acting antivirals improves health-related quality of life and psychological symptoms

引用

World Journal of Gastroenterology 2019年第48期25卷 6928-6938页

作者： Silvia Nardelli Oliviero Riggio Davide Rosati Stefania Gioia alessio Farcomeni Lorenzo Ridola Department of Translational and Precision Medicine “Sapienza”University of RomeRome 00185Italy Department of Economics&Finance University of Rome“Tor Vergata”Rome 00185Italy

BACKGROUND Alterations in health-related quality of life(HRQoL)and neuropsychological disorders were described in the hepatitis C virus(HCV)*** several studies investigated the modifications of HRQoL after HCV eradication,no data exists on the modifications of neuropsychological *** To investigate the effect of directly acting antivirals(DAAs)treatment on HRQoL and neuropsychological *** Thirty nine patients with HCV infection underwent a neuropsychological assessment,including Zung-Self Depression-Rating-Scale,Spielberg State-Trait Anxiety Inventory Y1-Y2 and the Toronto-Alexithymia Scale-20 items before and after DAAs *** was detected by Short-Form-36(SF-36).RESULTS All HRQoL domains,but role limitation physical and bodily pain,significantly improved after ***,after DAAs treatment,all domains of HRQoL returned similar to those of *** neuropsychological test significantly improved after HCV eradication.A significant correlation was observed among each psychological test and the summary components of *** multiple linear regression analysis including each psychological test as possible covariates,Zung-Self Depression Rating Scale(Zung-SDS)score was independently and significantly related to summary components of the SF-36 in the basal state and the difference between Zung-SDS score before and after treatment was the only variable significantly and independently related to the modification of HRQoL induced by the *** Neuropsychological symptoms strongly influenced HRQoL in HCV patients and there was a significant improvement of neuropsychological tests and HRQoL after DAAs treatment.

关键词： Hepatitis C virus Health related quality of life Depression State and trait anxiety Alexithymia Directly acting antivirals

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Identification in Lupin Seed of a Serine- Endopeptidase Activity Cleaving between Twin Arginine Pairs and Causing Limited Proteolysis of Seed Storage Proteins

引用

Molecular Plant 2012年第5期5卷 1011-1019页

作者： Chiara Magni Fabio Sessa Gabriella Tedeschi Armando Negri alessio Scarafoni Alessandro Consonni Marcello Duranti Department of AgriFood Molecular Sciences Universita degli Studi di Milano Via Celoria 2 20133 Milano Italy Department of Animal Pathology Hygiene and Veterinary Public Health--Section of Biochemistry Universita degli Studi di Milano Italy

The occurrence of twin-arginine motifs （-R-R-） in the amino acid sequences of animal pro-proteins frequently defines the cleavage site（s） for their structural/functional maturation. No information is available on the presence and possible biological meaning of these motifs in the seed storage proteins. In this work, a novel endopeptidase activity with cleavage specificity to twin-arginine pairs has been detected in mature dry Lupinus albus seeds. The endopeptidase was tested with a number of endogenous and exogenous protein substrates, which were selected according to the pres- ence of one or more twin-arginine residue motifs in their amino acid sequences. The observed hydrolysis patterns were limited and highly specific. Partial proteolysis led to stable polypeptide fragments that were characterized by 1- and 2-D electrophoresis. Selected polypeptides were submitted to N-terminal amino acid sequencing and mass spectrometry anal- yses, These approaches, supported by bioinformatic analysis of the available sequences, allowed the conclusion that the polypeptide cleavage events had occurred at the peptide bonds comprised between twin-arginine residue pairs with all tested protein substrates. The endopeptidase activity was inhibited by 4-（2-AminoEthyl）Benzene-Sulphonyl Fluoride hy- drochloride （AEBSF）, leupeptin, and serine proteinase protein inhibitors, while it was not affected by pepstatin, trans- EpoxysuccinyI-L-leucylamido（4-guanidino）butane （E64）, and ethylenediaminetetraacetic acid （EDTA）, thus qualifying the Arg-Arg cleaving enzyme as a serine endopeptidase. The structural features of storage proteins from lupin and other legume seeds strongly support the hypothesis that the occurrence of an endopeptidase activity cleaving -R-R- bonds may be functional to facilitate their degradation at germination and possibly generate polypeptide fragments with specific biological activity.

