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The importance of post-cOVID condition phenotypes characterization to decipher the mechanisms underlying this post-viral syndrome

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World Journal of Pediatrics 2024年第6期20卷 633-634页

作者： Jon izquierdo-Pujol Sara Moron-Lopez Irsicaixa and Institute for Health Science Research Germans Trias i Pujol(IGTP) Can Ruti CampusBadalonaSpain Biomedicine doctoral programme Faculty of BiologyUniversity of BarcelonaBarcelonaSpain cIBERINFEc MadridSpain

The coronavirus disease-19(cOVID-19)outbreak,caused by the severe acute respiratory syndrome coronavirus 2(SARS-coV-2),was declared a global pandemic in March *** has affected over 700 million people worldwide and resulted in almost 7 million deaths,equating to a 1%mortality *** present,the majority of cOVID-19 cases are either asymptomatic or mild,typically resolving within two ***,between 1%and 10%of cOVID-19 survivors do not fully recover and experience a post-viral syndrome referred to as"long cOVID","post-acute cOVID-19 syndrome"(PASc),or"post-cOVID condition"(Pcc).This post-viral syndrome affects both adult and pediatric ***,most of the studies published to date evaluate the adult population,leaving a gap in our understanding of its impact on children and adolescents.

关键词： acute mortality respiratory

Sperm Quality in Holstein Bulls Friesian and Brahmans of Frozen Semen commercially

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Open Journal of Animal Sciences 2015年第3期5卷 229-231页

作者： alejandro córdova-izquierdo Gustavo Ruiz-Lang Román Espinosa-cervantes Adrían Emmanuel Iglesias-Reyes Maximino Méndez-Mendoza Rubén Huerta-crispín Abel Edmundo Villa-Mancera Ma. De Lourdes Juárez-Mosqueda Pedro Sánchez-Aparicio Jaime Olivares-Pérez Juan Eulogio Guerra-Liera Gerardo cansino-Arroyo Departamento de Producción Agrícola y Animal Universidad Autónoma Metropolitana Unidad Xochimilco México D.F. México Facultad de Veterinaria Benemérita Universidad Autónoma de Puebla Puebla México Departamento de Morfología FMVZ-UNAM México D.F. México Facultad de Veterinaria Universidad Autónoma del Estado de México Toluca México Unidad Académica de Medicina Veterinaria y Zootecnia Universidad Autónoma de Guerrero Guerrero México Facultad de Agronomía Universidad Autónoma de Sinaloa Culiacán México División Académica de ciencias Agropecuarias Universidad Juárez Autónoma de Tabasco Villahermosa México

The aim of this study was to assess sperm quality (motility, viability and acrosomal integrity) sperm from commercially frozen semen straws two breeds of bulls Bos taurus (holstein Frisian) and Bos indicus (Brahman). 9 commercial straws 0.5 ml of Holstein bull semen and 9 Brahman bull were thawed, they were kept for two hours at room temperature and motility, viability and acrosomal integrity (NAR) was assessed. The results were 30% motility, viability 40% and 30% of NAR in the Holstein breed. Brahma race for motility 40%, 50% and 40% viability was obtained NAR. In conclusion, according to the results of the variables analyzed, the Brahman breed in sperm quality was better than the Holstein breed;however, the results of both races meet minimum standards of quality sperm for use in artificial insemination (AI) field level.

关键词： Semen Thawed Bulls Frozen Semen Sperm Quality

Exercise benefits meet the esophagus

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Journal of Sport and Health Science 2024年第5期13卷 685-686页

作者： alejandro Santos-Lozano Pedro L.Valenzuela carmen Fiuza-Luces alejandro Lucia i+HeALTH European University Miguel de CervantesValladolid 47012Spain Research Institute of the Hospital 12 de Octubre(“imas12”) Madrid 28041Spain Department of Systems Biology University of AlcalaAlcala de Heranes 28801Spain Faculty of Sport Sciences Universidad Europea de MadridVillaviciosa de Odon(Madrid)28670Spain

Gastroesophageal reflux disease(GERD)is defined by recurrent and troublesome heartburn and effortless regurgitation or by the specific complications of this condition—that is,esophagitis,esophageal peptic strictures,and Barrett esophagus.1Although GERD is caused by gastric contents'reaching the esophagus,gastric juices can also reach other anatomical locations(pharynx,mouth,larynx,and airways),leading to(or worsening)extra-esophageal conditions(notably asthma)or symptoms(e.g.,wheezing,cough).1 Together with obesity,GERD is the main risk factor for gastroesophageal malignancies.

关键词： esophagus esophageal Barrett

Targeting autophagy by polyphenols to prevent glycative stress-toxicity in the brain

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Neural Regeneration Research 2024年第5期19卷 941-942页

作者： alejandro Ponce-Mora Eloy Bejarano Department of Biomedical Sciences School of Health Sciences and Veterinary SchoolUniversidad Cardenal Herrera-CEUCEU UniversitiesValenciaSpain

Glycative stress-a pathological hub in brain dysfunction:The nervous system is an intricate network that requires precise and complex *** recent years,growing evidence highlights the detrimental impact of glycative stress on brain homeostasis,which disables a network of vital processes,necessary for optimal function(Gómez et al.,2021).

