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Simulating bicycle traffic by the intelligent-driver model-Reproducing the traffic-wave characteristics observed in a bicycle-following experiment

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journal of Traffic and Transportation Engineering(English Edition) 2020年第1期7卷 19-29页

作者： Valentina Kurtc martin Treiber Institute of Applied Mathematics and Mechanics Peter the Great St.Petersburg Polytechnic UniversitySt.Petersburg 195251Russia Institute for Transport and Economics Technische Universitat DresdenDresden 01062Germany

Bicycle traffic operations become increasingly important and yet are largely ignored in the traffic flow community,until *** hypothesize that there is no qualitative difference between vehicular and bicycle traffic flow dynamics in single-file case,so the latter can be described by reparameterized car-following *** test this proposition,we reproduce German(Andresen et al.,2014)and Chinese(jiang et al.,2016)bicycle experiments on a ring with the intelligent-driver model(IDM)and compare its fit quality(calibration)and predictive power(validation)with that of the necessary-deceleration-model(NDM),which is specifically designed for bike *** find similar quality metrics for both models,so the above hypothesis of a qualitative equivalence cannot be ***,calibration errors of the IDM turn up to be slightly smaller compared to the NDM *** NDM represents significant calibration errors for high flow densities,which correspond to flow states,when stop-and-go wave *** to validation tests,the IDM outperforms the NDM as *** two types of validation techniques we discover that inter-driver variation is much higher than the intra-driver variation for bicycle *** coincides with the results obtained from vehicular traffic experiments(NGSIM trajectory data).In addition,we suggest the measure for quantitative comparison of two microscopic fundamental diagrams,which are derived from experimental data and simulated *** analysis of speed-density relations provides more or less the same results for both models.

关键词： Bicycle traffic Car-following model Stop-and-go waves Calibration Validation Fundamental diagram

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Liver transplantation for malignancy:current treatment strategies and future perspectives

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World journal of Gastroenterology 2014年第18期20卷 5331-5344页

作者： Christina Hackl Hans j Schlitt Gabriele I Kirchner Birgit Knoppke martin Loss Department of Surgery University Hospital Regensburg93053 RegensburgGermany Department of Internal Medicine I University Hospital Regensburg93053 RegensburgGermany Department of Pediatrics and juvenile Medicine University Hospital Regensburg93053 RegensburgGermany

In 1967,Starzl et al performed the first successful liver transplantation for a patient diagnosed with *** the following,liver transplantation was considered ideal for complete tumor resection and potential cure from primary hepatic *** reports of liver transplantation for primary and metastatic liver cancer however showed disappointing results and the strategy was soon ***1996,Mazzaferro et al introduced the Milan criteria,offering liver transplantation to patients diagnosed with limited hepatocellular *** then,liver transplantation for malignant disease is an ongoing subject of preclinical and clinical *** this context,several aspects must be considered:(1)Given the shortage of deceased-donor organs,long-term overall and disease free survival should be comparable with results obtained in patients transplanted for nonmalignant disease;(2)In this regard,living-donor liver transplantation may in selected patients help to solve the ethical dilemma of optimal individual patient treatment vs organ allocation justice;and(3)Ongoing research focusing on perioperative therapy and antiproliferative immunosuppressive regimens may further reduce tumor recurrence in patients transplanted for malignant disease and thus improve overall *** present review gives an overview of current indications and future perspectives of liver transplantation for malignant disease.

关键词： Hepatocellular Fibrolamellar Carcinoma Cholangiocellular Hepatoblastoma Liver metastases

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Inflation Targeting and Inflation Persistence

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Economic and Political Studies 2015年第1期3卷 3-17页

作者： GEORGE j.BRATSIOTIS jAKOB MADSEN CHRISTOPHER martin the School of Social Sciences University of Manchester the Department of Economics Monash University the Department of Economics University of Bath

This paper argues that the adoption of an inflation target reduces the persistence of *** develop the theoretical literature on inflation persistence by introducing a Taylor Rule for monetary policy into a model of persistence and showing that inflation targets reduce inflation *** investigate changes in the time series properties of inflation in seven countries that introduced inflation targets in the late 1980s or early *** find that the persistence of inflation is greatly reduced or eliminated following the introduction of inflation targets.

