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Changes in the Rate of Human Papilloma Virus Serotypes after Vaccine Implementation: A Descriptive Study

Open Journal of Obstetrics and Gynecology 2023年第5期13卷 934-949页

作者： Ana María Colino Gallardo Montserrat de la Torre Serrano Lone Nielsen alejandro Pascual Martín Concepción Millana de Ynes María Jesús González Fuensalida Patricia Barreiro Sanabria Eva Rodríguez Escudero Dolores García López Aranzazu Gómez Rodríguez Rosa Rodero Villanueva María Jesús Fernández Aceñero Department of Surgical Pathology Hospital Clínico San Carlos Madrid Spain Department of Surgical Pathology Hospital Universitario del Sureste Madrid Spain Grupo de Investigación en Anatomía Patológica Hospital Clínico San Carlos IdISSC Madrid Spain Department of Legal Medicine Psychiatry and Surgical Pathology Complutense University of Madrid Madrid Spain

Background: The main objective of this study is to describe the rate of the different serotypes of HPV in cervical cytologies and biopsies in three different periods: 2002-2006 (prior to the implementation of the vaccination programs in Spain), 2009-2011 (shortly after this implementation) and 2020 (almost 15 years after introduction of the vaccine) at a single hospital. Methods: This is an observational, descriptive, retrospective study based on the review of the results of the determination of the HPV serotype using the commercial kit (Genomica®;PharmaMar LTD) in cervical liquid-based cytologies and biopsies at a single large tertiary hospital, Hospital Clínico San Carlos, in Madrid, Spain. We have collected the data from three different time periods: 2002-2006;2009-2011, and 2020 to try to understand the potential changes associated with the use of the vaccine. Results: In these time periods we have reviewed the data from 1420 women. In the three periods the most frequent serotype was HPV 16, followed by HPV 18 or a combination of both. The most frequent low risk serotype was HPV 6 followed by the combination of HPV 6 and 11. It has been verified in our study that the prevalence of the category “others”, constituted by the three risk groups, has undergone a progressive increase, beginning with an infection rate of 65.43% in 2002-2006 to finally rise up to 90.92% in the year 2020. Conclusions: Our study reveals an increase in the number of infections by the HPV serotypes that are not included in the tetravalent vaccine.

关键词： HPV Serotypes Cervix Vaccine Women’s Health

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Case Series of 11 Patients Operated with Axial-LIF Technique in a Single Center in Mexico

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Open Journal of Modern Neurosurgery 2023年第3期13卷 129-136页

作者： Alfonso Vega Sosa Sergio Ivan Reyna Heredia Apolinar De la Luz Laguna Ivanka Berenice Moreno Villa Marlene de la Peña Gutiérrez Ramiro López Elizalde Cuauhtémoc Gil Ortiz Andres Jaime Aguirre Ivan alejandro Mendez Guerrero Edwin Rolando Sanchez Vallejo Alejandra Grisel Mendoza Zuñiga Ricardo Cazares Mejía Carlos Erosa Velázquez Universidad Nacional Autónoma de México Mexico City Mexico Centro Medico Nacional 20 de Noviembre Mexico City Mexico Centro Médico Naval Mexico City Mexico

