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Genes & Diseases 2023年第6期10卷 2210-2214页

作者： Mathieu Adjemout Bruno Pouvelle Fatou thiam alassane thiam Magali Torres Samia Nisar Babacar Mbengue Alioune Dieye Pascal Rihet Sandrine Marquet Institut National de la SantéEt de la Recherche Médicale(INSERM) UnitéMixte de Recherche(UMR)U1090Aix Marseille UniversitéTAGC Theories and Approaches of Genomic ComplexityInstitut MarMaRaMarseilleFrance Groupe de Recherche Biotechnologie Appliquée et Bioprocédés Environnementaux(GRBA-BE) Ecole Supérieure PolytechniqueUniversitéCheikh Anta Diop de DakarDakar BP5005Senegal Pole D’Immunophysiopathologie&Maladies Infectieuses(IMI) Institut Pasteur de DakarDakar BP 220Senegal Service D’Immunologie UniversitéCheikh Anta Diop de DakarDakar BP5005Senegal Aix Marseille University CNRSMarseille 13009France

Malaria caused by the Plasmodium falciparum parasite is responsible for more than 240 million cases per year and killed 627,000 people in 2020,mostly African *** malaria parasite is transmitted by mosquitos belonging to the genus *** an asymptomatic liver stage,the parasite is released into the bloodstream to invade red blood cells(RBCs)and replicate *** erythrocytic phase is associated with a variety of clinical manifestations,including mild and severe *** malaria(CM)is one of the most severe forms,characterized by the sequestration of parasitized RBCs in the small capillaries of the brain and the local development of cytokine-mediated *** variants in genes encoding proteins involved in red blood cell physiology are protective factors against severe malaria,as clearly demonstrated for the sickle cell variant of hemoglobin(HbS).

关键词： malaria falciparum Plasmodium

Characterizations of Drinking Water Quality for Populations of Hann Bel-Air (Dakar, Senegal)

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Journal of Water Resource and Protection 2020年第10期12卷 898-909页

作者： alassane thiam Amadou Babacar Sarr Serigne Modou Sarr UFR Sciences de l’Ingénieur Université de Thiès Thiès Sénégal Institut de Formation et de Recherches Médicales Dakar Sénégal Institut Supérieur de Formation Agricole et Rurale Université Alioune Diop Bambey Sénégal

Populations of Hann Bel-Air municipality are supplied with drinking water from taps water of “Sénégalaise Des Eaux” (SDE) and Jambar pumps which capturie directly the groundwater. This municipality is characterized by a strong environmental pollution which can affect the quality of drinking water. To determine actual quality of that water, 10 samples were taken and analyzed. Physico-chemical results have shown that tap water is more suitable for domestic consumption than Jambar pump water. The results show that physical parameters such as electrical conductivity (maximum value of 2671 μS/cm) exceed World Health Organization standard. The pH of the water from Jambar pumps is between 6.04 and 6.09, which demonstrates the aggressive character of that water. For tap water, pH values of 7.03 to 7.09 demonstrate their alkalinity. For chemical analyses, bicarbonates and sulphates concentrations respectively meet World Health Organization standards. Tap water meets World Health Organization standard for nitrates. With respect to chloride, the threshold of 250 mg/L is exceeded at all levels, but we note that high chloride concentrations are part of the exemptions granted to SDE. Tap water and water from water table have concentrations of calcium, potassium, iron and magnesium irreproachable. For sodium, EP3, EP4 and P5 samples from the web exceed World Health Organization standard with a peak of 310.27 mg/L. Tap water is more drinkable than groundwater but its quality needs to be improved and especially controlled for the well-being and sustainable health of consumers.

