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Tumor invasion front in oral squamous cell carcinoma

World Journal of Clinical Cases 2022年第28期10卷 10387-10390页

作者： Juan Carlos Cuevas-González Maria Veronica Cuevas-González Leon Francisco Espinosa-Cristobal alejandro donohue cornejo Institute of Biomedical Sciences Universidad Autonoma de Ciudad JuarezJuarez 32320ChihuahuaMexico Faculty of Health Sciences Valle de las Palmas Universidad Autonoma de Baja CaliforniaTijuana 21480Baja CaliforniaMexico

Oral squamous cell carcinoma is a neoplasm that originates from the epithelial *** is usually more frequent between the fifth and sixth decades of life,and more than 90% of carcinomas of the oral cavity are squamous cell *** is an invasive neoplasia with a significant recurrence rate;40% of patients present with metastases in the cervical lymph nodes at the time of *** tumor invasion front is a characteristic of tumor growth,which can be infiltrative or *** histopathological parameters examined include the number of mitoses,depth of the tumor,invasion pattern,degree of keratinization,and nuclear *** the pathologist,these parameters are routinely evaluated but are not reported to the treating physician in all cases,which we consider to be useful information when determining the therapeutic route.

关键词： Oral squamous cell carcinoma Invasive neoplasia Therapeutic route Life Tumor growth Pleomorphism

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Hyalinizing clear cell carcinoma-a rare entity in the oral cavity: A case report

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World Journal of Clinical Cases 2020年第1期8卷 133-139页

作者： alejandro donohue-cornejo Oslei Paes de Almeida Celeste Sánchez-Romero León Francisco Espinosa-Cristóbal Simón Yobanny Reyes-López Juan Carlos Cuevas-González Stomatology Department Biomedical Sciences InstituteAutonomous University of Ciudad JuárezChihuahua 32310México Diagnosis Department Oral Pathology SectionDentistry Faculty of PiracicabaState University of CampinasSão Paulo 13414-903Brazil

BACKGROUND Hyalinizing clear cell carcinoma(HCCC)is an uncommon tumor that originates in the salivary *** neoplasia constitutes less than 1%of minor salivary gland *** SUMMARY A 67-year-old female visited the maxillofacial surgery department owing to a smooth,slightly yellowish protruding mass on the left side of the floor of the mouth,at the level of the molars;the tumor mass had a soft consistency on palpation and did not adhere to deep *** microscopical analysis of the excisional biopsy showed that the lesion was composed of sheets and cords of clear cells separated by thick eosinophilic bands of hyaline *** glandular tissue was absent,periodic acid-Schiff with and without diastase stains,and immunohistochemical reactions were performed to confirm the *** is the second case reported in the literature of HCCC arising in the floor of the *** HCCC is a rare salivary gland tumor that has not been studied *** diagnosis is usually challenging,because clinically,it can be confused with a benign neoplasm.

关键词： Hyalinizing clear cell carcinoma Salivary gland tumor Immunohistochemical reactions Case report

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Primary maxillary chondrosarcoma: A case report

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World Journal of Clinical Cases 2020年第1期8卷 126-132页

作者： Juan Carlos Cuevas-González Jesús Oscar Reyes-Escalera JoséLuis González Celeste Sánchez-Romero León Francisco Espinosa-Cristóbal Simón Yobanny Reyes-López Karla Lizette Tovar Carrillo alejandro donohue cornejo Stomatology Department Biomedical Sciences InstituteAutonomous University of Ciudad JuárezCiudad Juárez 32310Mexico Maxillofacial Surgery Department Faculty of DentistryJuarez University of the State of DurangoDurango 34000Mexico Madero Pathology Laboratory Durango 34000Mexico Molecular Pathology Area Faculty of DentistryUniversity of the RepublicMontevideo 10000Uruguay

BACKGROUND Sarcomas of the head and neck region are rare tumors,constituting less than 1%of malignant neoplasms in this area,of which few cases(20%)originate from bone or *** is a malignant neoplasm that develops in bone,with a predilection for the pelvis,chest wall,and scapula,and is uncommon in the maxilla and *** this type of lesion has locally aggressive behavior,destroying the affected bone,it can metastasize when it is not diagnosed early and compromise the patient's *** SUMMARY On intraoral examination of a 32-year-old female with a tumor in the middle third of the face,a well-defined rise in volume of approximately 3 cm in diameter was *** tomography with 3-dimensional reconstruction was performed,and we observed that the osteolytic lesion affected the vestibular cortex as the palatal *** and eosin staining revealed an appearance that was similar to mature hyaline cartilage,hypercellularity,nuclear and cellular pleomorphism,and multinucleated cells,with significant *** Determination of the clinical and histopathological characteristics of rare neoplasms in the maxillofacial region,such as chondrosarcomas,allows the pathologist and surgeon to make the appropriate therapeutic decisions,optimizing the patient’s prognosis.

关键词： Chondrosarcoma Rare neoplasms Maxillofacial region Case report

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