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Carotid Web as a Cause of Ischemic Stroke in Sub-Saharan Africa: A Preliminary Monocentric Descriptive Study of 6 Cases Collected at the Fann Teaching Hospital (Senegal)

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World Journal of Cardiovascular Diseases 2022年第3期12卷 133-139页

作者： Ndiaga Matar Gaye alassane Mamadou Diop Adjaratou Dieynabou Sow Abdoul Salam Soumaré Didier Smadja Moustapha Ndiaye Sokhna Ba Amadou Gallo Diop Neurology Department Fann Teaching Hospital Dakar Senegal Stroke Unit Centre Hospitalier Sud-Francilien Corbeil-Essones France Radiology Department Fann Teaching Hospital Dakar Senegal

Introduction: Carotid web (CW), a rare and probably unknown arterial cause of ischemic stroke (IS), is commonly reported in young black patients, although most of the published cases resided in a non-African country. We describe the features of the first six Senegalese cases diagnosed at the Neurology Department of the Fann Teaching Hospital in Dakar. Patients and Method: It was a preliminary retrospective and prospective study conducted at the Neurology department of Fann teaching hospital (Dakar-Senegal). The symptomatic CW diagnosis was based on angioCT-scan of the neck arteries. The National Institute of Health Stroke Scale (NIHSS) and the modified-Rankin Scale (mRS) were used to assess the severity of the IS and the functional disability after the event, respectively. Results: CW was causing a left sylvian infarction in 4 patients. The mean age of the patients at the IS diagnosis was 41 ± 6 years with a sex ratio of 1. The mean time to diagnosis of CW was 13 months. Smoking (1/6), hypertension (1/6), and obesity (1/6) were the main vascular risk factors. The mean LDL cholesterol level was 1.52 g/L ± 0.49. The mean initial NIHSS was 15 ± 6 (8-22). Half of the patients had a severe infarction (NIHSS ≥ 15). For secondary prevention, half of the patients were treated with aspirin and the other half with acenocoumarol. After 18 months ± 17 of follow-up, the mean mRS score was 2 ± 1 (1-3). Conclusion: CW is an unknown cause of IS in young black patients. An early and appropriate multidisciplinary management could help to reduce the risk of recurrences.

关键词： Carotid Web Sub-Saharan Africa Senegal AngioCT-Scan Acenocoumarol

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Diabetes Ketoacidosis in Pregnancy: A Retrospective Study from the Teaching Hospital of Pikine

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Open Journal of Endocrine and Metabolic Diseases 2023年第6期13卷 75-83页

作者： Nafy Ndiaye Ngone Diaba Diack Abdou Tall Khadidiatou Samb Yakham Mohamed Leye Abdoulaye Leye Abdou Aziz Diouf alassane Diouf Internal Medicine/Endocrinology-Diabetology Department Teaching Hospital of Pikine Cheikh Anta Diop University Dakar Senegal Department of Gynaecology-Obstetric Teaching Hospital of Pikine Cheikh Anta Diop University Dakar Senegal

Introduction: Diabetic ketoacidosis (DKA) in pregnancy is rare but associated with maternal and foetal morbidity and mortality. The objectives of this study were to evaluate the epidemiological, diagnostic, and prognostic characteristics of DKA in pregnant women in Dakar hospitals and to study the predictive factors of its occurrence. Methods: This retrospective study was conducted from January 2013 to January 2021 in the Internal Medicine/ Endocrinology-Diabetology-Nutrition and Gynaecology-Obstetrics departments of the National University Hospital Centre in Pikine, Senegal. Medical files of all pregnant women hospitalised for DKA during this period were collected. Results: A total of 10 patients were included in the study. Average age was 30.9 years. Two patients with unplanned pregnancies had pre-gestational diabetes mellitus (pre-GDM) and did not have regular diabetic follow-up. Among the 8 patients with GDM, risk factors for GDM were found in 7 women, and three had a history of GDM. Blood glucose levels were >1.02 and >11 g/L for these two groups, respectively. None of the women had been systematically screened for GDM between 24 and 28 gestational weeks. Signs of ketosis were present: 6 patients had Kussmaul dyspnea and one patient had a Glasgow Coma Score of 10/15. The precipitating factor was infection in three patients. Two patients had pre-eclampsia. The evolution of DKA was favourable in all patients. For pregnancy outcomes: 4 cases of intrauterine foetal death were recorded, 2 women carried their pregnancy to term, a woman gives birth prematurely and 3 patients were lost to follow-up. Conclusion: DKA during pregnancy is rare in Dakar hospitals but health risk increases with the lack of screening for GDM in pregnant women, follow-up in a specialised environment, and pregnancy planning in diabetic patients. The obstetrical prognosis is poor for GDM patients, with a high rate of foetal death in utero.

