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中华核医学杂志 2003年第5期23卷 265-265页

作者：李立伟解放军空军总医院核医学科北京100036

笔者探讨了~18F-脱氧葡萄糖(FDG)PET显像对恶性肿瘤放疗后疗效评价、判断肿瘤局部残留的价值，现报道如下。

关键词： ^18F-FDG PET显像诊断恶性肿瘤放疗局部残留 ^18F-脱氧葡萄糖

Relative volume measured with magnetic resonance imaging is an articular collapse predictor in hematological pediatric patients with femoral head osteonecrosis

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World Journal of Radiology 2016年第8期8卷 750-756页

作者： Davide Ippolito alessandro Masetto Cammillo Talei Franzesi Pietro A Bonaffini Alessandra Casiraghi Sandro Sironi Department of Diagnostic Radiology School of MedicineSan Gerardo HospitalUniversity of Milano-Bicocca

AIM To assess the potential value of femoral head(FH) volume measurements to predict joint collapse, as compared to articular surface involvement, in posttreatment osteonecrosis(ON) in pediatric patients affected by lymphoproliferative *** Considering 114 young patients with lymphoproliferative diseases undergone a lower-limbs magnetic resonance imaging(MRI) examination between November 2006 and August 2012 for a suspected post-treatment ON, we finally considered a total of 13 cases(7 males, mean age 15.2 ± 4.8 years), which developed a FH ON lesions(n = 23). The MRI protocol included coronal short tau inversion recovery and T1-weighted sequences, from the hips to the ankles. During the follow-up(elapsed time: 9.2 ± 2 mo), 13/23 FH articular surface(FHS)developed articular deformity. The first MRI studies with diagnosis of ON were retrospectively analyzed, measuring FH volume(FHV), FHS, ON volume(ONV) and the articular surface involved by ON(ONS). The relative involvement of FHS, in terms of volume [relative volume(RV): ONV/FHV] and articular surface [relative surface(RS): ONS/FHS], was then *** By using receiver operating characteristic curve analysis(threshold of 23% of volume involvement), RV predicted articular deformity in 13/13 FHS [sensitivity 100%, specificity 90%, accuracy 95%, positive predictive value(PPV) 93%, negative predictive value(NPV) 100%]. Considering a threshold of 50% of articular involvement, RS predicted articular deformity in 10/13 femoral heads(sensitivity 77%, specificity 100%, accuracy 87%, PPV 100%, NPV 77%).CONCLUSION RV might be a more reliable parameter than RS in predicting FH deformity and could represent a potential complementary diagnostic tool in the follow-up of femoral heads ON lesions.

关键词： Osteonecrosis Volume Articular surface Lymphoproliferative diseases Femoral head Magnetic resonance imaging

潘生丁与乙酰唑胺负荷脑血流灌注显像的对比研究

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中华核医学杂志 2003年第5期23卷 276-278,T003页

作者：马宏星陈绍亮许兰文许开平石洪成李蓓蕾复旦大学附属中山医院核医学科

目的　探讨潘生丁负荷脑血流灌注显像的可行性。方法　 8例健康志愿者和 2 3例患者于 1周内先后进行静息、乙酰唑胺及潘生丁负荷脑血流灌注显像。自身比较静息负荷状态下的脑血流灌注情况。结果　健康志愿者的脑血流灌注双侧对称。患... 详细信息

目的　探讨潘生丁负荷脑血流灌注显像的可行性。方法　 8例健康志愿者和 2 3例患者于 1周内先后进行静息、乙酰唑胺及潘生丁负荷脑血流灌注显像。自身比较静息负荷状态下的脑血流灌注情况。结果　健康志愿者的脑血流灌注双侧对称。患者组中 8例正常 ;1例患者静息态脑局部血流灌注低下 ,潘生丁和乙酰唑胺负荷态正常 ;余 14例静息态局部脑血流灌注低下或正常 ,应用潘生丁乙酰唑胺后局部脑血流量更低或出现低灌注区。两药显示低血流储备区的能力无明显差异。

关键词：潘生丁乙酰唑胺负荷脑血流灌注显像脑血流储备功能脑血管扩张作用

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打造面料工厂的绿色界面

商学院 2012年第2期 I0004-I0004页

作者： Fabrizio alessandro Goggi

作为一手创建了REDA公司公父传讯部门的人，REDA之于Fabrizio alessandro Goggi的情感和挑战也都源于此。在担任REDA全球传媒总监前，Fabrizio往汉莎航空、Luxottica集团等知名公司任过职，

