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A first assessment of Galapagos basidiolichens

Fungal Diversity 2012年第1期52卷 225-244页

作者： alba yánez Manuela Dal-Forno Frank Bungartz Robert Lücking James D.Lawrey Biodiversity Assessment Charles Darwin Foundation(AISBL)Puerto AyoraSanta CruzGalapagosEcuador Universidad Central del Ecuador QuitoEcuador Department of Environmental Science and Policy George Mason UniversityFairfaxVA 22030-4444USA Botany The Field Museum1400 South Lake Shore DriveChicagoIL 60605-2496USA

As part of an ongoing comprehensive inventory of Galapagos lichens,a first assessment of the morphology and anatomy of basidiolichens from the archipelago is presented *** is the basis for further studies of the taxonomy,ecology and biogeography of this poorly known group of *** genera,all in Hygrophoraceae,can be distinguished:Acantholichen,Cora,Cyphellostereum and *** Acantholichen and Cora are characterized by chroococcoid cyanobionts and a heteromerous thallus with a distinct upper cortex and photobiont *** monotypic Acantholichen pannarioides is entirely composed of small,branched,inflated squamules that appear densely pruinose because their cortical hyphae bear characteristically swollen,densely spinose end cells(acanthohyphidia);this species has never been observed *** common Cora glabrata is foliose,forming large,radially zonate,conch-like,often tiled thalli,when fertile with circular lines of basidiocarps on its lower *** is distinguished by filamentous cyanobionts and distinctly filamentous thalli that are homomereous(i.e.,not distinctly layered);all species of Dictyonema *** trichomes(filamentose cyanobacterial photobionts)closely enveloped by fungal cells of a jigsaw *** *** thallus filaments(i.e.,individual fibrils)aggregate to form shelf-like structures similar in appearance to polyporoid bracket fungi;basidiocarps develop in irregular patches on the lower side of these *** contrast,fibrils of *** grow encrusting their substrate with irregularly to suberect trichomes,occasionally bearing basidiocarps dispersed across the *** other species in Galapagos show adpressed growth form and are described here as new:Dictyonema pectinatum,which is characterized by large parallel fibrils with paler,papillate tips,and ***,characterized by thin trichomes of more squarrish elongate *** genus Cyphellostereum is represented by two species:the newly describ

关键词： Census of Galapagos Biodiversity Galapagos Lichen Inventory Acantholichen Cora Cyphellostereum Dictyonema

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Enhancing sensitivity of triple-negative breast cancer to DNA-damaging therapy through chemical inhibition of the m6A methyltransferase METTL3

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Cancer Communications 2024年第2期44卷 282-286页

作者： Bianca Cesaro Alessia Iaiza Fabio Piscopo Marco Tarullo Eleonora Cesari Dante Rotili Antonello Mai Alberto Diana Michela Londero Luca Del Giacco Riccardo Masetti alba Di Leone Chiara Naro Silvia Masciarelli Giulia Fontemaggi Claudio Sette Francesco Fazi Alessandro Fatica Department of Anatomical HistologicalForensic&Orthopedic SciencesSection of Histology&Medical EmbryologySapienza University of RomeRomeItaly Department of Biology and Biotechnologies“Charles Darwin” Sapienza University of RomeRomeItaly GSTeP Organoids Research Core Facility Fondazione Policlinico A.Gemelli Istituto di Ricovero e Cura a Carattere Scientifico(IRCCS)RomeItaly Department of Drug Chemistry and Technologies Sapienza University of RomeRomeItaly Pasteur Institute Cenci-Bolognetti FoundationSapienza University of RomeRomeItaly Department of BioSciences University of MilanMilanItaly Multidisciplinary Breast Center Dipartimento Scienze della Salute della Donna e del Bambino e di SanitàPubblicaCatholic University of the Sacred HeartRomeItaly Department of Neuroscience Section of Human AnatomyCatholic University of the Sacred HeartRomeItaly Oncogenomic and Epigenetic Unit IRCCS Regina Elena National Cancer InstituteRomeItaly

Dear Editor,N 6-methyladenosine(m^(6)A)is a critical mRNA modi-fication catalyzed by the enzyme methyltransferase-like 3(METTL3),with implications in RNA ***3 upregulation is associated with cancer progres-sion,metast... 详细信息

关键词： cancer methyltransferase metastasis

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Prostaglandin E1 administration post liver transplantation and renal outcomes:A retrospective single center experience

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World Journal of Transplantation 2024年第4期14卷 101-109页