关键词： Lupinus albus leguminous seeds twin-arginine residues proteolysis storage proteins proteolytic conver-sion N-terminal amino acid sequence analysis.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Spinal deformities in a wild line of Poecilia wingei bred in captivity:report of cases and review of the literature

引用

Asian Pacific Journal of Tropical Biomedicine 2013年第3期3卷 186-190页

作者： alessio Arbuatti Leonardo Della Salda Mariarita Romanucci Veterinary Practitioner Mozzagrogna(Chieti) Department of Comparative Biomedical Sciences Faculty of Veterinary MedicineUniversity of Teramo

Objective:To describe the occurrence of various spinal deformations in a captive-bred wild line of Poecilia wingei(***).Methods:Fish belonging to a wild line of *** caught from Laguna de Los Patos,Venezuela,were bred in an aquarium home-breeding system during a period of three years(2006-2009).The spinal curvature was observed to study spinal deformities in ***:Out of a total of 600 fish,22 showed different types of deformities(scoliosis,lordosis,kyphosis),with a higher incidence in ***,swimming and breeding of deformed fish were generally ***:Possible causes for spinal curvature in fish are discussed on the basis of the current *** it is not possible to determine the exact cause(s)of spinal deformities observed in the present study,traumatic injuries,nutritional imbalances,genetic defects or a combination of these factors can be supposed to be involved in the pathogenesis of such lesions.

关键词： Poecilia wingei Spinal deformities Scoliosis Lordosis Kyphosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Characterisation of Photocathodes Based on Pb Thin Film Deposited by UV Pulsed Laser Ablation

引用

Journal of Materials Science & Technology 2014年第1期30卷 37-40页

作者： Francisco Gontad Antonella Lorusso Giancarlo Gatti Massimo Ferrario Laura Gioia Passione Luana Persano Nicola Lovergine alessio Perrone Istituto Nazionale di Fisica Nucleare e Università del Salento Università del Salento Dipartimento di Matematica e Fisica "E.De Giorgi" Laboratori Nazionali di Frascati Istituto Nazionale di Fisica Nucleare Center for Biomolecular Nanotechnologies Istituto Italiano di Tecnologia Dipartimento di Ingegneria dell'Innovazione Università del Salento National Nanotechnology Laboratory(NNL)

This work deals with the deposition of lead （Pb） thin films by the UV pulsed laser ablation technique, for their further use as photocathode devices in superconducting radio frequency guns. Scanning electron microscopy and atomic force microscopy analyses were performed to study the morphological features of Pb thin films deposited on Si （100） and Nb substrates. The films showed a granular structure with a nearly fully covered surface only for that one deposited on Nb substrate. X-ray diffraction measurements indicate the growth of polycrystalline Pb thin films with a preferential orientation along （111） planes. Results of the photoemission performance of Pb thin film deposited on Nb substrate showed a very encouraging average value of quantum efficiency of 6 x 10-5 through a single-photon absorption process, promoting further studies in the realisation of Pb photocathodes by this technique.

关键词： Pulsed laser deposition Lead thin film Metallic photocathodes Quantum efficiency

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Osteosarcopenia in autoimmune cholestatic liver diseases:Causes,management,and challenges

引用

World Journal of Gastroenterology 2022年第14期28卷 1430-1443页

作者： Nicola Pugliese Ivan Arcari alessio Aghemo Andrea G Lania Ana Lleo Gherardo Mazziotti Department of Biomedical Sciences Humanitas UniversityPieve Emanuele 20090MilanItaly Division of Internal Medicine and Hepatology Department of GastroenterologyIRCCS Humanitas Research HospitalRozzano 20089MIItaly Department of Endocrinology Diabetology and Medical Andrology UnitIRCCS Humanitas Research HospitalRozzano 20089MIItaly

Primary biliary cholangitis and primary sclerosing cholangitis(PSC)are the most common cholestatic liver diseases(CLD)in adults and are both characterized by an immune *** primary biliary cholangitis is a model autoimmune disease,with over 90%of patients presenting very specific autoantibodies against mitochondrial antigens,PSC is considered an immune mediated *** is the most common bone disease in CLD,resulting in frequent fractures and leading to significant ***,sarcopenia is emerging as a frequent complication of chronic liver diseases with a significant prognostic impact and severe implications on the quality of life of *** mechanisms underlying osteoporosis and sarcopenia in CLD are still largely unknown and the association between these clinical conditions remains to be *** timely diagnosis,prevention,and management of osteosarcopenia are crucial to limit the consequences,there are no specific guidelines for management of osteoporosis and sarcopenia in patients with *** guidelines recommend screening for bone disease at the time of diagnosis of ***,the optimal monitoring strategies and treatments have not been defined yet and vary among *** herein aim to comprehensively outline the pathogenic mechanisms and clinical implications of osteosarcopenia in CLD,and to summarize expert recommendations for appropriate diagnostic and therapeutic approaches.

