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Plyometric exercise and bone health in children and adolescents: a systematic review

World Journal of Pediatrics 2017年第2期13卷 112-121页

作者： alejandro gómez-bruton (A)ngel Matute-Llorente alejandro gonzález-Agüero JoséA.Casajús germán Vicente-Rodríguez growth ExerciseNutrition and Development(GENUD)Research GroupUniversity of ZaragozaZaragozaSpain Faculty of Health and Sport Sciences(FCSD) Department of Physiatry and NursingUniversity of ZaragozaRonda Misericordia 522001-HuescaSpain growth ExerciseNutrition and Development(GENUD)Research GroupUniversity of ZaragozaZaragozaSpain

Background:Many jumping interventions have been performed in children and adolescents in order to improve bone-related variables and thus,ensure a healthy bone development during these periods and later in *** systematic review aims to summarize and update present knowledge regarding the effects that jumping interventions may have on bone mass,structure and metabolism in order to ascertain the efficacy and durability (duration of the effects caused by the intervention) of the *** sources:Identification of studies was performed by searching in the database MEDLINE/PubMed and *** studies were identified by contacting clinical experts and searching bibliographies and *** terms included 'bone and bones','jump*','weight-bearing','resistance training' and 'school intervention'.The search was conducted up to October *** studies that had performed a specific jumping intervention in under 18-year olds and had measured bone mass were *** extraction of articles was done by 2 authors using predefined data ***:A total of 26 studies were included in this ***-four studies found positive results as subjects included in the intervention groups showed higher bone mineral density,bone mineral content and bone structure improvements than *** two studies found no effects on bone mass after a 10-week and 9-month ***,those studies that evaluated the durability of the effects found that some of the increases in the intervention groups were maintained after several ***:Jumping interventions during childhood and adolescence improve bone mineral content,density and structural properties without side *** type of interventions should be therefore implemented when possible in order to increase bone mass in early stages of life,which may have a direct preventive effect on bone diseases like osteoporosis later in fife.

关键词： adolescents bone mineral density intervention jumping osteoporosis

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Amyloid-beta pathology-induced nanoscale synaptic disruption:the case of the gABA_B-gIRK assembly

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Neural Regeneration Research 2025年第5期20卷 1409-1410页

作者： Rafael Lujan alejandro Martín-Belmonte Sergi Ferré Francisco Ciruela Synaptic Structure Laboratory Instituto de Biomedicina de la UCLM(IB-UCLM)Departamento de Ciencias MédicasInstituto de Investigación en Salud de Castilla-La Mancha(IDISCAM)Facultad de MedicinaUniversidad Castilla-La ManchaCampus BiosanitarioC/AlmansaAlbaceteSpain Integrative Neurobiology Section National Institute on Drug AbuseIntramural Research ProgramNational Institutes of HealthBaltimoreMDUSA Pharmacology Unit Department of Pathology and Experimental TherapeuticsSchool of Medicine and Health SciencesInstitute of NeurosciencesUniversity of BarcelonaNeuropharmacology&Pain GroupNeuroscience ProgramBellvitge Institute for Biomedical ResearchL’Hospitalet de LlobregatSpain

Alzheimer's disease (AD) is characterized by an imbalance between excitatory and inhibitory brain networks,leading to aberrant homeostatic synaptic *** has progressively been recognized as syna ptopathy and syna ptic dysfunction has been identified as a key component of its pathogenesis (Schirinzi et al.,2020).Syna ptic dysfunction is believed to precede synapse loss,a primary biological correlate of cognitive decline in AD,inevita bly associated with neuronal death.

关键词： Alzheimer pathology

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Dinophysoid dinoflagellates from subphotic depths:Amphisolenia ***,Dinofurcula tricornuta ***.,and Dinophysis profunda ***.(Dinophysales,Dinophyceae)

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Journal of Oceanology and Limnology 2022年第2期40卷 703-711页

作者： Fernando gÓmez Department of Biological and Environmental Sciences and Technologies University of SalentoLecce 73100Italy

Three species of dinophysoid planktonic dinoflagellates are described from the eastern Mediterranean *** *** was collected at 70-m depth in the Ionian *** small species showed a more asymmetric midbody and a proportionally longer neck when compared to the closer relative *** individuals of Dinofurcula tricornuta *** at 154-m depth in the Marmara Sea are characterized by three posterior-oriented processes when compared to its congeneric *** is the first record of the genus Dinofurcula beyond the eastern tropical Pacific *** profunda *** at 500-m depth in the Ionian Sea is characterized by ovate hypotheca and a serrate crest-like left sulcal list when compared to its close relative *** findings evidence an undescribed biodiversity in the under-sampled subphotic depths.

