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Resolutive Results with Oral Corticosteroids for Patients with COVID-19 in Pulmonary Inflammatory Phase. Successful Outpatient Experience during the Collapse of b.lem Do Para Health System—b.azil

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Health 2021年第8期13卷 830-838页

作者： Rob.rto S. Zeb.llos Luciana N. L. Cruz Vânia C. R. b.ilhante Adriana V. Lima Carlliane L. L. P. Martins Karla N. A. Lima Michele C. G. L. Leão b.linete L. Cruz alessandra b. dysarz Paulo C. b. Lob.to Erika S. Almeida Rute A. P. Costa Klevison C. Araújo Augusto C. C. Almeida Leônidas b. D. Junior Kathia O. Harada Rita H. V. S. Araújo Elaine X. Prestes Ivete M. S. Souza Avany M. P. Pereira Antônio b. M. A. Rocha Iracema A. Estevão Fagnei I. C. Carvalho Paulo M. P. Melo Clinical Care Sao Paulo Brazil Instituto de Ciencias da Saude Faculdade de Medicina Universidade Federal do Para Belem Brazil Fundacao Pub.ica Estadual Hospital de Clinicas Gaspar Vianna Belem Brazil Hospital da Policia Militar do Para Belem Brazil Imunoclinic Belem Brazil Universidade Estadual do Para Fundacao Santa Casa de Misericordia do Para Belem Brazil Clinica b.rros Cirurgia Plastica Belem Brazil Secretaria de Estado de Saude Pub.ica Castanhal Brazil Centro de Tratamento Oncologico Belem Brazil Sociedade b.asileira de Valorizaç ã o das Sociedades Medicas—SOb.MED S&#227 o Paulo Brazil Clinica de Nutrologia Sao Luiz Brazil Hospital Nipo b.asileiro de Olhos Belem Brazil Centro de Ciencias b.ologicas e da Saude Universidade do Estado do Para Belem Brazil Hospital Regional do b.ixo Amazonas Santarem Brazil Clinica Vallinoto Secretaria de Saude de b.rcarena Barcarena Brazil Estrategia Saude da Familia Secretaria Municipal de Saude de Ananindeua Centro Universitario do Estado do Para Belem Brazil A. M. P. Endocrinologia Belem Brazil Instituto Avertano Rocha Belem Brazil Departamento de Neurocirurgia Hospital Militar de Area De Sao Paulo Sao Paulo Brazil

In the face of new diseases, medicine needs to reinvent itself in order to contain and control epidemics, such as the one we have recently faced, COVID-19, a disease with a wide spectrum of clinical severity. A new moment has b.en estab.ished, since the application of well-known, effective and safe medications for other diseases, has shown high success rates in the treatment of COVID-19. Thereunto, studies with early intervention are needed, which can change the unfavorab.e outcome of patients. In this article, we report the successful experience using an oral strategy during the collapse of b.lem (Para, b.azil) Health System. Two hundred and ten patients were diagnosed with respiratory failure due to COVID-19, with no option of hospital treatment due to lack of b.ds and resources. These patients were then started on therapeutic regimen consisting of 40 mg prednisolone, 40 mg enoxaparin and macrolides (500 mg clarithromycin, 500 mg axetylcefuroxime) associated and followed in outpatient facilities. Two hundred and eight patients had an excellent therapeutic response and there were only two fatalities. These results push research b.undaries, valuing outpatient treatment with early use of prednisolone in the initial pulmonary phase, preventing severe COVID-19 pneumonitis. Adoption of the proposed treatment intends to reduce the need for hospitalization, as well as lethality, with social rob.st b.nefits and incalculab.e economic savings since involves the use of accessib.e, safe and not expensive medications.

关键词： COVID-19 Corticosteroids Pulmonary Inflammatory Phase Collapse b.azil

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