关键词： Cholestatic liver diseases Primary biliary cholangitis Primary sclerosing cholangitis Osteoporosis Sarcopenia

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatitis B virus/hepatitis D virus epidemiology: Changes over time and possible future influence of the SARS-CoV-2 pandemic

引用

World Journal of Gastroenterology 2021年第42期27卷 7271-7284页

作者： Caterina Sagnelli Mariantonietta Pisaturo Caterina Curatolo alessio Vinicio Codella Nicola Coppola Evangelista Sagnelli Department of Mental Health and Public Medicine Section of Infectious DiseasesUniversity of Campania Luigi VanvitelliNaples 80131Italy Department of Mental Health and Public Medicine University of CampaniaNaples 80135Italy

Hepatitis D virus(HDV)is a defective liver-tropic virus that needs the helper function of hepatitis B virus(HBV)to infect humans and *** is transmitted sexually or by a parenteral route,in co-infection with HBV or by super-infection in HBV chronic *** infection causes acute hepatitis that may progress to a fulminant form(7%-14%by super-infection and 2%-3%by HBV/HDV co-infection)or to chronic hepatitis(90%by HDV super-infection and 2%-5%by HBV/HDV co-infection),frequently and rapidly progressing to cirrhosis or hepatocellular carcinoma(HCC).Peg-interferon alfa the only recommended therapy,clears HDV in only 10%-20%of cases and,consequently,new treatment strategies are being *** endemicity progressively decreased over the 50 years from the identification of the virus,due to improved population lifestyles and economic levels,to the use of HBV nuclei(t)side analogues to suppress HBV replication and to the application of universal HBV vaccination *** changes are expected during the severe acute respiratory syndrome coronavirus-2 pandemic,unfortunately towards increased endemicity due to the focus of healthcare towards coronavirus disease 2019 and the consequently lower possibility of screening and access to treatments,lower care for patients with severe liver diseases and a reduced impulse to the HBV vaccination policy.

关键词： Hepatitis B virus/hepatitis delta virus SARS-CoV-2 COVID-19 Hepatitis delta virus infection Hepatitis D Hepatitis delta virus epidemiology

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The management of the long head of the biceps in rotator cuff repair:A comparative study of high *** tenodesis

引用

Journal of Sport and Health Science 2023年第5期12卷 613-618页

作者： Edoardo Franceschetti Edoardo Giovannetti de Sanctis alessio Palumbo Michele Paciotti Luca La Verde Nicola Maffulli Francesco Franceschi Department of Orthopaedic and Trauma Surgery Campus Biomedico University of RomeVia Alvaro del Portillo 20000100 RomeItaly Department of Orthopaedics and Traumatology Catholic UniversityAgostino Gemelli Hospital00100 RomeItaly Anca Surgical Center Via Francesco Maidalchini 20Roma00152RomeItaly Department of Musculoskeletal Disorders Via Salvador Allende4384081 BaronissiSalernoItaly Centre for Sports and Exercise Medicine Barts and The London School of Medicine and DentistryMile End Hospital275 Bancroft RoadLondon E14DGEnglandUK School of Pharmacy and Bioengineering Keele University School of MedicineThornburrow DriveStoke on Trent ST4EnglandUK

Background:Tenodesis of the long head of the biceps(LHB)is commonly undertaken during arthroscopic rotator cuff *** assessed the clinical and structural outcomes after high arthroscopic tenodesis(HAT)or mini-open subpectoral tenodesis(ST).We hypothesized that the clinical and structural results after HAT and ST are ***:We included 40 patients with rotator cuff tear and LHB *** patients(7 women and 13 men;mean age:57.9 years;range:56-63 years)were treated using HAT,and 20 patients(8 women and 12 men;mean age:58.5 years;range:55-64 years)were treated using *** evaluation was performed preoperatively and at 6 weeks,6 months,and 1 year after surgery,using the Constant Murley Score and Simple Shoulder Test scores;the LHB was evaluated using the LHB score.A Visual Analogue Scale was administered to all patients preoperatively and 2 days after ***:The postoperative total and pain subscale’s Constant scores were significantly higher in the ST ***,2 LHB score values were significantly different between the *** postoperative LHB total score in the ST and HAT groups averaged 86.9±4.1(mean±SD)points and 73.3±6.4 points,*** Pain/Cramps subscale in the ST and HAT groups averaged 47.1±5.9 and 33.2±4.6 points,*** 2 groups showed no difference in Visual Analogue Scale values(5.5 in the HAT group;5.8 in the ST group)*** patient in the HAT group reported a secondary onset of Popeye ***:Both high arthroscopic and mini-open ST of the LHB tendon produced reliably good functional results,but the ST group was associated with better postoperative clinical outcomes.

