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Challenges of Improving Intensive Care Medicine in Eritrea: Impact of an Italian Cooperative Project of Educational and Clinical Support

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Open Journal of Anesthesiology 2013年第7期3卷 315-319页

作者： Valentina Anichini Giovanni Zagli Hagos Goitom Giovanni Cianchi Andrea Cecchi Lucia Perretta Emanuele Bigazzi Barbara Gazzini Simone Proietti alessandro di filippo Simone Toccafondi Gianfranco Gensini Giancarlo Berni Adriano Peris Anesthesia and Intensive Care Unit of Emergency Department Careggi Teaching Hospital Florence Italy Anesthesia and Intensive Care Faculty of Medicine University of Florence Florence Italy Department Intensive Care Unit Orotta National Referral Hospital Asmara Eritrea Department of Critical Care Medicine and Surgery Careggi Teaching Hospital Florence Italy First Aid of Emergency Department Careggi Teaching Hospital Florence Italy Tuscany Region Sanitary System Florence Italy.

Intensive care in Africa is available only in teaching or referral hospitals. Here we report the experience of a multidisciplinary collaboration between physicians and nurses of the Emergency Department (First Aid and Intensive Care Unit) of a tertiary referral hospital (Careggi Teaching Hospital, Florence, IT) and physicians and nurses of Orotta National referral Hospital in Asmara, Eritrea. The project was aimed at performing clinical assistance and training on the job to the local staff to improve the standard of care in the local Emergency Department. The duration of the project was initially planned to be 30 months, but unfortunately it was interrupted after 18 months because of lack of funds. The Italian staff was composed of two physicians and two nurses per period. To monitor local ICU activity, a retrospective survey of 36 months was performed. During the 36 months of data collection, 1169 patients were admitted to the ICU. Intra-ICU mortality rate resulted comparable before, during, and after Italian presence. On the contrary, the 28-day mortality resulted significantly lower bo th during and after the Italian stay. After project interruption, the Italian staff maintained contact with the Eritrean ICU personnel, who were invited to attend the Italian ICU for one month per year, and collected information about Orotta ICU activities.

关键词： Intensive Care Unit Developing Countries MEWS

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A novel solution treatment and aging for powder bed fusion-laser beam Ti-6Al-2Sn-4Zr-6Mo alloy:Microstructural and mechanical characterization

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 414-424页

作者： Gianluca Pirro Alessandra Martucci alessandro Morri Mariangela Lombardi Lorella Ceschini Department of Industrial Engineering(diN) Alma Mater Studiorum-University of BolognaBologna 40136Italy Department of Applied Science and Technology(diSAT) Politecnico di TorinoTorino TO 10129Italy

Ti-6Al-4Zr-2Sn-6Mo alloy is one of the most recent titanium alloys processed using powder bed fusion-laser beam(PBF-LB)*** alloy has the potential to replace Ti-6Al-4V in automotive and aerospace applications,given its superior mechanical properties,which are approximately 10%higher in terms of ultimate tensile strength(UTS)and yield strength after appropriate heat *** as-built conditions,the alloy is characterized by the presence of soft orthorhombicα″martensite,necessitating a postprocessing heat treatment to decompose this phase and enhance the mechanical properties of the ***,PBFed Ti6246 components undergo an annealing process that transforms theα″martensite into anα-βlamellar *** primary objective of this research was to develop a solution treatment and aging(STA)heat treatment tailored to the unique microstructure produced by the additive manufacturing process to achieve an ultrafine bilamellar microstructure reinforced by precipitation *** study investigated the effects of various solution temperatures in theα-βfield(ranging from 800 to 875℃),cooling media(air and water),and aging time to determine the optimal heat treatment parameters for achieving the desired bilamellar *** each heat treatment condition,differentα-βmicrostructures were found,varying in terms of theα/βratio and the size of the primaryα-phase *** attention was given to how these factors were influenced by increases in solution temperature and how microhardness correlated with the percentage of the metastableβphase present after *** tests were performed on samples subjected to the most promising heat treatment parameters.A comparison with literature data revealed that the optimized STA treatment enhanced hardness and UTS by13%and 23%,respectively,compared with those of the annealed *** surface analyses were conducted to investigate fracture mechanisms.