关键词：界面工厂面料知名公司 A公司 RED 航空集团

《临床证据》入选意大利国家继续医学教育项目

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中国循证医学杂志 2007年第5期7卷 392-396页

作者： Lorenzo Moja Ivan Moschetti alessandro Liberati Roberto Manfrini Christian Deligant Roberto Satolli Antonio Addis Nello Martini Pietro Dri 陈耀龙（译）刁骧（审校）意大利Cochrane中心 Istituto Marlo Negri意大利米兰 Zadig科学出版公司意大利米兰意大利药物署（AIFA）意大利罗马不详

尽管循证医学（EBM）对卫生政策和临床实践的影响尚未确定，但在意大利，人们对循证医学的兴趣却与日俱增。意大利医生的信息需求很大程度上仍依赖于药厂，而非无偏倚的循证资源。例如，近期一项调查显示：全科医生每周会接受11次医药... 详细信息

尽管循证医学（EBM）对卫生政策和临床实践的影响尚未确定，但在意大利，人们对循证医学的兴趣却与日俱增。意大利医生的信息需求很大程度上仍依赖于药厂，而非无偏倚的循证资源。例如，近期一项调查显示：全科医生每周会接受11次医药代表的来访。该调查表明医生认为药厂提供的信息完整且可靠性较高。

关键词：继续医学教育循证医学临床证据

双探头SPECT心肌灌注显像中位移伪影的实验研究

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中华核医学杂志 2003年第5期23卷 312-314页

作者：石洪成姚之丰陈绍亮刘文官朱玮珉陈曙光复旦大学附属中山医院核医学科上海200032

目的　探讨双探头SPECT心肌灌注显像时位移伪影的影像特征和识别方法。方法　将心脏模型置于检查床上 ,与受检患者的心脏方向一致。在图像采集过程中 ,模型依次沿相当于患者左右、头尾和前后方向分别在不同起始点、对不同帧数作一定距... 详细信息

目的　探讨双探头SPECT心肌灌注显像时位移伪影的影像特征和识别方法。方法　将心脏模型置于检查床上 ,与受检患者的心脏方向一致。在图像采集过程中 ,模型依次沿相当于患者左右、头尾和前后方向分别在不同起始点、对不同帧数作一定距离的位移。结果　位移伪影的共同特点是表现为室壁放射性分布不均匀 ,“热区”与“冷区”交替出现 ,在短轴上最早出现 ,且表现最为明显 ;伪影进一步发展会在水平长轴和垂直长轴上表现为心尖附近放射性稀疏或缺损 ,出现与相邻室壁伴行且形态相近的“伴影”。结论　位移伪影主要表现为室壁放射性分布不均 ,“热区”与“冷区”交替出现。

关键词：双探头SPECT心肌灌注显像位移伪影实验质量控制

Reorganization of the intravitreal therapy service with the use of a scoring system during Coronavirus disease 2019 pandemic in a tertiary referral center in Milan,Italy

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Annals of Eye Science 2020年第4期 80-82页

作者： Stefano Erba Manuela Mambretti Giada Ruggi Federica Borgaro alessandro David Antonio Scialdone Giuseppe Casalino Oftalmico Hospital ASST Fatebenefratelli SaccoMilanItaly

With the recent Coronavirus disease(COVID-19)pandemic we have experienced a sudden and dramatic change of our scheduled work in every field of medicine,including ophthalmology(1-3).Our Medical Retina(MR)service is usually overbooked because of the increasing demand of intravitreal treatments for exudative maculopathy(4,5).However with the ongoing pandemic and the restrictive measures adopted by our Government to limit the spread of the COVID-19 outbreak,only urgent cases have been allowed to attend the clinic during the pandemic ***,we had to swiftly reorganise and reschedule the planned activity of our *** electronic medical records(EMR),clinical notes and retinal imaging of patients booked in our MR service were reviewed in order to assess the eligibility of patients to attend the Clinic.

关键词： service Corona attend

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诺顿美术馆

现代装饰 2019年第7期 28-35页

作者： Norman Foster Spencer de Grey David Summerfield Michael Wurzel Bjorn Andersson alessandro Angelelli Rebekah Hieronymus Tandorn Prakobpol Eleonora Rosselli Yasuhiro Tohdoh Nigel Young 范嘉苑 Foster+Partners

近期,位于佛罗里达西棕榈滩的诺顿美术馆完成了翻新及扩建改造,Foster+Partners设计事务所在原有建筑的基础上加入了更多的画廊空间以及访客服务设施。美术馆所在场地如今被改造为一片葱郁的佛罗里达花园,为访客提供了一处体验艺术的户... 详细信息

近期,位于佛罗里达西棕榈滩的诺顿美术馆完成了翻新及扩建改造,Foster+Partners设计事务所在原有建筑的基础上加入了更多的画廊空间以及访客服务设施。美术馆所在场地如今被改造为一片葱郁的佛罗里达花园,为访客提供了一处体验艺术的户外场所,与此同时,也增强了建筑与自然景观的联系。

关键词：佛罗里达主入口

What is the best way to manage screening for infections and vaccination of inflammatory bowel disease patients?