关键词： deep ocean Dinophyta Dinoflagellata Mediterranean Sea mesopelagic new species

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Morphology and distribution of Pronoctiluca (Dinoflagellata, incertae sedis) in the Pacific Ocean

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Acta Oceanologica Sinica 2013年第4期32卷 71-76页

作者： gómez Fernando Department of Biological Oceanography Institute of Oceanography University of S o Paulo

The diversity and distribution of Pronoctiluca, a marine dinoflagellate of enigmatic systematic position, was studied in the vicinity of the Kuroshio and Oyashio Currents, the Philippines, Celebes, Sulu and South China Seas, western and central equatorial and southeast Pacific Ocean. The abundance of Pronoctiluca was high- er, with a wide vertical distribution, in eutrophic temperate regions, whereas it was nearly absent in surface waters of oligotrophic tropical regions. Most of the specimens corresponded to P. spinifera. Pronoctiluca pelagica, covered by hyaline layers and with no flagella, is considered as an encysted form. The bipartition was only observed in P. acuta-P, spinifera forms, that together with the occurrence of intermediate forms between P. spinifera and P. pelagica suggest that they may correspond to developmental stages of a single species. Pronoctiluca is essential to understanding the evolutionary history of the alveolates.

关键词： Alveolata basal dinoflagellates Dinophyceae heterotrophic flagellate Noctilucales plankton

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Stepping up after spinal cord injury:negotiating an obstacle during walking

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Neural Regeneration Research 2025年第7期20卷 1919-1929页

作者： Alain Frigon Charly g.Lecomte Department of Pharmacology-Physiology Faculty of Medicine and Health SciencesUniversitéde SherbrookeCentre de recherche du Centre Hospitalier Universitaire de SherbrookeSherbrookeQCCanada

Every day walking consists of frequent voluntary modifications in the gait pattern to negotiate *** spinal cord injury,stepping over an obstacle becomes *** over an obstacle requires sensorimotor transformations in several structures of the brain,including the parietal cortex,premotor cortex,and motor *** information and planning are transformed into motor commands,which are sent from the motor cortex to spinal neuronal circuits to alter limb trajectory,coordinate the limbs,and maintain *** spinal cord injury,bidirectional communication between the brain and spinal cord is disrupted and animals,including humans,fail to voluntarily modify limb trajectory to step over an ***,in this review,we discuss the neuromechanical control of stepping over an obstacle,why it fails after spinal cord injury,and how it recovers to a certain extent.

关键词： biomechanics locomotion neurophysiology obstacle negotiation spinal cord injury

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Dicroerisma (Actiniscales, Dinophyceae) in the open Pacific Ocean, a gymnodinioid dinoflagellate with an endoskeleton

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Chinese Journal of Oceanology and Limnology 2008年第1期26卷 116-120页

作者： Fernando gómez Station Marine de Wimereux Université des Sciences et Technologies de Lille-Lille1 FRE 2816 ELICO CNRS 28 Avenue Foch BP 80 F-62930 Wimereux France

This study is the first to describe and illustrate the dinoflagellate genus Dicroerisma in the open Pacific Sea and in the southern hemisphere. Eleven individuals ascribed to Dicroerisma psilonereiella were encountered in subsurface waters (>70 m depth) from 34°N to 33°S. Another specimen that differs from the type is also illustrated. These findings reveal that Dicroerisma is a widespread genus and that there is tentative existence of another species within the genus.

关键词： Dicroerisma psilonereiella Actiniscales axostyle endoskeleton Dinophyceae the Pacific Ocean

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Lessons from International Students’ Reaction to the 2011 great East Japan Earthquake:The Case of the School of Engineering at Tohoku University

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International Journal of Disaster Risk Science 2013年第3期4卷 137-149页

作者： Oscar A.gómez graduate School of global Studies Doshisha UniversityKyoto 602-0898Japan

The objective of this study is to document the reaction of international students to the 11 March 2011 emergency in order to inform and improve disaster management strategies, both public and institutional. The study is based mainly on a questionnaire survey carried out in August 2011 and follow-up interviews with students and other stakeholders. It describes the background of Tohoku University’s School of Engineering and covers six different stages in the evolution of the emergency:(1) immediate response;(2) taking shelter in Sendai;(3) life in the city during the aftermath;(4) sheltering outside Sendai;(5) coming back;plus(6) an overview of the experience. Major findings include: the process of evacuation and safety confirmation was successful, yet the subsequent phases(2 and 3) went on mostly unmanaged;students relied mostly on secondary sources of information to make decisions, mainly family and friends of the same nationality, most of whom probably were not better informed than the students themselves. Based on the findings, suggestions for future disaster planning are advanced, as well as a discussion on the challenges of information provision during crisis.

