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An Efficient Method for Epileptic Seizure Detection in Long-Term EEG Recordings

Journal of Biomedical Science and Engineering 2014年第12期7卷 963-972页

作者： alaa eldeen mahmoud helal Ahmed Farag Seddik Mohammed Ali Eldosoky Ayat Allah Farouk Hussein Biomedical Engineering Department Faculty of Engineering Helwan University Cairo Egypt Clinical Neurophysiology Department Faculty of Medicine Cairo University Cairo Egypt

Epilepsy is one of the most prevalent neurological disorders with no age, racial, social class, and neither national nor geographic boundaries. There are 50 million sufferers in the world today with 2.4 million new cases occur each year. Electroencephalogram (EEG) has become a traditional procedure to investigate abnormal functioning of brain activity. Epileptic EEG is usually characterized by short transients and sharp waves as spikes. Identification of such event splays a crucial role in epilepsy diagnosis and treatment. The present study proposes a method to detect three epileptic spike types in EEG recordings based mainly on Template Matching Algorithm including multiple signal-processing approaches. The method was applied to real clinical EEG data of epileptic patients and evaluated according to sensitivity, specificity, selectivity and average detection rate. The promising results illuminate that hybrid processing approaches in temporal, frequency and spatial domains can be a real solution to identify fast EEG transients.

关键词： Electroencephalogram (EEG) Seizure Detection Epilepsy Diagnosis

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Concomitant Chemoradiation Using Gemcitabine in Locally Advanced Hepatocellular Carcinoma

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Journal of Cancer Therapy 2018年第12期9卷 1027-1038页

作者： Mohamed-alaa-eldeen H. Mohamed Department of Clinical Oncology and Nuclear Medicine Faculty of Medicine Assiut University Assiut Egypt

Purpose: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. Most of patients present with advanced disease that cannot be treated with curative or ablative intent. The aim of the study was to assess the therapeutic benefit of concurrent chemoradiotherapy (CCRT) in patients with advanced HCC and to identify factors that predict OS. Methods: Patients with radiologically or biopsy proven primary HCC from 2010 to 2013 were included in the study. Gemcitabine was given in a dose of 70 mg/m2 once weekly for three weeks during external beam radiotherapy 30 Gy/2 Gy/fraction/five fractions per week in the Clinical Oncology Department, Assiut, Egypt. Results: Forty-nine patients were eligible but forty patients were evaluable for assessment. The partial response rate (PR) was 35% (14 patients), 16 patients (40%) had stable disease (SD) and the progressive disease was 25%. Painful hepatomegaly was significantly relieved in 70% of patients. Transaminases rose as grade 3 toxicity in 15% of patients. Longer overall survival (OS) was significantly observed in patients with performance status 0, child-Pugh A, Barcelona Clinic Liver cancer Stage B, PR and α fetoprotein level decrement. Conclusion: Concurrent chemoradiotherapt provides an acceptable response and palliation of pain in advances HCC. Our findings showed that better survival for patients with good performance and liver functions.

关键词： Chemoradiation Gemcitabine Hapatocellular Carcinoma Survival

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Propagation of Electromagnetic Waves in Slab Waveguide Structure Consisting of Chiral Nihility Claddings and Negative-Index Material Core Layer

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Photonic Sensors 2018年第2期8卷 176-187页

作者： alaa N. Abu helal Sofyan A. TAYA Khitam Y. ELWASIFE Physics Department Islamic University of Gaza Gaza 108 Palestine

The dispersion equation of an asymmetric three-layer slab waveguide, in which all layers are chiral materials is presented. Then, the dispersion equation of a symmetric slab waveguide, in which the claddings are chiral materials and the core layer is negative index material, is derived. Normalized cut-off frequencies, field profile, and energies flow of right-handed and left-handed circularly polarized modes are derived and plotted. We consider both odd and even guided modes. Numerical results of guided low-order modes are provided. Some novel features, such as abnormal dispersion curves, are found.

关键词： Slab waveguides chiral materials left-handed materials

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