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中国畜牧杂志 2008年第24期44卷 49-50页

作者：王志博 alberto gimeno 北京库德商贸有限公司北京100096

巴西是世界上最大的谷物生产国和禽、猪肉的出口国之一。在霉菌毒素问题解决上,他们又为全世界做了表率。相比而言,在目前资源相对短缺的情况下,如何对原料加以善用,值得我们深思。

关键词：霉菌毒素巴西甘蔗生产玉米生产食品价格乙醇饲料

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霉菌毒素对奶牛的不良影响

中国乳业 2010年第7期 34-37页

作者： alberto gimeno 王琦任东东卫麦霞郭万库美国特殊营养品公司深圳市赛斯特农业发展有限公司

霉菌毒素是由一些产毒霉菌菌株产生的有毒次级代谢产物。具体来说,霉菌毒素是在特定的物理、化学及生物条件下产生于缩合反应的多酮化合物,这个过程由霉菌来完成,它发生在当脂肪酸生物合成过程中酮组不再减少时。这些脂肪酸是一种被霉... 详细信息

霉菌毒素是由一些产毒霉菌菌株产生的有毒次级代谢产物。具体来说,霉菌毒素是在特定的物理、化学及生物条件下产生于缩合反应的多酮化合物,这个过程由霉菌来完成,它发生在当脂肪酸生物合成过程中酮组不再减少时。这些脂肪酸是一种被霉菌用作能源的初级代谢物。霉菌毒素通常形成于霉菌生长的对数生长阶段后期或平稳增长阶段的初期。霉菌毒素引起人类和动物的疾病和紊乱,被称为霉菌毒素中毒症。

关键词：霉菌毒素奶牛次级代谢产物对数生长阶段缩合反应合成过程霉菌生长脂肪酸

The Role of the Solar Cycle in the Relationship Between the North Atlantic Oscillation and Northern Hemisphere Surface Temperatures

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Advances in Atmospheric Sciences 2007年第2期24卷 191-198页

作者： Laura DE LA TORRE Luis gimeno Juan Antonio AEL Raquel NIETO Universidad de Vigo Facultad de Ciencias de Ourense 32004OurenseSpain

The North Atlantic Oscillation （NAO） is one of the leading modes of climate variability in the Northern Hemisphere. It has been shown that it clearly relates to changes in meteorological variables, such as surface temperature, at hemispherical scales. However, recent studies have revealed that the NAO spatial pattern also depends upon solar forcing. Therefore, its effects on meteorological variables must vary depending upon this factor. Moreover, it could be that the Sun affects climate through variability patterns, a hypothesis that is the focus of this study. We find that the relationship between the NAO/AO and hemispheric temperature varies depending upon solar activity. The results show a positive significant correlation only when solar activity is high. Also, the results support the idea that solar activity influences tropospheric climate fluctuations in the Northern Hemisphere via the fluctuations of the stratospheric polar vortex .

关键词： solar activity North Atlantic Oscillation Arctic Oscillation Northern Hemisphere surface temperature

Variations of OCT measurements corrected for the magnification effect according to axial length and refractive error in children

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Journal of Innovative Optical Health Sciences 2018年第1期11卷 123-137页

作者： Inmaculada Bueno-gimeno Enrique España-Gregori Andres Gene-Sampedro Juan Carlos Ondategui-Parra Carlos J.Zapata-Rodriguez Department of Optics and Optometry and Vision Science University of Valencia Spain Department of Surgery University of Valencia University Hospital La FeSpain Faculty of Optics and Optometry University Vision Centre Polytechnic University of CataloniaSpain

Purpose:The aim of this paper was to examine the distribution of macular,retinal nerve fiber layer(RNFL)thickness and optic disc parameters of myopic and hyperopic eyes in comparison withemmetropic control eyes and to investigate their variation according to axial length(AL)andspherical equivalent(SE)in healthy ***:This study included 293 pairs of eyes of 293children(145 boys and 148 girks),ranging in age from 6 to 17 years,Subjects were dividedaccording to SE in control(emmetropia,99 children),myopia(100 children)and hyperopia(94children)groups and according to axial AL in 68 short(25.00 mm,36).Macular parameters,RNFL thickness and opticdisc morphology were assessed by the Cirrus^(TM) *** was measured using the ***'s formula was used for calculating the corrected AL-related ocular *** Mean age(±SD)was 10.84±3.05 years;mean(±SD)SE was+0.14±0.51 D(range from8.75 to+8.25 D)and mean AL(±SD)was 23.12±*** RNFL thickness,averagemacular thickness and macular volume decreased as AL and myopia *** correlationsbetween AL/SE and optic disc parameters were found after correcting for magnification ***:AL and refractive error affect measurements of macular and RNFL thickness inhealthy *** make a correct interpretation of ocT measurements,ocular magnificationeffect should be taken into account by clinicians or OCT manufacturers.

