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Delivering a high-quality colonoscopy service fit for the 21st century

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Artificial Intelligence in Gastrointestinal Endoscopy 2024年第3期5卷 1-8页

作者： Brian Wing Kin ip Daniel Jin Keat Lee Kok Yang Tan Department of General Surgery Khoo Teck Puat HospitalSingapore 768828Singapore Department of Surgery Khoo Teck Puat HospitalSingapore 768828Singapore

Colorectal cancer(CRC)is the third most prevalent cancer *** is a concerning increase in its incidence among younger *** remains the gold standard for CRC *** the introduction of population-based bowel screening and increased public awareness,there has been a significant rise in referrals for *** providers worldwide will need to strategically evaluate how to allocate resources to adequately train the next generation of colonoscopists who will need to provide accurate endoscopic assessment and treatment for premalignant polyps and early *** review outlines the current workload challenges faced by colonoscopists whilst exploring emerging technologies such as artificial intelligence for adenoma ***,advanced endoscopic surgical techniques like endoscopic submucosal dissection are discussed.

关键词： Colonoscopy Colorectal cancer Bowel screening Polyps Adenoma

Parametric Body Model Development

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Computer Technology and Application 2012年第3期3卷 206-210页

作者： Peng Sixiang Chan Chee-Kooi Ameersing Luximon ip Wai Hung Institute of Textiles ＆ Clothing the Hong Kong Polytechnic University Hong Kong P.R. China Department of lndustrial and Systems Engineering the Hong Kong Polytechnic University Hong Kong P.R. China

This study shows a novel three-dimensional （3D） parametric body model development using cross-section control and control algorithm retrieved from anthropometric survey. The 3D parametric body model was shaped into the most common body shape of the young Hong Kong female and be able to automatically change its critical body shape according to the user＇s critical body dimension inputs. The control algorithm controls the profile of the parametric model is retrieved from an anthropometric survey using 3D scanner to study the profile change of body and the relation between some critical body dimensions. Compared to the traditional anthropometric surveys, the 3D body scanner provides more accurate body dimension and information as well as new body shape measurements.

关键词： Parametric body model anthropometric.

Prostate health index can stratify patients with Prostate Imaging Reporting and Data System score 3 lesions on magnetic resonance imaging to reduce prostate biopsies

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Asian Journal of Andrology 2024年第1期26卷 20-24页

作者： John Shung-Lai Leung Wai-Kit Ma Brian Sze-Ho Ho Stacia Tsun-Tsun Chun rong Na Yongle Zhan Chi-Yuen Ng Chi-Ho ip Ada Tsui-Lin Ng Yiu-Chung Lam Division of Urology Department of SurgeryQueen Mary HospitalUniversity of Hong KongHong KongChina Division of Urology Department of SurgeryPrincess Margaret HospitalHongKongChina

We aim to evaluate prostate health index as an additional risk-stratification tool in patients with Prostate Imaging Reporting and Data System score 3 lesions on multiparametric magnetic resonance *** with biochemical or clinical suspicion of having prostate cancer who underwent multiparametric magnetic resonance imaging in two tertiary centers(Queen Mary Hospital and Princess Margaret Hospital,Hong Kong,China)between January 2017 and June 2022 were ***-magnetic resonance imaging fusion biopsies were performed after prostate health index *** who only had Prostate Imaging Reporting and Data System score 3 lesions were further stratified into four prostate health index risk groups and the cancer detection rates were *** of the 747 patients,47.3%had Prostate Imaging Reporting and Data System score 3 lesions *** detection rate of clinically significant prostate cancer in this group was 15.0%.The cancer detection rates of clinically significant prostate cancer had statistically significant differences:5.3%in prostate health indexrostate health index 25.0-34.9,17.9%in prostate health index 35.0-54.9,and 52.6%in prostate health index≥55.0(Prostate health indexrostate *** health index could be used as an additional risk stratification tool for patients with Prostate Imaging Reporting and Data System score 3 *** could be avoided in patients with low prostate health index,with a small risk of missing clinically significant prostate cancer.