关键词： Taylor Rule inflation targeting Phillips Curve inf

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Hydrothermal Processes in the Solar System：A Review

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地质科技情报 2008年第1期27卷 1-12页

作者： Franco PIRAjNO martin j. Van KRANENDONK Long XIAO Geological Survey of Western Australia 100 Plain Street Perth WA 6004 Australia Research Center forSpace Science ＆ Technology Faculty of Earth Sciences China University of Geosciences Wuhan 430074 China

最近美国航空与空间计划署(NASA)开展的卡西尼—惠更斯外空探测计划发现,在直径为500km的卫星——土卫二上存在水冰和间隙泉的喷发活动。这一现象和在火星上工作的"机遇号"和"勇气号"漫游车所发现的液态水一起,证明了除地球以外的其他... 详细信息

最近美国航空与空间计划署(NASA)开展的卡西尼—惠更斯外空探测计划发现,在直径为500km的卫星——土卫二上存在水冰和间隙泉的喷发活动。这一现象和在火星上工作的"机遇号"和"勇气号"漫游车所发现的液态水一起,证明了除地球以外的其他星球上过去和现在都存在水,其中的一些星体还有火山活动的证据,这意味着这些星球上可能存在过热液活动地质过程。讨论了火星、木卫二和土卫二可能存在的热液系统类型。这些热液系统类型是根据地球上的构造背景进行相似性研究后得出的,例如海底、火山和裂谷系统。将东非裂谷和贝加尔湖裂谷系统与火星Tharsis高原上巨大的水手大峡谷进行了对比,这些地区都是由地幔柱作用下构造—热液活动导致的地壳抬升、火山和裂谷作用。在火星上,地下冰或低温层会在火山活动和(或)小行星或彗星撞击作用下溶解而形成热液对流。

关键词：热液活动过程火星木卫二土卫二

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Encapsulating peritoneal sclerosis

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World journal of Gastroenterology 2018年第28期24卷 3101-3111页

作者： Christopher j Danford Steven C Lin martin P Smith jacqueline L Wolf Division of Gastroenterology and Hepatology Beth Israel Deaconess Medical Center Harvard Medical School Department of Radiology Beth Israel Deaconess Medical Center Harvard Medical School

Encapsulating peritoneal sclerosis(EPS) is a debilitating condition characterized by a fibrocollagenous membrane encasing the small intestine, resulting in recurrent small bowel obstructions. EPS is most commonly associated with long-term peritoneal dialysis, though medications, peritoneal infection, and systemic inflammatory disorders have been implicated. Many cases remain idiopathic. Diagnosis is often delayed given the rarity of the disorder combined with non-specific symptoms and laboratory findings. Although cross-sectional imaging with computed tomography of the abdomen can be suggestive of the disorder, many patients undergo exploratory laparotomy for diagnosis. Mortality approaches 50% one year after diagnosis. Treatment for EPS involves treating the underlying condition or eliminating possible inciting agents(i.e. peritoneal dialysis, medications, infections) and nutritional support, frequently with total parenteral nutrition. EPSspecific treatment depends on the disease stage. In the inflammatory stage, corticosteroids are the treatment of choice, while in the fibrotic stage, tamoxifen may be beneficial. In practice, distinguishing between stages may be difficult and both may be used. Surgical intervention, consisting of peritonectomy and enterolysis, is timeconsuming and high-risk and is reserved for situations in which conservative medical therapy fails in institutions with surgical expertise in this area. Herein we review the available literature of the etiology, pathogenesis, diagnosis, and treatment of this rare, but potentially devastating disease.

关键词： Abdominal cocoon Sclerosing encapsulating peritonitis Peritoneal sclerosis Peritonectomy Enterolysis Peritoneal dialysis Tamoxifen Corticosteroids

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No evidence for increased cell entry or antibody evasion by Delta sublineage AY.4.2

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Cellular & Molecular Immunology 2022年第3期19卷 449-452页