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World Journal of Gastrointestinal Pharmacology and Therapeutics 2016年第3期7卷 387-396页

作者： Gianluca Andrisani alessandro Armuzzi Manuela Marzo Carla Felice Daniela Pugliese Alfredo Papa Luisa Guidi IBD Unit Complesso Integrato Columbus Università Cattolica del Sacro Cuore

The use of biological agents and immunomodulators for inflammatory bowel disease(IBD) is associated with an increased risk of opportunistic infections, in particular of viral or bacterial etiology. Despite the existence of international guidelines, many gastroenterologists have not adopted routine screening and vaccination in those patients with IBD, which are candidate for biologic therapy. Available strategies to screen, diagnose and prevent bacterial and viral infections in patients with IBD prior to start biological therapy are discussed in this review.

关键词： Inflammatory bowel disease Opportunistic infections Immunomodulators Corticosteroids Anti-tumor necrosis factor agents

Renal function and physical fitness after 12-mo supervised training in kidney transplant recipients

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World Journal of Transplantation 2018年第1期8卷 13-22页

作者： Giulio Sergio Roi Giovanni Mosconi Valentina Totti Maria Laura Angelini Erica Brugin Patrizio Sarto Laura Merlo Sergio Sgarzi Michele Stancari Paola Todeschini Gaetano La Manna Andrea Ermolao Ferdinando Tripi Lucia Andreoli Gianluigi Sella Alberto Anedda Laura Stefani Giorgio Galanti Rocco Di Michele Franco Merni Manuela Trerotola Daniela Storani alessandro Nanni Costa Department of Education and Research Isokinetic Medical Group Department of Nephrology and Dialysis Morgagni-Pierantoni Hospital Department of Biomedical & Neuromotor Sciences University of Bologna Associazione Nazionale Emodializzati Dialisi e Trapianto Department of Cardiovascular Sports Medicine Sports Medicine ULSS Company 9 Sports Medicine Regional Hospital of Bologna Department of Nephrology and Dialysis S. Orsola Hospital Sports Medicine Unit DIMED Department of Medicine University of Padua Sports Medicine Regional Hospital of Modena Sports Medicine Regional Hospital of Ravenna Sports Medicine Regional Hospital of Parma Department of Experimental and Clinical Medicine School of Sports Medicine University of Florence Sports Medicine Centre Italian National Transplant Centre

AIM To evaluate the effect of a 12-mo supervised aerobic and resistance training, on renal function and exercise capacity compared to usual care *** Ninety-nine kidney transplant recipients(KTRs) were assigned to interventional exercise(Group A; n = 52) and a usual care cohort(Group B; n = 47). Blood and urine chemistry, exercise capacity, muscular strength, anthropometric measures and health-related quality of life(HRQo L) were assessed at baseline, and after 6 and 12 mo. Group A underwent a supervised training three times per week for 12 mo. Group B received only general recommendations about home-based physical *** Eighty-five KTRs completed the study(Group A, n = 44; Group B, n = 41). After 12 mo, renal function remained stable in both groups. Group A significantly increased maximum workload(+13 W, P = 0.0003), V'O2 peak(+3.1 mL/kg per minute, P = 0.0099), muscular strength in plantar flexor(+12 kg, P = 0.0368), height in the countermovement jump(+1.9 cm, P = 0.0293) and decreased in Body Mass Index(-0.5 kg/m^2, P = 0.0013). HRQo L significantly improved in physical function(P = 0.0019), physical-role limitations(P = 0.0321) and social functioning scales(P = 0.0346). Noimprovements were found in Group *** Twelve-month of supervised aerobic and resistance training improves the physiological variables related to physical fitness and cardiovascular risks without consequences on renal function. Recommendations alone are not sufficient to induce changes in exercise capacity of KTRs. Our study is an example of collaborative working between transplant centres, sports medicine and exercise facilities.

关键词： Kidney transplant recipients Renal function Supervised exercise Aerobic exercise Muscle strength