关键词： biopsy fusion biopsy magnetic resonance imaging prostate cancer prostate health index

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型格新居

城市住宅 2007年第8期14卷 34-41页

作者： Kenny ip 凯 Cats Interior Design

屋主与设计师的上一次合作，是打造一间以木材作主要装饰、具有浓厚泰国风情的安乐窝。在乔迁后，屋主希望拥有一间与之前完全不同感觉的新居，将更多不同的色彩，渗透于室内的每个角落。

关键词：四层复式单位室内装饰室内设计艺术风格

Effect of Initiation of Basal Insulin Glargine on Glycemic Control in Patients with Diabetes: Real Life Experience from Hong Kong

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Journal of Diabetes Mellitus 2017年第3期7卷 108-120页

作者： Chi-Kin Yeung Fhkcp Fhkam Wilson Wai-man Ngai ip-tim Lau Department of Medicine Tseung Kwan O Hospital Hong Kong China Sanofi (Hong Kong) Ltd. Hong Kong China

Introduction: To assess the changes in glycemic control after initiating or switching to a basal insulin analogue in patients with diabetes mellitus. Methods: A retrospective, observational analysis was conducted using electronic data from a Hong Kong regional hospital. Data from adult patients with type 1 and 2 diabetes mellitus (T1DM and T2DM, respectively) who had been prescribed with basal insulin glargine in 2008-2010, with recorded HbA1c levels at the time of initiation, at 6 and 12 months thereafter, were analysed. Results: Data from 106 eligible patients were analysed. Substantial reduction in HbA1c and fasting sugar levels were reported in both T1DM (Δ HbA1c = 1.5%, Δ FBG = 1.3 mmol/L p rom 69% to 62% in T1DM but increased from 26% to 36% in T2DM patients. All hypoglycaemic episodes recorded were either asymptomatic or mild and self-limiting. Only 4% of the patients discontinued treatment at the end of 12 months. Conclusions: In real life clinical practice, a single daily basal insulin analogue therapy provided effective glycemic control with an acceptable risk of mild hypoglycaemia.

关键词： Glycemic Control Insulin Initiation Insulin Glargine Type 1 Diabetes Mellitus Type 2 Diabetes Mellitus Hong Kong

Mothers’ health-related quality of life: Its relationship with children’s health-related quality of life and behavior in low-income families

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Family Medicine and Community Health 2016年第4期4卷 4-12页

作者： rosa Sze Man Wong Vivian Yawei Guo Patrick ip Carlos King Ho Wong Esther Yee Tak Yu Colman Siu Cheung Fung Cindy Lo Kuen Lam Department of Family Medicine and Primary Care The University of Hong KongAp Lei Chau ClinicAp Lei ChauHong KongChina Department ofPaediatrics and Adolescent Medicine TheUniversity of Hong KongQueen Mary HospitalHong KongChina

Objective:To examine the association between mothers’health-related quality of life(HRQOL)and their children’s HRQOL and behavior in low-income ***:Mothers of 278 children aged 6-12 years from low-income families were invited to complete the Child Health Questionnaire Parent Form 50(CHQ-PF50)and the Strength and Dif-ficulties Questionnaire(SDQ)for their children as well as the 12-item Short-Form Health Survey version 2(SF-12v2)and the Patient Health Questionnaire-2(PHQ-2).Multiple linear regressions with mother-child pairs as the unit of analysis were performed to examine the associations between maternal and child variables with adjustment of mother-and child-level ***:Compared with the general population,low-income mothers had a lower mean SF-12v2 mental component summary score and their children also had lower mean CHQ-PF50 physi-cal and psychosocial summary scores and SDQ total difficulties *** of mothers with SF-12v2 scores below the population mean of 50 had significantly worse CHQ-PF50 scores and higher SDQ total difficulties *** mother’s PHQ-2 depression status had no association with the child’s CHQ-PF50 ***:Our findings suggest that more attention should be paid to reducing the negative impact of health problems on mothers’daily roles in childcare in low-income families.