关键词： Diabetic Ketoacidosis Gestational Diabetes Mellitus Pregnancy Pikine Senegal

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Perinatal Deaths in Rural a Health Area, Case of the Health District of Kadiolo, Mali

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Surgical Science 2019年第11期10卷 385-397页

作者： Seydou Fané Amadou Bocoum Youssouf Traoré Abdoulaye Sissoko Ibrahima Tegueté Mamadou Sima Mamadou Salia Traoré Tiounkani Augustin Thera Yaya Sylla alassane Traoré Soumana Oumar Traoré Aminata kouma Niani Mounkoro Gabriel Toure Teaching Hospital Center-Gynecology-Obstetrical Service Bamako Mali Hospital mère enfant le Luxembourg Bamako Mali Point G Teaching Hospital Center of Bamako Bamako Mali Referral Health Center of Kadiolo Sikasso Mali Mali Hospital Bamako Mali Reference Health Center of Commune 6 of Bamako District Bamako Mali Kati Hospital Kati Mali

The perinatal mortality is a public health issue in developing countries. In fact, the perinatal death rate seems the highest in a Malian rural area. The objective of this work was to study the perinatal mortality in a rural area of Mali (Kadiolo). Methodology: It was a cross-sectional descriptive study conducted in Kadiolo over 12 months. The study took place from April 1, 2016 to March 31, 2017. We have included in our study all dead fetuses in gestational age ≥ 28 weeks of amenorrhea (WA) or weight ≥ 500 grams (g) and infants died during the first week of life. Mothers who have experienced a perinatal death were included. Results: During the 12 months of study period, we have recorded a total of 2212 births out of which we have collected 205 perinatal deaths, a perinatal mortality rate of 205/2212 with 93 per 1000. The stillbirth rate was 152/2212 with 69‰ and the early neonatal mortality rate was 53/2212 with 24‰. The sociodemographic characteristic of the patients was: patient who has been evacuated 71.70%, unschooled 77.1%, coming out of the city Kadiolo 76%, young women 65% and patient who did not receive antenatal care 35%. Conclusion: Our study confirms the high rates of perinatal deaths in rural areas. The implementation of a coherent and efficient care strategy should help in reducing the still high rates.

关键词： Perinatal Deaths Dystocia Rural Environment Mali

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Chemotaxonomic Study of the Covid-Organics of Madagascar Based on the Chemical Composition of Their Essential Oils

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International Journal of Organic Chemistry 2023年第2期13卷 50-56页

作者： Yoro Tine Adama Diédhiou Alioune Diallo Idrissa Ndoye Mamadou Baldé Cheikhouna Gaye Benjamin Ndiaye alassane Wélé Djibril Fall Laboratoire de Chimie Organique et Thé rapeutique Facult&eacute de M&eacutedecine Pharmacie et Odontologie Universit&eacute Cheikh Anta Diop Dakar S&eacuten&eacutegal

The aim of this study was to investigate the chemical composition of the essential oils of “Covid-Organics” of Madagascar (62% Artemisia annua and two other undisclosed medicinal plants) used as curative and preventive treatments of Covid-19, to identify its constituent species. The essential oils isolated by hydro-distillation from two samples (curative and preventive) were analyzed by GC-FID and GC-MS. These essential oils (curative and preventive) were mainly dominated by camphor (17.9% and 11.9%, respectively), spathulenol (4.8% and 11.8%, respectively), α-acorenol (4.3% and 3.7%, respectively), (E)-β-caryophyllene (3.4% and 4.2%, respectively), 1,8-cineole (3.1% and 3.6%, respectively), hexadecanoïc acid (3.8% and 3.2%, respectively) and caryophyllene oxide (3.4% and 2.4%, respectively). From the chemical composition, two species were identified, A. annua characterised by camphor and Cinnamomumcamphora (Ravintsara) characterised by 1,8-cineole and sabinene. However, we were unable to identify the third species.

关键词： Covid-19 Covid-Organics Artemisia annua Essential Oils Chemotaxonomic

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Complications Related to the Insertion Technique of Jadelle^® Contraceptive Implants

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Open Journal of Obstetrics and Gynecology 2023年第2期13卷 166-174页

作者： Astou Coly Niassy Moussa Diallo Tatiana Sandjon Ibrahim Rahadat Marie-Édouard Faye Ndeye Fatou Coulibaly alassane Diouf Jean-Charles Moreau Gynecology-Obstetrics Hospital Aristide Le Dantec Dakar Senegal Gynecology-Obstetrics National Hospital Center of Pikine Dakar Senegal Orthopedics-Traumatology Aristide Le Dantec Hospital Dakar Senegal

