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Heterosis of Vine Decline Disease Resistance Caused by the Fungus Monosporascus cannonballus in Melons (Cucumis melo L)

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Agricultural Sciences 2023年第5期14卷 629-635页

作者： Sixto Alberto MARQUEZ John Jifon Kevin Michael Crosby Carlos Augusto Avila Amir Mohamed Hussein Ibrahim Department of Horticultural Sciences Texas A & M University College Station Texas United States Vegetable & Fruit Improvement Center Department of Horticultural Sciences Texas A & M University College Station Texas United States USDA National Center of Excellence for Melon at The Vegetable and Fruit Improvement Center of Texas A & M University College Station Texas United States Texas A & M AgriLife Research and Extension Center at Weslaco Texas United States Department of Soil and Crop Sciences Texas A & M University Texas United States

Vine decline disease (VDD) constitutes a menace to melons worldwide. Especially, the one caused by the fungus Monosporascus cannonballus. Thus, resistant plant material must be released to help growers. Hence, our goal was to develop resistant plant material to VDD. More than 600 melon accessions are expected to be tested for disease resistance in M. cannonballus infested soil in Weslaco, Texas, USA, to identify resistance to VDD, and other important traits. So far, at most 7 lines were found to be resistant to VDD and some of them were used to develop elite, muskmelon inbred lines by pedigree breeding following single or double backcrosses. These elite parents were crossed to each other to develop the hybrids M3 and M4. They were also tested in the same infested field in Weslaco. The hybrids were grown using standard commercial practices followed by growers and when their fruits were ready, their roots were sampled as well as scored for disease severity to estimate high and mid-parent heterosis Our results indicate the existence of heterosis regarding resistance to VDD. Thus, resistant plant material can be developed and selection for resistance can be accomplished.

关键词： Melons Vine Decline Disease Monosporascus cannonballus Resistance Heterosis

Two novel mutations in theGAN gene causing giant axonal neuropathy

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World Journal of Pediatrics 2018年第3期14卷 298-304页

作者： Monica Irad Normendez-Martínez Lucero Monterde-Cruz Roberto Martínez Magdalena marquez-Harper Nayelli Esquitin-Garduno Margarita Valdes-Flores Leonora Casas-Avila Valeria Ponce de Leon-Suarez Viktor Javier Romero-Díaz alberto Hidalgo-Bravo Medical Specialties Hospital Boulevard Milenio 130San Carlos la Roncha37660 LeonGuanajuatoMexico Department of Gene tics National Institute of R ehabilitationAvenue Mexico-Xochimilco 28914389 Me xico CityMexico Department ofHis tology School ofMedicineAutonomous University oft heS tate ofN uevo LeonMonterreyMexico

Background Giant axonal neuropathy (GAN) is a rare neurodegenerative disease transmitted in an autosomal recessive mode. This disorder presents motor and sensitive symptoms with an onset in early childhood. Progressive neurodegeneration makes the patients wheelchair dependent by the end of the second decade of life. Affected individuals do not survive beyond the third decade of life. Molecular analysis has identified mutations in the gene GAN in patients with this disorder. This gene produces a protein called gigaxonin which is presumably involved in protein degradation via the ubiquitin-proteasome system. However, the underlying molecular mechanism is not clearly understood yet. Methods Here we present the fi rst patient from Mexico with clinical data suggesting GAN. Sequencing of the GAN gene was carried out. Changes in the nucleotide sequence were investigated for their possible impact on protein function and structure using the publicly available prediction tools PolyPhen-2 and PANTHER. Results The patient is a compound heterozygous carrying two novel mutations in the GAN gene. The sequence analy-sis revealed two missense mutations in the Kelch repeats domain. In one allele, a C>T transition was found in exon 9 at the nucleotide position 55393 (g.55393C>T). In the other allele, a transversion G>T in exon 11 at the nucleotide position 67471 (g.67471G>T) was observed. Both of the bioinformatic tools predicted that these amino acid substitutions would have a negative impact on gigaxonin's function. Conclusion This work provides useful information for health professionals and expands the spectrum of disease-causing mutations in the GAN gene and it is the first documented case in Mexican population.