作者： Vinay Jahagirdar Mohamed Ahmed Ifrah Fatima Hassam Ali Laura alba John H Helzberg Lee S Cummings Matthew Wilkinson Jameson Forster Alisa Likhitsup Department of Internal Medicine Saint Luke’s Health System of Kansas City and the University of Missouri-Kansas CityKansas CityMO 64111United States Department of Gastroenterology and Hepatology East Carolina University Brody School of MedicineGreenvilleNC 27834United States Division of Internal Medicine Department of Gastroenterology and HepatologySaint Luke’s Health System of Kansas City and University of Missouri-Kansas CityKansas CityMO 64111United States Department of Surgery University of Missouri-Kansas City and Transplant SurgerySaint Luke’s Hospital of Kansas CityKansas CityMO 64111United States Department of Gastroenterology and Hepatology University of MichiganAnn ArborMI 48109United States

BACKGROUND Prostaglandin E1(PGE1),or alprostadil,is a potent vasodilator that improves hepatic blood flow and reduces ischemia-reperfusion injury post-liver transplantation(LT).However,the benefits of PGE1 on renal function after LT have not yet been well *** To assess the impact of PGE1 administration on renal function in patients who underwent liver or liver-kidney *** This retrospective study included all patients who underwent liver or liverkidney transplant at our institution from January,2011 to December,*** were classified based on whether they received ***1 was administered post-LT to those with transaminases>1000 U/L in the immediate postoperative ***,post-LT treatments and/or complications,renal function,and survival were *** logistic regression analysis was performed,and a two-tailed P valuey *** A total of 145 patients underwent LT,with 44(30%)receiving *** patient characteristics were comparable,except the PGE1 group had significantly higher aspartate aminotransferase(AST)(1961.9 U/L±1862.3 U/L vs 878 U/L±741.4 U/L,P=0.000),alanine aminotransferase(1070.6 U/L±895 U/L vs 547.7 U/L±410 U/L,P=0.000),international normalized ratio on post-LT day 1(2±0.74 vs 1.8±0.4,P=0.03),a longer intensive care unit stay(8.1 days±11.8 days vs 3.8 days±4.6 days,P=0.003),more vasopressor use(55.53 hours±111 hours vs 16.33 hours±26.3 hours,P=0.002),and higher immediate postoperative complications(18.6%vs 4.9%,P=0.04).The PGE1 group also had a significantly higher 90-day readmission rate(29.6%vs 13.1%,P=0.02)and lower 1-year liver graft survival(87.5%vs 98.9%,P=0.005).However,30-day readmission(31.6%vs 27.4%,P=0.64),LT complications(hepatic artery thrombosis,biliary complications,rejection of liver graft,cardiomyopathy),1-year patient survival(96.9%vs 97.8%,P=0.77),overall liver graft survival,and overall patient survival were similar between t

关键词： Liver transplantation Alprostadil Protective agents Transplant Prostaglandin E1

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Effect of intensity and duration of anthropic noises on European mink locomotor activity and fecal cortisol metabolite levels

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Current Zoology 2022年第6期68卷 688-699页

作者： Lorena ORTIZ-JIMEnez Carlos IGLESIAS-MERCHAN alba Itzel MARTınez-SALAZAR Isabel BARJA Department of Biology Zoology UnitUniversidad Autonoma de MadridMadrid28049Spain Department of Forest and Environmental Engineering and Management Universidad Politecnica de MadridMadridSpain Geographic Information Systems Laboratory Institute of BiologyUniversidad Nacional Autonoma de MexicoMexico CityMexico Biodiversity and Global Change Research Centre(CIBC-UAM) Universidad Autonoma de MadridMadridSpain

Human activities involving noise emission can affect wild *** mink was exposed to road noise and human voice playbacks to analyze how sound intensity level and duration of both noises altered the time that individuals were active and if their fecal cortisol metabolite(FCM)levels varied.A Hierarchical Analysis Cluster was performed to establish 2 mink groups with respect to both noise source type:short duration/low intensity(SL)and long duration/high intensity(LH).We performed general linear mixed models to evaluate the variation in locomotor activity duration(s)and FCM(nanogram per gram)levels,*** results showed both road noise and human voices decreased locomotor activity duration in SL more sharply compared with LH,and human voices were the triggers that induced the most pronounced response to both exposure ***(ng/g)levels increased in SL compared with LH during road noise while the opposite happened during human *** based on sex and age of individuals were *** conclusion,noise characteristics given by the sound type determined the variations in locomotor activity duration while noise exposure level determined the variations in FCM(ng/g)*** should be paid to noisy activities(e.g.,recreational activities for visitors in protected natural areas)and loud groups of people to conserve wildlife,especially noise sensitive species.