关键词： Axial length refractive error children OCT measurements magnification fect

ABA-Mediated Inhibition of Germination Is Related to the Inhibition of Genes Encoding Cell-Wall Biosynthetic and Architecture： Modifying Enzymes and Structural Proteins in Medicago truncatula Embryo Axis

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Molecular Plant 2009年第1期2卷 108-119页

作者： Christine gimeno-Gilles Eric Lelievre Laure Viau Mustafa Malik-Ghulam Claudie Ricoult Andreas Niebel Nathalie Leduc Anis M. Limami University of Angers UMR_A 1191 Physiologie Moleculaire des Semences (PMS) 2 Bd Lavoisier F-49045 Angers France UMR 441 CNRs-INRA Laboratoire de Biologie Moleculaire des Relations Plantes Micro-organismes (LIPM) Castanet-Tolosan 31326 cedex France University of Angers UMR Sciences Agronomiques Appliques a I'Horticulture (SAGAH) 2 Bd Lavoisier F-49045 Angers France

Radicle emergence and reserves mobilization are two distinct programmes that are thought to control germination. Both programs are influenced by abscissic acid （ABA） but how this hormone controls seed germination is still poorly known. Phenotypic and microscopic observations of the embryo axis of Medicago truncatula during germination in mitotic inhibition condition triggered by 10 μM oryzalin showed that cell division was not required to allow radicle emergence. A suppressive subtractive hybridization showed that more than 10% of up-regulated genes in the embryo axis encoded proteins related to cell-wall biosynthesis. The expression of α-expansins, pectin-esterase, xylogucan-endotransglycosidase, cellulose synthase, and extensins was monitored in the embryo axis of seeds germinated on water, constant and transitory ABA. These genes were overexpressed before completion of germination in the control and strongly inhibited by ABA. The expression was re-established in the ABA transitory-treatment after the seeds were transferred back on water and proceeded to germination. This proves these genes as contributors to the completion of germination and strengthen the idea that cell-wall loosening and remodeling in relation to cell expansion in the embryo axis is a determinant feature in germination. Our results also showed that ABA controls germination through the control of radicle emergence, namely by inhibiting cell-wall loosening and expansion.

关键词： ABA cell-wall expansion germination Medicago truncatula radicle emergence XET.

The timing of bowel preparation before colonoscopy determines the quality of cleansing,and is a significant factor contributing to the detection of flat lesions:A randomized study

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World Journal of Gastroenterology 2006年第38期12卷 6161-6166页

作者： Adolfo Parra-Blanco David Nicolás-Pérez Antonio gimeno-García Begoa Grosso Alejandro Jiménez Juan Ortega Enrique Quintero Department of Gastroenterology Hospital Universitario de Canarias La Laguna 38109 Santa Cruz de Tenerife Spain Research Unit Hospital Universitario de Canarias La Laguna 38109 Santa Cruz de Tenerife Spain

AIM： To compare the cleansing quality of polyethylene glycol electrolyte solution and sodium phosphate with different schedules of administration, and to evaluate whether the timing of the administration of bowel preparation affects the detection of polyps. METHODS： One hundred and seventy-seven consecutive outpatients scheduled for colonoscopy were randomized in one of four groups to receive polyethylene glycol electrolyte solution or oral sodium phosphate with two different timing schedules. Quality of cleansing, polyp detection, and tolerance were evaluated. RESULTS： Patients receiving polyethylene glycol or sodium phosphate on the same day as the colonoscopy, obtained good to excellent global cleansing scores more frequently than patients who received polyethylene glycol or sodium phosphate on the day prior to the procedure （P 〈 0.001）. Flat lesions, but not fiat adenomas, were more frequent in patients prepared on the same day （P = 0.02）. CONCLUSION： The quality of colonic cleansing and the detection of fiat lesions are significantly improved when the preparation is taken on the day of the colonoscopy.