Introduction: Since the earliest description of spinal fusion in 1911 and later by Dr. Fred H. Albee, it has become one of the most commonly performed procedures by orthopedist and neurosurgeons. The spinal fusion is now used to treat a variety of indications, such as traumatic injuries, deformities, primary and secondary tumors, infections and degenerative conditions of the spine. The risk of iatrogenic injury during traditional anterior, posterior, and transforaminal open fusion surgery is significant. The axial lumbar interbody fusion (Axia-LIF) is a minimal invasive technique which uses the retroperitoneumpresacral anatomical corridor to fuse the lumbar vertebral bodies L4-L5-S1 avoiding manipulation of the annular ligament, paravertebral muscles and facet joints. Methods: In this retrospective series, we report all the cases made in the Centro Medico Naval in México City in two years. A total of eleven patients with degenerative disc disease and spondylolisthesis underwent Axia-LIF one or two level systems with a 36 months clinical and radiographic follow-up. The outcomes included Oswestry Disability Index (ODI) score and leg/back pain severity. Radiographic outcome was evaluated with dynamics and orthogonal x-ray, as well as lumbosacral tomography scan to evaluate fusion status. Results: Nine patients underwent Axia-LIF one level system (L5-S1) and the rest two levels system (L4-S1). Ten patients were fixated with transpedicular percutaneous screws and one with facets joints screws. No intraoperative complications were reported. The mean back pain severity improved 57% in 12 months, and the mean leg pain severity improved 50% in the same time (P < 0.001). Mean ODI scores improved 58%, from 60% ± 16% at baseline to 25% ± 8% at twelve months (P < 0.001). At one year, a patient developed pseudoarthrosis that required posterolateral arthrodesis with transpedicular percutaneous screws. At 36 months monitoring, 100% patients presented a total interbody fusion in the

关键词： Spine Surgery Axial-LIF Procedure Axial-LIF CMN 20 de Noviembre Spinal Fusion Centro Médico Naval

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材料的“裸露”

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现代装饰 2017年第3期 92-99页

作者： alejandro Ruiz Chialing Chang 庄愉佐藤仁美 Adnen Rovero Quentin de Coster Zaha Hadid Architects Atelier F Ceramics Hyfen Saerom Yoon Sebastian Herkner Serena Confalonieri 彭佳 Benwu Studio Nude Designs

在我国的传统艺术中,有一种重要的表现手法——“白描”,被广泛运用在了文学和绘画之中。在文学创作中,“白描”即指用最简练节省的笔墨、不重修饰与渲染,勾勒出鲜明生动的人物形象;在绘画中,“白描”就是完全用线条来表现物象,画风朴... 详细信息

在我国的传统艺术中,有一种重要的表现手法——“白描”,被广泛运用在了文学和绘画之中。在文学创作中,“白描”即指用最简练节省的笔墨、不重修饰与渲染,勾勒出鲜明生动的人物形象;在绘画中,“白描”就是完全用线条来表现物象,画风朴素简洁、注重质感,不求精雕细刻,只求以“形”传“神”。鲁迅曾说,“白描却没有秘诀。如果要说有,也不过是和障眼法反一调：有真意,去粉饰,少做作,勿卖弄而已。”

关键词：文学创作人物形象 tradition 杯托颜色组合晕染纯音乐清透三件套伦敦奥运会

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社会的冠状神经元

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城市建筑 2015年第13期12卷 102-102页

作者： alejandro Martín Torrente 李媛

我最近读到一篇文章说科学家已经发现心脏有自己的神经系统,心脏向大脑传递的信息比从大脑获取的信息多,它甚至能控制大脑某些区域的活动。当我读到这篇文章的时候,Santiago Cirugeda浮现在我的脑海,这则新闻从科学的角度证明了他的能... 详细信息

我最近读到一篇文章说科学家已经发现心脏有自己的神经系统,心脏向大脑传递的信息比从大脑获取的信息多,它甚至能控制大脑某些区域的活动。当我读到这篇文章的时候,Santiago Cirugeda浮现在我的脑海,这则新闻从科学的角度证明了他的能力。没错,Santiago Cirugeda是极少数拥有超能力的人之一,是拥有更多特殊细胞的人之一,也是极少数能够以一种非常自然的方式做出选择的人之一。

关键词： Santiago 超能力 surveying chance 室内陈设建筑师事务所 carrying everything 模型制作建筑事务所

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降低管道摩擦力的聚合物添加剂

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化学工程 1984年第3期 96-96页

作者： alejandro Anaya Durand ,曹淦坤天津卫津化工厂

尽管加入很少的某些高分子量聚合物,但是却能降低液体的摩擦力系数。这种效应通常称为Toms现象,由于它能够节省不断上涨的泵的能耗价值而变得更加令人重视. 图1以水中加入聚氧化乙烯树脂（OCH2CH2）x为例,表示了摩擦力降低百分数与聚合... 详细信息