关键词： Hann Bel-Air Water Resources Physico-Chemical Analyses Quality

Multidisciplinary Approach for a Solution to Floods in SampathéDistrict (Thiès-Est, Senegal)

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Journal of Geographic Information System 2020年第6期12卷 663-682页

作者： Mouhamadou Moustapha Mbacké Ndour alassane thiam Bakary Fall Ibrahima Seye Unité de Formation et de Recherches-Sciences de l’Ingénieur Université of Thiès Thiès Sénégal Centre de Suivi Ecologique Dakar Sénégal Grande Cô te Opération Sa Dakar Sénégal

In recent years (2003), Senegal has been confronted with many urban flooding problems that have become recurrent due to the configuration of its settlement. This is due to galloping population growth, climate change and a lack of planning and rainwater drainage networks. To fix these phenomena, Senegalese government has initiated rainwater drainage programs. In the city of Thiès, particularly in Sampathé district, flooding problem is a reality that is observed during every winter period. It is within this framework that we have proposed a project for the design and dimensioning of a rainwater evacuation network in Sampathé. The network will be integrated into a Geographic Information System for efficient management of project. This study involved identifying flood zones, determining geotechnical characteristics of the soil, and exploiting rainfall data in order to propose a storm water drainage network that will be integrated into a database management system. Thus, we carried out topographical and geotechnical studies, then designed and dimensioned the drainage network, and finally set up a geographic information system. At the end of this project, we designed a sewerage network consisting of two primary pipelines, four secondary pipelines, one tertiary pipeline, ninety-two manholes and a retention basin. To manage the network, we set up a geographic information system to geolocate various elements for rapid intervention in the field in event of a problem, make requests, generate thematic maps, and perform spatial analyses for good decision-making.

关键词： Flood Flooding Sewerage Network Topographic Surveys Geographic Information System Sampathé

Reassessment of the Resources of a Deep Aquifer System under Physical and Chemical Constraints:The Maastrichtian Aquifer

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Journal of Water Resource and Protection 2012年第4期4卷 217-223页

作者： Cheikh Hamidou Kane Moustapha Diene Meissa Fall Baba Sarr alassane thiam Département de Géologie FST-UCAD Cheikh Anta Diop University Dakar Senegal ISRA Bambey Senegal Laboratoire de Géologie IFAN Cheikh Anta Diop University Dakar Senegal Laboratoire de Mécanique et Modélisation-UFR Sciences de l’Ingénieur University of Thiès Thiès Senegal

The deep and confined Maastrichtian aquifer contains considerable groundwater resources. It stretches over nearly 200,000 km2, from the northern part of Mauritania to the South of Guinea Bissau where it becomes shallow. The reservoir is composed mainly of coarse sands and sandstone interbedded with some clay units. The aquifer provides 40% of the total drinking water extracted from the different aquifers and nearly 800 wells equally distributed operate only in the top 50 m of the aquifer. Despite the importance of these resources for providing water in the rural and urban areas, the aquifer characteristics are not well defined. The present paper aims to define first the physical and chemical characteristics of the Maastrichtian aquifer. The reserve of the aquifer initially estimated at 350 billion m3, is reassessed using new data providing from cross sections realized as part of our research, through the Water Sectorial Project of the Ministry of Hydraulics. Data from oil wells and geophysical logging are used to investigate the geometry of the aquifer and the position of the fresh/salty water interface. The highest thickness of the aquifer is between 200 to 400 m and salty water is present below the fresh groundwater in the west side of the aquifer. In the Eastern side, potable water lies directly above the basement. The thickness of the aquifer increases from the west to the center, and then decreases towards the shallow basement rock in the South East. The average thickness is 250 m. Chemical data coming from pumping wells indicate high chloride (250 - 1600 mg/l) and fluoride content (1 - 5.5 mg/l). Therefore, the reassessment has to take into account the chemical aspect of the water.

关键词： Maastrichtian Groundwater Deep Aquifer Senegalese-Mauritanian Sedimentary Basin Characteristic Pollution Reassessment

Influence of Mechanical Properties of Concrete and Soil on Solicitations of Mat Foundation

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Open Journal of Civil Engineering 2015年第2期5卷 249-260页

作者： Oustasse Abdoulaye Sall Makhaly Ba Mapathé Ndiaye Daouda Sangare Mathioro Fall alassane thiam Dé partement de Gé nie Civil UFR SI-Universit&eacute de Thiè s Thi&egrave s S&eacute né gal Dé partement de Mathé matiques UFR SAT-Universit&eacute Gaston Berger Saint Louis S&eacute né gal