作者： Prerna Arora Amy Kempf Inga Nehlmeier Luise Graichen martin S.Winkler martin Lier Sebastian Schulz Hans-martin jäck Stefan Pöhlmann Markus Hoffmann Infection Biology Unit German Primate CenterKellnerweg 437077GöttingenGermany Faculty of Biology and Psychology Georg-August-University GöttingenWilhelmsplatz 137073GöttingenGermany Department of Anesthesiology University of Göttingen Medical CenterGeorg-August University GöttingenRobert-Koch-Straße 4037075GöttingenGermany Division of Molecular Immunology Department of Internal Medicine 3Friedrich-Alexander University Erlangen-NürnbergGlückstraße 691054ErlangenGermany

Since the beginning of the COVID-19 pandemic,multiple SARS-CoV-2 variants have *** some variants spread only locally,others,referred to as variants of concern,disseminated globally and became drivers of the *** SARS-CoV-2 variants harbor mutations relative to the virus circulating early in the pandemic,and mutations in the viral spike(S)protein are considered of particular relevance since the S protein mediates host cell entry and constitutes the key target of the neutralizing antibody *** a consequence,mutations in the S protein may increase SARS-CoV-2 infectivity and enable its evasion of neutralizing ***,mutations in the S protein can modulate viral transmissibility and pathogenicity.

关键词： SARS-CoV-2 AY.4.2 Delta Host cell entry Antibody evasion

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How can stream bank erosion be predicted on small water courses?Veri?cation of BANCS model on the Kubrica watershed

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International journal of Sediment Research 2021年第3期36卷 419-429页

作者： Zuzana Allmanová Máaria Vl?kováa martin jankovsky Michal Allman jáan Mergani? Department of Forest Harvesting Logistics and Ameliorations Faculty of Forestry Technical University in Zvolen Department of Forestry Technology and Constructions Faculty of Forestry and Wood Sciences Czech University of Life Sciences Prague

The current paper deals with the evaluation of the BANCS erosion prediction model and its two componentsethe Bank Erosion Hazard Index（BEHI） and Near-Bank Stress（NBS） indices. To construct the erosion prediction curves, 18 experimental sections were established on the Kubrica Stream, district of Trencín, Slovakia. Each section was assessed through the NBS index and BEHI index and real annual bank erosion was measured using erosion toe pins. Subsequently, the relations between the BEHI and real annual bank erosion was assessed through regression and correlation analyses. The relation proved to be moderately strong, with the correlation coefficient（R） reaching 0.47. Further, the relation between the NBS index and real annual bank erosion was evaluated, which was also moderately strong, with R= *** on the measured data, two erosion prediction curves were constructed, the first for moderate BEHI, with R= 0.69 and coefficient of determination（R2） of 0.47 and the second for high BEHI with R=0.74 and R2= 0.55. The prediction curves were based on data from one year of measurements and can, therefore, be used only for discharges that occurred within that year and in the region where the model was developed. In the current case, according to runoff Curve Numbers（CN）, the real culmination discharge was Q ? 1.88 m3/s, which is roughly equivalent to 1.5-year recurrence interval flow（Q1.5）.

关键词： Bank erosion Bank assessment for non-point source consequences of sediment (BANCS) Bank erosion hazard index Near-bank stress index Erosion prediction curves

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Alternative polyadenylation events in epithelial cells sense endometritis progression in dairy cows

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journal of Integrative Agriculture 2023年第6期22卷 1820-1832页

作者： Meagan j.STOTTS Yangzi ZHANG Shuwen ZHANG jennifer j.MICHAL juan VELEZ Bothe HANS martin MAQUIVAR Zhihua jIANG Department of Animal Sciences and Center for Reproductive Biology Washington State UniversityPullmanWA 99164-7620USA Aurora Organic Farms PlattevilleCO 80651USA