Introduction: Contraceptive implants are one of the most effective methods of birth spacing. Jadelle® implants consist of two strands that are easy to insert and remove. Although their effectiveness is no longer in question, their use (insertion) requires a surgical procedure with the corollary possibility of complications. These are mainly insertions that are too deep (in the arm muscle), vascular and nerve damage. Material and Methods: Our study focused on complications related to implant insertion. It was a descriptive and retrospective study over thirty-four months, from October 2016 to July 2019, and concerned all patients seen in consultation and who presented a complication related to the insertion of contraceptive implants in the Department of Gynecology and Obstetrics of the National Hospital of Pikine. Results: We collected nine complications managed at the Gynecology and Obstetrics Department of the Centre Hospitalier National de Pikine from 2016 to 2019. These were insertions that were too deep with sometimes nerve damage, infection or incident during anesthesia. The operative procedures were based on the type of complication. Conclusion: Although Jadelle® has the advantage of having only 2 rods compared to its predecessor Norplant®, its use is also conditioned by insertion and removal procedures which may experience complications.

关键词： Contraception Implants Incidents Insertion Removal

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Delayed Management of High-Grade Renal Trauma in a Child with Bilateral Lower Polar Artery: A Case Report

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Open Journal of Urology 2022年第11期12卷 556-562页

作者： Doudou Gueye Florent Tshibwid A. Zeng Ibrahima Bocar Wellé Papa alassane Mbaye Lissoune Cissé Christ Tsague Momo Ndeye Aby Ndoye Aloï se Sagna Gabriel Ngom Department of Pediatric Surgery Albert Royer National Children’s Hospital Centre Université Cheikh Anta Diop Dakar Senegal

High-grade renal trauma rarely occurs due to low-velocity mechanisms. With its clinical presentation, delayed diagnosis rarely happens. We report the case of a 12-year-old girl diagnosed seven days post-trauma with grade IV renal trauma complicated with infected urinoma and bilateral lower polar vessels. She was non-operatively managed with ultrasound-guided percutaneous drainage of the urinoma, which resolved, and had unremarkable six months follow-up. We discuss the role of preexistent hydronephrosis in low-velocity impact, pitfalls of diagnosis in resource-constrained settings, and management of high-grade trauma.

关键词： Renal Trauma Lower Polar Artery Urinoma Delayed Diagnosis Case Report

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The Contribution of the People’s Republic of China to Malian Conflict Resolution (2013-2017)

The Contribution of the People’s Republic of China to Malia...

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作者： alassane Camara 华中师范大学

学位级别：硕士

马里是一个土地辽阔、历史悠久、文化深厚的国家,马里人民多年来为祖国的和平与兴盛不懈努力。从古至今,在寻求社会、经济、文化在国内和国际发展的进程中,这个美丽的文化历史大国的发展之路上既铺满鲜花,也遍布荆棘。尽管如此,国家领... 详细信息

马里是一个土地辽阔、历史悠久、文化深厚的国家,马里人民多年来为祖国的和平与兴盛不懈努力。从古至今,在寻求社会、经济、文化在国内和国际发展的进程中,这个美丽的文化历史大国的发展之路上既铺满鲜花,也遍布荆棘。尽管如此,国家领导人的攻坚克难,加之国际上合作伙伴的多方支持,使得马里所面临的许多发展问题都迎刃而解。本文旨在研究自2012年起由恐怖分子和毒贩在马里北部引起的恐慌和危机。中国自建国以来一直是马里重要的合作伙伴之一,在解决这类冲突性问题时,中国从未袖手旁观。中国与马里的友好关系可以追溯至57年前莫迪博·凯塔总统时期与和毛泽东主席建立的友谊。本文将以中国帮助解决马里国内的冲突问题为切入点,考察两国之间友好的双边关系。中国已与其他国际合作伙伴一道,在联合国马里多层面综合稳定团的维和任务中,尤其是应对马里北部的危机方面做出了突出贡献;除此,中国还在马里境内的人员培训、医疗救助、后勤物资等方面做出了积极贡献,尤其在卫生防预、基础设施和工程建设等主要领域给予了马里人民无私援助。

关键词：非洲联盟马里中华人民共和国解决冲突

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Chemical Variability and Antibacterial Activity of Eucalyptus camaldulensis Essential Oils from Senegal

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International Journal of Organic Chemistry 2022年第4期12卷 173-180页

作者： Yoro Tine Alioune Diallo Idrissa Ndoye Cheikhouna Gaye Benjamin Ndiaye Abdoulaye Diop Jean Costa Cheikh Saad Bouh Boye alassane Wélé Julien Paolini Laboratoire de Chimie Organique et Thérapeutique Faculté de Médecine Pharmacie et Odontologie Université Cheikh Anta Diop Dakar Senegal Université de Corse UMR CNRS 6134 SPE Laboratoire de Chimie des Produits Naturels Campus Grimaldi Corte France Laboratoire de Bactériologie-virologie H&ocirc pital Aristide Le Dantec Dakar Senegal