尽管加入很少的某些高分子量聚合物,但是却能降低液体的摩擦力系数。这种效应通常称为Toms现象,由于它能够节省不断上涨的泵的能耗价值而变得更加令人重视. 图1以水中加入聚氧化乙烯树脂（OCH2CH2）x为例,表示了摩擦力降低百分数与聚合物浓度的关系。这种树脂分子量在500,000以上,是由长链分子构成。其摩

关键词：聚合物大分子化合物摩擦力非保守力添加剂

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减少向环境中释放抗生素和抗生素耐药基因的管理措施

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环境与职业医学 2014年第1期31卷 72-77页

作者： Amy Pruden D.G.Joakim Larsson alejandro Amézquita Peter Collignon Kristian K.Brandt David W.Graham James M.Lazorchak Satoru Suzuki Peter Silley Jason R.Snape Edward Topp Tong Zhang Yong-Guan Zhu 何蓉汪源张伊人金泰廙 Department of Civil and Environmental Engineering Virginia TechBlacksburgVirginiaUSA Institute for Biomedicine The Sahlgrenska AcademyUniversity of GothenburgGothenburgSweden Unilever-Safety & Environmental Assurance Centre SharnbrookUnited Kingdom Australian National University CanberraAustralia Canberra Hospital CanberraAustralia Department of Plant and Environmental Sciences University of CopenhagenFrederiksbergDenmark School of Civil Engineering and Geosciences Newcastle UniversityNewcastle upon TyneUnited Kingdom Office of Research and Development U.S. Environmental Protection AgencyCincinnatiOhioUSA Center for Marine Environmental Studies Ehime UniversityMatsuyamaEhimeJapan MB Consult Limited SouthamptonUnited Kingdom University of Bradford BradfordUnited Kingdom AstraZeneca Brixham Environmental LaboratoryBrixhamUnited Kingdom Agriculture and Agri-Food Canada LondonOntarioCanada Department of Civil Engineering University of Hong Kong Key Laboratory of Urban Environment and Health Institute of Urban EnvironmentChinese Academy of Sciences

[背景]全球越来越关注污染土壤、水环境对抗生素耐药性产生和蔓延的作用。[目的]本研究的目的是确定那些可以减少抗生素和抗生素耐药性经环境途径传播影响因素的管理措施,以最终达到延长抗生素使用寿命的目标。此外还研究了实施这些措... 详细信息

[背景]全球越来越关注污染土壤、水环境对抗生素耐药性产生和蔓延的作用。[目的]本研究的目的是确定那些可以减少抗生素和抗生素耐药性经环境途径传播影响因素的管理措施,以最终达到延长抗生素使用寿命的目标。此外还研究了实施这些措施的激励和阻碍因素。[方法]着重研究有关农业源头限制,生活、医院和工业废水处理,以及水产养殖三方面的管理措施。[讨论]我们确定了若干措施,如养份管理、径流控制和基础设施升级。凡适当处,可提供世界不同地区的典型实例。研究还强调了监测和验证管理策略有效性的重要性。最后,介绍了一则瑞典的案例研究,展示了通过沟通来发动利益相关方参与和促进行动的重要作用。[结论]在许多情况下,可以花费很少或根本不花费成本来减少抗生素和抗生素耐药性细菌的环境释放。一些管理措施与现有的政策和目标协同作用。预期的效益是延长现有和未来的抗生素使用寿命。虽然往往难以量化所降低的风险,但是全球抗生素耐药性相关发病率和死亡率加速增长,这一情况的严重程度强烈表明采取行动的必要性。

关键词：农业抗生素制造抗生素耐药性水产养殖畜牧粪便管理政策废水处理

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新加坡UOL Edge画廊

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设计家 2012年第4期 90-93页

作者： Colin Seah Tulsi Grover Joyce Low Angie Ng Anita Shewchuk Ron Sim David Tan Marcin Skolimowski Noel Banta Aliza Suarez Lolleth alejandro Allan Veloso Pauline Pan Ministry of Design MOD