关键词： disaster mostly great

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Differential response of injured and healthy retinas to syngeneic and allogeneic transplantation of a clonal cell line of immortalized olfactory ensheathing glia:a double-edged sword

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Neural Regeneration Research 2025年第8期20卷 2395-2407页

作者： María Norte-Muñoz María Portela-Lomba Paloma Sobrado-Calvo Diana Simón Johnny Di Pierdomenico alejandro gallego-Ortega Mar Pérez JoséMCabrera-Maqueda Javier Sierra Manuel Vidal-Sanz María Teresa Moreno-Flores Marta Agudo-Barriuso grupo de Investigación Oftalmología Experimental Departamento de OftalmologíaOptometríaOtorrinolaringología y Anatomía PatológicaFacultad de MedicinaUniversidad de MurciaInstituto Murciano de Investigación Biosanitaria(IMIB)Campus de Ciencias de la SaludMurciaSpain Experimental Sciences Faculty Universidad Francisco de VitoriaPozuelo de AlarcónMadridSpain Anatomy Histology and Neuroscience DepartmentMedicine FacultyUniversidad Autónoma de MadridMadridSpain Center of Neuroimmunology Service of NeurologyLaboratory of Advanced Imaging in Neuroimmunological DiseasesHospital Clínic of BarcelonaInstitut d’Investigacions Biomèdiques August Pi i Sunyer(IDIBAPS)and Universitat de BarcelonaBarcelonaSpain Medicine Faculty Universidad Francisco de VitoriaPozuelo de AlarcónMadridSpain

Olfactory ensheathing glia promote axonal regeneration in the mammalian central nervous system,including retinal ganglion cell axonal growth through the injured optic ***,it is unknown whether olfactory ensheathing glia also have neuroprotective *** ensheathing glia express brain-derived neurotrophic factor,one of the best neuroprotectants for axotomized retinal ganglion ***,we aimed to investigate the neuroprotective capacity of olfactory ensheating glia after optic nerve *** ensheathing glia cells from an established rat immortalized clonal cell line,TEg3,were intravitreally injected in intact and axotomized retinas in syngeneic and allogeneic mode with or without microglial inhibition or immunosuppressive *** and gene expression analyses were *** bulb-derived primary olfactory ensheathing glia and TEg3 express major histocompatibility complex classⅡ*** and syngenically transplanted TEg3 cells survived in the vitreous for up to 21 days,forming an *** axotomized retinas,only the allogeneic TEg3 transplant rescued retinal ganglion cells at 7 days but not at 21 *** these retinas,microglial anatomical activation was higher than after optic nerve crush *** intact retinas,both transplants activated microglial cells and caused retinal ganglion cell death at 21 days,a loss that was higher after allotransplantation,triggered by pyroptosis and partially rescued by microglial inhibition or ***,neuroprotection of axotomized retinal ganglion cells did not improve with these *** different neuroprotective properties,different toxic effects,and different responses to microglial inhibitory treatments of olfactory ensheathing glia in the retina depending on the type of transplant highlight the importance of thorough preclinical studies to explore these variables.

关键词： cell therapy immune recognition major histocompatibility complex class II(MHCII) neuroprotection olfactory ensheathing glia retinal ganglion cells

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An SPH Framework for Earthquake-Induced Liquefaction Hazard Assessment of geotechnical Structures

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 251-277页

作者： Sourabh Mhaski g.V.Ramana Department of Civil Engineering Indian Institute of Technology DelhiNew Delhi110016India

Earthquake-induced soil liquefaction poses significant risks to the stability of geotechnical structures *** understanding of the liquefaction triggering,and the post-failure large deformation behaviour is essential for designing resilient *** present study develops a Smoothed Particle Hydrodynamics(SPH)framework for earthquake-induced liquefaction hazard assessment of geotechnical *** coupled flowdeformation behaviour of soils subjected to cyclic loading is described using the PM4Sand model implemented in a three-phase,single-layer SPH framework.A staggered discretisation scheme based on the stress particle SPH approach is adopted to minimise numerical inaccuracies caused by zero-energy modes and tensile ***,non-reflecting boundary conditions for seismic analysis of semi-infinite soil domains using the SPH method are *** numerical framework is employed for the analysis of cyclic direct simple shear test,seismic analysis of a level ground site,and liquefaction-induced failure of the Lower San Fernando *** agreement for liquefaction triggering and post-failure behaviour demonstrates that the SPH framework can be utilised to assess the effect of seismic loading on field-scale geotechnical *** present study also serves as the basis for future advancements of the SPH method for applications related to earthquake geotechnical engineering.

关键词： Earthquake seismic liquefaction stress particle PM4Sand smoothed particle hydrodynamics(SPH)

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Zeckendorf representations with at most two terms to x-coordinates of Pell equations

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Science China Mathematics 2020年第4期63卷 627-642页

作者： Carlos A.gómez Florian Luca Departamento de Matematicas Universidad del ValleCali 25360Colombia School of Mathematics University of the WitwatersrandWits 2050South Africa Max Planck Institute for Mathematics Bonn 53111Germany Department of Mathematics Faculty of SciencesUniversity of OstravaOstrava 70103Czech Republic

In this paper,we find all positive squarefree integers d satisfying that the Pell equation X^2-d Y^2=±1 has at least two positive integer solutions(X,Y)and(X′,Y′)such that both X and X′have Zeckendorf representati... 详细信息

关键词： Pell equation Fibonacci numbers lower bounds for linear forms in logarithms reduction method

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