关键词： anthropic disturbances European mink fecal cortisol metabolites noise exposure locomotor activity behavioral response

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Coseismic site response and slope instability using periodic boundary conditions in the material point method

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Journal of Rock Mechanics and Geotechnical Engineering 2023年第3期15卷 641-658页

作者： Abdelrahman Alsardi alba yerro Department of Civil and Environmental Engineering Virginia TechBlacksburg24060VirginiaUSA

This paper proposed the explicit generalized-a time scheme and periodic boundary conditions in the material point method(MPM)for the simulation of coseismic site *** proposed boundary condition uses an intuitive particle-relocation algorithm ensuring material points always remain within the computational *** explicit generalized-a time scheme was implemented in MPM to enable the damping of spurious high frequency ***,the MPM was verified against finite element method(FEM).Secondly,ability of the MPM in capturing the analytical transfer function was ***,a symmetric embankment was adopted to investigate the effects of ground motion arias intensity(I_(a)),geometry dimensions,and constitutive *** results show that the larger the model size,the higher the crest runout and settlement for the same ground *** using a Mohr-Coulomb model,the crest runout increases with increasing I_(a).However,if the strain-softening law is activated,the results are less influenced by the ground ***,the MPM results were compared with the Newmark sliding block *** simplified analysis herein highlights the capabilities of MPM to capture the full deformation process for earthquake engineering applications,the importance of geometry characterization,and the selection of appropriate constitutive models when simulating coseismic site response and subsequent large deformations.

关键词： Coseismic site response Periodic conditions Time integration Material point method(MPM)

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Oil recovery tests with ionic liquids: A review and evaluation of 1-decyl-3-methylimidazolium triflate

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Petroleum Science 2022年第4期19卷 1877-1887页

作者： alba Somoza Alberto Arce Ana Soto CRETUS Department of Chemical EngineeringUniversidade de Santiago de CompostelaE-15782Santiago de CompostelaSpain School of Engineering Universidade de A CorunaE-15403FerrolSpain

The main advantages of the use of ionic liquids in enhanced oil recovery are their tunability and stability in harsh environmental conditions. In this work, a comprehensive review of ionic liquids proposed to improve current chemical oil recovery methods has been presented, focusing on core flooding experiments. With an almost infinite number of possible ionic liquids, the amount of experiments carried out up to now has been very limited. However, results are promising, with additional recovery after secondary flooding of up to 32% of the original oil in place. Most formulations with ionic liquids have been proposed for sandstone reservoirs, the number of studies with carbonate cores being very scarce. The possibilities of a new room temperature surface active ionic liquid, 1-decyl-3-methylimidazolium triflate,for this application were analyzed. It was shown that it is able to drastically reduce the water/oil interfacial tension. An optimized formulation was proposed for carbonate reservoirs. After secondary flooding with brine, an additional recovery of 10.5% of original oil in place was achieved at room conditions. A combination of the proposed method followed by a polymer flooding step with polyacrylamide led to a lesser but still significant recovery, reducing the costs associated to the ionic liquid.

关键词： Enhanced oil recovery(EOR) Ionic liquids Core flooding Interfacial tension 1-Decyl-3-methylimidazolium triflate

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Diet,H pylori infection and gastric cancer:Evidence and controversies

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World Journal of Gastroenterology 2007年第21期13卷 2901-2912页

作者： alba Rocco Gerardo Nardone Department of Clinical and Experimental Medicine Gastroenterology UnitUniversity "Federico Ⅱ"Naples Italy

Despite decreasing incidence and mortality rates, gastric cancer (GC) still remains the fourth most common cancer and the second most common cause of cancer-related deaths worldwide. Due to the limited treatment options, at present, prevention is likely to be the only effective means of controlling this disease. The success of a prevention strategy depends upon the understanding of etiological and pathogenic mechanisms underlying gastric carcinogenesis. The etiology of GC is multi-factorial, however, in the recent years, mounting evidence suggests that environmental factors play a key role. The most important environmental factors implicated in the pathogenesis of GC are diet and H pylori infection. Thus, modifications in lifestyle and dietary habit associated with eradication of H pylori infection could hypothetically represent the most promising potential targets for GC prevention. In this review we will address the evidence and the controversies on the role of these agents in noncardia GC by focusing on retrospective and prospective observational studies and interventional trials.