1,8-cineole, also known as eucalyptol, is the main constituent and the most important of the leaf oils of many species of the genus Eucalyptus. In present study, the essential oils isolated by hydrodistillation from the leaves of Eucalyptus camaldulensis from six different locations were analyzed by GC-FID and GC-MS. Essential oil yields ranged from 0.33% to 4.35%. In total, 34 constituents were identified, accounting for 94.0% to 99.8% of the total compositions. 1,8-cineole (46.4% - 84.4%) was the main constituent of all the essential oil samples, except for one sample collected in the Fatick region, which had p-cymene (46.4%) and 1,8-cineole (26.0%) as major compounds. The essential oil showed excellent activity against S. aureus, E. coli and E. faecalis (IZ = 25.3 ± 1.2 mm;18.7 ± 0.6 mm;17.8 ± 0.3 mm, respectively) and moderate activity against P. aeruginosa (IZ = 10.8 ± 0.8 mm). They may have potential applications in food and pharmaceutical products.

关键词： Eucalyptus camaldulensis Essential Oils Antibacterial Activity 1 8-Cineole and GC-SM

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Parietal Infiltration for Postoperative Analgesia

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Surgical Science 2023年第2期14卷 72-76页

作者： Kanté Lassana Issiaka Diarra Idrissa Tounkara Maiga Amadou Traore Amadou Madiassa Konaté Ibrahima Diakite Dembélé Bakary Tientigui alassane Traore Adegné Togo Faculty of Medicine and Odonto Stomatology (FMOS) General Surgery Department Gabriel Touré University Hospital Center Bamako Mali General Surgery Department of the Reference Health Center of Commune 1 of Bamako District Bamako Mali General Surgery Department of the Reference Health Center of Commune 2 of Bamako District Bamako Mali

The parietal component of pain occupies an important place in the management of postoperative analgesia. Parietal infiltration is a technique that fits into a concept of multimodal analgesia using several analgesic products simultaneously. This simple and reliable technique makes it possible to reduce the use of opioids and therefore their adverse effects;without increasing the risk of infection. It reduces the length of hospitalization.

关键词： Parietal Infiltration Analgesia Surgery

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The Complications of Cesarean Section at Teaching Hospital Gabriel TOURE, Bamako Mali

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Open Journal of Obstetrics and Gynecology 2020年第4期10卷 546-557页

作者： Abdoulaye Sissoko alassane Traore Ibrahim Kante Amadou Bocoum Soumana Oumar Traore Seydou Fane Daniel Dembele Aminata kouma Mamadou Sima Fatoumata K. Tounkara Amadou Fomba Ibrahima Teguete Youssouf Traore Soumaila Keita Niani Moukoro Teaching Hospital Gabriel TOURE Bamako Mali Teaching Hospital Bamako Mali Teaching Hospital Point G Bamako Mali District Hospital Commune V Bamako Mali Teaching Hospital Kati Bamako Mali Research Center CHU of Quebec University of Laval Quebec Canada

Cesarean operation permits to save the mother and fetus. However, in developing countries as ours, complications related to this cesarean are not to be neglected. It constitutes an important cause of maternal and fetal morbidity and mortality. Here we rapport the experience of our structure about the complications of cesarean. Objectives: The objectives of this study were to study the complications the complications of cesarean section at teaching hospital Gabriel TOURE, Bamako Mali. Materials and methods: We have carried out a cross sectional analytic study from January 1st?2003 to December 31st?2013. All the patients who gave birth by cesarean operation in gynecology-obstetric service of teaching hospital Gabriel TOURE were included during this period of study. Descriptive statistics were used, Chi-square test Pearson, and?Cochran Armitage test have?been used to calculate the P-value of trend. We performed multivariate analyses with a high alpha threshold of 10%, and then logistic regression multivariate. Results: We have registered 28,376 deliveries with 9509 cases of cesarean (33.5%) and a complication cesarean rate of 32% (3049/9509). The main risk factors for cesarean operation completions were adolescence primiparity, obesity, the non-realization of antenatal care, evacuations and co-morbidities. Intraoperative complications were dominated by hemorrhage 8.3% and bladder lesion 1.1%, whereas anemia (58.8%) and parietal infection (21.1%) dominated the postoperative complications table. The evacuation (Odds Ratio adjusted (ORa) = 1.96) as well pre-eclampsia/eclampsia?(ORa = 2.34) and the sicle cell disease (ORa = 9.99) were the main influencing factors of material death. Praevia placenta (ORa = 1.75) abruption placenta (ORa = 11.08) and fetal malformation (ORa = 2.21) dominated the influencing factors of perinatal death. Conclusion:?The cesarean complications rates were high in our improvement of the quality of antenatal care.?The reorganization and revitalizati

关键词： Cesarean Complication Risk Factors Morbidity Mortality

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