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New species in Aspergillus section Fumigati from reclamation sites in Wyoming (U.S.A.) and revision of A. viridinutans complex

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Fungal Diversity 2014年第1期64卷 253-274页

作者： alena nováková Vit Hubka Zuzana Dudová Tetsuhiro Matsuzawa alena Kubátová Takashi Yaguchi Miroslav Kolařík Biology Centre AS CR v.v.i.Institute of Soil BiologyNa Sádkách 737005ČeskéBudějoviceCzech Republic Laboratory of Physiology and Genetics of Fungi Institute of Microbiology AS CRv.v.iVídeňská108314220 Prague 4Czech Republic Department of Botany Faculty of ScienceCharles University in PragueBenátská212801 Prague 2Czech Republic Medical Mycology Research Center Chiba University1-8-1InohanaChuo-kuChiba 260-8673Japan

The Aspergillus viridinutans complex includes morphologically similar,soil-inhabiting *** its species boundaries have not been fully defined,many isolates from the complex have been isolated as opportunistic human and animal *** the present study,these species were dominant in spoil sites subjected to various types of reclamation management after coal *** species were characterised using two different PCR-fingerprinting methods,sequence data from the β-tubulin(benA)and calmodulin(caM)genes,macro-and micromorphology(optical and scanning electron microscopy),maximum growth temperatures and mating *** addition,RNA polymerase II gene(RPB2),actin(act1)and ITS sequences were deposited for the ex-type isolates of newly described *** mating experiment results,phylogenetic analyses and ascospore morphology suggested the presence of five species in the *** *** aureolus(*** aureola)was the only homothallic *** species,***,***(***)and *** ***.,were heterothallic and their morphologically distinguishable teleomorph was induced by systematic mating *** viridinutans *** to be a very rare species and was represented only by the ex-type isolate in which the MAT1-1 locus was *** viridinutans and *** were typified in accordance with the rules of the new botanical *** species outside the *** complex isolated from the reclamation sites were *** and *** as well as two new sister species,*** *** *** *** were closely related each to other and to *** new species are phylogenetically distant from all anamorphic species and resemble ***,*** and *** in micromorphology and are distinguishable from each other by the slower growth of *** on all tested ***,no isolate from the

关键词： Aspergillus fumigatus Heterothallic species MAT locus Neosartorya udagawae PCR fingerprinting Soil fungi

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Emerging potential of progranulin-dependent SorCS2 signaling in healthy and diseased nervous systems

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Neural Regeneration Research 2025年第9期20卷 2591-2593页

作者： alena Salasova Anders Nykjær Danish Research Institute of Translational Neuroscience DANDRITE-Nordic EMBL Partnership for Molecular Medicine and Centre of Excellence PROMEMODepartment of BiomedicineAarhus UniversityAarhusDenmark

The formation of the mammalian nervous system and its maturation into sensory,motor,cognitive,and behavioral circuits is a complex process that begins during early embryogenesis and lasts until young *** neurodevelopm... 详细信息

关键词： progr jointly CS2

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Behaviour of cranes(family Gruidae)mirrors their phylogenetic relationships

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Avian Research 2021年第3期12卷 285-295页

作者： Nela nováková Jan Robovský Faculty of Science University of South BohemiaBranišovská176037005ČeskéBudějoviceCzechia

Background:The behavioural repertoire of every species evolved over time and its evolution can be traced through the phylogenetic relationships in distinct ***(family Gruidae)represent a small,old,monophyletic group with well-corroborated phylogenetic relationships on the species level,and at the same time they exhibit a complex and well-described behavioural ***:We therefore investigated the evolution of behavioural traits of cranes in a phylogenetic context using several phylogenetic approaches and two types of trait *** cranes exhibit more than a hundred behavioural displays,almost one third of which may be phylogenetically ***:More than half of the analysed traits carry a significant phylogenetic *** ancestor of cranes already exhibited a quite complex behavioural repertoire,which remained unchanged in Balearicinae but altered greatly in Gruinae,specifically by the shedding of traits rather than their *** scoring has an influence on results within the Gruinae,primarily in genera Bugeranus and ***:Albeit the behavioural traits alone cannot be used for resolving species-level relationships within the Gruidae,when optimized on molecular tree,they can help us to detect interesting evolutionary transformations of behaviour repertoire within *** Limpkin(Aramus guarauna)seems to be the most enigmatic species and should be studied in detail for its behavioural repertoire,which may include some precursors of crane behavioural traits.