关键词： GAN Genetics Giant axonal neuropathy Incapacity Neurodegenerative

Time-domain terahertz spectroscopy in high magnetic fields

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Frontiers of Optoelectronics 2021年第1期14卷 110-129页

作者： Andrey BAYDIN Takuma MAKIHARA Nicolas marquez PERACA Junichiro KONO Department of Electrical and Computer Engineering Rice UniversityHoustonTX 70005USA Department of Physics and Astronomy Rice UniversityHoustonTexas 77005USA Department of Materials Science and NanoEngineering Rice UniversityHoustonTexas 77005USA

There are a variety of elementary and collective terahertz-frequency excitations in condensed matter whose magnetic field dependence contains significant insight into the states and dynamics of the electrons involved.Often,determining the frequency,temperature,and magnetic field dependence of the optical conductivity tensor,especially in high magnetic fields,can clarify the microscopic physics behind complex many-body behaviors of solids.While there are advanced terahertz spectroscopy techniques as well as high magnetic field generation techniques available,a combination of the two has only been realized relatively recently.Here,we review the current state of terahertz time-domain spectroscopy(THz-TDS)experiments in high magnetic fields.We start with an overview of time-domain terahertz detection schemes with a special focus on how they have been incorporated into optically accessible high-field magnets.Advantages and disadvantages of different types of magnets in performing THz-TDS experiments are also discussed.Finally,we highlight some of the new fascinating physical phenomena that have been revealed by THz-TDS in high magnetic fields.

关键词： high magnetic field terahertz time-domain spectroscopy(THz-TDS)

The power of“touch”and early enriched stimulation:neuroplasticity effects in rodents and preterm infants

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Neural Regeneration Research 2022年第6期17卷 1248-1250页

作者： alberto Fernández-Teruel Department of Psychiatry and Forensic Medicine&Institute of Neurosciences School of MedicineAutonomous University of BarcelonaBellaterraBarcelonaSpain

Early postnatal stimulation,e.g.,neonatal handling(NH)in its most frequent form,and environmental enrichment(EE,the exposure of juvenile animals,usually during several weeks,to environments involving rich and variable sensory stimulation)produce profound and long-lasting behavioral and neurobiological effects.Both treatments reduce anxiety and stress sensitivity,and improve neurodevelopment and learning/memory in unconditioned and conditioned tasks in laboratory rodents.

关键词： stimulation neonatal enriched

光学相干断层成像评估高血压性视网膜病变神经元损伤应用价值的研究

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中国全科医学 2024年第9期27卷 1082-1087页

作者：赵润泽孙小佳 Melba marquez Hernandez 窦国睿空军军医大学西京医院眼科、全军眼科研究所陕西省西安市710032 Lázaro#701 esq.a Belascoaín Centro HabanaLa HabanaCuba.Hospital Clínico Quirúrgico“Hermanos Ameijeiras”(HHA)Calle San 10400Cube

背景当前高血压的患病率呈逐年增长趋势,其眼部并发症高血压视网膜病也日益受到关注。然而目前对于高血压性视网膜病变中神经元损伤的研究尚少。目的本研究以光学相干断层成像检查为检查手段,探究其在高血压性视网膜病变中神经元损伤评... 详细信息