关键词： Health-related quality of life child health child behavior low income

Functional roles of melanocortin-4 receptor in hippocampal synapse

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Functional roles of melanocortin-4 receptor in hippocampal s...

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Amy K.Y.FU Nancy Y.ip Division of Life Science Molecular Neuroscience Center and State Key Laboratory of Molecular NeuroscienceThe Hong Kong University of Science and TechnologyClear Water Bay

＜正＞Objective Melanocortin-4 receptor（MC4R）,which belongs to the G-protein coupled receptor（GPCR） superfamily,is one of the five melanocortin receptors（MCRs）that is expressed abundantly in the central nervous ***4R is activated by various endogenous ligands including melanocyte stimulating hormone（MSH）,and adrenocorticotropin *** central melanocortin signaling in the hypothalamus-pituitary-adrenal axis system is critical for regulating various aspects of energy homeostasis and feeding *** MC4R is highly expressed in other brain regions such as cortex and hippocampus,the roles of MC4R in these regions remain *** this study,the functional role of MC4R in synapse plasticity in hippocampus is *** The regulation of MC4R protein in hippocampal neurons was examined using immunocytochemical analysis and Western blot *** function of MC4R in hippocampal neurons was studied by RNA interference using calcium phosphate ***（1）MC4R protein increases in rat hippocampus upon development and enriched at the synaptic compartment.（2）Knockdown of MC4R in cultured rat hippocampal neurons results in a regulation in the density of dendritic spines,the sites where excitatory synapses reside.（3）Stimulation of MC4R increases the cAMP level in hippocampal *** MC4R regulates the synapse functions through modulating the morphology of dendritic spines.

关键词： Melanocortin-4 receptor cyclic AMP dendritic spines

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股市还是晴雨表吗？

工程经济 2007年第5期23卷 12-13页

作者： Greg　ip

人们一直有股市是经济增长晴雨表的说法，不过，近几年来，这只晴雨表的准确性实在不怎么样。

关键词：晴雨表股市经济增长

Characteristics of Chemical Modified Activated Carbons from Bamboo Scaffolding

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Chinese Journal of Chemical Engineering 2012年第3期20卷 515-523页

作者： W.H.Cheung S.S.Y.Lau S.Y.Leung A.W.M.ip G.McKay Department of Chemical and Biomolecular Engineering the Hong Kong University of Science and TechnologyHong KongChina Scott Wilson Ltd 38th Floor MetroPlaza Tower 1Kwai FongHong KongChina

In this study, bamboo scaffolding was used to produce activated carbon by carbonization at 600 ℃ and 900 ℃with the purge of nitrogen. The 600 ℃ char was then further modified chemically by acids and alkalis by reflux for 6 hours. The produced chars were then characterized by nitrogen adsorption isotherm, He pyncometry, pH, elemental analysis and Boehm titration. For most of the chemically modified carbons, the micropore surface areas and volumes have increased compared with the 600 ~C char, while the mesopore surface areas and volumes slightly decreased, which may have been due to the dissolving of some of the permeated inorganic matter and oxidizing deposited carbon that blocks the pore openings. For the acidic modified carbons, larger amounts of acidic groups were present in the carbons after being activated by phosphoric acid, phosphoric acid furth, er treated with 2 mol-L-1nitric-acid, and calcium hydroxide. Although carbon treated with 2 mol.L-1 and 5 mol·L-1 nitric acid also produced high acidity, the surface areas and pore volumes were relatively low, due to the destruction of pores by nitric acid oxidation. The reduction of porosity may impair the adsorption capacity.

关键词： activated carbon bamboo surface area chemical activation porosity surface functional group