关键词： Ancestral behavioural repertoire Evolution Phylogenetic signal

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Crystal field and magnetism with Wannier functions: rare-earth doped aluminum garnets

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Journal of Rare Earths 2015年第12期33卷 1316-1323页

作者： Eva Mihóková Pavel novák Valentin V.Laguta Institute of Physics Czech Academy of Sciences

Using the recently developed method we calculated the crystal field parameters m yttrium anct lutetium aluminum garnets doped with seven trivalent Krarners rare-earth ions. We then inserted calculated parameters into the atomic-like Hamiltonian taking into account the electron-electron, spin-orbit and Zeeman interactions and determined the multiplet splitting by the crystal field as well as magnetic tensors. We compared calculated results with available experimental data. Very good agreement with the spectroscopic data and qualitative agreement with experimental tensors was found.

关键词： crystal field ab initio calculations gamets rare earths

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Advancing drug safety and mitigating health concerns:High-resolution mass spectrometry in the levothyroxine case study

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Journal of Pharmaceutical Analysis 2024年第9期14卷 1361-1371页

作者： Hana Chmelařová Maria Carmen Catapano Jean-Christophe Garrigues FrantišekŠvec Lucie nováková Department of Analytical Chemistry Faculty of Pharmacy in Hradec KrálovéCharles UniversityAkademika Heyrovského 120350005Hradec KrálovéCzech Republic Laboratoire SOFTMAT(IMRCP) Universitéde ToulouseCNRS UMR 5623UniversitéPaul Sabatier118 route de Narbonne31062 Toulouse Cedex 9France

Levothyroxine is a drug with a narrow therapeutic *** the drug formulation composition or switching between pharmaceutical brands can alter the bioavailability,which can result in major health ***,the increased adverse drug reactions have not been fully explained scientifically yet and a thorough investigation of the formulations is *** this study,we used a non-targeted analytical approach to examine the various levothyroxine formulations in detail and to reveal possible chemical ***-high-performance liquid chromatography coupled with a data-independent acquisition high-resolution mass spectrometry(UHPLC-DIA-HRMS)was ***-DIA-HRMS allowed not only the detection of levothyroxine degradation products,but also the presence of non-expected components in the *** these,we identified compounds resulting from reactions between mannitol and other excipients,such as citric acid,stearate,and palmitate,or from reactions between an excipient and an active pharmaceutical ingredient,such as levothyroxine-lactose *** addition to these compounds,undeclared phospholipids were also found in three *** non-targeted approach is not common in pharmaceutical quality control *** the presence of unexpected compounds in drug formulations proved that the current control mechanisms do not have to cover the full complexity of pharmaceutical formulations necessarily.

关键词： Levothyroxine Excipients Impurities UHPLC-DIA-HRMS Drug safety

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Role of forests in headwater control with changing environment and society

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International Soil and Water Conservation Research 2021年第1期9卷 143-157页

作者： Josef Krecek Jana nováková Ladislav Palán Eva Pazourková Evzen Stuchlík Department of Hydrology Czech Technical University in PragueThákurova 7CZ-16629Prague 6Czech Republic Independent Botanist Na Vrcholu 4CZ-13000PragueCzech Republic AON Impact Forecasting Václavskénáměstí19CZ-11000PragueCzech Republic Institute of Hydrobiology Biology CentreCzech Academy of SciencesNa Sádkách 7CZ-37005(C)eskéBudějoviceCzech Republic