关键词： Colonoscopy Preparation Polyp Flat lesion Sodium phosphate Polyethylene glycol

Miliary tuberculosis infection during hepatitis C treatment with sofosbuvir and ledipasvir plus ribavirin

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World Journal of Hepatology 2017年第3期9卷 161-166页

作者： Maria Pilar Ballester-Ferré Fernando Martínez Natalia Garcia-gimeno Francisco Mora Miguel A Serra Gastroenterology and Hepatology Department University Clinic Hospital of Valencia University of Valencia Digestive Medicine Department University Clinic Hospital of Valencia University of Valencia Internal Medicine Department University Clinic Hospital of Valencia University of Valencia

Chronic hepatitis C virus(HCV) infection is one of the main causes of chronic liver disease worldwide. In the last 5 years, treatment for HCV infection has experienced a marked development. In 2014, the use of ledipasvir/sofosbuvir with or without concomitant weight-based ribavirin was approved with a very significant increase in the sustained virological response. However, new side effects have been associated. We report the first case of an HCV infected patient treated for 12 wk with the combination of sofosbuvir/ledipasvir plus ribavirin who developed a miliary tuberculosis(TB) infection while on therapy. The patient was a 65-year-old woman, who referred malaise, asthenia, hyporexia, 7 kg weight loss, productive cough, evening fever and night sweats, right after finishing the treatment. The chest computed tomography-scan revealed a superior mediastinal widening secondary to numerous lymphadenopathies with extensive necrosis and bilateral diffuse lung miliary pattern with little subsequent bilateral pleural effusion, highly suggestive of lymph node tuberculosis with lung miliary spread. A bronchoscopy was performed and bronchial suction showed more than 50 acid-alcohol resistant bacillus per line. A Mycobacterium tuberculosis DNA was detected in blood by polymerase chain reaction, which confirmed the diagnosis of miliary tuberculosis. Some cases of TB infection have been identified with α-interferon-based therapy and with the triple therapy of pegylated interferon, ribavirin and boceprevir or telaprevir. However, significant infection has not been reported with sofosbuvir/ledipasvir plus *** believe that the case is relevant to increase awareness of opportunistic infections and particularly TB infection. Although the international guidelines offer no recommendation regarding TB screening, we wonder whether it would be advisable to screen for opportunistic infections prior to the introduction of HCV therapy.

关键词： Tuberculosis Ledipasvir Ribavirin Sofosbuvir Hepatitis C

Estimation of mean water vapour residence time during tropical cyclones using a Lagrangian approach

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Tropical Cyclone Research and Review 2022年第2期11卷 76-87页

作者： Albenis Perez-Alarcon Patricia Coll-Hidalgo Jose C.Fernandez-Alvarez Raquel Nieto Luis gimeno Centro de Investigacion Marina Universidade de VigoEnvironmental Physics Laboratory(EPhysLab)OurenseSpain Departamento de Meteorología Instituto Superior de Tecnologías y Ciencias AplicadasUniversidad de La HabanaLa HabanaCuba Departamento de Meteorología Empresa Cubana de Navegacion AereaLa HabanaCuba

Tropical cyclone(TC)-related rainfall mostly depends on the atmospheric moisture uptake from local and remote *** this study,the mean water vapour residence time(MWVRT)was computed for precipitation related to TCs in each basin and on a global scale by applying a Lagrangian moisture source diagnostic *** to our results,the highest MWVRT was found for the TCs over the South Indian Ocean and South Pacific Ocean basins(~3.08 days),followed by the Western North Pacific Ocean,Central and East North Pacific Ocean,North Indian Ocean,and North Atlantic Ocean basins(which exhibited values of 2.98,2.94,2.85,and 2.72 days,respectively).We also found a statistically significant(p<0.05)decrease in MWVRT,at a rate of~2.4 h/decade in the North Indian Ocean and~1.0 h/decade in the remaining *** average,the MWVRT decreased during the 24 h before TCs made landfall,and the atmospheric parcels precipitated faster after evaporation when TCs moved over land than over the *** research should focus on the relationship between global warming and MWVRT of atmospheric parcels that precipitate over TC positions.