关键词： powder bed fusion-laser beam titanium alloys heat treatments mechanical properties fractographic analysis

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Exact Electronic Bands for a Periodic Pschl–Teller Potential

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Communications in Theoretical Physics 2016年第11期65卷 491-495页

作者： Francesco di filippo Canio Noce CNR-SPIN 1-84084 Fisciano(Salerno)Italy and Dipartimento di Fisica"E.R.Caianiello"Universit~di Salerno1-84084Fisciano(Salerno)Italy

We show that supersymmetry is a simple but powerful tool to exactly solve quantum mechanics problems. Here, the supersymmetric approach is used to analyse a quantum system with periodic Poschl-Teller potential, and to... 详细信息

关键词： supersymmetric quantum mechanics periodic Poschl-Teller potential SchrSdinger equation en-ergy bands

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Surgical complications after pancreatic transplantation:A computed tomography imaging pictorial review

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World Journal of Gastroenterology 2023年第46期29卷 6049-6059页

作者： Carlo D'alessandro Matteo Todisco Caterina di Bella filippo Crimì Lucrezia Furian Emilio Quaia Federica Vernuccio Department of Radiology University of PadovaPadova 35128Italy Department of Radiology 2 University Hospital of PadovaPadova 35128Italy Department of Surgical Kidney and Pancreas Transplantation UnitPadova 35128Italy Kidney and Pancreas Transplantation Unit University of PaduaPadova 35128Italy Department of Biomedicine Neuroscience and Advanced Diagnostics(BiND)University of PalermoPalermo 90127Italy Department of Radiology University Hospital of PadovaPadova 35128Italy

Pancreatic transplantation is considered by the American diabetes Association and the European Association for the Study of diabetes an acceptable surgical procedure in patients with type 1 diabetes also undergoing kidney transplantation in pre-final or end-stage renal disease if no contraindications are *** transplantation,however,is a complex surgical procedure and may lead to a range of postoperative complications that can significantly impact graft function and patient *** computed tomography(CT)is often adopted to evaluate perfusion of the transplanted pancreas,identify complications and as a guide for interventional radiology *** assessment after pancreatic transplantation should start with the evaluation of the arterial Y-graft,the venous anastomosis and the *** regard to complications,CT allows for the identification of vascular complications,such as thrombosis or stenosis of blood vessels supplying the graft,the detection of pancreatic fluid collections,including pseudocysts,abscesses,or leaks,the assessment of bowel complications(anastomotic leaks,ileus or obstruction),and the identification of *** aim of this pictorial review is to illustrate CT findings of surgical-related complications after pancreatic *** knowledge of surgical techniques is of key importance to understand postoperative anatomic changes and imaging ***,we first provide a short summary of the main techniques of pancreatic ***,we provide a practical imaging approach to pancreatic transplantation and its complications providing tips and tricks for the prompt imaging diagnosis on CT.

关键词： diabetes mellitus Type 1 Pancreas transplantation Complications Computed tomography diagnostic imaging

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Stability of Nonlinear differential-Algebraic Systems Via Additive Identity

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IEEE/CAA Journal of Automatica Sinica 2020年第4期7卷 929-941页

作者： Pierluigi di Franco Giordano Scarciotti alessandro Astolfi the Electrical and Electronic Engineering Department Imperial College LondonLondon SW72AZUK

The stability analysis for nonlinear differentialalgebraic systems is addressed using tools from classical control theory. Sufficient stability conditions relying on matrix inequalities are established via Lyapunov direct Method. In addition, a novel interpretation of differential-algebraic systems as feedback interconnection of a purely differential system and an algebraic system allows reducing the stability analysis to a smallgain-like condition. The study of stability properties for constrained mechanical systems, for a class of Lipschitz differential-algebraic systems and for an academic example is used to illustrate the theory.

关键词： differential-algebraic systems Lyapunov method small-gain theorem stability analysis

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Application of a Robust Model Reference Adaptive Control Algorithm to a Nonlinear Automotive Actuator

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International Journal of Automation and computing 2014年第4期11卷 377-391页

作者： alessandro di Gaeta Umberto Montanaro Istituto Motori National Research Council Naples Italy

Model reference adaptive control is a viable control method to impose the demanded dynamics on plants whose parameters are affected by large uncertainty. In this paper, we show by means of experiments that robust adaptive methods can effectively face nonlinearities that are common to many automotive electromechanical devices. We consider here, as a representative case study, the control of a strongly nonlinear automotive actuator. The experimental results confirm the effectiveness of the method to cope with unmodeled nonlinear terms and unknown parameters. In addition, the engineering performance indexes computed on experimental data clearly show that the robust adaptive strategy provides better performance compared with those given by a classical model-based control solution with fixed gains.