Endometritis(inflammation of the endometrial lining) is one of the most devastating reproductive diseases in dairy cattle, resulting in substantial production loss and causing more than $650 million in lost revenue annually in the *** hypothesize that alternative polyadenylation(APA) sites serve as decisive sensors for endometrium health and disease in dairy cows. Endometrial cells collected from 18 cows with purulent vaginal discharge scored 0 to 2 were used for APA profiling with our whole transcriptome termini site sequencing(WTTS-seq) method. Overall, pathogens trigger hosts to use more differentially expressed APA(DE-APA), more intronic DE-APA, more DE-APA sites per gene and more DE-genes associated with inflammation. Host CD59 molecule(CD59), Fc fragment of IgG receptor IIa(FCGR2A), lymphocyte antigen 75(LY75) and plasminogen(PLG) may serve as initial contacts or combats with pathogens on cell surface, followed by activation of nuclear receptor subfamily 1 group H member 4(NR1H4) to regulate AXL receptor tyrosine kinase(AXL), FGR proto-oncogene, Src family tyrosine kinase(FGR), HCK protooncogene, Src family tyrosine kinase(HCK) and integrin subunit beta 2(ITGB2) for anti-inflammation. This study is the first to show significance of cilium pathways in endometrium health and animal reproduction. MIR21 and MIR30A would be perfect antagonistic biomarkers for diagnosis of either inflammation or anti-inflammation. These novel findings will set precedent for future genomic studies to aid the dairy industry develop new strategies to reduce endometritis incidence and improve fertility.

关键词： organic dairy endometritis alternative polyadenylation infection progression antagonistic biomarkers

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小型船舶上的液化石油气用具—火灾事故调查(英文)

小型船舶上的液化石油气用具—火灾事故调查(英文)

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2007年全国失效分析学术会议

作者： Richard j.martin Brad A．McGoran William D．Chapman 毅博科技咨询公司洛杉矶办事处 Smith Chapman & Campbell律师事务所

在美国西北太平洋地区的一次野外垂钓活动中,一名游客在向导的渔船中由于爆燃而严重受伤。事故的凋查表明,燃油供应商销售并在渔船中安装了非标准的液化石油气加热系统,该系使用的元件未达到液化石油气的使用标准。如果使用了正确的加... 详细信息

在美国西北太平洋地区的一次野外垂钓活动中,一名游客在向导的渔船中由于爆燃而严重受伤。事故的凋查表明,燃油供应商销售并在渔船中安装了非标准的液化石油气加热系统,该系使用的元件未达到液化石油气的使用标准。如果使用了正确的加热系统,同时向导能够根据安全预防常识及时观察到易燃燃料的状况,那么这起事故是完全可以避免的。本文阐述了对此事故的调查,并希望提醒船只使用者和海洋专业人员能明白使用非标准燃油输运元件的内在危险性。

关键词：液化石油气火灾事故调查

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Comprehensive Euler/Lagrange modelling including particle erosion for confined gas-solid flows

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Particuology 2024年第1期84卷 209-235页

作者： Guiherme A.Novelletto Ricardo martin Sommerfeld Multiphase Flow Systems Institute of Process EngineeringOtto-von-Guericke-University MagdeburgHoher Weg 7b06120Halle(Saale)Germany

The present research aims to assess the capability of a comprehensive Euler/Lagrange approach for predicting gas-solid flows and the associated solid particle *** open-source code OpenFOAM®4.1 was used to carry out the numerical simulations,where the standard Lagrangian libraries were substantially extended to account for all necessary *** are tracked considering both translational and rotational motion as well as all relevant forces,such as gravity/buoyancy,drag and transverse lift due to shear and particle *** tracking time step was dynamically adapted ac-cording to the locally relevant time scales,which drastically reduces computational *** approaches are adopted to model particle turbulent dispersion,particle collisions with rough walls and particle-particle *** solid particle erosion models,available in the literature,were considered to estimate pipe bend *** study cases are provided to validate the adopted nu-merical approach and erosion models *** first case intends to evaluate the ability of the extended CFD code to predict the behaviour of gas-solid flows in pneumatic conveying *** goal is achieved by comparing the numerical results with the experimental data obtained by Huber(1997)and Huber and Sommerfeld(1994,1998)in a pneumatic conveying ***,the importance of considering inter-particle collisions and surface roughness for predicting particle velocity,mass flux and mean diameter distributions in gas-solid flows is *** second and third case intend to evaluate the ability of the erosion models in estimating bend erosion in diluted gas-solid *** erosion data obtained experimentally by Mazumder et al.(2008)and Solnordal et al.(2015)in very dilut pneumatic conveying systems is used for validating the numerical results,neglecting now inter-particle collisions and two-way *** a comprehensive analysis of the different influential properti

关键词： Pneumatic conveying Pipe bend Numerical calculation(CFD) Euler/Lagrange approach Erosion models Wall roughness

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