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Clinical profile and outcomes in very elderly patients with atrial fibrillation anticoagulated with rivaroxaban: data from the EMIR study

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Journal of Geriatric Cardiology 2024年第7期21卷 723-732页

作者： Francisco Marín Manuel Anguita Sánchez Iñaki Lekuona Marcelo Sanmartín Fernán-dez Vivencio Barrios Carlos Perez Muñoz Juan Cosín-Sales alejan.ro ipérez cabeza Vanesa roldán Schilling Carles Rafols Priu Esteban Orenes-Piñero María Asunción Es-teve-Pastor Department of Cardiology Hospital Clínico Universitario Virgen de la ArrixacaIMIB-ArrixacaUniversity of MurciaCIBERCVMurciaSpain Department of Cardiology Hospital Reina Sofía CórdobaIMIBICUniversity of CordobaCIBERCVCórdobaSpain Hospital Galdakao-Usansolo BizkaiaSpain Department of Cardiology Hospital Uni-versitario Ramony CajalCIBERCVMadridSpain Department of Cardiology University Hospital Ramóny CajalAl-caláUniversityMadridSpain Medical Center La Capillita Sanlúcar de Barrameda.Private cardiology clinicJerez de la FronteraSpain Department of Cardiology Hospital Arnau de VilanovaValenciaSpain Department of Car-diology Virgen de la Victoria University HospitalCIBERCV.MalagaSpain Department of Haematology Hospital Clínico Universitario Virgen de la ArrixacaUniversity of MurciaMurciaSpain Department of Medical Affairs Bayer HispaniaBarcelonaSpain Department of Biochemistry and Molecular Biology-A University of MurciaMurciaSpain

Objectives To analyze the clinical profile,adequacy of treatment with rivaroxaban and outcomes in octogenarians with atrial fibrillation(AF),taking rivaroxaban in clinical *** Observational and non-interventional study that included AF adults recruited from 79 Spanish centers,anticoagulated with rivaroxaban ≥ 6 months before being *** were analyzed according to age(≥ 80 vs.roxaban was adequately prescribed in 83.4% of patients,but more frequently in the younger population(71.1% vs.89.1%;P = 0.039).After a mean follow-up of 2.2 ± 0.6 years,annual rates of stroke + systemic embolism + transient ischemic attack,MACE,cardiovascular death and major bleeding were 1.03%,1.24%,1.03% and 1.75%,respectively,in octogenarian *** for progressive heart failure death and major bleeding,rates of outcomes in octogenarians were similar compared to younger *** octogenarians,the concomitant use of antiplatelet agents and non-severe dementia were independently associated with the development of ischemic stroke,whereas previous coronary revascularization and heart failure with MACE,and higher HAS-BLED score with major *** In clinical practice,around one third of patients taking rivaroxaban are *** patients have many comorbidities and a high thromboembolic *** that,rates of adverse events remain *** is adequately prescribed in the majority of octogenarians.

关键词： patients atrial bleeding

Testing coeffcients of AR and bilinear time series models by a graphical approach

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Science China Mathematics 2008年第12期51卷 2304-2314页

作者： ip WaiCheung Department of Mathematics The Hong Kong Polytechnic University

AR and bilinear time series models are expressed as time series chain graphical models, based on which, it is shown that the coefficients of AR and bilinear models are the conditional correlation coefficients conditioned on the other components of the time series. Then a graphically based procedure is proposed to test the significance of the coeffcients of AR and bilinear time series. Simulations show that our procedure performs well both in sizes and powers.

关键词： AR model bilinear model graphical model

ON ProBLEMS OF FRACTURE OF MATERIALS IN COMPRESSION ALONG TWO INTERNAL PARALLEL CRACKS

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Applied Mathematics and Mechanics(English Edition) 1997年第6期18卷 517-528页

作者： Guz, AN Nazarenko, VM Starodubtsev, ip Natl Acad Sci Ukraine Inst Mech UA-252057 Kiev Ukraine

The fracture of materials under the action of compressive forces, directed along cracks which are parallel in plane can,lot be described within the framework of the linear fracture mechanics. The criteria of fracture of the Griffith-Irvin or COC type, used in classical linear fracture mechanics, are not applicable in this problem, since these forces have no influence on stress intensity coefficients and on values of cracks opening([1, 2]). The problems of such a class may be described only by using new approaches. One of possible approaches is presented by the first author, which involves using linearized relations, derived from exact non-linear equations of deformable solid body mechanics([3, 4, 5]). It should be remarked here that this approach has been widely used in problems of deformable bodies stability. As a criterion of the initiation of fracture the criterion of local instability near defects of the crack type is used. In these cases the process of loss of stability initiates the fracture process.

