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World Journal of Gastroenterology 2007年第31期13卷 4224-4229页

作者： Perdita Wietzke-braun Larissa bettina Mnhardt albert Rosenberger Angela Uy Giuliano Ramadori sabine Mihm Department of Gastroenterology and Endocrinology Robert-Koch-Str.40 37075 Gttingen Germany Department of Genetic Epidemiology Humboldtallee 32 Gttingen 37073 Germany Department of Microbiology Kreuzbergring 57 Gttingen Georg-August-Universitt Gttingen 37075 Germany

To find correlates to spontaneous clearance of hepatitis C virus （HCV） infection, this study compared individuals with self-limited and chronic infection with regard to clinical, demographic, and serological pa- rameters. METHODS： Sixty-seven anti-HCV positive and repeatedly HCV RNA negative individuals were considered to have resolved HCV infection spontaneously. To determine the viral genotype these patients had been infected with HCV serotyping was performed. For comparison reasons, 62 consecutive patients with chronic hepatitis C were enrolled. Cases and controls were compared stratified for age and sex. RESULTS： Retrospective analysis showed （1） a lower humoral reactivity to HCV in patients with self-limited compared to chronic HCV-infection and （2） that younger age, history of iv drug use, and acute/post-acute hepatitis A or b co-infections, but not viral genotypes, are independent correlates for spontaneous HCV clearance. CONCLUSION： The stronger humoral reactivity to HCV in patients with persistent infections and in those with a history of iv drug use is supposed to be due to continuous or repeated contact（s） to the antigen. Metachronous hepatitis A or hepatitis b infections might favor HCV clearance.

关键词： Hepatitis C virus Hepatitis Self-limitedinfection Anti-HCV antibodies Co-infection HCVserotype

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关于社区、场所营造和商业零售设计的思考

建筑实践 2023年第6期 6-19页

作者：陈建邦瑞安集团瑞安房地产规划发展部

伟大的城市是由伟大的社区构成的，并非建筑单体。打造一个伟大社区的关键，是拥有非凡活力的公共空间。商业零售则是营造公共空间活力的重要“催化剂”。然而，目前很多中国城市都存在商业过剩的问题，大部分商业空间也没有发挥其对于...

伟大的城市是由伟大的社区构成的，并非建筑单体。打造一个伟大社区的关键，是拥有非凡活力的公共空间。商业零售则是营造公共空间活力的重要“催化剂”。然而，目前很多中国城市都存在商业过剩的问题，大部分商业空间也没有发挥其对于社区应有的作用。我们需要重新思考如何在设计中将商业零售和场所营造更为积极地结合在一起；同时，亦要保护焕新建筑遗产和满足可持续发展的要求。

关键词：

All-fiber ellipsometer for nanoscale dielectric coatings

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Opto-Electronic Advances 2023年第10期6卷 31-43页

作者： Jose Javier Imas Ignacio R.Matías Ignacio Del Villar Aritz Ozcáriz Carlos Ruiz Zamarreño Jacques albert Department of Electrical Electronic and Communications EngineeringPublic University of NavarrePamplona 31006Spain Institute of Smart Cities Public University of NavarrePamplona 31006Spain Department of Electronics Carleton UniversityOttawa(Ontario)K1S 5B6Canada.

Multiple mode resonance shifts in tilted fiber bragg gratings(TFbGs)are used to simultaneously measure the thickness and the refractive index of TiO_(2) thin films formed by Atomic Layer Deposition(ALD)on optical *** is achieved by comparing the experimental wavelength shifts of 8 TFbG resonances during the deposition process with simulated shifts from a range of thicknesses(T)and values of the real part of the refractive index(n).The minimization of an error function computed for each(n,T)pair then provides a solution for the thickness and refractive index of the deposited film and,a posteriori,to verify the deposition rate throughout the process from the time evolution of the wavelength shift *** of the results were carried out with a conventional ellipsometer on flat witness samples deposited simultaneously with the fiber and with scanning electron measurements on cut pieces of the fiber *** final values obtained by the TFbG(n=2.25,final thickness of 185 nm)were both within 4%of the validation *** approach provides a method to measure the formation of nanoscale dielectric coatings on fibers in situ for applications that require precise thicknesses and refractive indices,such as the optical fiber sensor ***,the TFbG can also be used as a process monitor for deposition on other substrates for deposition methods that produce uniform coatings on dissimilar shaped substrates,such as ALD.