关键词： Gastric cancer Hpylori Diet Observational studies Interventional dietary trials

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Endoscopic resection for early gastric cancer:Towards a global understanding

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World Journal of Gastroenterology 2022年第13期28卷 1377-1379页

作者： alba Panarese Department of Gastroenterology and Digestive Endoscopy Central HospitalTaranto 74123Italy

Gastric cancer is widespread globally,and disease diagnosis is accompanied by high mortality and morbidity ***,prognoses and survivability have improved following implementation of surveillance and screening programs,which have led to earlier ***,early diagnosis itself supports increased surgical curability,which is the main treatment goal and guides therapeutic *** most recent Japanese guidelines for endoscopic submucosal dissection and endoscopic mucosal resection for early gastric cancer consider the degree of endoscopic curability in relation to the characteristics of the gastric *** clinical practice,the management approach for both prevention and treatment should be similar to that of colon lesions;however,unlike the established practices for colorectal cancer,the diagnostic and therapeutic pathways are not shared nor widespread for gastric ***,this negatively impacts the opportunity to perform an endoscopic resection with curative intent.

关键词： Early gastric cancer Artificial intelligence Malignancy Helicobacter pylori Autoimmune gastritis Dysplasia

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3an erectile function be predicted after prostate cancer Ireatment？

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Asian Journal of Andrology 2012年第1期14卷 134-135页

作者： Frances M alba Run Wang Division of Urology University of Texas Medical School at Houston and Department of Urology University of Texas Medical School at Houston Houston TX 77030 USA University of Texas MD Anderson Cancer Center Houston TX 77030 USA

Prostate cancer （PCa） is the most common solid-organ cancer in American males and the second most common cause of cancer-related death in men. With the advent of prostate-specific antigen screening, death from PCa continues to decline. However, recent evidence suggests that there is now a trend towards increasing incidence.1 Current screening strategies result in increased incidence of low-risk PCa and importantly, the diagnosis of PCa is becoming more common in younger patients.2 The majority of early-stage PCa patients have a high likelihood of disease free survival after treatment.

关键词： Prostate cancer prostate-specific antigen screening radical prostatecomy external beam radiation therapy brachytehrapy HRQOL

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Discovering the type of seed dormancy and temperature requirements for seed germination of Gentiana lutea ***(Gentianaceae)

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Journal of Plant Ecology 2018年第2期11卷 308-316页

作者： alba Cuena-Lombraña Marco Porceddu Caterina Angela Dettori1 and Gianluigi Bacchetta1 21 Centro Conservazione BiodiversitàDipartimento di Scienze della Vita e dell’AmbienteUniversitàdegli Studi di CagliariViale S.Ignazio da Laconi11-13Cagliari 09123Italy Banca del Germoplasma della Sardegna(BG-SAR) Hortus Botanicus Karalitanus(HBK)Universitàdegli Studi di Cagliari.Viale Sant’Ignazio da Laconi9-11Cagliari 09123Italy

Aims There are a number of mechanisms that regulate germination;among these,seed dormancy,one of the most important,is an adaptative mechanism in plants to promote survival by dispersing germination in space and time until environmental conditions are favourable for *** main goals of this study were to determine the tem-perature requirements for seed dormancy release and germination of Gentiana lutea ***,to identify the class and level of seed dormancy and to suggest an optimal germination *** Seeds belonging to two different localities were subjected to vari-ous pre-treatments,including cold stratification(0 and 5°C),warm stratification(25/10°C)and different combinations of these,and then incubated at a range of constant temperatures(5-25°C)and 25/10°*** growth during pre-treatments and incubation con-ditions were assessed at different times by measuring the embryo to seed length ratio(E:S ratio).The final germination percentage(FGP)and the germination rate(t50)were *** Findings Fleshy mature seeds of *** *** have linear under-developed *** stratification at 0°C was effective in overcoming the physiological dormancy(PD)and promoted embryo growth and subsequent *** cold stratifica-tion at 0°C,both the root and the shoot emerged readily under a wide range of *** *** seeds showed an intermediate complex morphophysiological dormancy(MPD).As regards the optimal germination protocol for this taxon,we suggest a period of cold stratification at ca.0°C followed by seed incuba-tion at 10-20°*** optimal germination temperatures found for seeds of this taxon,as well as its pre-chilling requirement at 0°C,suggest that it is well adapted to a temperate climate;this behavior highlights an increasing threat from global warming for ***,which could reduce the level of natural emergence in the field,prejudicing also the long-term persistence of the natural popula-t

关键词： embryo growth global warming morphophysiological dormancy pre-chilling requirement seed germination threatened species

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