关键词： fracture internal parallel crack criterion of the initiation of fracture

Versatile guardians: regenerative regulatory T cells in Parkinson’s disease rodent models

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Signal Transduction and Targeted Therapy 2023年第12期8卷 5578-5580页

作者： Chi Wang ip Jörg Wischhusen Department of Neurology University Hospital of WürzburgWürzburgGermany Section for Experimental Tumor Immunology Department of Obstetrics and GynecologyUniversity Hospital of WürzburgWürzburgGermany

In a paper published in Nature,Park and colleagues have explored an innovative approach for improving adoptive neuron transfer,with possible implications for Parkinson´s Disease(PD)and other neurodegenerative diseases.1 By co-transplanting autologous regulatory T(Treg)cells,they managed to reduce surgical trauma-induced neuroinflammation,enhance the safety of cell replacement therapy by inhibiting proliferation of non-dopaminergic cells and improve therapeutic outcomes.

关键词： inflammation inhibiting trauma

ARMILLARIA TRAPPING IN A PINUS KORAIENSIS PLANTATION IN NORTHEAST CHINA

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Journal of Northeast Forestry University 1992年第2期3卷 1-12页

作者： David Waigcck ip Forestry Canada Winnipeg Manitoba Canada R3C 1A6

Trap bags were used to assess the presence of an Armillaria species in a Pinus koraiensis plantation in Heilongjiang, China. 216 trap bags containing bark were placed in three plots at 2×2m spacing. After 10 weeks, the presence of Armillaria was determined from the growth of rhizomorphs in the trap bags. The trap bag method proved successful in determining the presence of viable Armillaria rhizomorphs where only a few dead trees showed signs of the disease. The distribution of positive traps corresponded generally with the presence of rhizomorphs in the soil taken from the trap holes. However, the trap bags were superior to soil samples for evaluating the presence of viable rhizomorphs. The fresh, abundant rhizomorphs were easily identified by persons inexperienced in the assessment of Armillaria root rot. Several practical problems need to be solved before the method is applicable in general forest management in China.

关键词： Armillaria,Disease management Northeast China Pinus koraiensis Plantation discase Trapping

AN OSCILLATION CRITERIA FOR SECOND ORDERFUNCTIONAL EQUATIONS

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Acta Mathematica Scientia 2002年第1期22卷 56-62页

作者：申建华 ip. Stavroulakis Hunan Normal Univ Dept Math Changsha 410081 Peoples R China Univ Ioannina Dept Math GR-45110 Ioannina Greece

This paper is concerned with the oscillation of second order linear functional equations of the form x(g(t)) = p(t)x(t) + Q(t)X(g(2)(t)), Where p, Q, g : [t(0), infinity) --> R+ = [0, infinity) are given real valued functions such that g(t) not equivalent to t, lim(t-->infinity) g(t) = infinity. It is proved here that when 0 less than or equal to m := lim inf(t-->infinity) Q(t)P(g(t)) less than or equal to 1/4 all solutions of this equation oscillate if the condition lim(t-->infinity) sup Q(t)P(g(t)) > (1 + root1 -4m/2)(2) (*) is satisfied. It should be emphasized that the condition (*) can not be improved in some sense.