关键词： tilted fiber bragg grating(TFbG) mode transition ellipsometer

牙源性透明细胞瘤——免疫组化及电镜研究(英文)

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口腔颌面外科杂志 2004年第1期14卷 60-62页

作者： Thomas albert Wei-Xiong Ye Monica b Zieper Charles K Meshul DepartmentofOralandMaxillofacialSurgery.SchoolofDentistryOregonHealthandScienceUniversity DepartmentofOralandMaxillofacialSurgery DepartmentofPathologyandRadiology DepartmentofPathologyandRadiology Pathology LaboratoryMedicineandResearchServicesPortlandVeteransAdministrationMedicalCenter

牙源性透明细胞瘤通常称牙源性透明细胞癌 ,是一种极少见的肿瘤。组织学上 ,肿瘤细胞排列成片状或巢状 ,细胞呈椭圆形或多边形 ,有丰富透明或淡伊红细胞浆和一小的偏中心 ,深染的核。偶尔肿瘤巢的周边细胞呈栅栏状排列和一反极向的核相... 详细信息

牙源性透明细胞瘤通常称牙源性透明细胞癌 ,是一种极少见的肿瘤。组织学上 ,肿瘤细胞排列成片状或巢状 ,细胞呈椭圆形或多边形 ,有丰富透明或淡伊红细胞浆和一小的偏中心 ,深染的核。偶尔肿瘤巢的周边细胞呈栅栏状排列和一反极向的核相似造釉细胞。大多数文献报道牙源性透明细胞瘤是一浸润性肿瘤。手术后 ,有复发倾向 ;常有区域及远处转移。因此 ,多数作者称此肿瘤为牙源性透明细胞癌。但是也有很多病例经长期随访 ,术后无复发 ,有随访长达 5a ,甚至用保守治疗(挖除肿瘤 )的病例 ,手术前已存 13a,手术时仅见局部膨胀和局部舌侧皮质骨板穿孔。术前及术后没有区域和远处转移。手术后已随访 5a。这些结果似指示这病例应属于良性肿瘤范畴。这种肿瘤是否有从良性到恶性的转变过程值得探讨。其显微镜所见 ,免疫组化及电子显微镜检查结果 ,不能与那些有恶性行为的肿瘤区别。因此 ,这些不能用作预测肿瘤的行为。作者主张整块肿瘤切除 ,术中做冰冻切片检查标本 ,以期获得无肿瘤残留的证据。

关键词：牙源性透明细胞瘤免疫组化电镜病理

Systematic overview of hepatitis C infection in the Middle East and North Africa

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World Journal of Gastroenterology 2018年第27期24卷 3038-3054页

作者： Karima Chaabna Sohaila Cheema Amit Abraham Hekmat Alrouh albert b Lowenfels Patrick Maisonneuve Ravinder Mamtani Institute for Population Health Weill Cornell Medicine-Qatar Department of Surgery and the Department of Family Medicine New York Medical College Division of Epidemiology and biostatistics European Institute of Oncology

AIM To assess the quality of and to critically synthesize the available data on hepatitis C infections in the Middle East and North Africa(MENA) region to map evidence *** We conducted an overview of systematic reviews(SRs) following an a priori developed protocol(CRD42017076736). Our overview followed the preferred reporting items for systematic reviews and metaanalyses guidelines for reporting SRs and abstracts and did not receive any funding. Two independent reviewers systematically searched MEDLINE and conducted a multistage screening of the identified articles. Out of 5758 identified articles, 37 SRs of hepatitis C virus(HCV) infection in populations living in 20 countries in the MENA region published between 2008 and 2016 were included in our overview. The nine primary outcomes of interest were HCV antibody(anti-) prevalences and incidences in different at-risk populations; the HCV viremic(RNA positive) rate in HCV-positive individuals; HCV viremic prevalence in the general population(GP); the prevalence of HCV co-infection with the hepatitis b virus, human immunodeficiency virus, or schistosomiasis; the HCV genotype/subtype distribution; and the risk factors for HCV transmission. The conflicts of interest declared by the authors of the SRs were also extracted. Good quality outcomes reported by the SRs were defined as having the population, outcome, study time and setting defined as recommended by the PICOTS framework and a sample size > *** We included SRs reporting HCV outcomes with different levels of quality and precision. A substantial proportion of them synthesized data from mixed populations at differing levels of risk for acquiring HCV or at different HCV infection stages(recent and prior HCV transmissions). They also synthesized the data over long periods of time(e.g., two decades). Anti-HCV prevalence in the GP varied widely in the MENA region from 0.1%(study dates not reported) in the United Arab Emirates to 2.1%-13.5%(2003-2006) in