This work studies the influence of mechanical and geometrical characteristics of the concrete and the soil on the stresses in a mat foundation. In this study, the soil-structure interaction is modeled by two parameters, the modulus of subgrade vertical reaction (k) and the modulus of subgrade horizontal reaction (2T). These two parameters are dependent on the geometrical and mechanical characteristics of the system. Results of this study show a sensitivity of solicitations to variations of geometrical and mechanical characteristics of the model. Although solicitations in the plate are sensitive to mechanical properties of concrete, these solicitations are strongly influenced by the mechanical and geometrical characteristics of the soil mass. However, it should be noted that the influence of Eb is denoted in the center of the plate whereas the Es feels almost in the same manner over the entire extent of the plate. This study also shows that for the same load cases, the values of the torsion moment and shear stress are not significant those of bending moments and normal stresses, respectively.

关键词： Plate Soil-Structure Interaction Mechanical Properties Modeling Solicitations

Investigating the Depth and the Geometry of the Quarzitic Panafrican Basement Using Near-Surface 3D Seismic Refraction Tomography: Case Study of the Locality of Bakel (Senegal)

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International Journal of Geosciences 2020年第6期11卷 345-359页

作者： Mapathe Ndiaye Oustasse Abdoulaye Sall alassane thiam Déthié Sarr Moustapha Badji Issa Ndoye Laboratory of Mechanics and Modeling Faculty of Engineering University of Thies Thies Senegal

Seismic refraction investigations have been carried out in Bakel, Eastern Senegal. The purpose was to map geometrical relationship between the existing rock types and the Panafrican quarzitic basement, which is valuable information for the project of the Bakel fluviatile port construction. Four seismic refraction profiles were acquired. The obtained data have been processed by inversion. The obtained four seismic P-wave velocity profiles have been integrated to obtain a 3D model. By comparing the outcropping geological formations with the observed seismic data at the surface, it was possible to identify the lithology corresponding to each measured range of seismic velocity for the alluvium, the weathered bed rock, and the fresh rock. The results showed that the depth of the fresh rock of the basement varies from 0 to 18 meters above the sea level, with a deepening toward the Senegal River and toward the Northern part of the studied area. The presence of alluviums and their thickness are linked to the existence of bays and gulfs. The results of this study give valuable information for the river bed dredging cost assessment prior to the port construction phase.

关键词： Panafrican Alluvium Quartzite Seismic Refraction Tomography 3D Model Bakel Senegal

Biogeochemical Dynamics of Molybdenum in a Crater Lake:Seasonal Impact and Long-Term Removal

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Journal of Water Resource and Protection 2014年第4期6卷 256-271页

作者： alassane thiam Didier Jezequel Alexis Groleau Francois Prevot Filipa Lopes Patrick Alberic Catherine Quiblier Elivira Bura-Nakic Irena Ciglenecki Hassiba Lazar Eric Viollier Universite de Thies UFR Sciences de l’IngenieurThiesSenegal Laboratoire de Geochimie des Eaux Universite Paris Diderot-Institut de Physique du Globe de ParisParisFrance Laboratoires Genie des Procedes et Materiaux Ecole de Chimie de ParisChatenay-MalabryFrance UMR611-CNRS/Universite d’Orleans OrleansFrance Museum National d’Histoire Naturelle Equipe“Systematique et Ecotoxicologie des Micro-Algues”ParisFrance Rudjer Boskovic Institute Center for Marine and Environmental ResearchZagrebCroatia

Despite a large variety of processes that can control Mo and its potential to become an environmental tracer of euxinic environment, this element is not often studied in lakes. The aim of this paper is to identify main seasonal biogeochemical processes that involve Mo in a well constrained freshwater system (Lake Pavin water-column) in order to evaluate their respective importance. In Lake Pavin, 4 main processes have been identified: 1) the transitional process represented by Mo assimilation of by phytoplankton in the epilimnion (nitrogen biological fixation and nitrate assimilation);2) transient process represented by dissolved Mo adsorption onto Fe and Mn metal oxides at oxic/anoxic interface (depth 50 - 60 m);3) Mo precipitation where apparent sulfide production rate is maximum, and from 80 m depths;4) release of dissolved Mo due to Mo benthic flux or input from a deep source.