关键词： Model reference adaptive control robust adaptive control nonlinear systems automotive control electronic throttle body electromechanical actuators

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Comparison between the seismic response of 2D and 3D models of rigid blocks

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Earthquake Engineering and Engineering Vibration 2014年第1期13卷 151-162页

作者： Angelo di Egidio Daniele Zulli alessandro Contento Department of Civil Engineering Architecture and Environment(DICEAA)University of L'Aquila

A three-dimensional rigid body on the shape of a parallelepiped is modelled in order to rock on a side or a vertex of the base,in order to evaluate the seismic response of rigid blocks lying on a horizontal *** center of mass of the body is considered as eccentric with respect to its geometric *** seismic input,three Italian recorded accelerograms,with different spectral content,are *** study is mainly conducted to highlight the differences between the seismic response of 2D and 3D models of rigid blocks,with the aim to understand if,in some cases,the use of the 3D model of rigid block is required to obtain safer *** fact,the outcomes show that in some ranges of the geometrical and mechanical parameters that characterize the excitation and the body,a two-dimensional model,which is not able to consider the 3D rocking on a vertex,can provide unsafe *** particular,it is found that the overturning process of the three-dimensional block can occur under excitations which are lower than those which overturn a corresponding two-dimensional block.

关键词： seismic excitation 3D rigid block rectangular base rocking overturning

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Structural health monitoring of asphalt pavements using smart sensor networks: A comprehensive review

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Journal of Traffic and Transportation Engineering(English Edition) 2020年第5期7卷 639-651页

作者： alessandro di Graziano Vincenzo Marchetta Salvatore Cafiso Department of Civil Engineering and Architecture University of CataniaCatania 95225Italy

Early, effective and continuous monitoring allows to reduce costs and to extend life of road infrastructure. For this reason, over the years, more and more efforts have been made to implement more advanced and effective monitoring systems at ever more contained costs,going from impractical manual and destructive methods through automated in vehicle equipment to the most recent wireless sensor network(WSN) embedded into the pavement. The purpose of this paper is to provide a comprehensive, up-to-date critical literature review of wireless sensor networks for pavement health monitoring, considering, also,the experience gained for wired sensor as fundamental point of reference. This work presents both the methodology used to collect and analyse the current bibliography and provides a description and comments fundamental characteristics of wireless sensor networks for pavement monitoring for damage detection purposes, among which energy supply, the detection method, the hardware and network architecture and the performance validation procedures. A brief analysis of other possible complementary applications of smart sensor networks, such as traffic and surface condition monitoring, is provided. Finally, a comment is provided on the gaps and possible directions that future research could follow to allow the extensive use of wireless sensor networks for pavement health condition monitoring.

关键词： Pavement engineering Wireless sensor network Literature analysis Structural health monitoring Asphalt pavement

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Assessment of Cognitive skills via Human-robot Interaction and Cloud Computing

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Journal of Bionic Engineering 2019年第3期16卷 526-539页

作者： alessandro di Nuovo Simone Varrasi Alexandr Lucas Daniela Conti John McNamara alessandro Soranzo Sheffield Hallam University Sheffield S1 1WB United Kingdom IBM Hursley Lab Winchester SO21 2JN United Kingdom

Technological advances are increasing the range of applications for artificial intelligence, especially through its embodiment within humanoid robotics platforms. This promotes the development of novel systems for automated screening of neurological conditions to assist the clinical practitioners in the detection of early signs of mild cognitive impairments. This article presents the implementation and the experimental validation of the first robotic system for cognitive assessment, based on one of the most popular platforms for social robotics, Softbank "Pepper", which administers and records a set of multi-modal interactive tasks to engage the user cognitive abilities. The robot intelligence is programmed using the state-of-the-art IBM Watson AI Cloud services, which provide the necessary capabilities for improving the social interaction and scoring the tests. The system has been tested by healthy adults (N= 35) and we found a significant correlation between the automated scoring and one of the most widely used Paper-and-Pencil tests. We conclude that the system can be considered as a screening instrument for cognitive assessment.

关键词： socially assistive robotics brief cognitive testing human-robot interaction neurological screening cloud computing

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Finding a way to preserve mitochondria: new pathogenic pathways in experimental multiple sclerosis

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Neural Regeneration Research 2019年第1期14卷 77-78页

作者： Andrea Mancini Lorenzo Gaetani Lucia Gentili Massimiliano di filippo Clinica Neurologica Dipartimento di Medicina Università degli Studi di Perugia

Multiple sclerosis(MS)is a chronic disorder affecting central nervous system(CNS)in which inflammatory and neuro-degenerative features coexist since the earlier phases of the disease(Reich et al.,2018).During last years,attention has been directed toward the possible pathogenic pathways linking these two different features characterizing MS,in order to acquire a better understanding of the disease pathogenesis and to design new disease modifying *** available therapies for MS are primarily

关键词：小径病原硬化多重试验性线粒体保存疾病

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