背景当前高血压的患病率呈逐年增长趋势,其眼部并发症高血压视网膜病也日益受到关注。然而目前对于高血压性视网膜病变中神经元损伤的研究尚少。目的本研究以光学相干断层成像检查为检查手段,探究其在高血压性视网膜病变中神经元损伤评估中的应用和重要价值。方法纳入2019年3月—2020年7月于Hospital Clínico Quirúrgico“Hermanos Ameijeiras”(HHA医院)就诊的102例高血压患者为研究对象,同时纳入45名健康受试者,监测24 h动态血压,取24 h舒张压和收缩压的平均动脉血压值,测量眼压,计算眼灌注压。检测视盘区视网膜神经纤维(RNFL)厚度和黄斑区神经节细胞复合层(GCC)厚度。依据血压控制情况将患者分为血压控制组(n=51)和血压未控制组(n=51),45名健康受试者为对照组。采用Pearson相关性分析或Spearman秩相关分析探究血压、眼灌注压、视网膜病变与GCC厚度和血压、眼灌注压与视网膜病变的相关性,采用R 3.5.3软件进行中介作用分析。结果3组研究对象人种、收缩压、舒张压、平均动脉压、眼压、眼灌注压、视网膜病变比较,差异有统计学意义(P<0.05)。血压未控制组平均RNFL厚度低于对照组(P<0.05),血压控制组、血压未控制组GCC平均厚度低于对照组,血压未控制组GCC最小值低于对照组(P<0.05)。相关性分析结果显示,GCC平均厚度、上方GCC厚度、颞下方CCG厚度与收缩压、舒张压、眼灌注压、视网膜病变呈负相关(P<0.05),颞上方GCC厚度与收缩压、舒张压、眼灌注压呈负相关(P<0.05),下方GCC厚度与舒张压呈负相关(P<0.05),视网膜病变与收缩压、舒张压、眼灌注压呈正相关(P<0.05)。中介效应结果显示,“收缩压→GCC平均厚度→高血压性视网膜病变”效应显著,收缩压与GCC平均厚度呈正相关,GCC平均厚度与高血压性视网膜病变呈正相关(P<0.05)。收缩压对高血压性视网膜病变发生风险具有直接影响(β=0.013,95%CI=0.007~0.020,P<0.001),GCC平均厚度部分介导了收缩压对高血压性视网膜病变发生风险的影响(β=0.117,95%CI=0.014~0.360,P=0.04),中介效应占总效应的11.7%。结论光学相干断层成像检查是一种无创的眼科检查方法,可优于普通眼底检查提前发现高血压性视网膜神经元受损情况,对高血压导致视神经受损的不可逆盲和高血压靶器官受损进行早期预防和预警。

关键词：高血压性视网膜病变高血压光学相干断层成像术神经纤维中介分析

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中国对外直接投资对委内瑞拉经济的影响

中国对外直接投资对委内瑞拉经济的影响

作者： Servio marquez 东北财经大学

学位级别：硕士

先前的调查已经通过对委内瑞拉和中国外交关系的分析探讨了两国之间的关系,其他的一些调查通过提供丰富的关于委内瑞拉每年石油产量(以桶计算)极其利润的数据,向我们表明了在这个领域上研究所取得的巨大进步。这个研究做出了对加勒比海... 详细信息

先前的调查已经通过对委内瑞拉和中国外交关系的分析探讨了两国之间的关系,其他的一些调查通过提供丰富的关于委内瑞拉每年石油产量(以桶计算)极其利润的数据,向我们表明了在这个领域上研究所取得的巨大进步。这个研究做出了对加勒比海国家和中国社会经济现状方面准确的理论预测,表明由于一系列委内瑞拉政府不英明的决定而造成的国内经济现状和不完善的行业发展阻止了亚洲国家在其经济繁荣期一成指数增长时,去投资曾经经济最强大的拉丁美洲国家。正是通过大量相关的分析,得出了对中国投资拉丁美洲国家有影响的因素,更准确的说研究其实是以委内瑞拉国内最大公因子(GCF)为主要变量,并以国家外债和国内生产总值(GDP)为第二主要变量。上述分析是基于2009-2013年的月数据进行的,为了确保准确性,还对数据做出了相应的季节性调整。统计结果证明委内瑞拉的经济很显著地受到中国外国直接投资(FDI)的影响。