关键词： Long head of the biceps Shoulder Shoulder arthroscopy Subpectoral TenodesisTagedEnd

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

COVID-19 and the gastrointestinal tract:Source of infection or merely a target of the inflammatory process following SARS-CoV-2 infection?

引用

World Journal of Gastroenterology 2021年第14期27卷 1406-1418页

作者： Jacopo Troisi Giorgia Venutolo Meritxell Pujolassos Tanyà Matteo Delli Carri Annamaria Landolfi alessio Fasano Metabolomics Section Theoreo srl-Spin-off Company of the University of SalernoMontecorvino Pugliano 84090SAItaly Department of Chemistry and Biology“A.Zambelli” University of SalernoFisciano 84084SAItaly European Biomedical Research Institute of Salerno Salerno 84125SAItaly Department of Medicine Surgery and Dentistry“Scuola Medica Salernitana”University of SalernoBaronissi 84081SAItaly Mucosal Immunology and Biology Research Center and Center for Celiac Research Harvard Medical SchoolMassachusetts Gen Hosp ChildrenMucosal Immunology and Biology Research CenterBostonMA 02114United States

Gastrointestinal(GI)symptoms have been described in a conspicuous percentage of coronavirus disease 2019(COVID-19)*** clinical evidence is supported by the detection of viral RNA in stool,which also supports the hypothesis of a possible fecal-oral transmission *** involvement of GI tract in severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection is corroborated by the theoretical assumption that angiotensin converting enzyme 2,which is a SARS-CoV-2 target receptor,is present along the GI *** have pointed out that gut dysbiosis may occur in COVID-19 patients,with a possible correlation with disease severity and with complications such as multisystem inflammatory syndrome in ***,the question to be addressed is whether dysbiosis is a consequence or a contributing cause of SARS-CoV-2 *** such a scenario,pharmacological therapies aimed at decreasing GI permeability may be beneficial for COVID-19 *** the possibility of a fecal-oral transmission route,water and environmental sanitation play a crucial role for COVID-19 containment,especially in developing countries.

关键词： COVID-19 SARS-CoV-2 Gastrointestinal symptoms Gut microbiome Dysbiosis Zonulin Fecal-oral transmission

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Robotically assisted removal of pelvic splenosis fifty-six years after splenectomy: A case report

引用

World Journal of Clinical Cases 2021年第12期9卷 2868-2873页

作者： alessio Tognarelli Lorenzo Faggioni Anna Paola Erba Pinuccia Faviana Jacopo Durante Francesca Manassero Cesare Selli Department of Translational Research and New Technologies in Medicine and Surgery Section of UrologyUniversity of PisaPisa 56126Italy Department of Translational Research and New Technologies in Medicine and Surgery Section of Diagnostic and Interventional RadiologyUniversity of PisaPisa 56126Italy Department of Translational Research and New Technologies in Medicine and Surgery Section of Nuclear MedicineUniversity of PisaPisa 56126ItalyPisa 56126Italy Department of Surgical Medical and Molecular Pathology and Critical AreaSection of PathologyUniversity of PisaPisa 56126Italy

BACKGROUND‘Splenosis’is defined as the autotransplantation of splenic tissue following trauma or surgery,usually in the form of intraperitoneal *** proliferation of imaging techniques has resulted in increased unexpected discoveries of splenosis nodules,and achieving a differential diagnosis can be *** medicine studies have been playing an increasingly important role in this process,but the clinical significance of asymptomatic nodules remains *** SUMMARY We present a case of pelvic splenosis in a 73-year-old man diagnosed 56 years after a splenectomy during a computed tomography(CT)follow-up for B-cell lymphoma,presenting intense contrast enhancement of an 18 mm nodule in the right recto-vesical space.18F-fluorodeoxyglucose demonstrated weak metabolic *** histological diagnosis was deemed necessary,the nodule was easily removed with robotically assisted laparoscopy,together with another 6 mm left a paracolic *** latter was previously undiagnosed but retrospectively visible on the CT *** In a patient requiring differential diagnosis of splenosis nodules from lymphomarecurrence, the robotic approach provided a safe en bloc removal with shorthospitalization. The Da Vinci Xi robot was particularly helpful because its opticscan be introduced from all ports, facilitating visualization and lysis of multipleintra-abdominal adhesions.

关键词： Pelvic splenosis Computed tomography Nuclear medicine Robotically assisted laparoscopy Da Vinci Xi Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：