关键词： Hepatitis C meta-research risk factors incidence genotype Middle East and North Africa systematic review Micro-elimination Pakistan Gulf Cooperation Council

^(123)I-bMIPP在犬顿抑心肌中的摄取、清除和代谢

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中华核医学杂志 2001年第3期21卷 143-146页

作者：曾骏 Lawrence H Young Jennifer Hu albert J Sinusas 上海市胸科医院核医学科 200030 美国耶鲁大学内科和诊断放射科

目的　利用12 3 I 15对碘苯基 3(R ,S)甲基十五烷酸 (bMIPP)在犬顿抑心肌 (SM)中的不匹配分布 ,探讨其作为诊断SM示踪剂的可能性。方法　建立标准犬左回旋支 (LCX)顿抑心肌模型(18min结扎后再灌注 ,n =12 )。监测血流动力学和心功能参... 详细信息

目的　利用12 3 I 15对碘苯基 3(R ,S)甲基十五烷酸 (bMIPP)在犬顿抑心肌 (SM)中的不匹配分布 ,探讨其作为诊断SM示踪剂的可能性。方法　建立标准犬左回旋支 (LCX)顿抑心肌模型(18min结扎后再灌注 ,n =12 )。监测血流动力学和心功能参数。Doppler探头测量LCX血流和局部室壁收缩厚度 (WT)。SPECT显像和组织γ计数法测量局部心肌的bMIPP、2 0 1Tl分布和微球灌注(RbF)。测量局部心肌耗氧量、葡萄糖和乳糖利用率。动态测量局部bMIPP摄取与清除。薄层层析法分析bMIPP及其代谢产物。结果　心肌顿抑时的血流动力学参数和冠状动脉血流恢复到基础水平 ,但WT明显低于基础值 [(12 .9± 2 9.1) %和 (6 6 .3± 2 2 .4) % ,P bMIPP[(70± 6 ) % ]高于2 0 1Tl[(6 6± 6 ) % ,P bMIPP[(88 5±6 0 ) % ]和Tl[(85 .4± 6 .7) % ]高于RbF[(70 .4± 10 .5 ) % ,P bF相关性较好(r=0 .6 7) ,而bMIPP与RbF不相关 (r=0 .11)。虽然SM的局部耗氧量和乳糖利用率低于基础值 ,但bMIPP代谢产物清除增加。未经代谢的bMIPP摄取和清除均有减低趋势。结论　代谢因素对SM的bMIPP残留有明显影响。

关键词：心肌缺血 ^123I-bMIPP 心肌顿抑摄取放射性核素显像清除代谢

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修缮江湾体育场,创建“创智天地”

时代建筑 2006年第2期49卷 72-75页

作者：陈建邦瑞安房地产发展有限公司

江湾体育场是创建“创智天地”不可或缺的一部分。文章剖析了保护并再利用江湾体育场对“创智天地”以及整个地区的重要意义。

关键词：修缮城市设计总体规划社区江湾体育场创智天地

Performance evaluation of residential buildings in public housing estates in 0gun State, Nigeria： Users＇ satisfaction perspective

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Frontiers of Architectural Research 2013年第2期2卷 178-190页

作者： Eziyi Offia Ibem Akunnaya P. Opoko albert b. Adeboye Dolapo Amole Department of Architecture Covenant University Ogun State 110001 Nigeria Department of Architecture Obafemi Awolowo University Osun State 220005 Nigeria