关键词： Tropical cyclones Water vapour residence time Lagrangian approach Tropical cyclones precipitation

Insights into the origin of precipitation moisture for tropical cyclones during rapid intensification process

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Tropical Cyclone Research and Review 2024年第2期13卷 72-87页

作者： Albenis Perez-Alarcon Jose C.Fernandez-Alvarez Ricardo M.Trigo Raquel Nieto Luis gimeno Centro de Investigacion Mari~na Universidade de VigoEnvironmental Physics Laboratory(EPhysLab)Campus As Lagoas s/nOurenseSpain Departamento de Meteorología Instituto Superior de Tecnologías y Ciencias AplicadasUniversidad de La HabanaLa HabanaCuba Instituto Dom Luiz(IDL) Facultade de Ci^enciasUniversidade de LisboaLisboaPortugal Departamento de Meteorologia Universidade Federal do Rio de JaneiroRio de JaneiroBrazil

In this study,we identiﬁed the moisture sources for the precipitation associated with tropical cyclones(TCs)during the rapid intensiﬁcation(RI)process from 1980 to 2018 by applying a Lagrangian moisture source diagnostic *** detected sixteen regions on a global scale for RI events distributed as follows:four in the North Atlantic(NATL),two in the Central and East Paciﬁc Ocean(NEPAC),the North Indian Ocean(NIO)and South Indian Ocean(SIO),and three in the South Paciﬁc Ocean(SPO)and the Western North Paciﬁc Ocean(WNP).The moisture uptake(MU)mostly was from the regions where TCs underwent *** Western NATL,tropical NATL,Caribbean Sea,the Gulf of Mexico and the Central America and Mexico landmass supported~85.4%of the precipitating moisture in the NATL,while the latter source and the eastern North Paciﬁc Ocean provided the higher amount of moisture in NEPAC(~84.3%).The Arabian Sea,the Bay of Bengal and the Indian Peninsula were the major moisture sources in NIO,contributing approximately 81.3%.The eastern and western parts of the Indian Ocean supplied most of the atmospheric humidity in SIO(~83.8%).The combined contributions(~87.9%)from the western and central SPO and the Coral Sea were notably higher in ***,TCs in the WNP basin mostly received moisture from the western North Paciﬁc Ocean,the Philippine Sea and the China Sea,accounting for 80.1%.The remaining moisture support in each basin came from the summed contributions of the remote ***,RI TCs gained more moisture up to 2500 km from the cyclone centre than those slow intensiﬁcation(SI)and the total MU was approximately three times higher during RI than ***,the patterns of the MU differences respond to the typical pathways of moisture transport in each basin.

关键词： Tropical cyclones Rapid intensiﬁcation Moisture sources Precipitation Lagrangian moisture tracking

Recent advances in bird sperm morphometric analysis and its role in male gamete characterization and reproduction technologies

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Asian Journal of Andrology 2016年第6期18卷 882-888页

作者： Julian Santiago-Moreno Milagros Cristina Esteso Silvia Villaverde-Morcillo Adolfo Toledano-Diaz Cristina Castafio Rosario Velazquez Antonio Lopez-Sebastian Agustin Lopez Goya Javier gimeno Martinez Department of Animal Reproduction INIA 28040 Madrid Spain Veterinary Clinical and Research Services Fieb Foundation 28760 Tres Cantos Madrid Spain FAUNIA 28032 Madrid Spain

Postcopulatory sexual selection through sperm competition may be an important evolutionary force affecting many reproductive traits, including sperm morphometrics. Environmental factors such as pollutants, pesticides, and climate change may affect different sperm traits, and thus reproduction, in sensitive bird species. Many sperm-handling processes used in assisted reproductive techniques may also affect the size of sperm cells. The accurately measured dimensions of sperm cell structures （especially the head） can thus be used as indicators of environmental influences, in improving our understanding of reproductive and evolutionary strategies, and for optimizing assisted reproductive techniques （e.g., sperm cryopreservation） for use with birds. Computer-assisted sperm morphometry analysis （CASA-Morph） provides an accurate and reliable method for assessing sperm morphometry, reducing the problem of subjectivity associated with human visual assessment. Computerized systems have been standardized for use with semen from different mammalian species. Avian spermatozoa, however, are filiform, limiting their analysis with such systems, which were developed to examine the approximately spherical heads of mammalian sperm cells. To help overcome this, the standardization of staining techniques to be used in compute^-assessed light microscopical methods is a priority. The present review discusses these points and describes the sperm morphometric characteristics of several wild and domestic bird species.

关键词： avian computer-assisted assay morphometry spermatozoa