近年来,新加坡正在经历一场住宅公寓开发的热潮。因此,建筑师一直呼吁设计一个临时性的展示建筑,用来展示这些建筑,并促进其出售。很多展示空间的设计显然并不能引发丰富的想象,反而呈现出一种程式化的相似——与建筑表皮完全无关的笨... 详细信息

近年来,新加坡正在经历一场住宅公寓开发的热潮。因此,建筑师一直呼吁设计一个临时性的展示建筑,用来展示这些建筑,并促进其出售。很多展示空间的设计显然并不能引发丰富的想象,反而呈现出一种程式化的相似——与建筑表皮完全无关的笨拙、匀称的立方体玻璃、石膏、木材与室内设计的表现形式,典型的毫无节制的奢华和一成不变的排场。顺应这一潮流,MOD设计的这座画廊探讨并重新定义了象征新加坡公共管理能力的展示空间的类型。

关键词：新加坡 Edge 画廊室内设计展示空间建筑师建筑表皮管理能力

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Sperm Quality in Holstein Bulls Friesian and Brahmans of Frozen Semen Commercially

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Open Journal of Animal Sciences 2015年第3期5卷 229-231页

作者： alejandro Córdova-Izquierdo Gustavo Ruiz-Lang Román Espinosa-Cervantes Adrían Emmanuel Iglesias-Reyes Maximino Méndez-Mendoza Rubén Huerta-Crispín Abel Edmundo Villa-Mancera Ma. De Lourdes Juárez-Mosqueda Pedro Sánchez-Aparicio Jaime Olivares-Pérez Juan Eulogio Guerra-Liera Gerardo Cansino-Arroyo Departamento de Producción Agrícola y Animal Universidad Autónoma Metropolitana Unidad Xochimilco México D.F. México Facultad de Veterinaria Benemérita Universidad Autónoma de Puebla Puebla México Departamento de Morfología FMVZ-UNAM México D.F. México Facultad de Veterinaria Universidad Autónoma del Estado de México Toluca México Unidad Académica de Medicina Veterinaria y Zootecnia Universidad Autónoma de Guerrero Guerrero México Facultad de Agronomía Universidad Autónoma de Sinaloa Culiacán México División Académica de Ciencias Agropecuarias Universidad Juárez Autónoma de Tabasco Villahermosa México

The aim of this study was to assess sperm quality (motility, viability and acrosomal integrity) sperm from commercially frozen semen straws two breeds of bulls Bos taurus (holstein Frisian) and Bos indicus (Brahman). 9 commercial straws 0.5 ml of Holstein bull semen and 9 Brahman bull were thawed, they were kept for two hours at room temperature and motility, viability and acrosomal integrity (NAR) was assessed. The results were 30% motility, viability 40% and 30% of NAR in the Holstein breed. Brahma race for motility 40%, 50% and 40% viability was obtained NAR. In conclusion, according to the results of the variables analyzed, the Brahman breed in sperm quality was better than the Holstein breed;however, the results of both races meet minimum standards of quality sperm for use in artificial insemination (AI) field level.

关键词： Semen Thawed Bulls Frozen Semen Sperm Quality

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Depressive severity associated with cesarean section in young depressed individuals

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Chinese Medical Journal 2019年第15期132卷 1883-1884页

作者： Xiao-Tong Yang Wen-Rui Zhang Zi-Chen Tian Kun Wang Wei-Jun Ding Yuan Liu Chun-Xiu Wang Hai-Xia Leng Mao Peng Wen-Feng Zhao Jia-Yi Li Lei Yang Xing-Yue Zhang Lei Wu Jun-Hui Wang alejandro Fernandez Tian-Mei Si Liu-Hui Fu Jean-Eric Ghia Hui-Qing Dong Yu-Ping Wang Hong-Xing Wang Department of Neurology Xuanwu Hospital Capital Medical University Beijing 100053 China Department of Immunology University of Manitoba Winnipeg Manitoba R3E 0T5 Canada Carleton College One North College Street Northfield MN 55057 USA Department of Neurology Beijing Puren Hospital Beijing 100062 China Department of Evidence-Based Medicine Xuanwu Hospital Capital Medical University Beijing 100053 China The First Clinic Medical School Capital Medical University Beijing 100053 China The Lunenfeld-Tanenbaum Research Institute Mount Sinai Hospital Toronto Ontario M5G 1×5 CanadaTranslational Research Program University of Toronto Toronto Ontario M5S 1A1 Canada Translational Research Program University of Toronto Toronto Ontario M5S 1A1 Canada Peking University Sixth Hospital Beijing 100083 China Institute of Immunology Tsinghua University School of Medicine Beijing 100084 China