关键词： homeostasis stress

Mitochondria–cGAS–STING axis is a potential therapeutic target for senescence-dependent inflammaging-associated neurodegeneration

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Neural Regeneration Research 2025年第3期20卷 805-807页

作者： JoséM.izquierdo centro de Biología Molecular Severo Ochoa(cBM) Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid(CSIC-UAM)MadridSpain

The word “senescence” comes from the Latin senescens, meaning “to begin to age”, and is characterized by a long-lasting but reversible block in proliferation, resulting from stress-induced cell cycle arrest of pre... 详细信息

关键词： Latin potential lasting

Development and maintenance of the ligular region of maize leaves

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Molecular Plant 2024年第8期17卷 1175-1177页

作者： Josh Strable alejandro Aragon-Raygoza Department of Molecular and Structural Biochemistry North Carolina State UniversityRaleighNCUSA

Roughly 1.2 billion tons of grain produced from maize(Zea mays)hybrids were harvested worldwide in 2022 on more than 200 million hectares(Food and Agricultural Organization statistics).Hybrid maize adapted to increased planting density,largely attributed to the upright angle of leaf blades,is a key factor for driving high grain yields over the last 50 years(Duvick et al.,2004).Leaf angle(LA)is a major breeding target for crop productivity due to its effects on canopy architecture,which impacts the amount of light intercepted by the leaf blade(cao et al.,2022).

关键词： breeding planting maize

Weather influenced nestling growth of an insectivorous but not a granivorous grassland passerine in Argentina

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Avian Research 2024年第2期15卷 156-162页

作者： Martín alejandro colombo Adrian Jauregui Luciano N.Segura Laboratorio de Ecología de Aves.Institute“Dr.Raúl A.Ringuelet”(ILPLA)-UNLP/cONIcET Boulevard 1201437La PlataB1900Buenos AiresArgentina

Nestling growth of birds can be affected by weather *** general,it is expected that higher temper-atures favor growth by improving food availability and nestling metabolism,while rain hinders it by reducing foraging ***,most of these patterns have been described in insectivorous cavity-nesting birds in temperate *** tested these predictions in two neotropical grassland ground-nesting birds with contrasting nestling diets and therefore potentially different responses to *** measured nestlings of the Hellmayr’s Pipit(Anthus hellmayri,an insectivorous passerine)and the Grassland Yellow-Finch(Sicalis luteola,which feeds its nestlings exclusively with seeds)during three breeding seasons(2017-2020)in central-eastern *** took measurements of tarsus and body mass,modeled growth curves using nonlinear mixed-effects models,and evaluated the effects of minimum daily temperature and precipitation during the growth period and the 30 days prior to *** pipits(60 nestlings from 21 nests),minimum temperatures during the growth period were positively associated with tarsus and body mass ***,there was a positive association between precipitation during the pre-hatching period and tarsus ***,none of the weather variables analyzed had significant effects on nestling growth of finches(131 nestlings from 35 nests).Dietary contrast between species may explain the different *** activity and abundance can be affected by weather variations within the span of a breeding season,whereas seeds may depend on conditions from previous years,making the effects harder to *** with reduced asymptotic size can have reduced chances of ***,pipit populations could be impacted if they experience cold and dry conditions during their breeding season,which is of major relevance in the current context of climate change.

关键词： Finches Grassland birds Neotropical birds Pipits Precipitation Temperature

Brent *** Texas Intermediate in the US petro derivatives price formation

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Petroleum Science 2024年第1期21卷 729-739页

作者： alejandro Almeida Antonio A.Golpe Juan Manuel Martín-Alvarez Jose carlos Vides Universidad Internacional de La Rioja Department of Quantitative Methods for Economics and BusinessLa RiojaSpain University of Huelva Department of Economics and Centro de Estudios Avanzados en FisicaMatematicas y Computacion and ICEIHuelvaSpain complutense University of Madrid Department of Applied and Structural Economics and History and ICEIMadridSpain

In this paper,we apply the spatial panel model to explore the relationship between the dynamic of two types of crude oil prices(WTI and Brent crude oil)and their refined products over *** the turbulent months of 2011,when cushing Oklahoma had reached capacity and the crude oil export ban removal in 2015 as breakpoints,we apply this method both in the full sample and the three resultant ***,results suggest our results show that both WTI and Brent display very similar behaviour with the refined ***,when attending to each regime,results derived from the first and third regimes are quite similar to the full sample ***,during the second regime,Brent crude oil became the benchmark in the petrol market,and it influenced the distillate ***,our model can let us determine the price-setters and price-followers in the price formation mechanism through refined *** results possess important considerations to policymakers and the market participants and the price formation.

关键词： crude oil prices Spatial panel model Refined products Price formation

Advancing pediatric exercise research:A focus on immunomics and cutting-edge technologies

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Journal of Sport and Health Science 2024年第5期13卷 679-681页

作者： Abel Plaza-Florido alejandro Lucia Shlomit Radom-Aizik Pediatric Exercise and Genomics Research center Department of PediatricsSchool of MedicineUniversity of California at IrvineIrvineCA 92617USA Faculty of Sport Sciences Universidad Europea de MadridMadrid 28670Spain Physical Activity Health Research Group(“PaHerg”) Research Institute of Hospital 12 de Octubre(“imas12”)Madrid 28041Spain

*** importance of immunomics in pediatric exercise research The profound effect that"acute"or"regular"exercise(i.e.,a single exercise session or repeated sessions over time,respectively)exerts on the immune system has been widely recognized.1 Acute exercise is largely"immuno-enhancing"(e.g.,it may even improve vaccine responses in"at-risk"patients),whereas regular exercise reduces the risk of chronic conditions(not only obesity,diabetes,or cardiovascular diseases,but also several types of cancer)partly due to its anti-inflammatory effects.

关键词： pediatric Acute vaccine