Forest practices in headwater catchments are related to environmental and social *** aim of this study is to analyse the changing protective functions of forests in the upper plain of the Jizera Mts.(North Bohemia,Czech Republic)since the second half of the 19th *** time,forests have gradually changed from native stands to spruce plantations(Picea abies),introducing exotic conifers(more resistant to air pollution),and,recently,back to more diverse mixed *** priority in pro-tective forest functions there shifted from flood protection to integrated control of water resources(quantity and quality).In the 1980s,forest-water interactions were degraded by consequences of extreme acid atmospheric deposition,forest die-back,and extensive *** the Jizerka catchment,first signs of recovery were observed in the early *** waters there are still affected by prolonged *** reconstruction of stream water chemistry at Jizerka follows the drop of the acid deposition in some 5 years,the revival of stream biota takes 10-15 *** 2071-2100,the pro-jected climate change shows rising annual air temperatures by 3.0-4.6℃,decreasing water yield by 65-123 mm,60%drop in'minimum residual discharge',and 20-30%rise in ***,these projected environmental changes cannot substantially decline the high potential in water resource recharge,or,start reverse processes in recent recovery from acidification and radically affect the exis-tence of planned mixed forests in the upper plain of the Jizera Mts.

关键词： Headwater catchment Forest functions Water resource recharge Acid atmospheric deposition Climate change

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Morphological characteristics of blood cells in monitor lizards:is erythrocyte size linked to actual body size?

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Integrative Zoology 2013年第1期8卷 39-45页

作者： Petra FRÝDLOVÁ Jan HNÍZDO Lenka CHYLÍkovÁ OlgaŠIMkovÁ Veronika CIKÁnovÁ Petr VELENSKÝ Daniel FRYNTA Department of Zoology Charles University in PraguePragueCzech Republic Animal Clinic PragueCzech Republic Prague Zoo PragueCzech Republic

Blood cell morphology and count are not uniform across ***,between-species comparisons revealed that the size of red blood cells is associated with body size in some lizard taxa,and this finding was interpreted in the context of the metabolic *** the present study,we examined the numbers and the size of blood cells in 2 species of monitor lizards,the mangrove-dwelling monitor(Varanus indicus)and the savannah monitor(***),and we compared these traits in individuals of different body *** results revealed that during the course of ontogeny,the size of red blood cells increases with body *** the mass-specific metabolic rate decreases with body size and the cell volume-to-surface ratio decreases with the cell size,changes in the erythrocyte size might be the result of oxygen transport adjustment.

关键词： blood parameters body size erythrocyte size metabolic theory Varanidae

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Regulated upon activation,normal T cell expressed and secreted(RANTES)levels in the peripheral blood of patients with Alzheimer’s disease

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Neural Regeneration Research 2021年第4期16卷 775-779页

作者： Gabriela Vacínová Daniela Vejražkova Robert Rusina Iva Holmerová Hana Vaňková Eva Jarolímová Josef Včelák Běla Bendlová Markéta Vaňková Department of Molecular Endocrinology Institute of EndocrinologyPragueCzech Republic Department of Anthropology and Human Genetics Faculty of ScienceCharles UniversityPragueCzech Republic Department of Neurology Third Faculty of Medicine of Charles University and Thomayer Hospital PragueCzech Republic II.Internal Medicine Clinic Third Faculty of MedicineCharles UniversityPragueCzech Republic Faculty of Humanitites Charles University PragueCzech Republic

Alzheimer’s disease(AD)is the most common type of dementia,but it is very difficult to diagnose with certainty,so many AD studies have attempted to find early and relevant diagnostic *** upon activation,normal T cell expressed and secreted(RANTES,also known as C-C chemokine ligand)is a chemokine involved in the migration of T cells and other lymphoid *** in RANTES levels and its expression in blood or in cerebrospinal fluid have been reported in some neurodegenerative diseases,such as Parkinson’s disease and multiple sclerosis,but also in metabolic diseases in which inflammation plays a *** aim of this observational study was to assess RANTES levels in peripheral blood as clinical indicators of *** levels of RANTES were investigated in 85 AD patients in a relatively early phase of AD(median 8.5 months after diagnosis;39 men and 46 women;average age 75.7 years),and in 78 control subjects(24 men and 54 women;average age 66 years).We found much higher plasma levels of RANTES in AD patients compared to controls.A negative correlation of RANTES levels with age,disease duration,Fazekas scale score,and the medial temporal lobe atrophy(MTA)score(Scheltens’s scale)was found in AD patients,i.e.,the higher levels corresponded to earlier stages of the *** RANTES levels were not correlated with cognitive *** AD patients,RANTES levels were positively correlated with the levels of pro-inflammatory cytokines interleukin-6 and tumor necrosis factor-α,which is consistent with the wellknown fact that AD is associated with inflammatory *** levels were also positively correlated with insulin levels in AD patients,with insulin resistance(HOMA-R)and pancreatic beta cell function(HOMA-F).This study evaluated several clinical and metabolic factors that may affect plasma levels of RANTES,but these factors could not explain the increases in RANTES levels observed in AD *** levels of RANTES appear to be an interesting