This cross-sectional study recruited consecutively 347 patients (178 males,169 females) aged 19 to 30 years with a diagnosis of MDD according to Diagnostic and Statistical Manual of Mental Disorders,Fifth Edition (DSM-V) criteria who underwent in-person interviews,the mini international neuropsychiatric interview,and physical examinations by experienced psychiatrists at Division of Neuropsychiatry,Department of Neurology,Xuanwu Hospital of Capital Medical University (Beijing,China) between August 20,2015,and December 28,*** patients were excluded with anemia,thyroid dysfunction,mental retardation,neurologic conditions,bipolar disorders,schizophrenia,and other mental *** symptoms were assessed with the Hamilton rating scale for depression (HAMD-17) by three experienced psychological testing technicians who were blinded to all subjects' birth delivery types at the Neuropsychological Center of Department of Neurology of Xuanwu *** study was conducted in accordance with the Declaration of Helsinki and was approved by the Ethics Committee of Xuanwu *** a retrospective study and data analysis were performed anonymously,this study was exempt from the informed consent from patients.

关键词： cesarean section depressed individuals

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Development of a Construction Material for Indoor and Outdoor, Metakaolinite-Based Geopolymer, with Environmental Properties

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材料科学与工程（中英文A版） 2019年第4期9卷 131-142页

作者： M.Mondragón-Figueroa Héctor.R.Guzmán-Carrillo MiguelÁngel Rico JoséLuis.Reyez-Araiza Jorge.Pineda-Piñón Edgar J.López-Naranjo María C.Columba-Palomares Jóse.M.López-Romero Josè.Ramón Gasca-Tirado alejandro.Manzano-Ramírez CINVESTAV-Querétaro Libramiento Norponiente#2000Fraccionamiento Real de JuriquillaQuerétaro 76230Qro.México Facultad de Química Universidad Autónoma de Querétaro centro de estudios Académicos sobre contaminación AmbientalQuerétaro 76010Qro.México DIPFI Facultad de IngenieríaUniversidad Autónoma de QuerétaroC.U.Cerro de las CampanasCentroQuerétaro 76010Qro.México Instituto Politécnico Nacional Centro de Investigación en Ciencia Aplicada y Tecnología AvanzadaUnidad QuerétaroCerro Blanco No.141Colinas del CimatarioQuerétaro76090Qro.México DIP-CUCEI Universidad de GuadalajaraJoséGuadalupe Zuno#48Los BelenesZapopan 45100Jal.México Facultad de Farmacia Universidad Autónoma del Estado de MorelosAv.Universidad#1001Cuernavaca 62209Mor.México Departamento de Ingeniería Universidad de GuanajuatoGuanajuato 36000México

Environmental problems that came from the human activity have many facets,since pollution of the atmosphere arises from vehicles,industrial emissions while pollution of water could be from organic compounds,pesticides *** can cause serious health effects,such as respiratory diseases,including asthma and lung ***,in the present work,a kinetic study on the effective adsorption and photo degradation of methylene blue(MB)dye,under ultraviolet A(UVA)irradiation of an alkali activated inorganic polymer(geopolymer)with homogeneously dispersed titanium dioxide(TiO2)micro-particles is *** addition,antimicrobial testing of the alkali activated TiO2 material was performed showing a bacteriostatic effect.

关键词： Heterogeneous photocatalysis semiconductor alkali activated bacteriostatic effect

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