关键词： Molybdenum Biogeochemical Cycles Diatoms ICP-MS Meromictic Lake

One-Dimensional Study of Thermal Behavior of Typha Panel: Spectroscopy Characterization of Heat Exchange Coefficient on Front Face

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Journal of Sustainable Bioenergy Systems 2020年第2期10卷 52-61页

作者： Sokhna Khadidiatou Ben thiam alassane Ba Mamadou Babacar Ndiaye Issa Diagne Youssou Traore Seydou Faye Cheikh thiam Pape Touty Traore Ablaye Fame Gregoire Sissoko Ecole Polytechnique de Thiès (EPT) Thiès Senegal University Institute of Technology University of Thiès Thiès Senegal Laboratory of Semiconductors and Solar Energy Physics Department Faculty of Science and Technology University Cheikh Anta Diop Dakar Senegal

Convective heat transfer coefficients, materializing exchanges between solid wall (here typha) and its environment, influence its behavior under excitation pulse. Temperature of wall and its density of flow vary with these coefficients according to its thickness (in depth). This study therefore focuses on the evaluation of convective heat transfer coefficient on front face and the optimal insulation thickness.

关键词： Typha Heat Transfer Coefficients Spectroscopy Optimal Insulation Thickness

GNSS Technology’s Contribution to Topography: Evaluative Study of Gaps between Methods Topographies

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Journal of Geographic Information System 2021年第3期13卷 340-352页

作者： Cheikh Ahmed Tidiane Ly Joseph Mbagnick Louis Diene Diogoye Diouf alassane Ba Unité de Formation et de Recherches-Sciences de l’Ingénieur Université Iba Der THIAM of Thiès Thiès Sénégal Ecole Polytechnique de Thiès Thiès Sénégal

New information and communication technologies have led to the emergence of new techniques in our daily lives. Indeed, in topography, a lightning development of new techniques and new devices has been noticed. This development has given rise to a multitude of choices of devices and various classes of precision. This implies that the decision-makers have to study the adequate equipment and the appropriate technique according to the topographic task to be realized. The objective is not to compare GNSS and topographic techniques, but to point out the contribution of the Global Navigation Satelite System (GNSS) techniques of topographic work. Thus, a theoretical study with a critical eye on the scientific principle of calculating the third topographic dimension followed by a leveling campaign, Real Time Kinematic (RTK) surveys will be used in order to be able to compare and interpret the result from these campaigns. The study of the difference resulting from the practical campaigns will allow us to identify the contribution of GNSS technology.

关键词： Topography GNSS Technic Accuracy Contribution

Influence of Heat Exchange Coefficients on Both Optimized Thermal Contact (OTCR) and Critical (CTCR) Resistances at the Contact Interface of a Flat Concrete Slab and a Rice Straw Board

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Energy and Power Engineering 2021年第12期13卷 392-402页

作者： alassane Diene Mamadou Lamine Lo Abdoulaye Sene Ablaye Fame Youssou Traore Seydou Faye Issa Diagne Mamadou Babacar Ndiaye Gregoire Sissoko Polytechnic School of Thiès Thiès Senegal Laboratory of Semiconductors and Solar Energy Physics Department Faculty of Science and Technology University Cheikh Anta Diop Dakar Senegal University Institute of Technology University Iba Der THIAM of Thiès Thiès Sénégal Groupe International de Recherche en Energie Renouvelable Dakar Senegal

The study is carried out in imperfect contact with a concrete slab wall attached to a panel based on rice straw compressed in a dynamic frequency regime. We will propose the characterization of thermal insulation for thermal resistance of contact (x = 0.05 m). The impact of heat exchange coefficients on the front face (x = 0 m) and the rear face (x = 0.1 m) on these resistors is shown.

关键词： Concrete Slab Rice Straw Board Thermal Resistance of Contact Frequency Dynamic