This study assessed the performance of residential buildings in public housing estates in urban areas of Ogun State Southwest Nigeria. It was based on the notion that users＇ satisfaction with dwelling units is a measure of the performance of residential buildings in meeting their needs and expectations. A cross sectional survey of 452 household heads in nine public housing estates was conducted in the study area. Data were obtained using structured questionnaire and observation schedule; and were subjected to descriptive statistics and factor analysis. A mean satisfaction score of 3.21 was observed; indicating that the respondents were generally satisfied with the performance of the different components of the buildings. Satisfaction levels were generally higher with privacy and sizes of living and sleeping areas than the availability of water and electricity in the buildings. The type, location and aesthetic appearance as well as size of main activity areas were the most predominant factors that determined satisfaction and indeed the performance of the buildings in meeting users＇ needs and expectations. The paper highlights critical areas where attention is needed in order to improve the performance of residential buildings and users＇ satisfaction with public housing projects in Nigeria.

关键词： buiLding performance User satisfaction Residential buildings Urban areas Ogun State

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筋会穴和井穴治疗颈部疼痛的临床研究

筋会穴和井穴治疗颈部疼痛的临床研究

作者：马青（Tania Calamardo albert）南京中医药大学

学位级别：硕士

研究目的对有太阳经络颈部疼痛的病人实施两种不同类型的治疗(一组和二组)。此次试验中的这两种类型的治疗组使用了同样的针灸穴位,但是我在治疗二组中添加了 4个新的穴位:筋会穴的阳经本神Gb 13和颧髎SI 18,还有井穴处的太阳经络少泽S... 详细信息

研究目的对有太阳经络颈部疼痛的病人实施两种不同类型的治疗(一组和二组)。此次试验中的这两种类型的治疗组使用了同样的针灸穴位,但是我在治疗二组中添加了 4个新的穴位:筋会穴的阳经本神Gb 13和颧髎SI 18,还有井穴处的太阳经络少泽SI 1和至阴bL67。观察并评估两种治疗组的临床疗效,对比两种疗法并总结两者之间是否有任何的不同疗效,从而为临床治疗所用。研究方法颈部疼痛现在在西班牙已经是一种非常普遍的问题,而且病人们一般都会选择去巴塞罗那的Fractal Studio Acupuncture诊所进行治疗所以我在那里参与了研究。大多数的治疗方法,我让他们去病人的家中。其余的治疗方法我可以在我的诊所做。整个研究都是以易于整合评估与比较治疗效果的为基础设计的。我一共治疗了 60例从门诊部选取的病人,同时将他们随机分为了每组30例病人的2个治疗组(一治疗组和二治疗组)。总的来选取的标准为不论性别同时拥有太阳处颈部疼痛症状病史的20到60岁的病人。除此之外的标准还会选取以下但不仅限于以下的病例:颈部骨折,椎基底动脉供血不足,颈脊髓癌,炎症或其它系统性疾病,和上颈椎韧带不稳[1]的病人。在实验研究中我将年龄、性别、疼痛等级和病程作为主要的变量。在实验研究中,我根据中西医之间的不同之处制定了诊疗的标准。由于太阳筋络的颈部疼痛可能由以上的任意病因造成,所以在这次实验研究中我决定将病因不同的影响排除在外,并专注于在对经络(太阳经络)的治疗研究上。此两种类型的治疗都将使用同样的针灸点但是我在治疗二组中添加了 4个穴位(筋会穴的本神Gb 13和颧髎SI18,太阳经络处井穴的少泽SI1和至阴bL 67)。每个病人都将接受10次治疗,一天一次每周5天。整个疗程总共2周。数据的收集开始于病人们的第一次来访时,使用V.A.S.疼痛等级评估让病人从1-10级中评估自己所处的疼痛等级。第一次记录于第一次治疗开始前,最后一次记录于第10次治疗结束后,以此来评估病人们的情况是否有好转。为了可以更加清晰和具体的描述结果,我设计了 4组治愈等级用来描述两治疗组的疗效(A,b,C,D级)其中A代表剩余疼痛等级为0即治愈,b代表疼痛等级降低了 5-9个等级即显效,C代表疼痛等级降低了2-4个等级即疗效有效,D代表疼痛等级降低了 0-1个等级即无效。描述性的数据被整理并用SPSS软件进行了分析,对年龄、病程、前疼痛V.A.S.等级和后V.A.S.疼痛等级使用了 T检验,对年龄使用了卡方分析。最后对两组治疗组的疗效等级的对比使用了秩和检验。研究结果在两组治疗前后在年龄、性别、病程及前疼痛等级上的差别并无统计学意义(P>0.05),所以说两组病例可以互相对比。通过T检验,两组病例在年龄上的差异并无统计学意义(t=0.178,P=0.859)。通过T检验,两组病例在病程上的差异并无统计学意义(t=1.050,P=0.301)。通过卡方分析,两组病例在年龄上的差异并无统计学意义(x2=0.067,P=0.796)。通过T检验,两组病例在前疼痛等级上的差异并无统计学意义(t=1.553,P=0.127)。在疗程结束后两组病例在V.A.S.疼痛等级上的差异并无统计学意义(P>0.05)。通过对比这两组病例,可以发现在疗程后的V.A.S.等级上两组病例并无统计学的意义(t=1.742,P=0.087)。通过秩和检验,两组治疗组的疗效等级上的差异并无统计学意义(Z=0.603,P=0.546)。研究结论两组治疗组同时对太阳处的颈部疼痛有着积极的疗效,在60例病人中达到C级有效(疼痛等级下降2-4个等级)的有39例。达到b级显效(疼痛等级下降了 5-9个等级)的病例数量占第二位,为13例。达到A级治愈(疼痛等级降为0等级)的病例数量与达到D级无效(疼痛等级下降了 0-1个等级)的病例数量一致,为4例.所以,两组病例同时都得到了有效的治疗。根据病例的治愈率来说治疗组一的结果稍好于治疗组二(治疗组一:96.67%的病例情况得到提高;治疗组二:90%的病例情况得到提高)。但根据统计学上的分析来看治疗组一和治疗组二在治疗效果上并不存在统计学上的差异(Z=0.603,P=0.546)。