关键词： oscillation nonoscillation functional equations

Field test of multi-hop image sensing network prototype on a city-wide scale

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Digital Communications and Networks 2019年第2期5卷 131-137页

作者： Xianhui Che Barry ip Zhuge Yan School of Computer Science University of HertfordshireALIO 9GHUK robert Kennedy College Technoparkstrasse 18005 ZurichSwitzerland Department of Electrical and Electronic Engineering University of Nottingham Ningbo Campus315100NingboChina

Wireless multimedia sensor networks drastically stretch the horizon of traditional monitoring and surveillance systems. Most existing research has utilized Zigbee or WiFi as the communication technology. Both technologies use ultra-high frequencies (primarily 2.4 GHz) and suffer from a relatively short transmission range (i.e., 100 m line-of-sight). The objective of this study is to assess the feasibility and potential of transmitting image information using RF modules with lower frequencies (e.g., 433 MHz) to achieve a larger-scale deployment as in a city scenario. The Arduino platform is used because of its low cost and simplicity. Details of hardware properties are provided in this article, and we investigate optimum configurations for the system. After achieving an initial range test transmission distance of more than 2000 m line-of-sight, the prototype network is installed in a real life city plot for further examination of performance. A range of suitable applications is proposed and suggestions for future research are provided.

关键词： Image sensing Prototype Field test

Model Checking for a General Linear Model with Nonignorable Missing Covariates

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Acta Mathematicae Applicatae Sinica 2012年第1期28卷 99-110页

作者： Zhi-hua SUN Wai-Cheung ip Heung WONG School of Mathematical sciences Graduate University of Chinese Academy of SciencesBeijing 100049China Academy of Mathematics and Systems Science Chinese Academy of SciencesBeijing 100190China Department of Applied Mathematics Hong Kong Polytechnic UniversityHung HomKowloonHong KongChina

In this paper, we investigate the model checking problem for a general linear model with nonignorable missing covariates. We show that, without any parametric model assumption for the response probability, the least squares method yields consistent estimators for the linear model even if only the complete data are applied. This makes it feasible to propose two testing procedures for the corresponding model checking problem： a score type lack-of-fit test and a test based on the empirical process. The asymptotic properties of the test statistics are investigated. Both tests are shown to have asymptotic power 1 for local alternatives converging to the null at the rate n-r, 0 ≤ r 〈 1/2. Simulation results show that both tests perform satisfactorily.

关键词： general linear model model checking nonignorable missing covariates sensitivity analysis

Surface thermophysical properties on the potentially hazardous asteroid (99942) Apophis

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Research in Astronomy and Astrophysics 2017年第7期17卷 67-76页

作者： Liang-Liang Yu Jianghui Ji Wing-Huen ip Space Science Institute Macao University of Science and Technology CAS Key Laboratory of Planetary Sciences Purple Mountain ObservatoryChinese Academy of Sciences Institute of Astronomy National Central University

We investigate the surface thermophysical properties（thermal emissivity, thermal inertia,roughness fraction and geometric albedo） of asteroid（99942） Apophis, using the currently available mid-infrared observations from CanariC am on Gran Telescopio CANARIAS and far-infrared data from PACS on Herschel, based on the Advanced Thermophysical Model. We show that the thermal emissivity of Apophis should be wavelength dependent from 8.70 μm to 160 μm, and the maximum emissivity may appear around 20 μm, similar to that of Vesta. Moreover, we further derive the thermal inertia,roughness fraction, geometric albedo and effective diameter of Apophis within a possible 1σ scale of Γ = 100（-52）^（＋100）＋Jm^（-2）s^-0.5K^-1, fr = 0.78~1.0, pv = 0.286（-0.026）^（＋0.030） and D（eff） = 378（-25）^（＋19）m, and 3σscale of Γ = 100（-100）^（＋240）Jm^（-2）s^-0.5 K^-1, fr = 0.2~1.0, pv = 0.286（-0.029）^（＋0.039） and D（eff） = 378（-29）^（＋27） m. The derived low thermal inertia but high roughness fraction may imply that Apophis could have regolith on its surface, where stronger space weathering but weaker regolith migration has happened in comparison with asteroid Itokawa. Our results show that small-size asteroids could also have fine regolith on the surface, and further infer that Apophis may have been delivered from the Main Belt by the Yarkovsky effect.

关键词： techniquest hermal infrared -- variables thermal inertia -- asteroid individual (99942)Apophis