关键词： Alzheimer’s disease biomarker central nervous system cognitive impairment inflammation RANTES

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Quantitative evaluation of LAL productivity of colloidal nanomaterials:Which laser pulse width is more productive,ergonomic,and economic?

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Chinese Physics B 2022年第7期31卷 23-33页

作者： alena Nastulyavichus Nikita Smirnov Sergey Kudryashov P.N.Lebedev Physical Institute of the Russian Academy of Sciences MoscowRussia

Near-IR(wavelength≈1μm)laser ablation of bulk,chemically-inert gold in water was compared for different laser pulse width in broad the range of 300 fs–100 ns,comparing a number of key ablation characteristics:mass loss,singleshot crater volume and extinction coefficient of the generated colloidal solutions taken in the spectral ranges of interband transitions and localized plasmon *** to related air-based ablation results,at the given fluences laser ablation in the liquid resulted in the maximum ablation yield per unit energy and maximum NP yield per pulse and per unit energy for the picosecond lasers,occurring at subcritical peak pulse powers for laser *** self-focusing effect was demonstrated to yield in incomplete,effectively weaker focusing in the water filaments of ultrashort laser pulses with supercritical peak powers,comparing to linear(geometrical)focusing at sub-critical peak *** the other,nanosecondpulse extreme the high ablation yield per pulse,but low ablation yield per unit energy and low NP yield per pulse and per unit energy were related to strong ablation plasma screening,providing mass removal according to the well-established scaling relationships for *** comparison of the ablation and nanoparticle generation efficiency versus the broad fs–ns laser pulse width range was enabled in terms of productivity,economicity,and ergonomicity,using the proposed universal quantitative criteria.

关键词： laser ablation of gold in liquid ablated mass critical power for self-focusing filamentation

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多壁纳米碳管对磷酸铁锂正极材料热稳定性及表面形貌的影响(英文)

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新型炭材料 2013年第1期28卷 1-7页

作者： Mária Filkusová Andrea Fedorková Renáta Oriňáková Andrej Oriňák Zuzana nováková Lenka Skantárová Department of Physical and Theoretical Chemistry Faculty of Science Comenius University Mlynská|Dolina SK-842 15 Bratislava 4 Slovak Republic Department of Physical Chemistry Faculty of Science P.J. afárik University Moyzesova 11 SK-04154 Koice Slovak Republic Department of Electrical and Electronic Technology Faculty of Electrical Engineering and Communication Brno University of Technology Czech Republic Department of Analytical Chemistry Faculty of Science Comenius University Mlynská|Dolina SK-842 15 Bratislava 4 Slovak Republic

合成了一种新型的LiFePO4/多壁纳米碳管(MWCNTs)复合正极材料。通过MWCNTs和PPy-PEG粘结剂有机地在LiFePO4颗粒间构成三维网络导电结构,并借助SEM、TGA和高分辨裂解气相色谱,研究了LiFePO4-MWCNT正极材料的表面形貌和热稳定性。结果表明... 详细信息

合成了一种新型的LiFePO4/多壁纳米碳管(MWCNTs)复合正极材料。通过MWCNTs和PPy-PEG粘结剂有机地在LiFePO4颗粒间构成三维网络导电结构,并借助SEM、TGA和高分辨裂解气相色谱,研究了LiFePO4-MWCNT正极材料的表面形貌和热稳定性。结果表明,500℃下该材料的热分解程度非常小,说明MWCNTs和PPy-PEG的复合是提高LiFePO4正极材料的热稳定性和改善表面形貌的有效途径。

关键词：多壁纳米碳管多吡咯磷酸铁锂锂离子电池

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