关键词：筋会穴井穴太阳筋络颈部疼痛等级(V.A.S.scale of pain)

Superior mesenteric venous thrombosis: Endovascular management and outcomes

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World Journal of Clinical Cases 2022年第1期10卷 217-226页

作者： Khaled Alnahhal beau b Toskich Samuel Nussbaum Zhuo Li Young Erben albert G Hakaim Houssam Farres Department of Surgery Division of Vascular SurgeryMayo Clinic FloridaJacksonvilleFL 32224United States Department of Radiology Mayo Clinic FloridaJacksonvilleFL 32224United States Department of biostatistics Mayo Clinic FloridaJacksonvilleFL 32224United States

bACKGROUND Superior mesenteric venous thrombosis(SMVT)is a rare but fatal condition that is typically treated initially with anticoagulation therapy,and if this fails,with endovascular ***,due to its rarity,there are not many studies that have explored the effectiveness of anticoagulation and endovascular therapies in treating *** To evaluate patients diagnosed with SMVT who received endovascular therapy in addition to anticoagulation and report technical and clinical *** A retrospective analysis of the patients who underwent endovascular treatment for SMVT at Mayo Clinic from 2000-2019 was *** success was defined as angiographic improvement in SMV flow after *** patency was defined as the interval from reestablishing mesenteric venous flow until the first repeat thrombotic event or need for additional *** patency was defined as successful restoration of flow after repeat intervention until rethrombosis or last *** adverse events were reported through Clavien-Dindo *** Twenty-four patients were included for *** median age at intervention was 60 years(35-74 years)and 16(67%)were *** patients presented with acute thrombosis(79.2%)and 5 with chronic thrombosis with acute manifestations(20.8%).The most commonly used endovascular modalities were thrombectomy in 12 patients(50.0%)and catheter-directed thrombolysis in 10 patients(41.7%).Technical success was achieved in 18 patients(75%).The 14-d and 30-d primary patency rates were 88.9%and 83.3%,*** events were reported in two patients(8.3%),one marked as grade IIIb,and 1 death marked as grade ***-year overall survival rate was 82%(58%-100%).CONCLUSION Endovascular intervention with anticoagulation appears to be effective for managing *** treatment combination may be considered as first-line therapy for SMVT management in select patients.

关键词： Superior mesenteric venous thrombosis Endovascular Anticoagulation Retrospective Thrombectomy Mesenteric Thrombolysis