关键词：中国委内瑞拉外国直接投资(FDI) 经济关系

基于退化状态确定旋转设备剩余使用寿命的模型

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Journal of Central South University 2020年第8期27卷 2291-2310页

作者： Saeed RAMEZANI Alireza MOINI Mohamad RIAHI Adolfo Crespo marquez Department of Industrial Engineering Iran University of Science and TechnologyTehranIran Department of Mechanical Engineering Iran University of Science and TechnologyTehranIran Department of Industrial Management University of SevilleSpain

状态评估是设备健康管理的重要技术之一。PHM方法周期是CBM的一种发展形式,而条件评估是其中最重要的步骤。本文结合传感器信息、降解状态的确定和健康指标的预测,计算了设备的剩余使用寿命。利用一种确定Demster-Shafer组合规则概率的... 详细信息

状态评估是设备健康管理的重要技术之一。PHM方法周期是CBM的一种发展形式,而条件评估是其中最重要的步骤。本文结合传感器信息、降解状态的确定和健康指标的预测,计算了设备的剩余使用寿命。利用一种确定Demster-Shafer组合规则概率的新方法和模糊c均值聚类方法对传感器信息进行组合。利用自回归马尔可夫状态转换(ARMR)方法对提取的基于振动的健康指数进行模拟和预测,确定最终的健康状态,估计剩余寿命(RUL)。为了对模型进行评价,使用了FEMTO-ST研究所提供的传感器数据。

关键词：剩余使用寿命预后与健康管理自回归马尔可夫状态转换健康指数(HI) Dempster-Shafer理论模糊c均值法 Kurtosis-entropy 退化

共生知识的创造：可可轨迹的灵活性、流动性和异质性实践

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共生知识的创造：可可轨迹的灵活性、流动性和异质性实践

作者： Rosangela marquez Gallegos 华东师范大学

学位级别：硕士

This study is intended to demonstrate how the assembly within multiple knowledge of what is local and global,can be connected and disconnected by its participantsBased on Venezuela and China one of the traj ectories to be taken in this research,and to which I want to focus my fieldwork,is the practice of cacao,but the cacao considered as consumption,as a final product for sensorial appreciation.Along with this perception,the complex process of production,exists and create a set of edges that question many aspects of practices around cacao,which goes from the soil to that smelling bar,with a characteristic color that we consider as chocolate.Taking into account this multiplicity of meanings that can be generated based on this circuit,during the fieldwork that I demonstrate here,I proposed how on this huge assemblage between two countries,can be generated a whole circuit of meanings,production of knowledge,malleability on their practices and even a flexibility in their own identity inside this transnational flow.

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History and recent progress in ferroelectrets produced in Brazil

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Journal of Advanced Dielectrics 2023年第4期13卷 27-34页

作者： Ruy alberto Pisani Altafim Ruy alberto Corrêa Altafim Computer Systems Department Informatics CenterFederal University of Paraíba João PessoaPBBrazil Electrical and Computer Department University of São PauloSão CarlosSPBrazil

More than 30 years ago,a group of researchers in Tampere-Finland developed a thin foamed polymeric material for capacitive sensors.Such soft-voided films exhibited electrical charging characteristics,forming a powerful combination,which resulted in a smart-material with ferroelectric properties.The discovery of the electro-thermo mechanical film(ETMF)has sparked the curiosity of the electret community,leading to the development of several studies.At that time,ETMF became known as cellular electrets and,later,as ferroelectrets or piezoelectrets regarding their electromechanical properties.This paper provides a timeline review of the research on ferroelectrets produced in Brazil,between the years 1990 and 2020,towards demonstrating how the interest in the electret electrical charging mechanism has resulted in the use of ferroelectrets with well-controlled cavities for ultrasound applications.

关键词： Cellular electrets piezoelectrets ferroelectrets electromechanical films.